Cellular and molecular interactions of phosphoinositides and peripheral proteins

scientific article published on 17 February 2014

Cellular and molecular interactions of phosphoinositides and peripheral proteins is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CHEMPHYSLIP.2014.02.002
P932PMC publication ID4484752
P698PubMed publication ID24556335

P50authorRobert V. StahelinQ54008523
P2093author name stringJordan L Scott
Cary T Frick
P2860cites workG-protein signaling through tubby proteinsQ24291262
The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphateQ24291846
FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartmentsQ24291986
Multivalent endosome targeting by homodimeric EEA1Q24291994
Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domainsQ24294673
The PX-BAR membrane-remodeling unit of sorting nexin 9Q24298249
The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALMQ24298394
Non-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9Q24299126
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranesQ24300526
Binding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activityQ24307944
Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interactionQ24307993
Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoidsQ24309456
Retroviral matrix domains share electrostatic homology: models for membrane binding function throughout the viral life cycleQ46745519
PTEN phosphatase selectively binds phosphoinositides and undergoes structural changesQ46791213
Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in miceQ46881275
A functional PtdIns(3)P-binding motifQ47713511
MeTaDoR: a comprehensive resource for membrane targeting domains and their host proteins.Q48387179
Ionization properties of phosphatidylinositol polyphosphates in mixed model membranesQ48469291
Excessive expression of synaptojanin in brains with Down syndromeQ48664137
Two lipid-packing sensor motifs contribute to the sensitivity of ArfGAP1 to membrane curvature.Q50336127
Regulation of KCNQ channels by manipulation of phosphoinositidesQ51030542
Medical complications in long-term survivors with X-linked myotubular myopathy.Q52179869
Phosphatidylinositol 3-phosphate induces the membrane penetration of the FYVE domains of Vps27p and Hrs.Q52596156
The molecular basis of the differential subcellular localization of FYVE domains.Q52652201
Structural and membrane binding analysis of the Phox homology domain of phosphoinositide 3-kinase-C2alpha.Q54453781
PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phoxQ57057849
Phosphatidylinositol 4,5-Bisphosphate-Induced Conformational Change of Ezrin and Formation of Ezrin OligomersQ57907600
Localization of a gene responsible for autosomal recessive demyelinating neuropathy with focally folded myelin sheaths to chromosome 11q23 by homozygosity mapping and haplotype sharingQ58001951
Computer Modeling of the Membrane Interaction of FYVE DomainsQ58006839
Phosphoinositide-specific phospholipase C-delta 1 binds with high affinity to phospholipid vesicles containing phosphatidylinositol 4,5-bisphosphateQ67507881
Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase CQ71142569
Binding kinetics and ligand specificity for the interactions of the C2B domain of synaptogmin II with inositol polyphosphates and phosphoinositidesQ74138378
Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detectionQ77555803
The enzymatic synthesis of inositol phosphatideQ78427468
Phosphatidylinositol-4,5-bisphosphate ionization and domain formation in the presence of lipids with hydrogen bond donor capabilitiesQ84596070
Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipidsQ24314531
GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote buddingQ24336708
Alternate splicing of dysferlin C2A confers Ca²⁺-dependent and Ca²⁺-independent binding for membrane repairQ24339610
Mutations in MTMR13, a new pseudophosphatase homologue of MTMR2 and Sbf1, in two families with an autosomal recessive demyelinating form of Charcot-Marie-Tooth disease associated with early-onset glaucomaQ24532011
Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activityQ24551012
Membrane insertion of the FYVE domain is modulated by pHQ24603721
Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequenceQ24612940
A systematic screen for protein-lipid interactions in Saccharomyces cerevisiaeQ24621326
Let's go bananas: revisiting the endocytic BAR codeQ24635636
Membrane lipids: where they are and how they behaveQ24653084
SMART 6: recent updates and new developmentsQ24655795
Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3-kinases: binding partners of SH3 domains?Q24674641
Phosphatidylinositol 3,5-bisphosphate: low abundance, high significanceQ26823539
PtdIns(4,5)P2-mediated cell signaling: emerging principles and PTEN as a paradigm for regulatory mechanismQ27002565
Membrane curvature and its generation by BAR proteinsQ27006768
Counterion-mediated cluster formation by polyphosphoinositidesQ27011678
Phosphoinositides: tiny lipids with giant impact on cell regulationQ27012953
Signaling through C2 domains: more than one lipid targetQ27014032
Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27pQ27618582
Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserineQ27620399
Structural mechanism of endosome docking by the FYVE domainQ27630275
The 2.7 A crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activationQ27632553
Curvature of clathrin-coated pits driven by epsinQ27639716
BAR domains as sensors of membrane curvature: the amphiphysin BAR structureQ27642663
Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificityQ27646147
A transforming mutation in the pleckstrin homology domain of AKT1 in cancerQ27646556
Structural and mechanistic insights into the association of PKC -C2 domain to PtdIns(4,5)P2Q27654558
PtdIns4 P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi traffickingQ27658740
Structural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs)Q27659933
Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domainsQ27660282
PI3K-Akt pathway: its functions and alterations in human cancerQ34362034
Membrane binding assays for peripheral proteins.Q34367949
Phosphoinositides differentially regulate protrudin localization through the FYVE domainQ34435861
Kinetic studies of protein-protein interactionsQ34525874
The Phox (PX) domain proteins and membrane trafficQ34539521
PIP(2) and proteins: interactions, organization, and information flowQ34623576
Phosphatidylserine is a critical modulator for Akt activationQ34712409
The PTEN-PI3K pathway: of feedbacks and cross-talksQ34828662
FERM domain phosphoinositide binding targets merlin to the membrane and is essential for its growth-suppressive functionQ35096540
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserineQ35130156
Genome-wide structural analysis reveals novel membrane binding properties of AP180 N-terminal homology (ANTH) domains.Q35310698
In situ quantitative imaging of cellular lipids using molecular sensorsQ35492502
ENTH/ANTH proteins and clathrin-mediated membrane buddingQ35600840
Ceramide kinase regulates the production of tumor necrosis factor α (TNFα) via inhibition of TNFα-converting enzymeQ35604572
A highly dynamic ER-derived phosphatidylinositol-synthesizing organelle supplies phosphoinositides to cellular membranesQ35607232
PtdIns5P: news and views of its appearance, disappearance and deedsQ35763394
Microarray analysis of Akt PH domain binding employing synthetic biotinylated analogs of all seven phosphoinositide headgroup isomersQ35784382
Phosphoinositides in constitutive membrane traffic.Q35842974
Electrostatic interactions drive membrane association of the human immunodeficiency virus type 1 Gag MA domainQ35857301
Design of protein membrane interaction inhibitors by virtual ligand screening, proof of concept with the C2 domain of factor VQ35921636
Membrane binding domainsQ36103518
Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cellsQ36118986
Inositol-lipid binding motifs: signal integrators through protein-lipid and protein-protein interactionsQ36125410
Metabolism and functions of phosphatidylserineQ36175131
Genome-wide functional annotation of dual-specificity protein- and lipid-binding modules that regulate protein interactionsQ36200455
Cellular lipidomicsQ36247057
Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cellsQ36274901
pH-dependent binding of the Epsin ENTH domain and the AP180 ANTH domain to PI(4,5)P2-containing bilayers.Q36282567
Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry.Q36285541
Phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) specifically induces membrane penetration and deformation by Bin/amphiphysin/Rvs (BAR) domainsQ36298326
Plasma membrane phosphoinositide organization by protein electrostaticsQ36327803
Oncogenic PI3K deregulates transcription and translationQ36337966
Mutations in phosphoinositide metabolizing enzymes and human diseaseQ36402106
Phosphatidylinositol 3-phosphate recognition and membrane docking by the FYVE domain.Q36462364
Structural basis for the interaction between the growth factor-binding protein GRB10 and the E3 ubiquitin ligase NEDD4Q27665387
Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) DomainQ27667394
Pb 2+ as Modulator of Protein–Membrane InteractionsQ27668029
Cd 2+ as a Ca 2+ Surrogate in Protein–Membrane Interactions: Isostructural but Not IsofunctionalQ27679536
Crystal structure of the pleckstrin homology domain from the ceramide transfer protein: implications for conformational change upon ligand bindingQ27680662
Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1Q27680751
Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in AutophagyQ27681186
Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?Q27766047
Phosphoinositides in cell regulation and membrane dynamicsQ27861051
How synaptotagmin promotes membrane fusion.Q27863355
Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domainsQ27933286
Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes.Q27933674
Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domainsQ27934605
Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndromeQ28117514
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identityQ28118990
PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapseQ28198985
Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domainsQ28203579
The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and manQ28207622
Characterization of lipid binding specificities of dysferlin C2 domains reveals novel interactions with phosphoinositidesQ28236858
Membrane-protein interactions in cell signaling and membrane traffickingQ28248356
Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndromeQ28268735
FYVE fingers bind PtdIns(3)PQ28279043
Translation of the phosphoinositide code by PI effectorsQ28285651
Epsin: inducing membrane curvatureQ28286739
C2 domains from different Ca2+ signaling pathways display functional and mechanistic diversityQ28360864
Emerging methodologies to investigate lipid-protein interactionsQ28386247
Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin IIQ28513379
Synaptotagmin-mediated bending of the target membrane is a critical step in Ca(2+)-regulated fusionQ28584744
PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosomeQ29543488
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolismQ29547302
Membrane recognition by phospholipid-binding domainsQ29614848
C2-domains, structure and function of a universal Ca2+-binding domainQ29619459
The PI(3)P interactome from a colon cancer cell.Q30009923
The Cdc42 binding and scaffolding activities of the fission yeast adaptor protein Scd2.Q30165115
Membrane fission is promoted by insertion of amphipathic helices and is restricted by crescent BAR domainsQ30461258
Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting.Q30478189
Organelle-specific, rapid induction of molecular activities and membrane tetheringQ30494251
Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination.Q30499793
An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathwaysQ30536393
Common exonic missense variants in the C2 domain of the human KIBRA protein modify lipid binding and cognitive performanceQ30540917
Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamicsQ30560982
Phosphatidylinositol-4,5-bisphosphate ionization in the presence of cholesterol, calcium or magnesium ionsQ30708792
Membrane association of the PTEN tumor suppressor: molecular details of the protein-membrane complex from SPR binding studies and neutron reflectionQ31055274
Kinetics of M1 muscarinic receptor and G protein signaling to phospholipase C in living cellsQ33615022
Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signalingQ33929518
Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switchQ33947927
Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domainQ34057438
A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5P and other phosphoinositidesQ34108633
Electrostatic control of the membrane targeting of C2 domainsQ34110570
Mutation of the SBF2 gene, encoding a novel member of the myotubularin family, in Charcot-Marie-Tooth neuropathy type 4B2/11p15.Q34173425
Domain formation in phosphatidylinositol monophosphate/phosphatidylcholine mixed vesiclesQ34185632
A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin.Q34290588
Live cell imaging of phosphoinositide dynamics with fluorescent protein domainsQ36479477
Ras GTPase activating (RasGAP) activity of the dual specificity GAP protein Rasal requires colocalization and C2 domain binding to lipid membranesQ36512303
Acute manipulation of phosphoinositide levels in cellsQ36528094
Determining selectivity of phosphoinositide-binding domainsQ36531104
The role of electrostatics in protein-membrane interactionsQ36575065
Membrane binding and subcellular targeting of C2 domainsQ36582982
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosisQ36602177
PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membraneQ36630120
The Ebola virus matrix protein penetrates into the plasma membrane: a key step in viral protein 40 (VP40) oligomerization and viral egressQ36636069
Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagminQ36693214
Pleckstrin homology (PH) domains and phosphoinositidesQ36711258
Surface plasmon resonance: a useful technique for cell biologists to characterize biomolecular interactions.Q36717368
The molecular basis of ceramide-1-phosphate recognition by C2 domains.Q36744081
Molecular mechanism of membrane targeting by the GRP1 PH domainQ36745060
Doc2b promotes GLUT4 exocytosis by activating the SNARE-mediated fusion reaction in a calcium- and membrane bending-dependent mannerQ36758428
PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identityQ36822749
Investigation of the binding geometry of a peripheral membrane proteinQ36837728
Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolismQ36869216
Mechanistic similarities in docking of the FYVE and PX domains to phosphatidylinositol 3-phosphate containing membranes.Q36914141
Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complexQ37000587
Cellular membranes and lipid-binding domains as attractive targets for drug developmentQ37239601
Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2).Q37292741
High-throughput fluorescence assay for membrane-protein interactionQ37305439
Lipid binding domains: more than simple lipid effectors.Q37325368
Membrane shaping by the Bin/amphiphysin/Rvs (BAR) domain protein superfamilyQ37902570
Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in diseaseQ37968311
Conditional peripheral membrane proteins: facing up to limited specificityQ37970875
Phosphoinositides and PDZ domain scaffoldsQ38115243
PtdIns(4)P signalling and recognition systemsQ38115244
Global approaches for the elucidation of phosphoinositide-binding proteinsQ38162053
Interplay between phosphoinositide lipids and calcium signals at the leading edge of chemotaxing ameboid cellsQ38180908
Functional diversity of C2 domains of synaptotagmin family. Mutational analysis of inositol high polyphosphate binding domain.Q38289467
Mutation analysis of SYNJ1: a possible candidate gene for chromosome 21q22-linked bipolar disorderQ38299200
Identification of PIK3C3 promoter variant associated with bipolar disorder and schizophrenia.Q38341807
Molecular determinants of the myristoyl-electrostatic switch of MARCKS.Q38354365
Differential isolation and identification of PI(3)P and PI(3,5)P2 binding proteins from Arabidopsis thaliana using an agarose-phosphatidylinositol-phosphate affinity chromatographyQ39355140
Phosphatidylinositol 3,4,5-trisphosphate activity probes for the labeling and proteomic characterization of protein binding partnersQ39445075
Molecular mechanisms of membrane deformation by I-BAR domain proteins.Q39894096
Membrane phosphatidylserine regulates surface charge and protein localizationQ40026492
Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channelsQ40228821
Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modesQ40251292
Receptor activation alters inner surface potential during phagocytosisQ40252897
Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phoxQ40674156
The molecular basis of differential subcellular localization of C2 domains of protein kinase C-alpha and group IVa cytosolic phospholipase A2.Q40676859
Electric fields at the plasma membrane level: a neglected element in the mechanisms of cell signallingQ41096383
C2 domain membrane penetration by group IVA cytosolic phospholipase A₂ induces membrane curvature changesQ41292274
A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membraneQ41718569
The C2 domains of granuphilin are high-affinity sensors for plasma membrane lipids.Q41901134
Synaptojanin 1-mediated PI(4,5)P2 hydrolysis is modulated by membrane curvature and facilitates membrane fissionQ41984022
Real-time assay for monitoring membrane association of lipid-binding domainsQ42061701
Structural bioinformatics prediction of membrane-binding proteinsQ42119485
ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif.Q42268960
Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domainQ42458279
Multiple pathways of inositol polyphosphate metabolism in angiotensin-stimulated adrenal glomerulosa cellsQ42515740
Ubiquitin interacts with the Tollip C2 and CUE domains and inhibits binding of Tollip to phosphoinositidesQ42587720
Combined electrostatics and hydrogen bonding determine intermolecular interactions between polyphosphoinositidesQ42727801
Synergistic effect of Pb(2+) and phosphatidylinositol 4,5-bisphosphate on C2 domain-membrane interactionsQ43178812
Differential roles of ionic, aliphatic, and aromatic residues in membrane-protein interactions: a surface plasmon resonance study on phospholipases A2.Q43569366
Polymorphism screening of PIK4CA: possible candidate gene for chromosome 22q11-linked psychiatric disorders.Q44259408
Multivalent mechanism of membrane insertion by the FYVE domainQ44631903
Polymorphism Screening of PIP5K2A: A Candidate Gene for Chromosome 10p‐Linked Psychiatric DisordersQ44634488
Membrane binding of myristylated peptides corresponding to the NH2 terminus of Src.Q44697710
Ceramide 1-phosphate acts as a positive allosteric activator of group IVA cytosolic phospholipase A2 alpha and enhances the interaction of the enzyme with phosphatidylcholine.Q44908854
Ceramide-1-phosphate binds group IVA cytosolic phospholipase a2 via a novel site in the C2 domainQ44928988
The C2 domain of Tollip, a Toll-like receptor signalling regulator, exhibits broad preference for phosphoinositidesQ44962988
Lipid-mediated membrane binding properties of Disabled-2.Q44968220
P407language of work or nameEnglishQ1860
P921main subjectlipid bindingQ14358833
FYVE zinc fingerQ24782563
molecular interactionQ33059490
P304page(s)3-18
P577publication date2014-02-17
P1433published inChemistry and Physics of LipidsQ15746139
P1476titleCellular and molecular interactions of phosphoinositides and peripheral proteins
P478volume182

Reverse relations

cites work (P2860)
Q41371801Association of Peripheral Membrane Proteins with Membranes: Free Energy of Binding of GRP1 PH Domain with Phosphatidylinositol Phosphate-Containing Model Bilayers
Q45780754CHIP as a membrane-shuttling proteostasis sensor.
Q40382341Characterization of PROPPIN-Phosphoinositide Binding and Role of Loop 6CD in PROPPIN-Membrane Binding
Q45397573Computational and theoretical approaches for studies of a lipid recognition protein on biological membranes.
Q90131372Computer simulations of protein-membrane systems
Q41447387Disruption of the plant-specific CFS1 gene impairs autophagosome turnover and triggers EDS1-dependent cell death.
Q41871308Dynamic interactions between a membrane binding protein and lipids induce fluctuating diffusivity.
Q35762799Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain
Q39592336Interactions of Pleckstrin Homology Domains with Membranes: Adding Back the Bilayer via High-Throughput Molecular Dynamics.
Q46169406Interactions of peripheral proteins with model membranes as viewed by molecular dynamics simulations
Q41637191Investigation of the biophysical properties of a fluorescently modified ceramide-1-phosphate.
Q50090782Investigation of the phosphatidylserine binding properties of the lipid biosensor, Lactadherin C2 (LactC2), in different membrane environments
Q64973699Is Calcium Fine-Tuning Phosphoinositide-Mediated Signaling Events Through Clustering?
Q55432297Lipid-Protein Interactions Are Unique Fingerprints for Membrane Proteins.
Q26778952Membrane Binding and Modulation of the PDZ Domain of PICK1
Q92782198Membrane Recognition and Binding by the Phosphatidylinositol Phosphate Kinase PIP5K1A: A Multiscale Simulation Study
Q21131091Membrane binding and bending in Ebola VP40 assembly and egress
Q89597244Molecular Analysis of Membrane Targeting by the C2 Domain of the E3 Ubiquitin Ligase Smurf1
Q90017229Multiple lipid binding sites determine the affinity of PH domains for phosphoinositide-containing membranes
Q63547192Multiscale Simulations of Biological Membranes: The Challenge To Understand Biological Phenomena in a Living Substance
Q46428170Nectin-like 4 Complexes with Choline Transporter-like Protein-1 and Regulates Schwann Cell Choline Homeostasis and Lipid Biogenesis in Vitro
Q38724553Phosphatidylserine Stimulates Ceramide 1-Phosphate (C1P) Intermembrane Transfer by C1P Transfer Proteins
Q46294972Phosphoinositide Diversity, Distribution, and Effector Function: Stepping Out of the Box.
Q38892847Phospholipid composition and a polybasic motif determine D6 PROTEIN KINASE polar association with the plasma membrane and tropic responses.
Q27932915Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway
Q47758406Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins.
Q45875437Pleckstrin homology domain of p210 BCR-ABL interacts with cardiolipin to regulate its mitochondrial translocation and subsequent mitophagy
Q89151740Sensitivity of peripheral membrane proteins to the membrane context: A case study of phosphatidylserine and the TIM proteins
Q36406344Sphingolipid transfer proteins defined by the GLTP-fold
Q30391512Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis
Q52724308Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.
Q48183538The ARF guanine nucleotide exchange factor GBF1 is targeted to Golgi membranes through a PIP-binding domain.
Q34580401The Ebola virus matrix protein VP40 selectively induces vesiculation from phosphatidylserine-enriched membranes
Q55160467The PH domain from the Toxoplasma gondii PH-containing protein-1 (TgPH1) serves as an ectopic reporter of phosphatidylinositol 3-phosphate in mammalian cells.
Q92224343The energetics of protein-lipid interactions as viewed by molecular simulations

Search more.