Next-Generation of Allergen-Specific Immunotherapies: Molecular Approaches.

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Next-Generation of Allergen-Specific Immunotherapies: Molecular Approaches. is …
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review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1104496271
P356DOI10.1007/S11882-018-0790-X
P932PMC publication ID5994214
P698PubMed publication ID29886521

P50authorAlexander KaraulovQ4214390
Leyla Namazova-BaranovaQ29359263
Musa KhaitovQ30345117
P2093author name stringRudolf Valenta
Raffaela Campana
Victoria Garib
Mirela Curin
P2860cites workTreating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement.Q55277398
Intralymphatic immunotherapy for cat allergy induces tolerance after only 3 injectionsQ57266970
Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivativesQ57266980
Non–IgE-mediated chronic allergic skin inflammation revealed with rBet v 1 fragmentsQ57920411
Standardization of allergen products: 1. Detailed characterization of GMP-produced recombinant Bet v 1.0101 as biological reference preparationQ58490825
Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodiesQ60312277
Skin test evaluation of a novel peptide carrier-based vaccine, BM32, in grass pollen-allergic patients.Q64910571
Abrogation of reaginic antibodies with modified allergensQ67589527
[Therapy of atopic dermatitis in children. Study on the use of a desensitizing preparation]Q68997663
[Comparative evaluation of the effectiveness of different methods of prophylactic treatment for children with bronchial asthma]Q69383937
Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunizationQ71046576
Treatment of cat allergy with T-cell reactive peptidesQ71906922
Fel d 1 peptides: effect on skin tests and cytokine synthesis in cat-allergic human subjectsQ71943164
Complex histaglobin and allergoid therapy of seasonal allergic diseases of the upper respiratory tractQ72699779
Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen Bet v 1Q74394674
The latex allergen Hev b 5 transcript is widely distributed after subcutaneous injection in BALB/c mice of its DNA vaccineQ77398129
Blocking antibodies induced by specific allergy vaccination prevent the activation of CD4+ T cells by inhibiting serum-IgE-facilitated allergen presentationQ78145327
Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitisQ79189373
Allergen-specific immunotherapy with recombinant grass pollen allergensQ81207775
A hypoallergenic hybrid molecule with increased immunogenicity consisting of derivatives of the major grass pollen allergens, Phl p 2 and Phl p 6Q81641549
Side-effects of allergen-specific immunotherapy: a prospective multi-centre studyQ82654593
Developments in allergen-specific immunotherapy: from allergen extracts to allergy vaccines bypassing allergen-specific immunoglobulin E and T cell reactivityQ83153056
Studies on "allergoids" prepared from naturally occurring allergens. I. Assay of allergenicity and antigenicity of formalinized rye group I componentQ24545738
Amino acid sequence of Fel dI, the major allergen of the domestic cat: protein sequence analysis and cDNA cloning.Q24560053
Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunizationQ24599495
Vaccine development for allergen-specific immunotherapy based on recombinant allergens and synthetic allergen peptides: Lessons from the past and novel mechanisms of action for the futureQ26768511
Development and evaluation of a sublingual tablet based on recombinant Bet v 1 in birch pollen-allergic patientsQ27700098
Immunological mechanisms of allergen-specific immunotherapyQ28265326
Allergen immunotherapy for allergic asthma: a systematic review and meta-analysisQ30234365
Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypesQ30238498
Peripheral T-cell tolerance induced in naive and primed mice by subcutaneous injection of peptides from the major cat allergen Fel d IQ30454050
Conversion of grass pollen allergen-specific human IgE into a protective IgG(1) antibodyQ31107578
Genetically engineered and synthetic allergen derivatives: candidates for vaccination against type I allergyQ33737248
Long-term clinical efficacy of grass-pollen immunotherapyQ33870492
Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year follow-up on the PAT studyQ34005065
A nonallergenic birch pollen allergy vaccine consisting of hepatitis PreS-fused Bet v 1 peptides focuses blocking IgG toward IgE epitopes and shifts immune responses to a tolerogenic and Th1 phenotypeQ34106036
Tolerization of a type I allergic immune response through transplantation of genetically modified hematopoietic stem cellsQ34361879
Conversion of Der p 23, a new major house dust mite allergen, into a hypoallergenic vaccine.Q34415246
Prophylactic and therapeutic vaccination with carrier-bound Bet v 1 peptides lacking allergen-specific T cell epitopes reduces Bet v 1-specific T cell responses via blocking antibodies in a murine model for birch pollen allergy.Q34430399
Oral immunotherapy induces IgG antibodies that act through FcγRIIb to suppress IgE-mediated hypersensitivityQ34664144
The future of antigen-specific immunotherapy of allergyQ34716363
Renaissance of the blocking antibody concept in type I allergyQ35557996
Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy.Q35566610
Immunotherapy of allergic diseaseQ35671703
Hypoallergenic Der p 1/Der p 2 combination vaccines for immunotherapy of house dust mite allergyQ36125658
Carrier-bound nonallergenic Der p 2 peptides induce IgG antibodies blocking allergen-induced basophil activation in allergic patients.Q36125684
SEROLOGICAL EVIDENCE OF IMMUNITY WITH COEXISTING SENSITIZATION IN A TYPE OF HUMAN ALLERGY (HAY FEVER).Q36256769
Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactionsQ36367890
Isolation of an immunodominant IgE hapten from an epitope expression cDNA library. Dissection of the allergic effector reaction.Q36676514
Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1: potential use of hypoallergenic isoforms for immunotherapyQ36798594
Intralymphatic allergen administration renders specific immunotherapy faster and safer: a randomized controlled trialQ36970017
Detection of IgE Reactivity to a Handful of Allergen Molecules in Early Childhood Predicts Respiratory Allergy in AdolescenceQ47340806
Recombinant allergen and peptide-based approaches for allergy prevention by oral tolerance.Q47939182
Efficacy of 2 months of allergen-specific immunotherapy with Bet v 1-derived contiguous overlapping peptides in patients with allergic rhinoconjunctivitis: Results of a phase IIb study.Q50501197
Safety and immunogenicity of immunotherapy with Bet v 1-derived contiguous overlapping peptides.Q50850165
Generation and Evaluation of Prophylactic mRNA Vaccines Against Allergy.Q51253941
Use of A-type CpG oligodeoxynucleotides as an adjuvant in allergen-specific immunotherapy in humans: a phase I/IIa clinical trial.Q51813678
Combination of passive and active immunization in honeybee venom immunotherapy.Q52463282
Comparison of the immunogenicity of BM32, a recombinant hypoallergenic B cell epitope-based grass pollen allergy vaccine with allergen extract-based vaccines.Q52767099
Oral gene delivery with chitosan--DNA nanoparticles generates immunologic protection in a murine model of peanut allergy.Q52844746
Immunize and disappear-safety-optimized mRNA vaccination with a panel of 29 allergens.Q53059448
Establishment of recombinant major allergens Bet v 1 and Phl p 5a as Ph. Eur. reference standards and validation of ELISA methods for their measurement. Results from feasibility studies.Q53117473
Development of a hypoallergenic recombinant parvalbumin for first-in-man subcutaneous immunotherapy of fish allergy.Q53581091
Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis.Q53988360
A hypoallergenic cat vaccine based on Fel d 1-derived peptides fused to hepatitis B PreS.Q54365271
Cell Therapy for Prophylactic Tolerance in Immunoglobulin E-mediated AllergyQ37008459
Immunotherapy With the PreS-based Grass Pollen Allergy Vaccine BM32 Induces Antibody Responses Protecting Against Hepatitis B InfectionQ37309327
Mechanisms, safety and efficacy of a B cell epitope-based vaccine for immunotherapy of grass pollen allergyQ37309704
Vaccination with genetically engineered allergens prevents progression of allergic disease.Q37569798
From allergen genes to allergy vaccinesQ37700719
Recombinant allergens for allergen-specific immunotherapy: 10 years anniversary of immunotherapy with recombinant allergensQ37847222
Cell-based therapy in allergyQ37877641
Mechanisms underlying allergy vaccination with recombinant hypoallergenic allergen derivativesQ37958561
Allergen-specific immunotherapy: from therapeutic vaccines to prophylactic approaches.Q38013789
International consensus on allergy immunotherapy.Q38544969
Windows of opportunity for tolerance induction for allergy by studying the evolution of allergic sensitization in birth cohortsQ38633435
Safety and long-term immunological effects of CryJ2-LAMP plasmid vaccine in Japanese red cedar atopic subjects: A phase I studyQ38729999
Evolution and predictive value of IgE responses toward a comprehensive panel of house dust mite allergens during the first 2 decades of lifeQ38802935
Allergic Rhinitis: Mechanisms and TreatmentQ38809265
Specific allergen immunotherapy for the treatment of atopic eczema: a Cochrane systematic reviewQ38835526
Early childhood IgE reactivity to pathogenesis-related class 10 proteins predicts allergic rhinitis in adolescenceQ39070333
Recombinant allergy vaccines based on allergen-derived B cell epitopes.Q39284149
Rational design of hypoallergens applied to the major cat allergen Fel d 1.Q39366990
Effect of ragweed hyperimmune human gamma globulin on in vivo and in vitro parameters of ragweed sensitivityQ39375831
Effects of passive antibody in bee venom anaphylaxisQ39475985
Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: candidates for a novel form of specific immunotherapyQ39782156
Development and preliminary clinical evaluation of a peptide immunotherapy vaccine for cat allergy.Q39796254
Risk factors for fatal and nonfatal reactions to subcutaneous immunotherapy: National surveillance study on allergen immunotherapy (2008-2013).Q39944021
Sensitization to cat and dog allergen molecules in childhood and prediction of symptoms of cat and dog allergy in adolescence: A BAMSE/MeDALL studyQ40190132
Molecular spreading and predictive value of preclinical IgE response to Phleum pratense in children with hay feverQ40279334
Prediction of peanut allergy in adolescence by early childhood storage protein-specific IgE signatures: The BAMSE population-based birth cohortQ40338480
Immunotherapy with T‐cell‐reactive peptides derived from allergensQ40392723
Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study).Q40588482
Studies on allergoids from naturally occurring allergens. IV. Efficacy and safety of long-term allergoid treatment of ragweed hay feverQ40849553
Evolution pathways of IgE responses to grass and mite allergens throughout childhoodQ40951587
Prophylaxis of summer hay-fever and asthma: a controlled trial comparing crude grass-pollen extracts with the isolated main protein componentQ41034495
The safety and efficacy of ALLERVAX CAT in cat allergic patientsQ41708614
Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicityQ41745934
Displaying Fel d1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergyQ41895016
Hypoallergenic derivatives of Fel d 1 obtained by rational reassembly for allergy vaccination and tolerance induction.Q42143464
Development of an Allergy Immunotherapy Leads to a New Type of Hepatitis B VaccineQ42387623
Allergy immunotherapy with a hypoallergenic recombinant birch pollen allergen rBet v 1-FV in a randomized controlled trialQ42789553
Carrier-bound, nonallergenic Ole e 1 peptides for vaccination against olive pollen allergyQ43603745
Nonanaphylactic synthetic peptides derived from B cell epitopes of the major grass pollen allergen, Phl p 1, for allergy vaccination.Q43711891
Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies.Q44574133
Non-anaphylactic surface-exposed peptides of the major birch pollen allergen, Bet v 1, for preventive vaccination.Q45102968
Allergen-specific immunoprophylaxis: toward secondary prevention of allergic rhinitis?Q45263896
The European Union CREATE project: a model for international standardization of allergy diagnostics and vaccinesQ46398168
Fel d 1-derived peptide antigen desensitization shows a persistent treatment effect 1 year after the start of dosing: a randomized, placebo-controlled study.Q46720701
Inhibition of rBet v 1-induced basophil histamine release with specific immunotherapy -induced serum immunoglobulin G: no evidence that FcgammaRIIB signalling is importantQ46961929
Characterization of a hypoallergenic recombinant Bet v 1 variant as a candidate for allergen-specific immunotherapyQ46970160
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P433issue7
P921main subjectallergenQ186752
immunotherapyQ1427096
allergen immunotherapyQ1641412
hypersensitivityQ5958765
P304page(s)39
P577publication date2018-06-09
P1433published inCurrent Allergy and Asthma ReportsQ2246111
P1476titleNext-Generation of Allergen-Specific Immunotherapies: Molecular Approaches.
P478volume18

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cites work (P2860)
Q92955945A hypoallergenic peptide mix containing T cell epitopes of the clinically relevant house dust mite allergens
Q57297464Allergen Extracts for In Vivo Diagnosis and Treatment of Allergy: Is There a Future?
Q97681208Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy
Q90182025Dynamics Rationalize Proteolytic Susceptibility of the Major Birch Pollen Allergen Bet v 1
Q93010272Efficacy of acupuncture at three nasal acupoints plus acupoint application for perennial allergic rhinitis: A multicenter, randomized controlled trial protocol
Q90858056Expression and characterization of recombinant Par j 1 and Par j 2 resembling the allergenic epitopes of Parietaria judaica pollen
Q90423881Mechanisms of allergen-specific immunotherapy for allergic rhinitis and food allergies
Q58606564Neoepitopes: a new take on beta cell autoimmunity in type 1 diabetes
Q59802672Precision medicine allergy immunoassay methods for assessing immunoglobulin E sensitization to aeroallergen molecules
Q98177685Preventive Allergen-Specific Vaccination Against Allergy: Mission Possible?
Q91977713Recombinant allergens for immunotherapy: state of the art
Q58554575Virus-Like Particles as Carrier Systems to Enhance Immunomodulation in Allergen Immunotherapy

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