scholarly article | Q13442814 |
P2093 | author name string | Lawrence Chan | |
Benny Hung-Junn Chang | |||
Yisheng Yang | |||
P2860 | cites work | Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion | Q36733461 |
Glucolipotoxicity: fuel excess and beta-cell dysfunction. | Q36861036 | ||
Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion | Q37214986 | ||
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function | Q37238979 | ||
Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression | Q37452586 | ||
Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. | Q40051311 | ||
Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion | Q40871524 | ||
IPF1, a homeodomain-containing transactivator of the insulin gene | Q40874284 | ||
A murine model of neonatal diabetes mellitus in Glis3-deficient mice | Q42454563 | ||
Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people | Q43085753 | ||
Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism. | Q48087598 | ||
mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor | Q56871535 | ||
Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter | Q73473642 | ||
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes | Q24632382 | ||
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Q28270700 | ||
The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription | Q28507859 | ||
Rat endocrine pancreatic development in relation to two homeobox gene products (Pdx-1 and Nkx 6.1) | Q28570676 | ||
GLIS3, a novel member of the GLIS subfamily of Kruppel-like zinc finger proteins with repressor and activation functions | Q28591478 | ||
Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes | Q28744684 | ||
Pancreatic beta cells require NeuroD to achieve and maintain functional maturity | Q28752551 | ||
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians | Q29417142 | ||
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum | Q29618151 | ||
Insulin-promoter-factor 1 is required for pancreas development in mice | Q29619695 | ||
Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents | Q33750760 | ||
Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats | Q33757675 | ||
Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth | Q33758338 | ||
Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans | Q33957907 | ||
Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity | Q34109834 | ||
Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein. | Q34114554 | ||
Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children | Q35043398 | ||
The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice. | Q35252235 | ||
Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes | Q35641724 | ||
Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas | Q35796459 | ||
Five stages of evolving beta-cell dysfunction during progression to diabetes | Q35961960 | ||
Pancreatic beta cells express a diverse set of homeobox genes | Q35967171 | ||
Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors | Q36056970 | ||
Molecular control of cell cycle progression in the pancreatic beta-cell | Q36459964 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 1 | |
P921 | main subject | cell function | Q95674809 |
P1104 | number of pages | 13 | |
P304 | page(s) | 92-104 | |
P577 | publication date | 2012-11-29 | |
P1433 | published in | EMBO Molecular Medicine | Q15817279 |
P1476 | title | Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults | |
P478 | volume | 5 |
Q90167406 | A GLIS3-CD133-WNT-signaling axis regulates the self-renewal of adult murine pancreatic progenitor-like cells in colonies and organoids |
Q27314498 | A genetic strategy to measure circulating Drosophila insulin reveals genes regulating insulin production and secretion |
Q92256221 | ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes |
Q90745613 | Advances in Knowledge of Candidate Genes Acting at the Beta-Cell Level in the Pathogenesis of T1DM |
Q57915591 | An emerging, recognizable facial phenotype in association with mutations in GLI-similar 3 (GLIS3) |
Q38134106 | Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis |
Q51344557 | Differential Gene Dosage Effects of Diabetes-Associated Gene GLIS3 in Pancreatic β Cell Differentiation and Function. |
Q58705850 | Discovering human diabetes-risk gene function with genetics and physiological assays |
Q61136989 | Discovery of a drug candidate for GLIS3-associated diabetes |
Q33726975 | Drosophila as a Model for Diabetes and Diseases of Insulin Resistance |
Q35123257 | Elevation of NR4A3 expression and its possible role in modulating insulin expression in the pancreatic beta cell |
Q36129829 | Expanding the Clinical Spectrum Associated With GLIS3 Mutations |
Q36295781 | Extended clinical features associated with novel Glis3 mutation: a case report. |
Q88738703 | GLIS1-3 transcription factors: critical roles in the regulation of multiple physiological processes and diseases |
Q47618990 | GLIS1-3: emerging roles in reprogramming, stem and progenitor cell differentiation and maintenance. |
Q47588788 | GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation. |
Q48596938 | GLIS3 rs7020673 and rs10758593 polymorphisms interact in the susceptibility for type 1 diabetes mellitus. |
Q28571413 | GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim |
Q38590582 | Genes affecting β-cell function in type 1 diabetes |
Q35683842 | HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity. |
Q64944288 | Identification of placental genes linked to selective intrauterine growth restriction (IUGR) in dichorionic twin pregnancies: gene expression profiling study. |
Q36422024 | Long noncoding RNAs in diseases of aging |
Q55426195 | Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis. |
Q33622236 | Many faces of monogenic diabetes |
Q50084245 | Molecular genetics of the transcription factor GLIS3 identifies its dual function in beta cells and neurons |
Q36960085 | Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes |
Q38531169 | Pancreatic islet cell development and regeneration |
Q34040124 | TRANSCRIPTION FACTOR GLI-SIMILAR 3 (GLIS3): IMPLICATIONS FOR THE DEVELOPMENT OF CONGENITAL HYPOTHYROIDISM. |
Q37207625 | The Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription. |
Q36043191 | The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells |
Q37537864 | The pancreatic β cell and type 1 diabetes: innocent bystander or active participant? |
Q41611533 | Transcription Factor GLIS3: A New and Critical Regulator of Postnatal Stages of Mouse Spermatogenesis. |
Q28083955 | Transcription factor regulation of pancreatic organogenesis, differentiation and maturation |
Q39140831 | Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis |
Q49200841 | Type 1 diabetes genome-wide association studies: not to be lost in translation |