Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies.

scientific article published in September 2003

Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1046/J.1365-2222.2003.01699.X
P698PubMed publication ID12956739

P50authorPeter ValentQ56697676
P2093author name stringD Kraft
R Valenta
W R Sperr
H Semper
V Niederberger
N Mothes
M Heinzkill
K J Drachenberg
M T Krauth
Y Majlesi
P2860cites workA human monoclonal IgE antibody defines a highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5: molecular, immunological, and structural characterization of the epitope-containing domain.Q31815273
Immunological mechanisms operative in allergen-specific immunotherapyQ33643137
The Th1/Th2 paradigmQ34429440
Safety, immunogenicity, and efficacy of Plasmodium falciparum repeatless circumsporozoite protein vaccine encapsulated in liposomesQ40933066
A well-tolerated grass pollen-specific allergy vaccine containing a novel adjuvant, monophosphoryl lipid A, reduces allergic symptoms after only four preseasonal injectionsQ43650387
A Th1-inducing adjuvant, MPL, enhances antibody profiles in experimental animals suggesting it has the potential to improve the efficacy of allergy vaccines.Q43812891
Molecular characterization of human IgG monoclonal antibodies specific for the major birch pollen allergen Bet v 1. Anti-allergen IgG can enhance the anaphylactic reaction.Q47895314
PROPHYLACTIC INOCULATION AGAINST HAY FEVERQ57255078
Polarized TH1 responses by liposome-entrapped allergen and its potential in immunotherapy of allergic disordersQ74452718
Safety and immunogenicity of a hepatitis B vaccine formulated with a novel adjuvant systemQ74486539
Allergenic activity of a major grass pollen allergen is elevated in the presence of nasal secretionQ74490053
P433issue9
P921main subjectantibodyQ79460
vaccineQ134808
immunotherapyQ1427096
P304page(s)1198-1208
P577publication date2003-09-01
P1433published inClinical & Experimental AllergyQ5133747
P1476titleAllergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies
P478volume33

Reverse relations

cites work (P2860)
Q37625474A B Cell Epitope Peptide Derived from the Major Grass Pollen Allergen Phl p 1 Boosts Allergen-Specific Secondary Antibody Responses without Allergen-Specific T Cell Help
Q42713288A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro
Q39343215A hybrid expressing genetically engineered major allergens of the Parietaria pollen as a tool for specific allergy vaccination
Q88964571A lipid A-based TLR4 mimetic effectively adjuvants a Yersinia pestis rF-V1 subunit vaccine in a murine challenge model
Q53006587A novel adjuvant complex, tyrosine-MPL, for prophylactic and therapeutic vaccines.
Q30768718A novel adjuvant-allergen complex, CBP-rFel d 1, induces up-regulation of CD86 expression and enhances cytokine release by human dendritic cells in vitro.
Q52846388A preventive immunization approach against insect bite hypersensitivity: Intralymphatic injection with recombinant allergens in Alum or Alum and monophosphoryl lipid A.
Q80156066A synthetic triacylated pseudo-dipeptide molecule promotes Th1/TReg immune responses and enhances tolerance induction via the sublingual route
Q46879563Absence of systemic immunologic changes during dose build-up phase and early maintenance period in effective specific sublingual immunotherapy in children
Q39151158Adjuvants for allergy immunotherapeutics.
Q38055323Adjuvants for allergy vaccines
Q57297464Allergen Extracts for In Vivo Diagnosis and Treatment of Allergy: Is There a Future?
Q90181979Allergen Immunotherapy-Induced Immunoglobulin G4 Reduces Basophil Activation in House Dust Mite-Allergic Asthma Patients
Q36864947Allergen immunotherapy for allergic respiratory diseases
Q61814280Allergen-Specific Antibodies Regulate Secondary Allergen-Specific Immune Responses
Q37166041Allergen-specific IgG antibodies purified from mite-allergic patients sera block the IgE recognition of Dermatophagoides pteronyssinus antigens: an in vitro study
Q40006542Allergen-specific immunotherapy of allergy and asthma: current and future trends
Q38013789Allergen-specific immunotherapy: from therapeutic vaccines to prophylactic approaches.
Q36395501Allergy testing: the role of recombinant allergens
Q35873779Allergy vaccines--new approaches to an old concept
Q37625553An immunological overview of allergen specific immunotherapy -- subcutaneous and sublingual routes
Q51978305Antigens drive memory IgE responses in human allergy via the nasal mucosa.
Q35850656Biology of tree pollen allergens
Q52785931Candidin and trichophytin stimulate the production of Th1 and regulatory cytokines by peripheral blood mononuclear cells: implication for their use as adjuvants in immunotherapy.
Q39321330Carbohydrate-based particles reduce allergic inflammation in a mouse model for cat allergy.
Q37822834Clinical immunology review series: an approach to desensitization
Q42631175Clinical improvement and immunological changes in atopic dermatitis patients undergoing subcutaneous immunotherapy with a house dust mite allergoid: a pilot study.
Q38761412Clinical use of adjuvants in allergen-immunotherapy.
Q52767099Comparison of the immunogenicity of BM32, a recombinant hypoallergenic B cell epitope-based grass pollen allergy vaccine with allergen extract-based vaccines.
Q56827917Cytokine and Antibody Responses in Birch-Pollen-Allergic Patients Treated with Genetically Modified Derivatives of the Major Birch Pollen Allergen Bet v 1
Q36302500Determinants of efficacy and safety in epicutaneous allergen immunotherapy: summary of three clinical trials
Q35566610Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy.
Q88289109Dust mite allergen-specific immunotherapy increases IL4 DNA methylation and induces Der p-specific T cell tolerance in children with allergic asthma
Q33733105Effect of activation of Toll-like receptor 7 in the inhibition of allergic asthma on a mouse model
Q35113146Effects of nasal corticosteroids on boosts of systemic allergen-specific IgE production induced by nasal allergen exposure
Q34051852Egg-white-specific IgA and IgA2 antibodies in egg-allergic children: is there a role in tolerance induction?
Q42578489Epicutaneous Immunotherapy for Aeroallergen and Food Allergy
Q34166561Epigenetic modifications and improved regulatory T-cell function in subjects undergoing dual sublingual immunotherapy
Q92701792Exopolysaccharide Produced by Lactobacillus paracasei IJH-SONE68 Prevents and Improves the Picryl Chloride-Induced Contact Dermatitis
Q39329667Expression of recombinant Ara h 6 in Pichia pastoris but not in Escherichia coli preserves allergic effector function and allows assessment of specific mutations.
Q37900649Factors influencing the allergenicity and adjuvanticity of allergens.
Q51042780Fast onset of action of sublingual immunotherapy in house dust mite-induced allergic rhinitis: a multicenter, randomized, double-blind, placebo-controlled trial.
Q58617547Flow-assisted quantification of in vitro activated basophils in the diagnosis of wasp venom allergy and follow-up of wasp venom immunotherapy
Q36549691Generation of hypoallergenic neoglycoconjugates for dendritic cell targeted vaccination: a novel tool for specific immunotherapy
Q37479670How safe are the biologicals in treating asthma and rhinitis?
Q28482224Identification of critical amino acids in an immunodominant IgE epitope of Pen c 13, a major allergen from Penicillium citrinum
Q50760318IgE+ B cells are scarce, but allergen-specific B cells with a memory phenotype circulate in patients with allergic rhinitis.
Q36545702IgE-mediated allergen presentation and blocking antibodies: regulation of T-cell activation in allergy
Q33770788IgG antibodies produced during subcutaneous allergen immunotherapy mediate inhibition of basophil activation via a mechanism involving both FcgammaRIIA and FcgammaRIIB.
Q34484071Immune mechanisms of allergen-specific sublingual immunotherapy
Q38181015Immunobiology of critical pediatric asthma
Q38994739Immunoglobulin Glycosylation Effects in Allergy and Immunity
Q28265326Immunological mechanisms of allergen-specific immunotherapy
Q38352179Immunotherapy in all aspects
Q35671703Immunotherapy of allergic disease
Q73903596Induction of 'blocking' IgG antibodies during immunotherapy
Q46961929Inhibition of rBet v 1-induced basophil histamine release with specific immunotherapy -induced serum immunoglobulin G: no evidence that FcgammaRIIB signalling is important
Q40263989Inhibition of type I allergic responses with nanogram doses of replicon-based DNA vaccines.
Q52324318Innate Immune Responses in Leprosy.
Q41156645MPLA shows attenuated pro-inflammatory properties and diminished capacity to activate mast cells in comparison with LPS.
Q37502904Mechanisms of sublingual immunotherapy
Q37958561Mechanisms underlying allergy vaccination with recombinant hypoallergenic allergen derivatives
Q37309704Mechanisms, safety and efficacy of a B cell epitope-based vaccine for immunotherapy of grass pollen allergy
Q52625055Microcrystalline Tyrosine and Aluminum as Adjuvants in Allergen-Specific Immunotherapy Protect from IgE-Mediated Reactivity in Mouse Models and Act Independently of Inflammasome and TLR Signaling.
Q36383819Molecular approaches for new vaccines against allergy
Q35558343Molecular evolution of hypoallergenic hybrid proteins for vaccination against grass pollen allergy.
Q26743503Monitoring Allergen Immunotherapy Effects by Microarray
Q40511372Monophosphoryl lipid A (MPL) promotes allergen-induced immune deviation in favour of Th1 responses.
Q33846653Nature of regulatory T cells in the context of allergic disease
Q26824787New strategies for allergen T cell epitope identification: going beyond IgE
Q47884083Next generation immunotherapy for tree pollen allergies
Q55436442Next-Generation of Allergen-Specific Immunotherapies: Molecular Approaches.
Q45102968Non-anaphylactic surface-exposed peptides of the major birch pollen allergen, Bet v 1, for preventive vaccination.
Q39103046Novel approaches and perspectives in allergen immunotherapy
Q36901292Novel birch pollen specific immunotherapy formulation based on contiguous overlapping peptides
Q37439440Optimized subunit vaccine protects against experimental leishmaniasis
Q36689005Pollinex Quattro: a novel and well-tolerated, ultra short-course allergy vaccine
Q44240760Pollinex Quattro: an innovative four injections immunotherapy in allergic rhinitis
Q42772049Possible therapeutic potential of a recombinant group 2 grass pollen allergen-specific antibody fragment.
Q98177685Preventive Allergen-Specific Vaccination Against Allergy: Mission Possible?
Q79307565Production of interleukin-12 by monocytes and interferon-gamma by natural killer cells in allergic patients during rush immunotherapy
Q34430399Prophylactic and therapeutic vaccination with carrier-bound Bet v 1 peptides lacking allergen-specific T cell epitopes reduces Bet v 1-specific T cell responses via blocking antibodies in a murine model for birch pollen allergy.
Q39366990Rational design of hypoallergens applied to the major cat allergen Fel d 1.
Q37847222Recombinant allergens for allergen-specific immunotherapy: 10 years anniversary of immunotherapy with recombinant allergens
Q39284149Recombinant allergy vaccines based on allergen-derived B cell epitopes.
Q34361546Recombinant house dust mite allergens.
Q38366518Review: The role of antibodies, autoantigens and food allergens in canine atopic dermatitis.
Q47649812Safety and efficacy of immunotherapy with the recombinant B-cell epitope-based grass pollen vaccine BM32.
Q40790855Specific allergen immunotherapy: effect on IgE, IgG4 and chemokines in patients with allergic rhinitis
Q91218696Strong dose response after immunotherapy with PQ grass using conjunctival provocation testing
Q34787526Structural and immunologic cross-reactivity among filarial and mite tropomyosin: implications for the hygiene hypothesis
Q55527154Sub-lingual immunotherapy: world allergy organization position paper 2009.
Q48273752Subcutaneous immunotherapy with purified Der p1 and 2 suppresses type 2 immunity in a murine asthma model
Q37888684Subcutaneous versus sublingual immunotherapy for allergic rhinitis and/or asthma
Q36583727Sublingual immunotherapy of allergic diseases
Q35842681Taking a Toll on human disease: Toll-like receptor 4 agonists as vaccine adjuvants and monotherapeutic agents
Q45417025The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease.
Q51581569The clinical significance of food specific IgE/IgG4 in food specific atopic dermatitis.
Q26801862The expanding role of immunopharmacology: IUPHAR Review 16
Q37502385The influence of antigen targeting to sub-cellular compartments on the anti-allergic potential of a DNA vaccine
Q35146543The role of casein-specific IgA and TGF-β in children with food protein-induced enterocolitis syndrome to milk
Q35824051Therapeutics targeting the innate immune system
Q43988658Tolerogenic T cells, Th1/Th17 cytokines and TLR2/TLR4 expressing dendritic cells predominate the microenvironment within distinct oral mucosal sites
Q35975564Transition from a botanical to a molecular classification in tree pollen allergy: implications for diagnosis and therapy
Q83892585Ultra-short-course seasonal allergy vaccine (Pollinex Quattro)
Q26768511Vaccine development for allergen-specific immunotherapy based on recombinant allergens and synthetic allergen peptides: Lessons from the past and novel mechanisms of action for the future
Q81453794[Immunologic control parameters during specific immunotherapy]

Search more.