Ligand-gated ion channels in the brain: the amino acid receptor superfamily

scientific article published on October 1990

Ligand-gated ion channels in the brain: the amino acid receptor superfamily is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/0896-6273(90)90077-S
P698PubMed publication ID1698394

P2093author name stringBetz H
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)383-392
P577publication date1990-10-01
P1433published inNeuronQ3338676
P1476titleLigand-gated ion channels in the brain: the amino acid receptor superfamily
P478volume5

Reverse relations

cites work (P2860)
Q30492719A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response
Q71538994ABT-418: discriminative stimulus properties and effect on ventral tegmental cell activity
Q41524934Agonist pharmacology of neonatal and adult glycine receptor alpha subunits: identification of amino acid residues involved in taurine activation
Q53017950All potential glycosylation sites of the nicotinic acetylcholine receptor delta subunit from Torpedo californica are utilized.
Q28363101Allosteric modulation of [3H]-CGP39653 binding through the glycine site of the NMDA receptor: further studies in rat and human brain
Q53858592Altered glycosylation sites of the delta subunit of the acetylcholine receptor (AChR) reduce alpha delta association and receptor assembly.
Q49130656Amino acids lining the channel of the gamma-aminobutyric acid type A receptor identified by cysteine substitution
Q55920981Assembly of the Nicotinic Acetylcholine Receptor
Q52097916Binding site opening by loop C shift and chloride ion-pore interaction in the GABAA receptor model.
Q40700542Binding site stoichiometry and the effects of phosphorylation on human alpha1 homomeric glycine receptors.
Q51500659Binding sites for exogenous and endogenous non-competitive inhibitors of the nicotinic acetylcholine receptor.
Q48922658Blue native PAGE as a useful method for the analysis of the assembly of distinct combinations of nicotinic acetylcholine receptor subunits
Q57861107Chapter 16 GABAA- and GABAB-mediated processes in visual cortex
Q48048332Chick ciliary ganglion neurons contain transcripts coding for acetylcholine receptor-associated protein at synapses (rapsyn).
Q51580747Chimeric GABAA/glycine receptors: expression and barbiturate pharmacology.
Q40161257Chloride channels of glycine and GABA receptors with blockers: Monte Carlo minimization and structure-activity relationships
Q48068516Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel.
Q39396341Cobalt accumulation in neurons expressing ionotropic excitatory amino acid receptors in young rat spinal cord: morphology and distribution
Q36890979Collateral projections from striatonigral neurons to substance P receptor-expressing intrinsic neurons in the striatum of the rat.
Q48649859Conservation of antigenic epitopes of the inhibitiory glycine receptor in rodent and goldfish CNS
Q44639270Conserved High Affinity Ligand Binding and Membrane Association in the Native and Refolded Extracellular Domain of the Human Glycine Receptor α1-Subunit
Q33649945Contribution of P2X4 receptors to ethanol intake in male C57BL/6 mice
Q44560510Corpus callosum and visual cortex of mice with deletion of the NMDA-NR1 receptor. II. Attenuation of prenatal alcohol exposure effects
Q44560506Corpus callosum and visual cortex of mice with deletion of the NMDA-NR1 receptor: I. Accelerated development of callosal projection neurons
Q34170761Coupling of agonist binding to channel gating in the GABA(A) receptor
Q24634206Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes
Q48345565Cultured oligodendrocyte progenitors derived from cerebral cortex express a glycine receptor which is pharmacologically distinct from the neuronal isoform.
Q38362079Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels
Q32055083Development and application of caged ligands for neurotransmitter receptors in transient kinetic and neuronal circuit mapping studies
Q36386508Diversity in receptor signalling: cellular individuality and the search for selective drugs
Q44264530Dual cooperative allosteric modulation of binding to ionotropic glycine receptors
Q34542555EXP-1 is an excitatory GABA-gated cation channel
Q41062053Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267.
Q33767770Ethanol actions on multiple ion channels: which are important?
Q33426923Ethanol potentiation of glycine receptors expressed in Xenopus oocytes antagonized by increased atmospheric pressure
Q44030560Ethanol sensitivity in ATP-gated P2X receptors is subunit dependent
Q37630015Expression of the human glycine receptor alpha 1 subunit in Xenopus oocytes: apparent affinities of agonists increase at high receptor density
Q28275121Extracellular domains mediating epsilon subunit interactions of muscle acetylcholine receptor
Q41986225Extrasynaptic and postsynaptic receptors in glycinergic and GABAergic neurotransmission: a division of labor?
Q34331963Fast kinetic analysis of ligand-gated ion channels
Q34229539Focal and secondarily generalised convulsive status epilepticus induced by thiocolchicoside in the rat.
Q40386612Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels
Q40453946Functional domains of GABAA receptors.
Q31807464Functional reconstitution and characterization of recombinant human alpha 1-glycine receptors
Q34305669GABA Receptor molecules of insects
Q28198053GABA and GABA receptors in the central nervous system and other organs
Q42664010GABA(A) receptor beta 2 Tyr97 and Leu99 line the GABA-binding site. Insights into mechanisms of agonist and antagonist actions
Q40457385GABAA/Benzodiazepine receptor heterogeneity: Neurophysiological implications
Q37282736Glutamate receptors of Drosophila melanogaster: cloning of a kainate-selective subunit expressed in the central nervous system
Q48082303Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion.
Q28588996Glycine receptors containing the alpha4 subunit in the embryonic sympathetic nervous system, spinal cord and male genital ridge
Q72751014Glycine receptors: a startling connection
Q36708261Glycine receptors: heterogeneous and widespread in the mammalian brain
Q73055863Glycine-activated whole cell and single channel currents in rat cerebellar granule cells in culture
Q49124802Glycine-glutamate interactions at the NMDA receptor: role of cysteine residues
Q41707937Heritable mutations in the glycine, GABAA, and nicotinic acetylcholine receptors provide new insights into the ligand-gated ion channel receptor superfamily.
Q28182183Heteromeric NMDA receptors: molecular and functional distinction of subtypes
Q24671348High-resolution mapping of the gamma-aminobutyric acid receptor subunit beta 3 and alpha 5 gene cluster on chromosome 15q11-q13, and localization of breakpoints in two Angelman syndrome patients
Q33863107Homology modeling and molecular dynamics simulations of the glycine receptor ligand binding domain
Q44068286Hyperekplexia mutation of glycine receptors: decreased gating efficacy with altered binding thermodynamics
Q73191219Immunocytochemical localization of the GABA(C) receptor rho subunits in the cat, goldfish, and chicken retina
Q31125798In vitro interaction of the glycine receptor with the leptin receptor
Q28298707Intersubunit contacts governing assembly of the mammalian nicotinic acetylcholine receptor
Q40147171Investigation of the alpha(1)-glycine receptor channel-opening kinetics in the submillisecond time domain
Q48461126Kinetic analysis of glycine receptor currents in ventral cochlear nucleus.
Q40627198Kinetic analysis of recombinant mammalian alpha(1) and alpha(1)beta glycine receptor channels.
Q47987466Kinetics of sevoflurane action on GABA- and glycine-induced currents in acutely dissociated rat hippocampal neurons
Q52213586Localization and developmental expression of the NMDA receptor subunit NR2A in the mammalian retina.
Q52053703Localization of NMDA receptor subunit mRNAs in the rat locus coeruleus
Q36558167Mechanism of generation of spontaneous miniature outward currents (SMOCs) in retinal amacrine cells
Q30341434Mechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure.
Q36237628Membrane tethering enables an extracellular domain of the acetylcholine receptor alpha subunit to form a heterodimeric ligand-binding site
Q74432742Mode switching kinetics produced by a naturally occurring mutation in the cytoplasmic loop of the human acetylcholine receptor epsilon subunit
Q38295606Modulation of 5-HT3 receptor desensitization by the light chain of microtubule-associated protein 1B expressed in HEK 293 cells
Q36459451Modulation of nicotinic acetylcholine receptors by strychnine
Q40484471Molecular analysis of Drosophila glutamate receptors
Q36708223Molecular analysis of neuronal physiology by gene transfer into neurons with herpes simplex virus vectors
Q41460097Molecular characterization of NMDA and metabotropic glutamate receptors
Q34762781Molecular cloning and characterization of the rat NMDA receptor
Q36592567Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of residues that determine curare selectivity
Q46454812Mutations in the M1 region of the nicotinic acetylcholine receptor alter the sensitivity to inhibition by quinacrine
Q42617071Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor
Q50789819Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic.
Q37508589Mysterious alpha6-containing nAChRs: function, pharmacology, and pathophysiology
Q51624324Neuroactive steroids modulate GABAA receptors in peptidergic nerve terminals.
Q40444459Neuronal Nicotinic Receptor Subtypes
Q33687197Neuronal nicotinic acetylcholine receptors: a new target site of ethanol
Q35580605Neurosteroids, GABAA receptors, and escalated aggressive behavior
Q39419222Neurotransmitter receptors as signaling platforms in anterior pituitary cells.
Q52353173New tricks for old dogs: improving the accuracy of biomolecular force fields by pair-specific corrections to non-bonded interactions.
Q41330522Nicotinic acetylcholine receptors on hippocampal neurons: cell compartment-specific expression and modulatory control of channel activity.
Q28512079Nmf11 is a novel ENU-induced mutation in the mouse glycine receptor alpha 1 subunit
Q33207428Noninvasive imaging of 5-HT3 receptor trafficking in live cells: from biosynthesis to endocytosis.
Q24291969Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B
Q40485207O2 deprivation in the central nervous system: On mechanisms of neuronal response, differential sensitivity and injury
Q83227438ON selectivity in the visual system is a multisynaptic process involving both glutamatergic and GABAergic inhibition
Q34320153Ondansetron: a selective 5-HT(3) receptor antagonist and its applications in CNS-related disorders.
Q24533248P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels
Q27021285P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disorders
Q35870575Penicillin-induced potentiation of glycine receptor-operated chloride current in rat ventro-medial hypothalamic neurones
Q34536543Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosine
Q34042985Photolabeling reveals the proximity of the alpha-neurotoxin binding site to the M2 helix of the ion channel in the nicotinic acetylcholine receptor.
Q34116031Pore conformations and gating mechanism of a Cys-loop receptor
Q37385244Presence of multiple binding sites on α9α10 nAChR receptors alludes to stoichiometric-dependent action of the α-conotoxin, Vc1.1.
Q28587413Primary structure and expression of the γ2 subunit of the glutamate receptor channel selective for kainate
Q33267111Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel
Q48371155Prolonged noxious stimulation increases periaqueductal gray NMDA mRNA expression: a hybridization study using two different rat models for nociception
Q30481350Protons act as a transmitter for muscle contraction in C. elegans
Q73575691Receptor binding characteristics of the novel NMDA receptor glycine site antagonist [3H]GV150526A in rat cerebral cortical membranes
Q36723608Receptors coupled to ionic channels: the glutamate receptor family
Q30336137Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor.
Q46368164Sequences on the N-terminus of ACh receptor subunits regulate their assembly
Q44201717Serotonin 5-HT(3) receptors in rat CA1 hippocampal interneurons: functional and molecular characterization
Q48055229Side chain flexibility and the pore dimensions in the GABAA receptor.
Q41227277Stable expression of insect GABA receptors in insect cell lines. Promoters for efficient expression of Drosophila and mosquito Rdl GABA receptors in stably transformed mosquito cell lines.
Q24563145Stimulation of ionotropic glutamate receptors activates transcription factor NF-kappa B in primary neurons
Q37226718Stoichiometric analysis of the TM2 6' phenylalanine mutation on desensitization in alpha1beta2 and alpha1beta2gamma2 GABA A receptors
Q41460071Structure and biology of inhibitory glycine receptors
Q35168987Structure and function of inhibitory glycine receptors
Q33691545Structure and functions of inhibitory and excitatory glycine receptors.
Q26852212Structure and pharmacology of pentameric receptor channels: from bacteria to brain
Q67765281Structure of the agonist-binding site of the nicotinic acetylcholine receptor. [3H]acetylcholine mustard identifies residues in the cation-binding subsite
Q26859328Structure, function, and modulation of GABA(A) receptors
Q53794394Synaptic control of glycine and GABA(A) receptors and gephyrin expression in cultured motoneurons.
Q37974718Synaptic neurotransmitter-gated receptors
Q44830270Taurine and glycine activate the same Cl− conductance in substantia nigra dopamine neurones
Q45910985The 93 kDa protein gephyrin and tubulin associated with the inhibitory glycine receptor are phosphorylated by an endogenous protein kinase
Q57258805The Evolution of GABAA Receptor–Like Genes
Q40484660The GABAA receptor channel mediated chloride ion translocation through the plasma membrane: New insights from 36Cl− ion flux measurements
Q28316466The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels
Q44102180The beta subunit determines the ion selectivity of the GABAA receptor
Q28188947The chaperone protein 14-3-3eta interacts with the nicotinic acetylcholine receptor alpha 4 subunit. Evidence for a dynamic role in subunit stabilization
Q34481002The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes
Q30424904The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor
Q44114979The general anesthetic pentobarbital slows desensitization and deactivation of the glycine receptor in the rat spinal dorsal horn neurons
Q34297102The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex
Q40643643The inhibitory neuronal glycine receptor.
Q40491021The kinetic properties of neuronal nicotinic receptors: Genetic basis of functional diversity
Q44333468The opioid antagonist naltrexone inhibits activity and alters expression of alpha7 and alpha4beta2 nicotinic receptors in hippocampal neurons: implications for smoking cessation programs
Q44340357The organochlorine pesticides gamma-hexachlorocyclohexane (lindane), alpha-endosulfan and dieldrin differentially interact with GABA(A) and glycine-gated chloride channels in primary cultures of cerebellar granule cells
Q35779254The therapeutic potential of glycine transporter-1 inhibitors
Q40487597The unique properties of glutamate receptor channels
Q43507092Two conserved arginines in the extracellular N-terminal domain of the GABA(A) receptor alpha(5) subunit are crucial for receptor function
Q30355589Voltage-Dependent Inhibition of Glycine Receptor Channels by Niflumic Acid
Q80610004WITHDRAWN: Inhibitory effects of D-Serine on hippocampal synapse transmission
Q41165809Whole-cell and single-channel alpha1 beta1 gamma2S GABAA receptor currents elicited by a "multipuffer" drug application device
Q41081995Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain
Q43867599Yeast expression and NMR analysis of the extracellular domain of muscle nicotinic acetylcholine receptor alpha subunit