| scholarly article | Q13442814 |
| P2093 | author name string | Massimo Trucco | |
| Zhong Wang | |||
| Paul D Robbins | |||
| Xiao Xiao | |||
| Khaja K Rehman | |||
| P2860 | cites work | Predominance of T lymphocytes in pancreatic islets and spleen of pre-diabetic non-obese diabetic (NOD) mice: a longitudinal study | Q67298313 |
| Prevention of diabetes in NOD mice treated with antibody to murine IFN gamma | Q67996894 | ||
| In vivo administration of IL-4 induces TGF-beta-producing cells and protects animals from experimental autoimmune encephalomyelitis | Q71026292 | ||
| Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse | Q72415292 | ||
| Overexpression of bcl-2 in T cells affects insulitis in the nonobese diabetic mouse | Q73185464 | ||
| Characterization of peripheral regulatory CD4+ T cells that prevent diabetes onset in nonobese diabetic mice | Q73289663 | ||
| IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function | Q73873358 | ||
| Administration of IL-4 prevents autoimmune diabetes but enhances pancreatic insulitis in NOD mice | Q74214013 | ||
| Oral administration of schistosome egg antigens and insulin B-chain generates and enhances Th2-type responses in NOD mice | Q74518755 | ||
| Multidose streptozotocin induction of diabetes in BALB/cBy mice induces a T cell proliferation defect in thymocytes which is reversible by interleukin-4 | Q74583045 | ||
| Mature mainstream TCR alpha beta+CD4+ thymocytes expressing L-selectin mediate "active tolerance" in the nonobese diabetic mouse | Q77186394 | ||
| Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals | Q77704341 | ||
| Insulin B-chain reactive CD4+ regulatory T-cells induced by oral insulin treatment protect from type 1 diabetes by blocking the cytokine secretion and pancreatic infiltration of diabetogenic effector T-cells | Q78238816 | ||
| Transfer of diabetes from prediabetic NOD mice to NOD-SCID/SCID mice: association with pancreatic insulin content | Q81547586 | ||
| Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus | Q24523073 | ||
| B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes | Q28143530 | ||
| Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2. | Q33781976 | ||
| Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice | Q33950195 | ||
| Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo | Q34277742 | ||
| Adeno-associated virus (AAV) as a vehicle for therapeutic gene delivery: improvements in vector design and viral production enhance potential to prolong graft survival in pancreatic islet cell transplantation for the reversal of type 1 diabetes | Q34567050 | ||
| Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice | Q34904815 | ||
| The role of regulatory T cell defects in type I diabetes and the potential of these cells for therapy | Q35569913 | ||
| Immune modulation for prevention of type 1 diabetes mellitus | Q36056152 | ||
| A comprehensive review of interventions in the NOD mouse and implications for translation | Q36235741 | ||
| Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice | Q36361909 | ||
| Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice | Q36367339 | ||
| Long-term abrogation of autoimmune diabetes in nonobese diabetic mice by immunotherapy with anti-lymphocyte serum | Q36954517 | ||
| Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice | Q37359669 | ||
| Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity | Q39686097 | ||
| A single treatment with IL-4 via retrovirally transduced lymphocytes partially protects against diabetes in BioBreeding (BB) rats. | Q40732871 | ||
| Prevention of autoimmune insulitis by delivery of interleukin-4 plasmid using a soluble and biodegradable polymeric carrier | Q40740182 | ||
| Endogenous expression levels of autoantigens influence success or failure of DNA immunizations to prevent type 1 diabetes: addition of IL-4 increases safety | Q40761236 | ||
| Regulatory Th2-type T cell lines against insulin and GAD peptides derived from orally- and nasally-treated NOD mice suppress diabetes | Q40953893 | ||
| Combined administration of plasmids encoding IL-4 and IL-10 prevents the development of autoimmune diabetes in nonobese diabetic mice | Q43760892 | ||
| Imaging secretory vesicles by fluorescent protein insertion in propeptide rather than mature secreted peptide | Q44016473 | ||
| Protection of islets by in situ peptide-mediated transduction of the Ikappa B kinase inhibitor Nemo-binding domain peptide. | Q44276037 | ||
| The insulin secretory granule is the major site of K(ATP) channels of the endocrine pancreas | Q44328979 | ||
| Interleukin-4-expressing plasmid DNA inhibits reovirus type-2-triggered autoimmune insulitis in DBA/1 J suckling mice | Q44474592 | ||
| Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes. | Q45418435 | ||
| Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors | Q45738268 | ||
| Efficient gene delivery to human and rodent islets with double-stranded (ds) AAV-based vectors | Q45883118 | ||
| Efficient gene transfer to pancreatic islets mediated by adenoviral vectors. | Q46024273 | ||
| Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice | Q46345979 | ||
| TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes | Q47667692 | ||
| Characterization of the two nonallelic genes encoding mouse preproinsulin | Q48370767 | ||
| Specific dynamic and noninvasive labeling of pancreatic beta cells in reporter mice. | Q50748084 | ||
| Short administration of polyclonal anti-T cell antibody (ALS) in NOD mice with extensive insulitis prevents subsequent development of autoimmune diabetes. | Q51804194 | ||
| Adenoviral-mediated gene transfer to pancreatic islets does not alter islet function. | Q54635991 | ||
| Dendritic Cells Transduced to Express Interleukin-4 Prevent Diabetes in Nonobese Diabetic Mice with Advanced Insulitis | Q62748513 | ||
| Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis | Q64378678 | ||
| Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4 | Q64380123 | ||
| Pancreatic IL-4 expression results in islet-reactive Th2 cells that inhibit diabetogenic lymphocytes in the nonobese diabetic mouse. | Q64985920 | ||
| P433 | issue | 8 | |
| P304 | page(s) | 1409-1416 | |
| P577 | publication date | 2008-06-17 | |
| P1433 | published in | Molecular Therapy | Q15762400 |
| P1476 | title | AAV8-mediated gene transfer of interleukin-4 to endogenous beta-cells prevents the onset of diabetes in NOD mice | |
| P478 | volume | 16 |
| Q37624228 | A novel gene delivery method transduces porcine pancreatic duct epithelial cells. |
| Q35222861 | A practical guide to genetic engineering of pancreatic β-cells in vivo: getting a grip on RIP and MIP. |
| Q34299556 | AAV2-mediated combined subretinal delivery of IFN-α and IL-4 reduces the severity of experimental autoimmune uveoretinitis |
| Q34735468 | Adeno-associated virus-mediated IL-10 gene transfer suppresses lacrimal gland immunopathology in a rabbit model of autoimmune dacryoadenitis |
| Q90413209 | Cytokines in type 1 diabetes: mechanisms of action and immunotherapeutic targets |
| Q33649618 | Dendritic cells transduced to express interleukin 4 reduce diabetes onset in both normoglycemic and prediabetic nonobese diabetic mice |
| Q37855088 | Diabetes mellitus, a microRNA-related disease? |
| Q39178441 | Differential effects of interleukin-13 and interleukin-6 on Jak/STAT signaling and cell viability in pancreatic β-cells |
| Q43253089 | DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetes |
| Q38449217 | Expression of IL-2 in β cells by AAV8 gene transfer in pre-diabetic NOD mice prevents diabetes through activation of FoxP3-positive regulatory T cells |
| Q34706913 | Genetic vaccination for re-establishing T-cell tolerance in type 1 diabetes |
| Q34668056 | In vitro evaluation of a double-stranded self-complementary adeno-associated virus type2 vector in bone marrow stromal cells for bone healing |
| Q38732966 | Inflammation Improves Glucose Homeostasis through IKKβ-XBP1s Interaction |
| Q45872912 | In Vivo Transgene Expression in the Pancreas by the Intraductal Injection of Naked Plasmid DNA. |
| Q36824703 | Protective role of adenovirus vector-mediated interleukin-10 gene therapy on endogenous islet β-cells in recent-onset type 1 diabetes in NOD mice |
| Q38076055 | RNA interference--a silent but an efficient therapeutic tool |
| Q37913508 | Reprogramming gut and pancreas endocrine cells to treat diabetes. |
| Q37994917 | Restoring insulin production for type 1 diabetes. |
| Q47551580 | Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice |
| Q26822824 | The impact of anti-inflammatory cytokines on the pancreatic β-cell |
| Q45875053 | dsAAV8-mediated gene transfer and β-cell expression of IL-4 and β-cell growth factors are capable of reversing early-onset diabetes in NOD mice |
| Q37251067 | β-cell-specific IL-2 therapy increases islet Foxp3+Treg and suppresses type 1 diabetes in NOD mice |
| Q38730525 | β-cell-specific IL-35 therapy suppresses ongoing autoimmune diabetes in NOD mice |
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