Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila

scientific article published in March 2006

Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEURON.2006.02.008
P698PubMed publication ID16543132
P5875ResearchGate publication ID7235829

P50authorRobert J KittelQ41788909
P2093author name stringGang Qin
Manuela Schmidt
Tobias M Rasse
Stephan J Sigrist
Carolin Wichmann
Erich Buchner
Alois Hofbauer
Marie-Christine Dabauvalle
Esther Asan
Sigrid Buchner
Isabell Schwenkert
Dhananjay A Wagh
Heike Dürrbeck
P2860cites workFlyBase: genes and gene modelsQ24794226
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
P304page(s)833-844
P577publication date2006-03-01
P1433published inNeuronQ3338676
P1476titleBruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila
P478volume49

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Q37996017Presynaptic Active Zone Density during Development and Synaptic Plasticity
Q36375613Presynaptic Aβ40 prevents synapse addition in the adult Drosophila neuromuscular junction
Q37441300Presynaptic CK2 promotes synapse organization and stability by targeting Ankyrin2.
Q33793623Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons
Q36004250Presynaptic active zones in invertebrates and vertebrates
Q47314059Presynaptic active zones of mammalian neuromuscular junctions: Nanoarchitecture and selective impairments in aging.
Q34179677Presynaptic activity and CaMKII modulate retrograde semaphorin signaling and synaptic refinement.
Q34378519Presynaptic alpha2delta-3 is required for synaptic morphogenesis independent of its Ca2+-channel functions
Q42599515Presynaptic calcium channel localization and calcium-dependent synaptic vesicle exocytosis regulated by the Fuseless protein
Q37181389Presynaptic secretion of mind-the-gap organizes the synaptic extracellular matrix-integrin interface and postsynaptic environments
Q55408929Prior activity of olfactory receptor neurons is required for proper sensory processing and behavior in Drosophila larvae.
Q35568909Prodomain removal enables neto to stabilize glutamate receptors at the Drosophila neuromuscular junction
Q41575899Programmed cell death in type II neuroblast lineages is required for central complex development in the Drosophila brain
Q89531637Proportional Downscaling of Glutamatergic Release Sites by the General Anesthetic Propofol at Drosophila Motor Nerve Terminals
Q40909612Protein composition of immunoprecipitated synaptic ribbons
Q34528520Putative excitatory and putative inhibitory inputs are localised in different dendritic domains in a Drosophila flight motoneuron
Q30586285Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states
Q36450432RIM promotes calcium channel accumulation at active zones of the Drosophila neuromuscular junction.
Q83229182RIM-BP2 primes synaptic vesicles recruitment of Munc13-1 at hippocampal mossy fiber synapses
Q39872809RSY-1 is a local inhibitor of presynaptic assembly in C. elegans
Q37484962Rab3 dynamically controls protein composition at active zones.
Q36686132Rab3-GEF Controls Active Zone Development at the Drosophila Neuromuscular Junction.
Q52719093Rapid active zone remodeling during synaptic plasticity.
Q24651888Rapid activity-dependent modifications in synaptic structure and function require bidirectional Wnt signaling
Q89799301Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle:Ca2+ channel distances
Q41461072Reactive oxygen species act remotely to cause synapse loss in a Drosophila model of developmental mitochondrial encephalopathy
Q60950835Reactive oxygen species regulate activity-dependent neuronal plasticity in
Q89129119Reconfiguration of a Multi-oscillator Network by Light in the Drosophila Circadian Clock
Q39705519Regeneration of olfactory afferent axons in the locust brain
Q47326679Regulated Alternative Splicing of DrosophilaDscam2  Is Necessary for Attaining the Appropriate Number of Photoreceptor Synapses
Q41969892Regulation of Fasciclin II and synaptic terminal development by the splicing factor beag
Q55056714Regulation of synaptic architecture and synaptic vesicle pools by Nervous wreck at Drosophila Type 1b glutamatergic synapses.
Q34999362Regulation of synaptic development and function by the Drosophila PDZ protein Dyschronic
Q30407369Relating structure and function of inner hair cell ribbon synapses
Q37282617Retrograde BMP signaling at the synapse: a permissive signal for synapse maturation and activity-dependent plasticity.
Q37677612Retrograde neurotrophin signaling through Tollo regulates synaptic growth in Drosophila
Q34806602Rhythmic changes in synapse numbers in Drosophila melanogaster motor terminals
Q26770446Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone
Q35514245S6 kinase localizes to the presynaptic active zone and functions with PDK1 to control synapse development
Q46400383STED Imaging in Drosophila Brain Slices
Q36669891Scaffolding proteins at the Drosophila neuromuscular junction
Q38116904Seeing the forest tree by tree: super-resolution light microscopy meets the neurosciences
Q48293581Sensory integration and neuromodulatory feedback facilitate Drosophila mechanonociceptive behavior
Q58553556Sentryn and SAD Kinase Link the Guided Transport and Capture of Dense Core Vesicles in
Q37414024Serotonergic Modulation Differentially Targets Distinct Network Elements within the Antennal Lobe of Drosophila melanogaster
Q34215078Sexual dimorphism in the fly brain.
Q36932899Shank Modulates Postsynaptic Wnt Signaling to Regulate Synaptic Development.
Q57807821Shep interacts with posttranscriptional regulators to control dendrite morphogenesis in sensory neurons
Q26824581Shocking revelations and saccharin sweetness in the study of Drosophila olfactory memory
Q42024986Sialyltransferase regulates nervous system function in Drosophila
Q59326833Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant
Q37305913Small heat shock proteins mediate cell-autonomous and -nonautonomous protection in a Drosophila model for environmental-stress-induced degeneration.
Q27329979Spastic paraplegia mutation N256S in the neuronal microtubule motor KIF5A disrupts axonal transport in a Drosophila HSP model
Q27305389Specification of individual adult motor neuron morphologies by combinatorial transcription factor codes
Q27340068Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release
Q89964340Stochastic and Arbitrarily Generated Input Patterns to the Mushroom Bodies Can Serve as Conditioned Stimuli in Drosophila
Q89982514Structural Remodeling of Active Zones Is Associated with Synaptic Homeostasis
Q52608792Structural and Molecular Properties of Insect Type II Motor Axon Terminals.
Q37787424Structural and functional plasticity of the cytoplasmic active zone
Q55511427Structural aspects of plasticity in the nervous system of Drosophila.
Q33986339Structural organization of the presynaptic density at identified synapses in the locust central nervous system
Q46173319Structure and development of the subesophageal zone of the Drosophila brain. II. Sensory compartments.
Q39897144Structure of the adult central complex in Drosophila: organization of distinct neuronal subsets
Q30497802Sugar-free frosting, a homolog of SAD kinase, drives neural-specific glycan expression in the Drosophila embryo
Q52567086Super-resolution imaging of Drosophila tissues using expansion microscopy.
Q42116692Super-resolution microscopy of the synaptic active zone
Q58727037Suppression of the synaptic localization of a subset of proteins including APP partially ameliorates phenotypes of the Drosophila Alzheimer's disease model
Q98188948Synapse development and maturation at the drosophila neuromuscular junction
Q52717348Synapse loss in olfactory local interneurons modifies perception.
Q38363518Synapsin is required to "boost" memory strength for highly salient events.
Q34354691Synapsin regulates activity-dependent outgrowth of synaptic boutons at the Drosophila neuromuscular junction
Q38826340Synaptic Vesicle Proteins and Active Zone Plasticity.
Q30573528Synaptic abnormalities in a Drosophila model of Alzheimer's disease
Q42237562Synaptic bouton properties are tuned to best fit the prevailing firing pattern
Q40094079Synaptic circuitry of identified neurons in the antennal lobe of Drosophila melanogaster.
Q48514867Synaptic connections of first-stage visual neurons in the locust Schistocerca gregaria extend evolution of tetrad synapses back 200 million years.
Q46667133Synaptic defects in a Drosophila model of congenital muscular dystrophy.
Q35794160Synaptic homeostasis is consolidated by the cell fate gene gooseberry, a Drosophila pax3/7 homolog
Q51889616Synaptic organization in the adult Drosophila mushroom body calyx.
Q34326118Synaptic organization of the Drosophila antennal lobe and its regulation by the Teneurins
Q35225285Synergistic interactions between Drosophila orthologues of genes spanned by de novo human CNVs support multiple-hit models of autism
Q48985796TALE-class homeodomain transcription factors, homothorax and extradenticle, control dendritic and axonal targeting of olfactory projection neurons in the Drosophila brain
Q35171147Terminal axonal arborization and synaptic bouton formation critically rely on abp1 and the arp2/3 complex
Q27301039The Amino Acid Transporter JhI-21 Coevolves with Glutamate Receptors, Impacts NMJ Physiology, and Influences Locomotor Activity in Drosophila Larvae
Q47072136The B' protein phosphatase 2A regulatory subunit well-rounded regulates synaptic growth and cytoskeletal stability at the Drosophila neuromuscular junction.
Q30543185The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles
Q92999298The Conserved IgSF9 Protein Borderless Regulates Axonal Transport of Presynaptic Components and Color Vision in Drosophila
Q41013910The Drosophila KIF1A Homolog unc-104 Is Important for Site-Specific Synapse Maturation
Q37135641The Drosophila SK channel (dSK) contributes to photoreceptor performance by mediating sensitivity control at the first visual network
Q37771032The Drosophila larval neuromuscular junction as a model for scaffold complexes at glutamatergic synapses: benefits and limitations
Q36900646The Extracellular-Regulated Kinase Effector Lk6 is Required for Glutamate Receptor Localization at the Drosophila Neuromuscular Junction
Q35111422The GTPase Rab26 links synaptic vesicles to the autophagy pathway
Q39739973The Ig cell adhesion molecule Basigin controls compartmentalization and vesicle release at Drosophila melanogaster synapses
Q42314260The KIF1A homolog Unc-104 is important for spontaneous release, postsynaptic density maturation and perisynaptic scaffold organization.
Q51958352The L1-CAM, Neuroglian, functions in glial cells for Drosophila antennal lobe development.
Q47734916The Long 3'UTR mRNA of CaMKII Is Essential for Translation-Dependent Plasticity of Spontaneous Release in Drosophila melanogaster
Q47070217The Ly6 neurotoxin-like molecule target of wit regulates spontaneous neurotransmitter release at the developing neuromuscular junction in Drosophila.
Q40116052The Matrix Proteins Hasp and Hig Exhibit Segregated Distribution within Synaptic Clefts and Play Distinct Roles in Synaptogenesis
Q89619702The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons
Q36421459The Notch ligand E3 ligase, Mind Bomb1, regulates glutamate receptor localization in Drosophila.
Q37091646The Osa-containing SWI/SNF chromatin-remodeling complex regulates stem cell commitment in the adult Drosophila intestine
Q35812989The ROP vesicle release factor is required in adult Drosophila glia for normal circadian behavior
Q47070321The RhoGAP crossveinless-c interacts with Dystrophin and is required for synaptic homeostasis at the Drosophila neuromuscular junction.
Q42292318The Role of Histone Deacetylase 6 in Synaptic Plasticity and Memory
Q21284243The Virtual Insect Brain protocol: creating and comparing standardized neuroanatomy
Q33398576The Wuerzburg hybridoma library against Drosophila brain
Q37765592The active zone T-bar--a plasticity module?
Q26269841The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons
Q36803738The anatomical basis for modulatory convergence in the antennal lobe of Manduca sexta
Q92469487The astrocyte network in the ventral nerve cord neuropil of the Drosophila third-instar larva
Q35830186The atypical cadherin flamingo regulates synaptogenesis and helps prevent axonal and synaptic degeneration in Drosophila.
Q91767495The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
Q36882863The cell polarity scaffold Lethal Giant Larvae regulates synapse morphology and function
Q90776110The depletion of ubiquilin in Drosophila melanogaster disturbs neurochemical regulation to drive activity and behavioral deficits
Q30009943The dynamin-binding domains of Dap160/intersectin affect bulk membrane retrieval in synapses
Q38784541The dystrophin Dp186 isoform regulates neurotransmitter release at a central synapse in Drosophila.
Q41367348The equilibrium between antagonistic signaling pathways determines the number of synapses in Drosophila.
Q47071411The foraging gene of Drosophila melanogaster: spatial-expression analysis and sucrose responsiveness
Q34994645The golgin coiled-coil proteins of the Golgi apparatus
Q30544013The kinesin-3, unc-104 regulates dendrite morphogenesis and synaptic development in Drosophila
Q44912296The matrix protein Hikaru genki localizes to cholinergic synaptic clefts and regulates postsynaptic organization in the Drosophila brain.
Q91011950The neuronal ceroid lipofuscinosis protein Cln7 functions in the postsynaptic cell to regulate synapse development
Q33717079The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation.
Q42569845The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling.
Q26269863The presynaptic active zone
Q33853608The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD-2/liprin and UNC-10/RIM-dependent interactions
Q38950913The role of laminins in the organization and function of neuromuscular junctions
Q24632783The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis
Q37361247The translational repressors Nanos and Pumilio have divergent effects on presynaptic terminal growth and postsynaptic glutamate receptor subunit composition
Q34392850Three Drosophila liprins interact to control synapse formation
Q34642485Three-dimensional architecture of presynaptic terminal cytomatrix.
Q35638818Tiling among stereotyped dendritic branches in an identified Drosophila motoneuron
Q36084776Tip60 HAT Action Mediates Environmental Enrichment Induced Cognitive Restoration
Q38807732Tissue-specific transcription of the neuronal gene Lim3 affects Drosophila melanogaster lifespan and locomotion
Q47989635Topological and modality-specific representation of somatosensory information in the fly brain
Q35888419Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice.
Q36132208Transmission, Development, and Plasticity of Synapses.
Q36669876Transmitter release at the neuromuscular junction
Q30370750Tricornered Kinase Regulates Synapse Development by Regulating the Levels of Wiskott-Aldrich Syndrome Protein
Q64979823Tubulin Polymerization Promoting Protein, Ringmaker, and MAP1B Homolog Futsch Coordinate Microtubule Organization and Synaptic Growth.
Q47071725Two Components of Aversive Memory in Drosophila, Anesthesia-Sensitive and Anesthesia-Resistant Memory, Require Distinct Domains Within the Rgk1 Small GTPase.
Q36497245Two classes of matrix metalloproteinases reciprocally regulate synaptogenesis
Q34233422Two protein N-acetylgalactosaminyl transferases regulate synaptic plasticity by activity-dependent regulation of integrin signaling
Q33708223USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin
Q45072444Ultra-selective looming detection from radial motion opponency
Q34583584Ultrafast tissue staining with chemical tags.
Q46017511Ultrastructural analysis of chemical synapses and gap junctions between Drosophila brain neurons in culture.
Q48230340Ultrastructural comparison of the Drosophila larval and adult ventral abdominal neuromuscular junction.
Q37341799Unc-51 controls active zone density and protein composition by downregulating ERK signaling
Q39420011Vertebrate Presynaptic Active Zone Assembly: a Role Accomplished by Diverse Molecular and Cellular Mechanisms
Q37626721Visual projection neurons in the Drosophila lobula link feature detection to distinct behavioral programs
Q30489066Widespread changes in synaptic markers as a function of sleep and wakefulness in Drosophila
Q89506084Wiring patterns from auditory sensory neurons to the escape and song-relay pathways in fruit flies
Q42261303Wnt5 and drl/ryk gradients pattern the Drosophila olfactory dendritic map.
Q42373211cAMP Signals in Drosophila Motor Neurons Are Confined to Single Synaptic Boutons.
Q92617593cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis
Q34064374dTip60 HAT activity controls synaptic bouton expansion at the Drosophila neuromuscular junction
Q88789088t-GRASP, a targeted GRASP for assessing neuronal connectivity

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