Regulation of NFATc1 in Osteoclast Differentiation

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Regulation of NFATc1 in Osteoclast Differentiation is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.11005/JBM.2014.21.4.233
P3181OpenCitations bibliographic resource ID3060709
P932PMC publication ID4255043
P698PubMed publication ID25489571
P5875ResearchGate publication ID269721624

P2093author name stringNacksung Kim
Jung Ha Kim
P2860cites workEpigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signalsQ22122053
Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stressQ24291525
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1Q24300916
Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3Q24309262
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
RANK is essential for osteoclast and lymph node developmentQ24598872
NFAT: ubiquitous regulator of cell differentiation and adaptationQ24673318
The functions of animal microRNAsQ27860621
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand familiesQ28137631
Bone resorption by osteoclastsQ28145169
Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient miceQ28207641
NFAT signaling: choreographing the social lives of cellsQ28216151
Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathwayQ28255002
Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesisQ28267970
Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1Q28273966
Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systemsQ28294477
Osteoimmunology: interplay between the immune system and bone metabolismQ28303107
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Perceptions of epigeneticsQ29547310
Osteoclast differentiation and activationQ29547556
Signaling to NF-kappaBQ29547844
Missing pieces in the NF-kappaB puzzleQ29547864
The evolution of gene regulation by transcription factors and microRNAsQ29617552
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclastsQ29618116
Transcriptional regulation by calcium, calcineurin, and NFATQ29620410
NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubismQ30157499
NFAT and Osterix cooperatively regulate bone formationQ31813054
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouseQ33646429
Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1.Q33648289
The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.Q33794960
Lhx2 regulates bone remodeling in mice by modulating RANKL signaling in osteoclastsQ34153522
NFAT signaling in vertebrate developmentQ34353096
Requirement for NF-kappaB in osteoclast and B-cell developmentQ35199657
Inactivation of glycogen synthase kinase-3β is required for osteoclast differentiationQ35604256
Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptorQ51049420
Epigenetic regulation of osteoclast differentiation: possible involvement of Jmjd3 in the histone demethylation of Nfatc1.Q51547582
Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.Q52192178
Bone and haematopoietic defects in mice lacking c-fosQ58326969
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor geneQ59092154
Pleiotropic effects of a null mutation in the c-fos proto-oncogeneQ62555352
A role for the p38 MAP kinase pathway in the nuclear shuttling of NFATpQ73731442
Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATcQ74171908
MafB negatively regulates RANKL-mediated osteoclast differentiationQ79421924
Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiationQ35848573
Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulationQ36329898
The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesisQ36371653
I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone lossQ36402985
The role of NFAT in osteoclast formationQ37033696
Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesisQ37370702
The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinaseQ37647341
MicroRNA biogenesis and regulation of bone remodelingQ37884118
Epigenetic regulation of osteoclast differentiation.Q37968675
Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-FosQ38342636
Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient miceQ38359933
RANKL induces NFATc1 acetylation and stability via histone acetyltransferases during osteoclast differentiationQ38476064
PLCgamma2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2.Q38744013
A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1.Q40815624
The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine productionQ41065666
An enhanced immune response in mice lacking the transcription factor NFAT1.Q41199166
Autoamplification of NFATc1 expression determines its essential role in bone homeostasisQ42972503
Expression and regulation of NFAT (nuclear factors of activated T cells) in human CD34+ cells: down-regulation upon myeloid differentiationQ45005986
Inhibition of RANKL-induced osteoclastogenesis by (-)-DHMEQ, a novel NF-kappaB inhibitor, through downregulation of NFATc1.Q46375837
Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesisQ46620740
Calcineurin/NFAT signaling in osteoblasts regulates bone massQ46675973
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasisQ47761859
MicroRNA-124 regulates osteoclast differentiationQ47983185
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)233-41
P577publication date2014-11-01
P1433published inJournal of bone metabolism : JBMQ26853865
P1476titleRegulation of NFATc1 in Osteoclast Differentiation
P478volume21

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cites work (P2860)
Q386978431,25(OH)2 vitamin D(3) contributes to osteoclast-like trans-differentiation of malignant plasma cells.
Q64107402A Novel Small Molecule Which Increases Osteoprotegerin Expression and Protects Against Ovariectomy-Related Bone Loss in Rats
Q92702961A Sub-Clone of RAW264.7-Cells Form Osteoclast-Like Cells Capable of Bone Resorption Faster than Parental RAW264.7 through Increased De Novo Expression and Nuclear Translocation of NFATc1
Q64972623A catalog of single nucleotide changes distinguishing modern humans from archaic hominins.
Q36392181Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1.
Q50065451Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells
Q88361765Alveolar Bone Protective Effect of Hiziki Extracts on the Progression of Periodontitis
Q37377385Amyloid β Peptide Enhances RANKL-Induced Osteoclast Activation through NF-κB, ERK, and Calcium Oscillation Signaling
Q59142520An Overview of Biomaterials in Periodontology and Implant Dentistry
Q89964126Anemonin Attenuates RANKL-Induced Osteoclastogenesis and Ameliorates LPS-Induced Inflammatory Bone Loss in Mice via Modulation of NFATc1
Q90246307Anti-Osteoporotic Effects of Polysaccharides Isolated from Persimmon Leaves via Osteoclastogenesis Inhibition
Q90653768Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL-induced osteoclastogenesis
Q37496714Attenuation of RANKL-induced Osteoclast Formation via p38-mediated NFATc1 Signaling Pathways by Extract of Euphorbia Lathyris L.
Q92187348Beneficial Effects of Total Phenylethanoid Glycoside Fraction Isolated from Cistanche deserticola on Bone Microstructure in Ovariectomized Rats
Q64237120Black Rice ( L.) Fermented with Attenuates Osteoclastogenesis and Ovariectomy-Induced Osteoporosis
Q93108880Bone Remodeling: Histone Modifications as Fate Determinants of Bone Cell Differentiation
Q36265510CD137 Regulates NFATc1 Expression in Mouse VSMCs through TRAF6/NF-κB p65 Signaling Pathway
Q36404231Calycosin Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and NF-κB.
Q36356977Caveolin-1 regulates osteoclast differentiation by suppressing cFms degradation
Q52606312Cyperenoic acid suppresses osteoclast differentiation and delays bone loss in a senile osteoporosis mouse model by inhibiting non-canonical NF-κB pathway.
Q38913174DLX3 negatively regulates osteoclastic differentiation through microRNA-124.
Q50797973Development of a High-Throughput Screening Strategy for Upregulators of the OPG/RANKL Ratio with the Potential for Antiosteoporosis Effects.
Q47883783Differential intensity-dependent effects of pulsed electromagnetic fields on RANKL-induced osteoclast formation, apoptosis, and bone resorbing ability in RAW264.7 cells.
Q90609993Disulfiram suppressed ethanol promoted RANKL-induced osteoclastogenesis in vitro and ethanol-induced osteoporosis in vivo via ALDH1A1-NFATc1 axis
Q50437421Dual Role of Cyanidin-3-glucoside on the Differentiation of Bone Cells.
Q96950725Effect of echinalkamide identified from Echinacea purpurea (L.) Moench on the inhibition of osteoclastogenesis and bone resorption
Q37449518Enhanced but hypofunctional osteoclastogenesis in an autosomal dominant osteopetrosis type II case carrying a c.1856C>T mutation in CLCN7.
Q61798625Epigenetic regulation of NfatC1 transcription and osteoclastogenesis by nicotinamide phosphoribosyl transferase in the pathogenesis of arthritis
Q89805481Ethyl Acetate Fraction of Aqueous Extract of Lentinula edodes Inhibits Osteoclastogenesis by Suppressing NFATc1 Expression
Q51133979F4/80 inhibits osteoclast differentiation via downregulation of nuclear factor of activated T cells, cytoplasmic 1.
Q35819965FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans
Q92253049Felodipine blocks osteoclast differentiation and ameliorates estrogen-dependent bone loss in mice by modulating p38 signaling pathway
Q90412365Ferryl Hemoglobin Inhibits Osteoclastic Differentiation of Macrophages in Hemorrhaged Atherosclerotic Plaques
Q92527785Forsythia suspensa Protects against Bone Loss in Ovariectomized Mice
Q92662248Fucoidan Prevents RANKL-Stimulated Osteoclastogenesis and LPS-Induced Inflammatory Bone Loss via Regulation of Akt/GSK3β/PTEN/NFATc1 Signaling Pathway and Calcineurin Activity
Q47595585Gα12 regulates osteoclastogenesis by modulating NFATc1 expression
Q92059937Heshouwu (Polygonum multiflorum Thunb.) Extract Attenuates Bone Loss in Diabetic Mice
Q90290403Hexane Fraction of Turbo brunneus Inhibits Intermediates of RANK-RANKL Signaling Pathway and Prevent Ovariectomy Induced Bone Loss
Q93185779Humanin suppresses receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation via AMP-activated protein kinase activation
Q36766801Immunology of Osteoporosis: A Mini-Review
Q42374255Increased levels of sodium chloride directly increase osteoclastic differentiation and resorption in mice and men.
Q57812844Influence of Iron on Bone Homeostasis
Q92273712Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss
Q57052716Inhibition of RANKL-stimulated osteoclast differentiation by Schisandra chinensis through down-regulation of NFATc1 and c-fos expression
Q90450587Inhibitory Effect of Rosae Multiflorae Fructus Extracts on the Receptor Activator of NF-κB Ligand-Induced Osteoclastogenesis through Modulation of P38- and Ca2+-Mediated Nuclear Factor of Activated T-Cells Cytoplasmic 1 Expression
Q60928907Inhibitory Effects of 2N1HIA (2-(3-(2-Fluoro-4-Methoxyphenyl)-6-Oxo-1(6H)-Pyridazinyl)--1H-Indol-5-Ylacetamide) on Osteoclast Differentiation via Suppressing Cathepsin K Expression
Q47133316Interleukin-7 Induces Osteoclast Formation via STAT5, Independent of Receptor Activator of NF-kappaB Ligand
Q36749163Investigation of proteome changes in osteoclastogenesis in low serum culture system using quantitative proteomics.
Q64065423KBTBD11, a novel BTB-Kelch protein, is a negative regulator of osteoclastogenesis through controlling Cullin3-mediated ubiquitination of NFATc1
Q90119594Leonurus sibiricus L. ethanol extract promotes osteoblast differentiation and inhibits osteoclast formation
Q64110684Long noncoding RNAs: a missing link in osteoporosis
Q58588319Madecassoside inhibits estrogen deficiency-induced osteoporosis by suppressing RANKL-induced osteoclastogenesis
Q64900997Mannan-Binding Lectin Attenuates Inflammatory Arthritis Through the Suppression of Osteoclastogenesis.
Q58796982Meta-Analysis of Genome-Wide Association Studies Identifies Novel Functional CpG-SNPs Associated with Bone Mineral Density at Lumbar Spine
Q42068034Methylation-mediated silencing of miR-124 facilitates chondrogenesis by targeting NFATc1 under hypoxic conditions
Q64120770MicroRNAs: Key Regulators to Understand Osteoclast Differentiation?
Q89717449Multi-omics Data Integration for Identifying Osteoporosis Biomarkers and Their Biological Interaction and Causal Mechanisms
Q39142554NF-κB as a Therapeutic Target in Inflammatory-Associated Bone Diseases
Q36221462NRROS Negatively Regulates Osteoclast Differentiation by Inhibiting RANKL-Mediated NF-N:B and Reactive Oxygen Species Pathways
Q64068617Osteoclastic expression of higher-level regulators NFATc1 and BCL6 in medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis
Q37036135Osteoclasts-Key Players in Skeletal Health and Disease
Q89998406Osthole-loaded N-octyl-O-sulfonyl chitosan micelles (NSC-OST) inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in rats
Q90192899PSTP-3,5-Me Inhibits Osteoclast Differentiation and Bone Resorption
Q89996661Poncirin Inhibits Osteoclast Differentiation and Bone Loss Through Down-Regulation of NFATc1 In Vitro and In Vivo
Q38675617Potassium citrate prevents increased osteoclastogenesis resulting from acidic conditions: Implication for the treatment of postmenopausal bone loss.
Q55410884Prevention and Treatment of Osteoporosis Using Chinese Medicinal Plants: Special Emphasis on Mechanisms of Immune Modulation.
Q64994199Protocatechuic Acid Attenuates Trabecular Bone Loss in Ovariectomized Mice.
Q37472044RCANs regulate the convergent roles of NFATc1 in bone homeostasis
Q90567814Role of APD-Ribosylation in Bone Health and Disease
Q30009052Role of CrkII Signaling in RANKL-Induced Osteoclast Differentiation and Function
Q37148066STAT5 is a key transcription factor for IL-3-mediated inhibition of RANKL-induced osteoclastogenesis
Q99565104Sarsasapogenin Suppresses RANKL-Induced Osteoclastogenesis in vitro and Prevents Lipopolysaccharide-Induced Bone Loss in vivo
Q36320978Sophorae Flos extract inhibits RANKL-induced osteoclast differentiation by suppressing the NF-κB/NFATc1 pathway in mouse bone marrow cells
Q38733018TRAF6 Mediates Suppression of Osteoclastogenesis and Prevention of Ovariectomy-Induced Bone Loss by a Novel Prenylflavonoid.
Q64118002Targeted sequencing of in familial Paget's disease of bone
Q36613061The Influence of DNA Methylation on Bone Cells.
Q26778021The Multiple Roles of Microrna-223 in Regulating Bone Metabolism
Q42378776The effects of downhill and uphill exercise training on osteogenesis-related factors in ovariectomy-induced bone loss
Q33669039The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts.
Q41634435Transglutaminase 2 regulates osteoclast differentiation via a Blimp1-dependent pathway
Q64118707Turcz Inhibits the Osteoclastogenesis in RAW 264.7 Cells and Bone Loss in Ovariectomized Rat Model
Q42197175Tusc2/Fus1 regulates osteoclast differentiation through NF-κB and NFATc1.
Q92840590UHMWPE wear particles and dendritic cells promote osteoclastogenesis of RAW264.7 cells through RANK-activated NF-κB/MAPK/AKT pathways
Q90599354Umbelliferone Prevents Lipopolysaccharide-Induced Bone Loss and Suppresses RANKL-Induced Osteoclastogenesis by Attenuating Akt-c-Fos-NFATc1 Signaling
Q90294419Various roles of heme oxygenase-1 in response of bone marrow macrophages to RANKL and in the early stage of osteoclastogenesis
Q90637761Water extract of tendril of Cucurbita Moschata Duch. suppresses RANKL-induced osteoclastogenesis by down-regulating p38 and ERK signaling
Q55413820Zoledronic acid prevents disuse osteopenia and augments gene expression of osteoclastic differentiation markers in mice.
Q95522404[A review on microRNAs regulation in osteoclast differentiation and function]
Q44536102p-Coumaric acid, a dietary polyphenol ameliorates inflammation and curtails cartilage and bone erosion in the rheumatoid arthritis rat model.

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