Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone

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Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone is …
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scholarly articleQ13442814

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P356DOI10.3389/FNSYN.2015.00019
P3181OpenCitations bibliographic resource ID650070
P932PMC publication ID4709825
P698PubMed publication ID26793095
P5875ResearchGate publication ID290507356

P50authorEckart D. GundelfingerQ28833533
P2093author name stringCraig C Garner
Carsten Reissner
P2860cites workGenomic fold assignment and rational modeling of proteins of biological interestQ74286171
Long-term relationships between synaptic tenacity, synaptic remodeling, and network activityQ21145818
Aczonin, a 550-kD putative scaffolding protein of presynaptic active zones, shares homology regions with Rim and Bassoon and binds profilinQ22010610
Mover is a novel vertebrate-specific presynaptic protein with differential distribution at subsets of CNS synapsesQ24293649
The Protein Data BankQ24515306
Mechanism of activation of the Formin protein Daam1Q24657453
Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter releaseQ24676624
Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complexQ24678467
Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosisQ26269821
The presynaptic active zoneQ26269863
RIM genes differentially contribute to organizing presynaptic release sitesQ26269874
RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zoneQ26269881
Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosisQ26269909
RIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13Q26269920
An unusual C(2)-domain in the active-zone protein piccolo: implications for Ca(2+) regulation of neurotransmitter releaseQ26269974
Molecular mechanisms driving homeostatic plasticity of neurotransmitter releaseQ26823427
Actin- and dynamin-dependent maturation of bulk endocytosis restores neurotransmission following synaptic depletionQ27303036
A conformational switch in the Piccolo C2A domain regulated by alternative splicingQ27642933
Protein structure prediction on the Web: a case study using the Phyre serverQ27860664
RIBEYE, a component of synaptic ribbons: a protein's journey through evolution provides insight into synaptic ribbon functionQ28143542
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1Q28214701
The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein PiccoloQ28217022
Metabolic turnover of synaptic proteins: kinetics, interdependencies and implications for synaptic maintenanceQ28487557
Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparationsQ28509113
Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and PiccoloQ28512052
Identification and immunocytochemical characterization of Piccolino, a novel Piccolo splice variant selectively expressed at sensory ribbon synapses of the eye and earQ28535170
Assembly of active zone precursor vesicles: obligatory trafficking of presynaptic cytomatrix proteins Bassoon and Piccolo via a trans-Golgi compartmentQ28565921
Localization of the presynaptic cytomatrix protein Piccolo at ribbon and conventional synapses in the rat retina: comparison with BassoonQ28570505
Differential expression of active zone proteins in neuromuscular junctions suggests functional diversificationQ28571292
Bassoon speeds vesicle reloading at a central excitatory synapse.Q39754011
The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid raftsQ39863117
Presynapses go nuclear!Q39878042
Integration of ATP, cAMP, and Ca2+ signals in insulin granule exocytosisQ40488471
Modulation of Presynaptic Release Probability by the Vertebrate-Specific Protein MoverQ41545604
Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differencesQ41692457
Assembly of presynaptic active zones from cytoplasmic transport packetsQ41730812
Investigating interactions mediated by the presynaptic protein bassoon in living cells by Foerster's resonance energy transfer and fluorescence lifetime imaging microscopyQ41963835
Presynaptic calcium channels and α3-integrins are complexed with synaptic cleft laminins, cytoskeletal elements and active zone componentsQ42385886
Enhancement of the endosomal endocytic pathway increases quantal sizeQ42410780
Differential expression of the presynaptic cytomatrix protein bassoon among ribbon synapses in the mammalian retinaQ42479967
O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometryQ42679419
RIM binding proteins (RBPs) couple Rab3-interacting molecules (RIMs) to voltage-gated Ca(2+) channelsQ42861890
Ultrastructural localization of active zone and synaptic vesicle proteins in a preassembled multi-vesicle transport aggregateQ42941268
Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing.Q45970083
A presynaptic role for the cytomatrix protein GIT in synaptic vesicle recycling.Q46093342
Identification of Piccolo as a regulator of behavioral plasticity and dopamine transporter internalization.Q46807757
Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in DrosophilaQ47072025
Functional regions of the presynaptic cytomatrix protein bassoon: significance for synaptic targeting and cytomatrix anchoring.Q47822813
Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse.Q48136713
Analysis of synaptic ultrastructure without fixative using high-pressure freezing and tomography.Q48307568
Unitary assembly of presynaptic active zones from Piccolo-Bassoon transport vesiclesQ48323672
Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoonQ48368670
The presynaptic active zone protein bassoon is essential for photoreceptor ribbon synapse formation in the retinaQ48368679
Differential distribution of release-related proteins in the hippocampal CA3 area as revealed by freeze-fracture replica labelingQ48830783
Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levelsQ48887497
Overexpression of piccolo C2A domain induces depression-like behavior in miceQ48975453
Hair cell synaptic ribbons are essential for synchronous auditory signalling.Q50473698
Developmental changes in presynaptic calcium channels coupled to glutamate release in cultured rat hippocampal neurons.Q52207839
Mammalian Abp1, a Signal-Responsive F-Actin–Binding Protein, Links the Actin Cytoskeleton to Endocytosis via the Gtpase DynaminQ57373370
A synaptic laminin–calcium channel interaction organizes active zones in motor nerve terminalsQ59061359
Assembly of new individual excitatory synapses: time course and temporal order of synaptic molecule recruitmentQ74158298
Assembling the presynaptic active zone: a characterization of an active one precursor vesicleQ28571859
Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradationQ28572409
Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release siteQ28576284
Piccolo, a presynaptic zinc finger protein structurally related to bassoonQ28579838
Bassoon, a novel zinc-finger CAG/glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminalsQ28581176
Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosisQ28586557
Polarized targeting of neurexins to synapses is regulated by their C-terminal sequencesQ28588666
A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1Q28595053
Dynein light chain regulates axonal trafficking and synaptic levels of BassoonQ28909809
RIBEYE, a Component of Synaptic RibbonsQ29540824
Bassoon and the synaptic ribbon organize Ca²+ channels and vesicles to add release sites and promote refillingQ30497701
Coordinated trafficking of synaptic vesicle and active zone proteins prior to synapse formationQ30500621
Comprehensive identification of phosphorylation sites in postsynaptic density preparationsQ33232861
The role of ARF and Rab GTPases in membrane transportQ33712473
Molecular determinants of presynaptic active zonesQ33941567
Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain.Q34093833
In vivo knockdown of Piccolino disrupts presynaptic ribbon morphology in mouse photoreceptor synapsesQ34127109
Interactions between Piccolo and the actin/dynamin-binding protein Abp1 link vesicle endocytosis to presynaptic active zonesQ34185752
Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosisQ34281843
Active zone protein Bassoon co-localizes with presynaptic calcium channel, modifies channel function, and recovers from aging related loss by exerciseQ34305261
Differential spatial expression and subcellular localization of CtBP family members in rodent brain.Q34321641
Piccolo, a novel 420 kDa protein associated with the presynaptic cytomatrixQ34405757
Synaptic organizing complexesQ34468861
Piccolo Directs Activity Dependent F-Actin Assembly from Presynaptic Active Zones via Daam1.Q34472870
Molecular mechanisms of CNS synaptogenesisQ34612370
Regulation of presynaptic anchoring of the scaffold protein Bassoon by phosphorylation-dependent interaction with 14-3-3 adaptor proteinsQ34630058
Three-dimensional architecture of presynaptic terminal cytomatrix.Q34642485
Syntabulin-kinesin-1 family member 5B-mediated axonal transport contributes to activity-dependent presynaptic assembly.Q34646100
TrkB/BDNF-dependent striatal plasticity and behavior in a genetic model of epilepsy: modulation by valproic acidQ34660982
Mover is a homomeric phospho-protein present on synaptic vesiclesQ34749299
Multiple RIBEYE-RIBEYE interactions create a dynamic scaffold for the formation of synaptic ribbonsQ34805032
Piccolo regulates the dynamic assembly of presynaptic F-actinQ35533808
Historical review: another 50th anniversary--new periodicities in coiled coilsQ35601824
BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neuronsQ35841742
Presynaptic active zones in invertebrates and vertebratesQ36004250
Formin proteins: a domain-based approach.Q36160324
Distinct synaptic and neurochemical changes to the granule cell-CA3 projection in Bassoon mutant miceQ36191842
Mechanisms of vertebrate synaptogenesisQ36196530
Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymersQ36201956
Molecular details of formin-mediated actin assemblyQ36346689
The multiple activities of CtBP/BARS proteins: the Golgi viewQ36398905
Synaptic proteome changes in mouse brain regions upon auditory discrimination learningQ36431821
Fife, a Drosophila Piccolo-RIM homolog, promotes active zone organization and neurotransmitter releaseQ36474425
Molecular organization of the presynaptic active zoneQ36545836
Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosisQ36677497
Transcriptional regulation by C-terminal binding proteinsQ36750450
Protein components of a rat brain synaptic junctional protein preparationQ36832143
Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zonesQ37044607
Formation of Golgi-derived active zone precursor vesicles.Q37117339
Ultrafast endocytosis at Caenorhabditis elegans neuromuscular junctionsQ37145198
Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptidesQ37211310
Rapid assembly of functional presynaptic boutons triggered by adhesive contactsQ37361929
Nucleocytoplasmic protein shuttling: the direct route in synapse-to-nucleus signaling.Q37518465
Molecular profiling reveals synaptic release machinery in Merkel cells.Q37569634
Neuronal signaling through endocytosisQ37615176
Ultrafast endocytosis at mouse hippocampal synapses.Q37642826
Structural and functional plasticity of the cytoplasmic active zoneQ37787424
Presynaptic function in health and diseaseQ37877363
Molecular organization and plasticity of the cytomatrix at the active zoneQ37949766
Active zones of mammalian neuromuscular junctions: formation, density, and agingQ38068532
Components of the CtBP1/BARS-dependent fission machinery.Q38133390
Presynaptic and postsynaptic scaffolds: dynamics fast and slow.Q38194447
Macromolecular transport in synapse to nucleus communication.Q38298415
D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.Q38672905
Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse.Q38797684
Bassoon specifically controls presynaptic P/Q-type Ca(2+) channels via RIM-binding proteinQ39008473
Presynaptic cytomatrix protein bassoon is localized at both excitatory and inhibitory synapses of rat brainQ39749339
P407language of work or nameEnglishQ1860
P921main subjectBassoonQ21981510
Piccolo (presynaptic cytomatrix protein)Q21989353
P304page(s)19
P577publication date2015-01-01
P1433published inFrontiers in synaptic neuroscienceQ27723479
P1476titleRole of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone
P478volume7

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cites work (P2860)
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