scholarly article | Q13442814 |
P356 | DOI | 10.1126/SCIENCE.273.5272.248 |
P698 | PubMed publication ID | 8662510 |
P50 | author | Thomas C. Südhof | Q97270 |
P2093 | author name string | X Shao | |
B A Davletov | |||
J Rizo | |||
R B Sutton | |||
P2860 | cites work | Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins | Q24323300 |
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold | Q27729921 | ||
Functional properties of multiple synaptotagmins in brain | Q28242788 | ||
Crystal structures of the helix-loop-helix calcium-binding proteins | Q28271755 | ||
Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins | Q28289561 | ||
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP | Q28302244 | ||
Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C | Q28576253 | ||
Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse | Q28587672 | ||
Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques | Q29614703 | ||
The synaptic vesicle cycle: a cascade of protein-protein interactions | Q29620168 | ||
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C | Q29620247 | ||
Protein structure determination in solution by two-dimensional and three-dimensional nuclear magnetic resonance spectroscopy | Q30421715 | ||
Calcium dependence of the rate of exocytosis in a synaptic terminal | Q34324078 | ||
Interaction of proteins with lipid headgroups: lessons from protein kinase C. | Q40832939 | ||
Synaptotagmin: a calcium sensor on the synaptic vesicle surface | Q48480063 | ||
Distinct Ca(2+)-dependent properties of the first and second C2-domains of synaptotagmin I. | Q49161795 | ||
1H and 15N resonance assignments and secondary structure of cellular retinoic acid-binding protein with and without bound ligand. | Q54021939 | ||
P433 | issue | 5272 | |
P407 | language of work or name | English | Q1860 |
P1104 | number of pages | 4 | |
P304 | page(s) | 248-251 | |
P577 | publication date | 1996-07-01 | |
P1433 | published in | Science | Q192864 |
P1476 | title | Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C | |
P478 | volume | 273 |
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Q28137740 | Alternative splicing of synaptotagmins involving transmembrane exon skipping |
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Q24685954 | Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb |
Q54502571 | Arabidopsis synaptotagmin 1 is required for the maintenance of plasma membrane integrity and cell viability. |
Q73924712 | Assignment of the 1H, 15N and 13C resonances of the calcium-free and calcium-bound forms of the first C2-domain of synaptotagmin I |
Q26269957 | Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1 |
Q28360864 | C2 domains from different Ca2+ signaling pathways display functional and mechanistic diversity |
Q29619459 | C2-domains, structure and function of a universal Ca2+-binding domain |
Q41541440 | Ca2+ and the regulation of neurotransmitter secretion |
Q35213277 | Ca2+ binding alters the interdomain flexibility between the two cytoplasmic calcium-binding domains in the Na+/Ca2+ exchanger |
Q24291150 | Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization |
Q26269956 | Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain? |
Q42033626 | Ca2+ modulation of cis-unsaturated fatty acid-induced mutant protein kinase C activity: indication of inhibitory Ca2+-binding site in protein kinase C-alpha |
Q27656957 | Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism |
Q30359420 | Ca2+-binding motif of βγ-crystallins. |
Q42917223 | Ca2+-controlled competitive diacylglycerol binding of protein kinase C isoenzymes in living cells |
Q36595702 | Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission |
Q26269884 | Calcium control of neurotransmitter release |
Q35752790 | Calcium triggers an intramolecular association of the C2 domains in synaptotagmin |
Q28278153 | Calcium-activated potassium channels |
Q47828162 | Calcium-dependent membrane penetration is a hallmark of the C2 domain of cytosolic phospholipase A2 whereas the C2A domain of synaptotagmin binds membranes electrostatically. |
Q36693214 | Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin |
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Q35794843 | Cellular and molecular interactions of phosphoinositides and peripheral proteins |
Q37239601 | Cellular membranes and lipid-binding domains as attractive targets for drug development |
Q24532452 | Characterization of KIAA1427 protein as an atypical synaptotagmin (Syt XIII) |
Q24569595 | Characterization of soluble forms of nonchimeric type V adenylyl cyclases |
Q82616680 | Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids |
Q41837612 | Comparative analysis of tandem C2 domains from the mammalian synaptotagmin family |
Q24321337 | Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2 |
Q27764892 | Crystal structure of the C2 domain from protein kinase C-delta |
Q26269931 | Crystal structure of the RIM1alpha C2B domain at 1.7 A resolution |
Q39643220 | Crystallization and preliminary crystallographic analysis of a C2 protein from Arabidopsis thaliana. |
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Q29618534 | Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis |
Q42159002 | Determination of the calcium-binding sites of the C2 domain of protein kinase Calpha that are critical for its translocation to the plasma membrane |
Q26269912 | Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release |
Q73703938 | Distinct Ca2+ binding properties of novel C2 domains of plant phospholipase dalpha and beta |
Q33906744 | Double C2 protein. A review. |
Q45084937 | Dual roles of the C2B domain of synaptotagmin I in synchronizing Ca2+-dependent neurotransmitter release. |
Q26799286 | Dynamics and Membrane Interactions of Protein Kinase C |
Q34103383 | EF-hand calcium-binding proteins. |
Q34110570 | Electrostatic control of the membrane targeting of C2 domains |
Q36297895 | Enlightening molecular mechanisms through study of protein interactions |
Q35123603 | Evolution, biochemistry and genetics of protein kinase C in fungi |
Q24311812 | Evolutionarily conserved multiple C2 domain proteins with two transmembrane regions (MCTPs) and unusual Ca2+ binding properties |
Q50034960 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release |
Q38201382 | Exocytosis and synaptic vesicle function |
Q74506578 | Functional analysis of the C2A domain of synaptotagmin 1: implications for calcium-regulated secretion |
Q24647716 | Functional and biochemical analysis of the C2 domains of synaptotagmin IV |
Q37013623 | Genetic analysis of synaptotagmin C2 domain specificity in regulating spontaneous and evoked neurotransmitter release |
Q26269936 | Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis |
Q28186545 | Genomic organisation and alternative splicing of human RIM1, a gene implicated in autosomal dominant cone-rod dystrophy (CORD7) |
Q36276750 | Getting a grip on calcium regulation |
Q28118077 | Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta |
Q74047725 | Independent folding and ligand specificity of the C2 calcium-dependent lipid binding domain of cytosolic phospholipase A2 |
Q40943094 | Investigating the role played by protein-lipid and protein-protein interactions in the membrane association of the p120GAP CaLB domain |
Q48051420 | Investigation of the Effect of Bilayer Composition on PKCα-C2 Domain Docking Using Molecular Dynamics Simulations. |
Q37040469 | Isolation of a calcium-binding protein of the acrosomal membrane of bovine spermatozoa |
Q24654170 | Janus kinases and focal adhesion kinases play in the 4.1 band: a superfamily of band 4.1 domains important for cell structure and signal transduction |
Q73203897 | Kinetics of synaptotagmin responses to Ca2+ and assembly with the core SNARE complex onto membranes |
Q77332922 | Lipid binding ridge on loops 2 and 3 of the C2A domain of synaptotagmin I as revealed by NMR spectroscopy |
Q41737527 | Lymphocyte granule-mediated cell death. |
Q54432027 | Mechanism of calcium gating in small-conductance calcium-activated potassium channels. |
Q30473073 | Membrane domain formation by calcium-dependent, lipid-binding proteins: insights from the C2 motif |
Q41740953 | Modulating protein kinase C signal transduction. |
Q33698787 | Molecular and biochemical properties and physiological roles of plant phospholipase D. |
Q39145271 | Molecular and enzymatic characterization of three phosphoinositide-specific phospholipase C isoforms from potato |
Q42651233 | Molecular cloning and functional analysis of polyphosphoinositide-dependent phospholipase D, PLDbeta, from Arabidopsis |
Q36888927 | Molecular heterogeneity of phospholipase D (PLD). Cloning of PLDgamma and regulation of plant PLDgamma, -beta, and -alpha by polyphosphoinositides and calcium |
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Q52565810 | Morphologically docked synaptic vesicles are reduced in synaptotagmin mutants of Drosophila. |
Q33896607 | Multiple forms of phospholipase D in plants: the gene family, catalytic and regulatory properties, and cellular functions |
Q26269911 | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis |
Q24310406 | N-copine: a novel two C2-domain-containing protein with neuronal activity-regulated expression |
Q38749071 | Non-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions |
Q40119866 | Noncovalent keystone interactions controlling biomembrane structure |
Q47373170 | Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses |
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Q51808788 | Phosphatidylinositol phosphates as co-activators of Ca2+ binding to C2 domains of synaptotagmin 1. |
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Q33850659 | Probing the determinants of diacylglycerol binding affinity in the C1B domain of protein kinase Cα. |
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Q42061701 | Real-time assay for monitoring membrane association of lipid-binding domains |
Q42073768 | Regulation by bivalent cations of phospholipid binding to the C2A domain of synaptotagmin III. |
Q34063787 | Regulation of exocytosis and fusion pores by synaptotagmin-effector interactions |
Q41382903 | Regulation of protein kinase C. |
Q28831105 | Ring-like oligomers of Synaptotagmins and related C2 domain proteins |
Q27933531 | Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae. |
Q43869321 | Role of electrostatic and hydrophobic interactions in Ca(2+)-dependent phospholipid binding by the C(2)A-domain from synaptotagmin I. |
Q43000381 | Roles of calcium ions in the membrane binding of C2 domains. |
Q35582307 | SNARE proteins contribute to calcium cooperativity of synaptic transmission |
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