Sublingual immunotherapy of allergic diseases

scientific article published on September 2006

Sublingual immunotherapy of allergic diseases is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1517/17425247.3.5.599
P698PubMed publication ID16948556

P2093author name stringKlaus J Erb
Frank Kalkbrenner
Melanie Werner-Klein
P2860cites workSafety and tolerability of ultra-Rush (20 minutes) sublingual immunotherapy in patients with allergic rhinitis and/or asthmaQ57629036
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Sublingual immunotherapy.Q54105175
Cytokine and Antibody Responses in Birch-Pollen-Allergic Patients Treated with Genetically Modified Derivatives of the Major Birch Pollen Allergen Bet v 1Q56827917
Specific immunotherapy prevents increased levels of allergen-specific IL-4- and IL-13-producing cells during pollen seasonQ56827955
PROPHYLACTIC INOCULATION AGAINST HAY FEVERQ57255078
Allergen-specific nasal IgG antibodies induced by vaccination with genetically modified allergens are associated with reduced nasal allergen sensitivityQ57267001
In vitro allergen-induced mRNA expression of signaling lymphocytic activation molecule by PBMC of patients with allergic rhinitis is increased during specific pollen immunotherapyQ28189640
Sublingual immunotherapy in asthma and rhinoconjunctivitis; systematic review of paediatric literatureQ33204109
Specific immunotherapy in asthmaQ33757879
Long-term clinical efficacy of grass-pollen immunotherapyQ33870492
Safety of sublingual-swallow immunotherapy in children and adultsQ33870761
Novel therapy for asthmaQ34074657
Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses.Q34170327
Analyzing meta-analyses of specific immunotherapy in the treatment of asthmaQ34321321
Appropriate and inappropriate use of immunotherapyQ34321339
Allergic rhinitis and its impact on asthmaQ34438438
Immune mechanisms of allergen-specific sublingual immunotherapyQ34484071
IgE antibody measurements in ragweed hay fever. Relationship to clinical severity and the results of immunotherapyQ34499562
In vivo instruction of suppressor commitment in naive T cellsQ34548023
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T-cell tolerance in allergic response.Q34778048
Noninjection routes for immunotherapyQ35087289
Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugsQ35178388
Renaissance of the blocking antibody concept in type I allergyQ35557996
Is sublingual immunotherapy clinically effective?Q35643305
Mechanisms of immunotherapy.Q35811876
Activated CD4+CD25+ T cells selectively kill B lymphocytesQ35848308
Efficacy and safety of sublingual immunotherapyQ35849524
Sublingual immunotherapy for allergic rhinitis: systematic review and meta-analysisQ35970094
Comparison of the clinical efficacy and safety of subcutaneous and sublingual immunotherapy: methodological approaches and experimental resultsQ36004400
Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma.Q36073821
The safety of sublingual-swallow immunotherapy: an analysis of published studiesQ36130311
The role of adjuvants in the development of mucosal vaccinesQ36194084
CD28/CTLA-4--CD80/CD86 and ICOS--B7RP-1 costimulatory pathway in bronchial asthmaQ36346464
Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cellsQ36354420
Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophagesQ36361336
Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned mediumQ36362334
Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individualsQ36362607
The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic modelQ36365507
Sublingual immunotherapy in the treatment of childrenQ36515380
Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six-year follow-up studyQ39581669
Twelve-year follow-up after discontinuation of preseasonal grass pollen immunotherapy in childhoodQ40488834
Immunotherapy safety: a prospective multi-centric monitoring study of biologically standardized therapeutic vaccines for allergic diseasesQ40517747
Coseasonal sublingual immunotherapy reduces the development of asthma in children with allergic rhinoconjunctivitisQ40523833
Clinical efficacy of sublingual and subcutaneous birch pollen allergen-specific immunotherapy: a randomized, placebo-controlled, double-blind, double-dummy studyQ40544021
Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study).Q40588482
Grass pollen immunotherapy inhibits seasonal increases in basophils and eosinophils in the nasal epithelium.Q40593688
Grass pollen immunotherapy: symptomatic improvement correlates with reductions in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season.Q40601643
Grass pollen immunotherapy decreases the number of mast cells in the skin.Q40631611
Impaired secretion of interleukin-4 and interleukin-13 by allergen-specific T cells correlates with defective nuclear expression of NF-AT2 and jun B: relevance to immunotherapyQ40637631
Increases in IL-12 messenger RNA+ cells accompany inhibition of allergen-induced late skin responses after successful grass pollen immunotherapy.Q40656273
Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma.Q40668250
A double-blind, placebo-controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extractQ40701091
Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T-cell clones specific for Phl p 1, a major grass pollen allergenQ41022355
Nasal mucosal hyperpermeability to macromolecules in atopic rhinitis and extrinsic asthmaQ41068413
Sublingual immunotherapy in tree pollen allergy. Double-blind, placebo-controlled study with a biologically standardised extract of three pollens (alder, birch and hazel) administered by a rush scheduleQ42662221
Immunotherapy decreases antigen-induced eosinophil cell migration into the nasal cavityQ43561164
Elevated secretion of myeloperoxidase by neutrophils from asthmatic patients: the effect of immunotherapy.Q43570354
Efficacy of sublingual immunotherapy in children with asthma and rhinitis: a double-blind, placebo-controlled studyQ43646876
Sublingual tryptase and ECP in children treated with grass pollen sublingual immunotherapy (SLIT): safety and immunologic implications.Q43795644
Peptidase activity on the surface of the porcine buccal mucosaQ43919783
Impact of sublingual immunotherapy on specific antibody levels in asthmatic children allergic to house dust mitesQ44290592
IL‐10 and TGF‐β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapyQ44429951
Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy.Q44467274
Effects on inflammation parameters of a double-blind, placebo controlled one-year course of SLIT in children monosensitized to mitesQ44488880
Monitoring of seasonal variability in bronchial hyper-responsiveness and sputum cell counts in non-asthmatic subjects with rhinitis and effect of specific immunotherapyQ44512048
Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies.Q44574133
Double-blind, placebo-controlled rush immunotherapy with a standardized Alternaria extractQ44773540
Induction of T 'regulatory' cells by standardized house dust mite immunotherapy: an increase in CD4+ CD25+ interleukin-10+ T cells expressing peripheral tissue trafficking markersQ45009815
Effect of immunotherapy on asthma progression, BHR and sputum eosinophils in allergic rhinitisQ45088215
Immunostimulatory sequence DNA linked to the Amb a 1 allergen promotes T(H)1 cytokine expression while downregulating T(H)2 cytokine expression in PBMCs from human patients with ragweed allergy.Q45949848
A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination.Q46469365
Specific immunotherapy with SQ standardized grass allergen tablets in asthmatics with rhinoconjunctivitisQ46892026
Selective immune redirection in humans with ragweed allergy by injecting Amb a 1 linked to immunostimulatory DNA.Q47315232
Langerhans cells from human oral epithelium are more effective at stimulating allogeneic T cells in vitro than Langerhans cells from skinQ47594341
Double-blind, placebo-controlled evaluation of sublingual immunotherapy with standardized olive pollen extract in pediatric patients with allergic rhinoconjunctivitis and mild asthma due to olive pollen sensitizationQ47702181
Pharmacokinetics of Der p 2 allergen and derived monomeric allergoid in allergic volunteersQ47715881
Pharmacokinetics of radiolabelled Par j 1 administered intranasally to allergic and healthy subjectsQ47766233
Post-marketing survey on the safety of sublingual immunotherapy in children below the age of 5 yearsQ47795423
Safety of sublingual immunotherapy with a monomeric allergoid in very young children.Q47886315
Clinical efficacy of sublingual-swallow immunotherapy: a double-blind, placebo-controlled trial of a standardized five-grass-pollen extract in rhinitisQ47938843
A double-blind, placebo-controlled birch allergy vaccination study: inhibition of CD23-mediated serum-immunoglobulin E-facilitated allergen presentationQ47988492
Bacillus Calmette-Guérin-induced interleukin-12 did not additionally improve clinical and immunologic parameters in asthmatic children treated with sublingual immunotherapyQ47988526
Immunotherapy with a standardized Dermatophagoides pteronyssinus extract. VI. Specific immunotherapy prevents the onset of new sensitizations in children.Q50621222
Long-lasting effect of sublingual immunotherapy in children with asthma due to house dust mite: a 10-year prospective study.Q51686636
Grass pollen sublingual immunotherapy for seasonal rhinoconjunctivitis: a randomized controlled trial.Q51719532
Grass pollen immunotherapy for hayfever is associated with increases in local nasal but not peripheral Th1:Th2 cytokine ratios.Q51727137
Insect venom immunotherapy induces interleukin-10 production and a Th2-to-Th1 shift, and changes surface marker expression in venom-allergic subjects.Q52553246
Requirement of CD28-CD86 costimulation for allergen-specific T cell proliferation and cytokine expression.Q52904932
Lack of detectable alterations in immune responses during sublingual immunotherapy in children with seasonal allergic rhinoconjunctivitis to grass pollen.Q52940754
A prospective, randomized, double-blind, placebo-controlled multi-centre study on the efficacy and safety of sublingual immunotherapy (SLIT) in children with seasonal allergic rhinoconjunctivitis to grass pollen.Q52942005
Economic evaluation of specific immunotherapy versus symptomatic treatment of allergic rhinitis in Germany.Q52972998
Sublingual-swallow immunotherapy (SLIT) in patients with asthma due to house-dust mites: a double-blind, placebo-controlled study.Q53551598
Characterization of dendritic cells from human oral mucosa: a new Langerhans' cell type with high constitutive FcepsilonRI expression.Q53697543
Sublingual immunotherapy: a double-blind, placebo-controlled trial with Parietaria judaica extract standardized in mass units in patients with rhinoconjunctivitis, asthma, or both.Q53729251
Early effect of ultrarush venom immunotherapy on the IgG antibody response.Q53796451
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectimmunotherapyQ1427096
P304page(s)599-612
P577publication date2006-09-01
P1433published inExpert Opinion on Drug DeliveryQ5421203
P1476titleSublingual immunotherapy of allergic diseases
P478volume3