scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1020863681 |
P356 | DOI | 10.1038/NSMB707 |
P3181 | OpenCitations bibliographic resource ID | 4081397 |
P698 | PubMed publication ID | 14718922 |
P5875 | ResearchGate publication ID | 8922326 |
P50 | author | Thomas C. Südhof | Q97270 |
Josep Rizo | Q58110018 | ||
P2093 | author name string | Shuzo Sugita | |
Stefan H Gerber | |||
Jesus Garcia | |||
P2860 | cites work | Initial sequencing and analysis of the human genome | Q21045365 |
Aczonin, a 550-kD putative scaffolding protein of presynaptic active zones, shares homology regions with Rim and Bassoon and binds profilin | Q22010610 | ||
Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2 | Q24321337 | ||
Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins | Q24323300 | ||
The C2 domain calcium-binding motif: structural and functional diversity | Q24674621 | ||
Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain? | Q26269956 | ||
An unusual C(2)-domain in the active-zone protein piccolo: implications for Ca(2+) regulation of neurotransmitter release | Q26269974 | ||
Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Q26778405 | ||
PROCHECK: a program to check the stereochemical quality of protein structures | Q26778411 | ||
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures | Q26778412 | ||
Structure of the Janus-faced C2B domain of rabphilin | Q27620366 | ||
Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine | Q27620399 | ||
Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine | Q27637071 | ||
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold | Q27729921 | ||
A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1 | Q27734937 | ||
Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+ | Q27766029 | ||
Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change? | Q27766047 | ||
Protein structure comparison by alignment of distance matrices | Q27860798 | ||
NMRPipe: a multidimensional spectral processing system based on UNIX pipes | Q27860859 | ||
NMR View: A computer program for the visualization and analysis of NMR data | Q27860951 | ||
Protein backbone angle restraints from searching a database for chemical shift and sequence homology | Q27861108 | ||
Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase | Q28131695 | ||
Synaptotagmin I functions as a calcium regulator of release probability | Q28204147 | ||
Synaptotagmin-syntaxin interaction: the C2 domain as a Ca2+-dependent electrostatic switch | Q28302242 | ||
Piccolo, a presynaptic zinc finger protein structurally related to bassoon | Q28579838 | ||
Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques | Q29614703 | ||
C2-domains, structure and function of a universal Ca2+-binding domain | Q29619459 | ||
Alternative splicing of potassium channels: a dynamic switch of cellular excitability. | Q30328570 | ||
Molecular determinants of presynaptic active zones | Q33941567 | ||
Synaptotagmins: why so many? | Q34460901 | ||
Alternative splicing: multiple control mechanisms and involvement in human disease | Q34586931 | ||
Role of synaptotagmin in Ca2+-triggered exocytosis | Q34669186 | ||
Short-term synaptic plasticity | Q38613257 | ||
Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain. | Q41064448 | ||
Response of hippocampal synapses to natural stimulation patterns | Q41608461 | ||
Interplay between facilitation, depression, and residual calcium at three presynaptic terminals. | Q42483283 | ||
Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C | Q71142569 | ||
Kinetics of synaptotagmin responses to Ca2+ and assembly with the core SNARE complex onto membranes | Q73203897 | ||
Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I | Q77216937 | ||
Activation of phospholipase C delta1 through C2 domain by a Ca(2+)-enzyme-phosphatidylserine ternary complex | Q78038046 | ||
Enhanced-Sensitivity Triple-Resonance Spectroscopy with Minimal H2O Saturation | Q108784215 | ||
A Gradient-Enhanced HCCH-TOCSY Experiment for Recording Side-Chain 1H and 13C Correlations in H2O Samples of Proteins | Q110644268 | ||
P433 | issue | 1 | |
P921 | main subject | alternative mRNA splicing, via spliceosome | Q21114084 |
P1104 | number of pages | 9 | |
P304 | page(s) | 45-53 | |
P577 | publication date | 2004-01-01 | |
P1433 | published in | Nature Structural & Molecular Biology | Q1071739 |
P1476 | title | A conformational switch in the Piccolo C2A domain regulated by alternative splicing | |
P478 | volume | 11 |
Q33763419 | A role for indels in the evolution of Cro protein folds |
Q30366272 | Alternative splicing and protein structure evolution. |
Q40544608 | Alternative splicing in the voltage-sensing region of N-Type CaV2.2 channels modulates channel kinetics |
Q34666751 | An expectation-maximization algorithm for probabilistic reconstructions of full-length isoforms from splice graphs |
Q43825905 | Characterization of the impact of alternative splicing on protein dynamics: the cases of glutathione S-transferase and ectodysplasin-A isoforms |
Q21999763 | Creation and disruption of protein features by alternative splicing -- a novel mechanism to modulate function |
Q26269931 | Crystal structure of the RIM1alpha C2B domain at 1.7 A resolution |
Q46744943 | Crystal structure of the RIM2 C2A-domain at 1.4 A resolution |
Q33780318 | Distinct functions of alternatively spliced isoforms encoded by zebrafish mef2ca and mef2cb |
Q36297895 | Enlightening molecular mechanisms through study of protein interactions |
Q37280609 | Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo |
Q46807757 | Identification of Piccolo as a regulator of behavioral plasticity and dopamine transporter internalization. |
Q37661829 | LenVarDB: database of length-variant protein domains |
Q90005476 | Metal Binding Antimicrobial Peptides in Nanoparticle Bio-functionalization: New Heights in Drug Delivery and Therapy |
Q37157940 | Molecular determinants and evolutionary dynamics of wobble splicing |
Q24530809 | Non-EST based prediction of exon skipping and intron retention events using Pfam information |
Q47108598 | Piccolo Promotes Vesicle Replenishment at a Fast Central Auditory Synapse |
Q26269909 | Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis |
Q51109553 | Piccolo mediates EGFR signaling and acts as a prognostic biomarker in esophageal squamous cell carcinoma. |
Q24812842 | Protein modularity of alternatively spliced exons is associated with tissue-specific regulation of alternative splicing |
Q43052902 | Rational design of a novel calcium-binding site adjacent to the ligand-binding site on CD2 increases its CD48 affinity |
Q27650055 | Regulation of Neurexin 1β Tertiary Structure and Ligand Binding through Alternative Splicing |
Q26770446 | Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone |
Q42276816 | Roles of alternative splicing in modulating transcriptional regulation |
Q75247050 | Sculpting a domain by splicing |
Q33325721 | Selection against tandem splice sites affecting structured protein regions |
Q36458375 | Sequential reorganization of beta-sheet topology by insertion of a single strand |
Q28564444 | Solution structure of the RIM1alpha PDZ domain in complex with an ELKS1b C-terminal peptide |
Q27663355 | Splice Form Dependence of β-Neurexin/Neuroligin Binding Interactions |
Q26269910 | Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7 |
Q26269950 | Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch |
Q24316485 | Structure and Ca²⁺-binding properties of the tandem C₂ domains of E-Syt2 |
Q30392268 | Systematic analysis of short internal indels and their impact on protein folding |
Q30360130 | The (in)dependence of alternative splicing and gene duplication |
Q27643300 | The C2A-C2B linker defines the high affinity Ca(2+) binding mode of rabphilin-3A |
Q27660174 | The Heterohexameric Complex Structure, a Component in the Non-classical Pathway for Fibroblast Growth Factor 1 (FGF1) Secretion |
Q37361167 | The Vesicle Priming Factor CAPS Functions as a Homodimer via C2 Domain Interactions to Promote Regulated Vesicle Exocytosis. |
Q64263143 | The germ cell marker dead end reveals alternatively spliced transcripts with dissimilar expression |
Q26269863 | The presynaptic active zone |
Q47342203 | The presynaptic scaffolding protein Piccolo organizes the readily releasable pool at the calyx of Held |
Q80380254 | Three-dimensional structure of an independently folded extracellular domain of human amyloid-beta precursor protein |
Q37045527 | Understanding the molecular machinery of genetics through 3D structures |
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