scholarly article | Q13442814 |
P50 | author | Chantell S Evans | Q86013286 |
Edwin Chapman | Q59541853 | ||
P2093 | author name string | Zhao Wang | |
R Bryan Sutton | |||
Laurie M Biela | |||
Amelia R Striegel | |||
Noreen E Reist | |||
Jillian B Delehoy | |||
P2860 | cites work | Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses | Q24671842 |
The C2 domain calcium-binding motif: structural and functional diversity | Q24674621 | ||
Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release | Q26269912 | ||
Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain? | Q26269956 | ||
Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine | Q27637071 | ||
Structure of human synaptotagmin 1 C2AB in the absence of Ca2+ reveals a novel domain association | Q27648873 | ||
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold | Q27729921 | ||
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes | Q27861039 | ||
How synaptotagmin promotes membrane fusion. | Q27863355 | ||
Mutations in the effector binding loops in the C2A and C2B domains of synaptotagmin I disrupt exocytosis in a nonadditive manner | Q73918502 | ||
Lipid binding ridge on loops 2 and 3 of the C2A domain of synaptotagmin I as revealed by NMR spectroscopy | Q77332922 | ||
Synaptotagmin I functions as a calcium regulator of release probability | Q28204147 | ||
Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis | Q28204182 | ||
Synaptotagmin-mediated bending of the target membrane is a critical step in Ca(2+)-regulated fusion | Q28584744 | ||
Position of synaptotagmin I at the membrane interface: cooperative interactions of tandem C2 domains | Q30441210 | ||
C2A activates a cryptic Ca(2+)-triggered membrane penetration activity within the C2B domain of synaptotagmin I. | Q34010567 | ||
Differential regulation of synchronous versus asynchronous neurotransmitter release by the C2 domains of synaptotagmin 1 | Q34093007 | ||
Electrostatic control of the membrane targeting of C2 domains | Q34110570 | ||
Ca2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling in vivo | Q34171564 | ||
Synaptotagmin interaction with the syntaxin/SNAP-25 dimer is mediated by an evolutionarily conserved motif and is sensitive to inositol hexakisphosphate | Q34288288 | ||
Membrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo | Q34974283 | ||
C2B polylysine motif of synaptotagmin facilitates a Ca2+-independent stage of synaptic vesicle priming in vivo. | Q35190997 | ||
SNARE proteins contribute to calcium cooperativity of synaptic transmission | Q35582307 | ||
Absence of synaptotagmin disrupts excitation-secretion coupling during synaptic transmission. | Q35871642 | ||
Membrane binding and subcellular targeting of C2 domains | Q36582982 | ||
Synaptic transmission persists in synaptotagmin mutants of Drosophila | Q38469273 | ||
Co-operative action a calcium ions in transmitter release at the neuromuscular junction | Q41528052 | ||
Ca(2+)-synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusion. | Q41791620 | ||
A quaternary SNARE-synaptotagmin-Ca2+-phospholipid complex in neurotransmitter release | Q42147793 | ||
Mutations in the second C2 domain of synaptotagmin disrupt synaptic transmission at Drosophila neuromuscular junctions | Q43645563 | ||
Synaptotagmins I and IV promote transmitter release independently of Ca(2+) binding in the C(2)A domain | Q44058592 | ||
The synaptotagmin C2A domain is part of the calcium sensor controlling fast synaptic transmission | Q44520400 | ||
A role for synaptotagmin (p65) in regulated exocytosis | Q44977634 | ||
External Ca2+ dependency of synaptic transmission in drosophila synaptotagmin I mutants | Q46630040 | ||
Drosophila synaptotagmin I null mutants survive to early adulthood | Q47072128 | ||
Calcium-dependent membrane penetration is a hallmark of the C2 domain of cytosolic phospholipase A2 whereas the C2A domain of synaptotagmin binds membranes electrostatically. | Q47828162 | ||
Synaptotagmin I stabilizes synaptic vesicles via its C(2)A polylysine motif. | Q48027351 | ||
A gain-of-function mutation in synaptotagmin-1 reveals a critical role of Ca2+-dependent soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex binding in synaptic exocytosis. | Q48352739 | ||
Synaptotagmin: a calcium sensor on the synaptic vesicle surface | Q48480063 | ||
Direct interaction of a Ca2+-binding loop of synaptotagmin with lipid bilayers | Q50524047 | ||
Synaptotagmin I functions as a calcium sensor to synchronize neurotransmitter release. | Q52009038 | ||
Ca2+ regulates the interaction between synaptotagmin and syntaxin 1. | Q52508040 | ||
Neural specificity of elav expression: defining a Drosophila promoter for directing expression to the nervous system. | Q52543806 | ||
Morphologically docked synaptic vesicles are reduced in synaptotagmin mutants of Drosophila. | Q52565810 | ||
Drosophila synaptotagmin I null mutants show severe alterations in vesicle populations but calcium-binding motif mutants do not. | Q52569216 | ||
The C(2)B Ca(2+)-binding motif of synaptotagmin is required for synaptic transmission in vivo. | Q52597582 | ||
Nerve-evoked synchronous release and high K+ -induced quantal events are regulated separately by synaptotagmin I at Drosophila neuromuscular junctions. | Q52673852 | ||
Structure/function analysis of Ca2+ binding to the C2A domain of synaptotagmin 1 | Q58191235 | ||
Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C | Q71142569 | ||
Calcium-dependent transmitter secretion from fibroblasts: modulation by synaptotagmin I | Q71712441 | ||
Kinetics of synaptotagmin responses to Ca2+ and assembly with the core SNARE complex onto membranes | Q73203897 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Synaptotagmin 1 Dmel_CG3139 | Q29812939 |
P304 | page(s) | 1253-1260 | |
P577 | publication date | 2012-01-01 | |
P1433 | published in | Journal of Neuroscience | Q1709864 |
P1476 | title | Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission | |
P478 | volume | 32 |
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Q30994945 | Analysis of shape and spatial interaction of synaptic vesicles using data from focused ion beam scanning electron microscopy (FIB-SEM). |
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Q35687725 | Calcium binding promotes conformational flexibility of the neuronal Ca(2+) sensor synaptotagmin |
Q34281080 | Calcium sensitive ring-like oligomers formed by synaptotagmin |
Q28281363 | Complexin controls spontaneous and evoked neurotransmitter release by regulating the timing and properties of synaptotagmin activity |
Q38302250 | Control of membrane gaps by synaptotagmin-Ca2+ measured with a novel membrane distance ruler |
Q21133645 | Differential roles for snapin and synaptotagmin in the synaptic vesicle cycle |
Q41836213 | Drosophila studies support a role for a presynaptic synaptotagmin mutation in a human congenital myasthenic syndrome. |
Q41987606 | Dystroglycan binding to α-neurexin competes with neurexophilin-1 and neuroligin in the brain. |
Q37013623 | Genetic analysis of synaptotagmin C2 domain specificity in regulating spontaneous and evoked neurotransmitter release |
Q57173506 | Mechanism of neurotransmitter release coming into focus |
Q41853121 | Membrane Docking of the Synaptotagmin 7 C2A Domain: Electron Paramagnetic Resonance Measurements Show Contributions from Two Membrane Binding Loops. |
Q33751347 | Neurexins. |
Q38749071 | Non-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions |
Q28831105 | Ring-like oligomers of Synaptotagmins and related C2 domain proteins |
Q38086430 | Single Ca2+ channels and exocytosis at sensory synapses |
Q64992132 | Structural basis for the clamping and Ca2+ activation of SNARE-mediated fusion by synaptotagmin. |
Q27687169 | Structural basis of allosteric interactions among Ca2+-binding sites in a K+ channel RCK domain |
Q41112044 | Synaptotagmin SYTA forms ER-plasma membrane junctions that are recruited to plasmodesmata for plant virus movement |
Q100945927 | Synaptotagmin-1 membrane binding is driven by the C2B domain and assisted cooperatively by the C2A domain |
Q47319293 | Targeting Phosphatidylserine with Calcium-Dependent Protein-Drug Conjugates for the Treatment of Cancer |
Q34462217 | The Arabidopsis synaptotagmin SYTA regulates the cell-to-cell movement of diverse plant viruses |
Q89594549 | The C2A domain of synaptotagmin is an essential component of the calcium sensor for synaptic transmission |
Q62512847 | The high-affinity calcium sensor synaptotagmin-7 serves multiple roles in regulated exocytosis |
Q36558887 | The number and organization of Ca2+ channels in the active zone shapes neurotransmitter release from Schaffer collateral synapses |
Q40736285 | The second C2-domain of copine-2, copine-6 and copine-7 is responsible for their calcium-dependent membrane association |
Q27011779 | The structure and function of 'active zone material' at synapses |
Q35594101 | The synaptotagmin juxtamembrane domain is involved in neuroexocytosis. |
Q36132208 | Transmission, Development, and Plasticity of Synapses. |
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