B cell development and immunoglobulin transcription in Oct-1-deficient mice

scholarly article

B cell development and immunoglobulin transcription in Oct-1-deficient mice is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2004PNAS..101.2005W
P356DOI10.1073/PNAS.0307304101
P932PMC publication ID357042
P698PubMed publication ID14762167
P5875ResearchGate publication ID8887216

P2093author name stringJianzhu Chen
Phillip A Sharp
Dean Tantin
Victoria E H Wang
P2860cites workOBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteinsQ24313516
Identification of target genes of the lymphoid-specific transcription factor Oct2Q24323193
The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locusQ24647015
Mini-Oct and Oct-2c: two novel, functionally diverse murine Oct-2 gene products are differentially expressed in the CNSQ48517170
Oct-2 is required early in T cell-independent B cell activation for G1 progression and for proliferationQ51130519
oct-2 gene disruption eliminates the peritoneal B-1 lymphocyte lineage and attenuates B-2 cell maturation and function.Q52530201
Interaction and functional interference of C/EBPbeta with octamer factors in immunoglobulin gene transcription.Q52975347
A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cellsQ58989803
A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox proteinQ58989818
The POU domain is a bipartite DNA-binding structureQ58990231
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genesQ59066385
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genesQ59067785
Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elementsQ59070373
An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activityQ59094880
The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypesQ59098629
Nuclear factor III, a novel sequence-specific DNA-binding protein from HeLa cells stimulating adenovirus DNA replicationQ64380062
Binding of transcription factors to the promoter of the human U1 RNA gene studied by footprintingQ67955799
Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcriptionQ69230362
Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequenceQ69942457
B lymphocytes are impaired in mice lacking the transcriptional co-activator Bob1/OCA-B/OBF1Q71930373
Transcriptional regulation during B cell developmentQ74578122
Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-BQ24651545
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domainsQ28114875
OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin kappa genesQ28201794
Inducible Expression and Phosphorylation of Coactivator BOB.1/OBF.1 in T CellsQ28242912
A B-cell coactivator of octamer-binding transcription factorsQ28303069
Oct-2 regulates CD36 gene expression via a consensus octamer, which excludes the co-activator OBF-1.Q28504942
The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitroQ28506364
Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survivalQ28513024
RAG-1-deficient mice have no mature B and T lymphocytesQ28592133
The conserved decanucleotide from the immunoglobulin heavy chain promoter induces a very high transcriptional activity in B-cells when introduced into an heterologous promoterQ33929182
p53 mediates apoptotic crisis in primary Abelson virus-transformed pre-B cellsQ33958575
Multiple DNA sequence elements are necessary for the function of an immunoglobulin heavy chain promoterQ34359857
Structure of the 5' ends of immunoglobulin genes: a novel conserved sequenceQ36258756
RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte developmentQ36303172
Cloning of a Lymphoid-Specific cDNA Encoding a Protein Binding the Regulatory Octamer DNA MotifQ36454242
The promoter of the human interleukin-2 gene contains two octamer-binding sites and is partially activated by the expression of Oct-2.Q36729328
Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B geneQ36897138
Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genesQ37396956
Mutational analysis of the immunoglobulin heavy chain promoter regionQ37411997
A family of POU-domain and Pit-1 tissue-specific transcription factors in pituitary and neuroendocrine developmentQ37918975
Identification of CD36 as the first gene dependent on the B-cell differentiation factor Oct-2.Q38293977
Involvement of the Ets family factor PU.1 in the activation of immunoglobulin promotersQ38299790
Octamer factors exert a dual effect on the IL-2 and IL-4 promotersQ38301252
B cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1.Q38302908
Positive and negative regulation of IL-2 gene expression: role of multiple regulatory sitesQ38308608
Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.Q38321834
Identification of sites for distinct DNA binding proteins including Oct-1 and Oct-2 in the Cr2 geneQ38328381
Embryonic lethality, decreased erythropoiesis, and defective octamer-dependent promoter activation in Oct-1-deficient mice.Q40468947
Targeted disruption of the Oct-2 locus in a B cell provides genetic evidence for two distinct cell type-specific pathways of octamer element-mediated gene activationQ40873369
Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus.Q40875075
Transcriptional regulation of the murine 3' IgH enhancer by OCT-2.Q40913230
Octamer-binding proteins from B or HeLa cells stimulate transcription of the immunoglobulin heavy-chain promoter in vitroQ41424983
The DNA binding specificity of the bipartite POU domain and its subdomainsQ41543532
Cell type- and stage-specific expression of the CD20/B1 antigen correlates with the activity of a diverged octamer DNA motif present in its promoterQ41566088
Complex pattern of immunoglobulin mu gene expression in normal and transgenic mice: nonoverlapping regulatory sequences govern distinct tissue specificitiesQ42472717
Cloning and analysis of the human Pax-5 gene promoterQ42526804
The variable genes and gene families of the mouse immunoglobulin kappa locusQ47942088
B cell development under the condition of allelic inclusion.Q48053216
Targeted insertion of a variable region gene into the immunoglobulin heavy chain locusQ48091786
Transcription of a gene for human U1 small nuclear RNA.Q48404894
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)2005-2010
P577publication date2004-02-04
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleB cell development and immunoglobulin transcription in Oct-1-deficient mice
P478volume101

Reverse relations

cites work (P2860)
Q28755336A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress
Q34468275A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory
Q33271202Characterization of an Oct1 orthologue in the channel catfish, Ictalurus punctatus: a negative regulator of immunoglobulin gene transcription?
Q87953442Collaborative interaction of Oct-2 with Oct-1 in transactivation of lactogenic hormones-induced β-casein gene expression in mammary epithelial cells
Q36799525Dynamic regulatory network controlling TH17 cell differentiation
Q33229483Identification of novel genes and transcription factors involved in spleen, thymus and immunological development and function
Q42482263NF-κB-dependent signals control BOB.1/OBF.1 and Oct2 transcriptional activity in B cells
Q39021104OCT-1 overexpression is associated with poor prognosis in patients with well-differentiated gastric cancer
Q34818674OCT1 is a determinant of synbindin-related ERK signalling with independent prognostic significance in gastric cancer
Q40168015Oct-1 is involved in the transcriptional repression of the p15(INK4b) gene
Q40723195Oct-1 regulates IL-17 expression by directing interchromosomal associations in conjunction with CTCF in T cells
Q34452605Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states.
Q46121299Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity.
Q56492140Octamer transcription factor 1 mediates epithelial-mesenchymal transition in colorectal cancer
Q38112991Octamer-binding transcription factors: genomics and functions
Q42073832Octamer-dependent transcription in T cells is mediated by NFAT and NF-κB.
Q24806088Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals
Q38323522Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.
Q34980070The Oct1 homolog Nubbin is a repressor of NF-κB-dependent immune gene expression that increases the tolerance to gut microbiota
Q36936127The Oct1 transcription factor and epithelial malignancies: Old protein learns new tricks
Q80611324The POU homeobox protein Oct-1 regulates radial glia formation downstream of Notch signaling
Q34097069The POU transcription factor Oct-1 represses virus-induced interferon A gene expression
Q34473592Transcription factor Oct1 is a somatic and cancer stem cell determinant
Q36146925Transcriptional networks in developing and mature B cells

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