The Influence of DNA Methylation on Bone Cells.

scientific article published on December 2015

The Influence of DNA Methylation on Bone Cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2174/1389202916666150817202913
P932PMC publication ID4765525
P698PubMed publication ID27019613

P50authorSjur ReppeQ68084667
P2093author name stringKaare M Gautvik
Harish Datta
P2860cites workCross-talk between site-specific transcription factors and DNA methylation statesQ26860809
Extracellular modulators of Wnt signallingQ27013685
Regulation of NFATc1 in Osteoclast DifferentiationQ27021109
CpG islands in vertebrate genomesQ27861045
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signalingQ28240767
Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesisQ28267970
WNT signaling in bone homeostasis and disease: from human mutations to treatmentsQ28285090
Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibodyQ28286616
Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in boneQ28303536
CpG islands and the regulation of transcriptionQ28315762
Mechanical loading in osteocytes induces formation of a Src/Pyk2/MBD2 complex that suppresses anabolic gene expressionQ28584740
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in miceQ29547898
Skeletal site-related variation in human trabecular bone transcriptome and signalingQ33587526
Epigenetic modifications and canonical wingless/int-1 class (WNT) signaling enable trans-differentiation of nonosteogenic cells into osteoblastsQ33931182
Epigenetic regulation of alkaline phosphatase in human cells of the osteoblastic lineageQ33941640
Methylation status of a single CpG locus 3 bases upstream of TATA-box of receptor activator of nuclear factor-kappaB ligand (RANKL) gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis.Q51583721
Methylation of BoneSOST, Its mRNA, and Serum Sclerostin Levels Correlate Strongly With Fracture Risk in Postmenopausal WomenQ57250831
Epigenetic control of mouse receptor activator of NF-κB ligand gene expressionQ58008571
Promoter structure of mouse RANKL/TRANCE/OPGL/ODF geneQ58008649
Sclerostin antibody treatment enhances metaphyseal bone healing in ratsQ63248242
Bone mass, lean mass, and fat mass: same genes or same environments?Q74081653
Mechanical loading by fluid shear stress enhances IGF-1 receptor signaling in osteoblasts in a PKCzeta-dependent mannerQ81320678
Genetics of osteoporosisQ84134341
Developing new chemical tools for DNA methyltransferase 1 (DNMT 1): a small-molecule activity-based probe and novel tetrazole-containing inhibitorsQ86978531
Active DNA demethylation: many roads lead to Rome.Q34129576
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fractureQ34268288
DNA methylation and the regulation of gene transcriptionQ34578086
TET proteins and the control of cytosine demethylation in cancerQ35021377
Dynamics of nucleosome assembly and effects of DNA methylationQ35080335
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.Q35169651
Role of DNA methylation in the regulation of the RANKL-OPG system in human boneQ35916106
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) miceQ36119294
Digging deep into "dirty" drugs - modulation of the methylation machineryQ36523796
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elementsQ37298169
Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesisQ37370702
The mechanism of mineralization and the role of alkaline phosphatase in health and diseaseQ37692049
Intragenic DNA methylation: implications of this epigenetic mechanism for cancer researchQ37968137
Alternative Wnt pathways and receptorsQ38039332
Molecular mechanisms of triggering, amplifying and targeting RANK signaling in osteoclastsQ38074961
Secreted frizzled related proteins: Implications in cancersQ38169447
Eight genes are highly associated with BMD variation in postmenopausal Caucasian womenQ38348789
Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilageQ38475385
Hypoxia mimetic deferoxamine influences the expression of histone acetylation- and DNA methylation-associated genes in osteoblasts.Q38910456
A Sclerostin super-producer cell line derived from the human cell line SaOS-2: a new tool for the study of the molecular mechanisms driving Sclerostin expression.Q38986443
si-DNMT1 restore tumor suppressor genes expression through the reversal of DNA hypermethylation in cholangiocarcinomaQ39041268
Nitric oxide is involved in the down-regulation of SOST expression induced by mechanical loadingQ39045041
Role of BMPs in the regulation of sclerostin as revealed by an epigenetic modifier of human bone cells.Q39193457
DNA methyltransferase 1 is essential for initiation of the colon cancersQ39259783
5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 statusQ39337244
Zic1 transcription factor in bone: neural developmental protein regulates mechanotransduction in osteocytes.Q39720797
The role of promoter CpG methylation in the epigenetic control of stem cell related genes during differentiationQ39883187
Methylation of the mouse DIx5 and Osx gene promoters regulates cell type-specific gene expression.Q40211731
The orphan receptor tyrosine kinase Ror2 modulates canonical Wnt signaling in osteoblastic cellsQ40511859
Methylation analysis of the promoter F of estrogen receptor alpha gene: effects on the level of transcription on human osteoblastic cells.Q40534000
The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblastsQ40594344
PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiationQ40617973
ROR2 Promoter Methylation Change in Osteoblastic Differentiation of Mesenchymal Stem CellsQ40655192
5-Azacytidine facilitates osteogenic gene expression and differentiation of mesenchymal stem cells by alteration in DNA methylationQ41858177
Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylationQ41986504
Stable genetic alterations of β-catenin and ROR2 regulate the Wnt pathway, affect the fate of MSCsQ42233945
The epigenetic mechanism of mechanically induced osteogenic differentiationQ42377008
DNA methylation contributes to the regulation of sclerostin expression in human osteocytes.Q42498840
Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblastsQ42518611
Bone and hormonal changes induced by skeletal unloading in the mature male rat.Q46766812
Wnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcomaQ46789159
Human primary osteocyte differentiation in a 3D culture system.Q47871440
DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine-producing metabolic pathway.Q48222451
Effect of 5-Aza-2'-deoxycytidine on odontogenic differentiation of human dental pulp cells.Q50452396
P433issue6
P921main subjectDNA methylationQ874745
P304page(s)384-392
P577publication date2015-12-01
P1433published inCurrent GenomicsQ5195047
P1476titleThe Influence of DNA Methylation on Bone Cells
P478volume16

Reverse relations

Q89123174Hydrogen sulfide epigenetically mitigates bone loss through OPG/RANKL regulation during hyperhomocysteinemia in micecites workP2860

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