scholarly article | Q13442814 |
P2093 | author name string | U Siebenlist | |
L Xing | |||
T Tran | |||
B F Boyce | |||
G Franzoso | |||
K D Brown | |||
A Leonardi | |||
E W Shores | |||
L Carlson | |||
L Poljak | |||
P2860 | cites work | Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk | Q24303475 |
The NF-kappa B and I kappa B proteins: new discoveries and insights | Q24313579 | ||
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei | Q27860728 | ||
The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition | Q28155838 | ||
Markers of mouse macrophage development detected by monoclonal antibodies | Q28247978 | ||
The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers | Q28260566 | ||
The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers | Q28267241 | ||
Bone acid phosphatase: tartrate-resistant acid phosphatase as a marker of osteoclast function | Q28274181 | ||
NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses | Q28505819 | ||
Immunological defects in mice with a targeted disruption in Bcl-3 | Q28506495 | ||
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB | Q28508403 | ||
Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions | Q28509551 | ||
RAG-1-deficient mice have no mature B and T lymphocytes | Q28592133 | ||
Expression of relB is required for the development of thymic medulla and dendritic cells | Q28594949 | ||
Function and activation of NF-kappa B in the immune system | Q29547790 | ||
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice | Q29547898 | ||
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB | Q29614706 | ||
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death | Q29614707 | ||
Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation | Q29615580 | ||
Germinal centers | Q29616234 | ||
Suppression of TNF-alpha-induced apoptosis by NF-kappaB | Q29618717 | ||
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death | Q29620021 | ||
Structure, regulation and function of NF-kappa B | Q29620225 | ||
Positive selection of thymocytes | Q33366862 | ||
The oncoprotein Bcl-3 can facilitate NF-kappa B-mediated transactivation by removing inhibiting p50 homodimers from select kappa B sites. | Q34061332 | ||
Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family | Q34317095 | ||
Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation | Q35361444 | ||
Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice | Q35607627 | ||
Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice | Q35824596 | ||
The Rel subunit of NF-kappaB-like transcription factors is a positive and negative regulator of macrophage gene expression: distinct roles for Rel in different macrophage populations | Q35917603 | ||
Two subsets of epithelial cells in the thymic medulla | Q36231612 | ||
Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts. | Q36301037 | ||
B cells lacking RelB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching | Q36367374 | ||
Mutant mice without B lymphocyte follicles | Q36367422 | ||
Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB. | Q36377290 | ||
Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture | Q36400143 | ||
IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice | Q36559410 | ||
Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells | Q37531252 | ||
Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor | Q37654865 | ||
Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice | Q38289217 | ||
How many women have osteoporosis now? | Q40528035 | ||
Selective events in T cell development | Q40661180 | ||
Cytokines and estrogen in bone: anti-osteoporotic effects | Q40900427 | ||
The heterogeneity of the osteopetroses reflects the diversity of cellular influences during skeletal development | Q40957485 | ||
Clonal selection and learning in the antibody system | Q41002744 | ||
Cellular interactions in thymocyte development. | Q41039662 | ||
Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells | Q41077008 | ||
Osteopetrosis in mice lacking haematopoietic transcription factor PU.1. | Q41121255 | ||
In vivo occupancy of the kappa light chain enhancers in primary pro- and pre-B cells: a model for kappa locus activation | Q41130580 | ||
A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus | Q41182422 | ||
Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op mouse | Q41205540 | ||
A conserved signaling pathway: the Drosophila toll-dorsal pathway | Q41275284 | ||
Macrophage colony-stimulating factor and interleukin-1 alpha maintain the survival of osteoclast-like cells | Q41373053 | ||
B-cell development and differentiation | Q41448847 | ||
Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation | Q41450875 | ||
The Carl Prausnitz Memorial Lecture. The development of lymphocytes | Q41454884 | ||
p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice | Q41954424 | ||
Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses | Q42488424 | ||
Thymic epithelial antibodies: immunohistological analysis and introduction of nomenclature | Q44660713 | ||
Differential nuclear localization of p50, p52, and RelB proteins in human accessory cells of the immune response in situ. | Q50335866 | ||
Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta. | Q51005281 | ||
In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. | Q52192552 | ||
Corepression of RelA and c-rel inhibits immunoglobulin kappa gene transcription and rearrangement in precursor B lymphocytes. | Q52198668 | ||
Developmental expression of the mouse c-rel proto-oncogene in hematopoietic organs | Q52214145 | ||
Regulation of 3' IgH enhancers by a common set of factors, including kappa B-binding proteins. | Q52519188 | ||
Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependent. | Q52522051 | ||
c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling | Q58326943 | ||
Bone and haematopoietic defects in mice lacking c-fos | Q58326969 | ||
Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex | Q59071991 | ||
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene | Q59092154 | ||
Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression | Q62817899 | ||
Two populations of splenic dendritic cells detected with M342, a new monoclonal to an intracellular antigen of interdigitating dendritic cells and some B lymphocytes | Q67540351 | ||
Increased osteoclast development after estrogen loss: mediation by interleukin-6 | Q68188964 | ||
Dendritic cells of the mouse recognized by two monoclonal antibodies | Q69444823 | ||
Epithelial heterogeneity in the murine thymus: fucose-specific lectins bind medullary epithelial cells | Q69834637 | ||
Deficiency of osteoclasts in osteopetrotic mice is due to a defect in the local microenvironment provided by osteoblastic cells | Q70118663 | ||
B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching | Q70994054 | ||
Role of TCR zeta chain in T cell development and selection | Q71658710 | ||
Simultaneous block of interleukin-1 and tumor necrosis factor is required to completely prevent bone loss in the early postovariectomy period | Q72332068 | ||
Expression of relB transcripts during lymphoid organ development: specific expression in dendritic antigen-presenting cells | Q72678853 | ||
Thymic cortical epithelium is sufficient for the development of mature T cells in relB-deficient mice | Q73128606 | ||
Failure of lymphopoiesis after adoptive transfer of NF-kappaB-deficient fetal liver cells | Q73479969 | ||
NF-kappaB inhibitors stimulate apoptosis of rabbit mature osteoclasts and inhibit bone resorption by these cells | Q73545409 | ||
P433 | issue | 24 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | NF-κB | Q411114 |
P304 | page(s) | 3482-3496 | |
P577 | publication date | 1997-12-01 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | Requirement for NF-kappaB in osteoclast and B-cell development | |
P478 | volume | 11 |
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Q61813305 | 20(S)-Protopanaxadiol Inhibits Titanium Particle-Induced Inflammatory Osteolysis and RANKL-Mediated Osteoclastogenesis via MAPK and NF-κB Signaling Pathways |
Q35351495 | 5-Azacytidine-induced protein 2 (AZI2) regulates bone mass by fine-tuning osteoclast survival |
Q38325962 | A 3'-flanking NF-kappaB site mediates developmental silencing of the human zeta-globin gene |
Q33754082 | A FKBP5 mutation is associated with Paget's disease of bone and enhances osteoclastogenesis. |
Q38320987 | A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation. |
Q28592979 | A dual role for Ikk alpha in tooth development |
Q34092086 | A medium-chain fatty acid, capric acid, inhibits RANKL-induced osteoclast differentiation via the suppression of NF-κB signaling and blocks cytoskeletal organization and survival in mature osteoclasts |
Q39586391 | A novel HSP90 inhibitor delays castrate-resistant prostate cancer without altering serum PSA levels and inhibits osteoclastogenesis |
Q24538937 | A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO) |
Q40684919 | A novel anti-rheumatic drug, T-614, stimulates osteoblastic differentiation in vitro and bone morphogenetic protein-2-induced bone formation in vivo |
Q37220784 | A role for nuclear factor kappa B/rel transcription factors in the regulation of the recombinase activator genes. |
Q36025311 | A role for the IkappaB family member Bcl-3 in the control of central immunologic tolerance |
Q28535889 | Acteoside suppresses RANKL-mediated osteoclastogenesis by inhibiting c-Fos induction and NF-κB pathway and attenuating ROS production |
Q34356123 | Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements |
Q41411791 | Activation of NF-kappaB by fluid shear stress, but not TNF-alpha, requires focal adhesion kinase in osteoblasts |
Q40920365 | Activation of NF-kappaB in human osteoblasts by stimulators of bone resorption |
Q37318889 | Activation of adenosine A(2A) receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation |
Q40103919 | Activation of transcription factors by extracellular nucleotides in immune and related cell types. |
Q35953968 | Adenosine A1 receptor regulates osteoclast formation by altering TRAF6/TAK1 signaling. |
Q33919462 | Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function. |
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Q89848783 | Amaranthus mangostanus Inhibits the Differentiation of Osteoclasts and Prevents Ovariectomy-Induced Bone Loss |
Q42474614 | An intact NF-kappa B signaling pathway is required for maintenance of mature B cell subsets |
Q42143881 | An overview of bone cells and their regulating factors of differentiation. |
Q36324729 | Andrographolide Inhibits Ovariectomy-Induced Bone Loss via the Suppression of RANKL Signaling Pathways. |
Q39028702 | Andrographolide prevents human breast cancer-induced osteoclastic bone loss via attenuated RANKL signaling. |
Q34547252 | Antigen-dependent B-cell development |
Q35007314 | Aryl hydrocarbon receptors in osteoclast lineage cells are a negative regulator of bone mass |
Q35629551 | Aseptic loosening |
Q36496869 | Aseptic loosening, not only a question of wear: a review of different theories |
Q38005624 | Association of MicroRNA-146a with autoimmune diseases. |
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Q37496714 | Attenuation of RANKL-induced Osteoclast Formation via p38-mediated NFATc1 Signaling Pathways by Extract of Euphorbia Lathyris L. |
Q34296482 | Attractions and migrations of lymphoid cells in the organization of humoral immune responses |
Q35062895 | Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100. |
Q90191173 | Avian Reticuloendotheliosis Viral Oncogene Related B Regulates Lymphatic Endothelial Cells during Vessel Maturation and Is Required for Lymphatic Vessel Function in Adult Mice |
Q34314392 | B-1a transitional cells are phenotypically distinct and are lacking in mice deficient in IκBNS. |
Q36675058 | B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel. |
Q53664665 | BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells. |
Q34366449 | Biology of the RANKL-RANK-OPG System in Immunity, Bone, and Beyond |
Q35145622 | Biology of the TRANCE axis |
Q61796335 | Bone Metastasis Pain, from the Bench to the Bedside |
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Q24805142 | Bone loss. Factors that regulate osteoclast differentiation: an update |
Q42919718 | Bone sialoprotein deficiency impairs osteoclastogenesis and mineral resorption in vitro |
Q46265917 | Bone-protective Functions of Netrin 1 Protein. |
Q40733095 | Both N- and C-terminal domains of parathyroid hormone-related protein increase interleukin-6 by nuclear factor-kappa B activation in osteoblastic cells. |
Q52605959 | CHIP regulates bone mass by targeting multiple TRAF family members in bone marrow stromal cells. |
Q39812715 | Caffeic acid phenethyl ester, an active component of honeybee propolis attenuates osteoclastogenesis and bone resorption via the suppression of RANKL-induced NF-kappaB and NFAT activity. |
Q43624124 | Carbonic anhydrase II is an AP-1 target gene in osteoclasts |
Q33831453 | Carboxyl terminus of Hsp70-interacting protein regulation of osteoclast formation in mice through promotion of tumor necrosis factor receptor-associated factor 6 protein degradation |
Q35173015 | Caveolin-1 regulates osteoclastogenesis and bone metabolism in a sex-dependent manner |
Q37120661 | Cell-autonomous role for NF-kappa B in immature bone marrow B cells |
Q34793358 | Cellular, molecular, and genetic determinants of tooth eruption |
Q35709514 | Cherubism gene Sh3bp2 is important for optimal bone formation, osteoblast differentiation, and function |
Q37410560 | Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation |
Q35951712 | Combination gene therapy targeting on interleukin-1β and RANKL for wear debris-induced aseptic loosening. |
Q54384101 | Combination of tumor necrosis factor α and interleukin-6 induces mouse osteoclast-like cells with bone resorption activity both in vitro and in vivo. |
Q36375584 | Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors |
Q33678395 | Commitment and differentiation of stem cells to the osteoclast lineage |
Q89878373 | Comparative Transcriptomics Analysis of Testicular miRNA from Cryptorchid and Normal Horses |
Q38875853 | Compressive mechanical stress may activate IKK-NF-κB through proinflammatory cytokines in MC3T3-E1 cells |
Q35084291 | Concerted action of the chemokine and lymphotoxin system in secondary lymphoid-organ development |
Q38835068 | Conditional deletion of epithelial IKKβ impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis |
Q53664694 | Constitutive nuclear factor-kappa B activity is required for central neuron survival. |
Q34299726 | Constitutively active canonical NF-κB pathway induces severe bone loss in mice |
Q73588967 | Contribution of BCAP to maintenance of mature B cells through c-Rel |
Q37038278 | Contributions to osteoclast biology from Japan |
Q37608919 | Control of bone development by P2X and P2Y receptors expressed in mesenchymal and hematopoietic cells |
Q36133144 | Control of lymphocyte development by nuclear factor-kappaB. |
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Q38357169 | CpG oligodeoxynucleotides modulate the osteoclastogenic activity of osteoblasts via Toll-like receptor 9. |
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Q47131626 | Current Understanding of RANK Signaling in Osteoclast Differentiation and Maturation |
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Q36350166 | Cytoplasmic hnRNPK interacts with GSK3β and is essential for the osteoclast differentiation |
Q39328894 | D-chiro-inositol negatively regulates the formation of multinucleated osteoclasts by down-regulating NFATc1. |
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Q37333361 | Dento-craniofacial phenotypes and underlying molecular mechanisms in hypohidrotic ectodermal dysplasia (HED): a review. |
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Q36404338 | Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP) |
Q37855820 | Direct Rel/NF-κB inhibitors: structural basis for mechanism of action |
Q52633378 | Disruption of NF-κB1 prevents bone loss caused by mechanical unloading. |
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Q28546890 | Disulfiram attenuates osteoclast differentiation in vitro: a potential antiresorptive agent |
Q90609993 | Disulfiram suppressed ethanol promoted RANKL-induced osteoclastogenesis in vitro and ethanol-induced osteoporosis in vivo via ALDH1A1-NFATc1 axis |
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Q48014316 | Downstream activation of a TATA-less promoter by Oct-2, Bob1, and NF-kappaB directs expression of the homing receptor BLR1 to mature B cells. |
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Q36390005 | E proteins regulate osteoclast maturation and survival |
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Q42182512 | Embelin sensitizes acute myeloid leukemia cells to TRAIL through XIAP inhibition and NF-κB inactivation |
Q34279869 | Embelin suppresses osteoclastogenesis induced by receptor activator of NF-κB ligand and tumor cells in vitro through inhibition of the NF-κB cell signaling pathway |
Q39315400 | Epidermal Langerhans cells promote skin allograft rejection in mice with NF-kappa B-impaired T cells |
Q40610387 | Erythromycin inhibits wear debris-induced osteoclastogenesis by modulation of murine macrophage NF-kappaB activity |
Q38315475 | Essential role of human leukocyte antigen-encoded proteasome subunits in NF-kappaB activation and prevention of tumor necrosis factor-alpha-induced apoptosis |
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Q35169193 | Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression |
Q51695975 | Expression characteristic and significance of interleukin-6, nuclear factor kappa beta, and bone formation markers in rat models of osteoporosis. |
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Q57533748 | Expression of functional RANK on mature rat and human osteoclasts |
Q37203211 | Expression, signaling, and function of P2X7 receptors in bone. |
Q92591252 | Fangchinoline protects against bone loss in OVX mice via inhibiting osteoclast formation, bone resorption and RANKL-induced signaling |
Q35566321 | Formation of B-1 B cells from neonatal B-1 transitional cells exhibits NF-κB redundancy. |
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Q37730952 | Functions of nuclear factor kappaB in bone |
Q38748844 | G protein-coupled receptor 84 controls osteoclastogenesis through inhibition of NF-κB and MAPK signaling pathways. |
Q55714899 | GAG and collagen II attenuate glucocorticoid-induced osteoporosis by regulating NF-κB and MAPK signaling. |
Q38787481 | Gene expression in the Gitr locus is regulated by NF-κB and Foxp3 through an enhancer |
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Q38113210 | Immunology and bone |
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Q35558806 | Infections in Patients with Inherited Defects in Phagocytic Function |
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Q48006799 | Involvement of upstream stimulatory factors 1 and 2 in RANKL-induced transcription of tartrate-resistant acid phosphatase gene during osteoclast differentiation |
Q37995679 | It takes two to tango: IκBs, the multifunctional partners of NF-κB. |
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Q52005562 | Mature T cells depend on signaling through the IKK complex. |
Q37106639 | Mechanisms modulating inflammatory osteolysis: a review with insights into therapeutic targets |
Q26992028 | Mechanisms of bone anabolism regulated by statins |
Q37146973 | Mechanisms of tooth eruption and orthodontic tooth movement |
Q36073894 | Mechanistic insight into osteoclast differentiation in osteoimmunology |
Q27023608 | Mesenchymal progenitors and the osteoblast lineage in bone marrow hematopoietic niches |
Q28551882 | Metformin Improves Diabetic Bone Health by Re-Balancing Catabolism and Nitrogen Disposal |
Q34246045 | Mice Deficient in NF-κB p50 and p52 or RANK Have Defective Growth Plate Formation and Post-natal Dwarfism. |
Q26830890 | MicroRNA-146a: A Dominant, Negative Regulator of the Innate Immune Response |
Q38753732 | MicroRNA-3178 ameliorates inflammation and gastric carcinogenesis promoted by Helicobacter pylori new toxin, Tip-α, by targeting TRAF3. |
Q37971335 | MicroRNAs and their roles in osteoclast differentiation |
Q33848784 | Mitf induction by RANKL is critical for osteoclastogenesis |
Q39592784 | Molecular and functional characteristics of heart-valve interstitial cells |
Q34106530 | Molecular control of bone remodeling and osteoporosis |
Q38074961 | Molecular mechanisms of triggering, amplifying and targeting RANK signaling in osteoclasts |
Q33944879 | Mouse genetics have uncovered new paradigms in bone biology |
Q33597403 | Multiple signals converging on NF-kappaB. |
Q37085639 | Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2 |
Q35953074 | Mutation in Osteoactivin Promotes Receptor Activator of NFκB Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast Function |
Q37111047 | Myeloid Deletion of Nemo Causes Osteopetrosis in Mice Owing to Upregulation of Transcriptional Repressors |
Q30278787 | Myeloid-derived suppressor cells contribute to bone erosion in collagen-induced arthritis by differentiating to osteoclasts |
Q36238400 | Myocardial NF-κB activation is essential for zebrafish heart regeneration. |
Q62806043 | NEMO/IKK gamma: linking NF-kappa B to human disease. |
Q33840418 | NF-(kappa)B-inducing kinase controls lymphocyte and osteoclast activities in inflammatory arthritis |
Q46831922 | NF-kB induces lung maturation during mouse lung morphogenesis |
Q24803655 | NF-kB inhibitor blocks B cell development at two checkpoints |
Q73291757 | NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development |
Q28271031 | NF-kappaB and the immune response |
Q33840493 | NF-kappaB and the innate immune response |
Q33959017 | NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. |
Q34720640 | NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions. |
Q36401969 | NF-kappaB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor |
Q37363042 | NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism |
Q37231783 | NF-kappaB pathways in the immune system: control of the germinal center reaction |
Q28205043 | NF-kappaB regulation in the immune system |
Q34264609 | NF-kappaB signaling and human disease |
Q34013841 | NF-kappaB transcription factors: critical regulators of hematopoiesis and neuronal survival |
Q28290224 | NF-kappaB-related genetic diseases |
Q33930920 | NF-kappaB/rel/IkappaB: implications in gastrointestinal diseases |
Q42009786 | NF-kappaB2 (p100) limits TNF-alpha-induced osteoclastogenesis |
Q35740901 | NF-kappaB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells |
Q29617726 | NF-kappaB: a key role in inflammatory diseases |
Q37653034 | NF-κB RelB negatively regulates osteoblast differentiation and bone formation |
Q92012828 | NF-κB Signaling Regulates Physiological and Pathological Chondrogenesis |
Q104795129 | NF-κB activity during pancreas development regulates adult β-cell mass by modulating neonatal β-cell proliferation and apoptosis |
Q39142554 | NF-κB as a Therapeutic Target in Inflammatory-Associated Bone Diseases |
Q35348282 | NF-κB in immunobiology. |
Q57675122 | NF-κB p50 and p52 Regulate Receptor Activator of NF-κB Ligand (RANKL) and Tumor Necrosis Factor-induced Osteoclast Precursor Differentiation by Activating c-Fos and NFATc1 |
Q38178074 | NF-κB pathways in hematological malignancies |
Q37449635 | NF-κB signaling and bone resorption |
Q38533864 | NF-κB signaling in B-1 cell development |
Q38025541 | NF-κB signaling pathways: role in nervous system physiology and pathology |
Q35260971 | NF-κB-Mediated Regulation of Osteoclastogenesis |
Q33768994 | NIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysis |
Q40632338 | NMDA glutamate receptors are expressed by osteoclast precursors and involved in the regulation of osteoclastogenesis |
Q33961022 | NOD mice are defective in proteasome production and activation of NF-kappaB |
Q33808220 | NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB. |
Q39491637 | Naringin abrogates osteoclastogenesis and bone resorption via the inhibition of RANKL-induced NF-κB and ERK activation |
Q36324551 | Natural Germacrane Sesquiterpenes Inhibit Osteoclast Formation, Bone Resorption, RANKL-Induced NF-κB Activation, and IκBα Degradation. |
Q23923136 | New insights into the role of nuclear factor-KB, a ubiquitous transcription factor in the initiation of diseases |
Q33785173 | New insights into the roles of ReL/NF-kappa B transcription factors in immune function, hemopoiesis and human disease |
Q37987556 | New regulation mechanisms of osteoclast differentiation |
Q49793888 | Niche signals and transcription factors involved in tissue-resident macrophage development |
Q52317346 | Niches for Hematopoietic Stem Cells and Their Progeny. |
Q27024640 | Non-Canonical NF-κB Signaling Initiated by BAFF Influences B Cell Biology at Multiple Junctures |
Q36635311 | Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation. |
Q34530518 | Noncanonical G-protein-dependent modulation of osteoclast differentiation and bone resorption mediated by Pasteurella multocida toxin |
Q43224836 | Noncanonical NF-κB signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions. |
Q38305549 | Novel NF-κB inhibitors: a patent review (2011 - 2014). |
Q34806538 | Novel functions for NFκB: inhibition of bone formation |
Q36830310 | Novel osteoclast signaling mechanisms. |
Q35107411 | Nuclear factor-kappaB (NF-kappaB) p65 interacts with Stat5b in growth plate chondrocytes and mediates the effects of growth hormone on chondrogenesis and on the expression of insulin-like growth factor-1 and bone morphogenetic protein-2 |
Q36283770 | Nuclear factor-kappaB (NF-kappaB) regulates proliferation and branching in mouse mammary epithelium |
Q28566184 | Nuclear factor-kappaB p65 facilitates longitudinal bone growth by inducing growth plate chondrocyte proliferation and differentiation and by preventing apoptosis |
Q35791198 | Nuclear factor-kappaB: its role in health and disease |
Q35008666 | Nuclear transcription factors in the hippocampus. |
Q28817299 | OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo |
Q28589430 | OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis |
Q35787723 | Onset and dynamics of osteosclerosis in mice induced by Reilly-Finkel-Biskis (RFB) murine leukemia virus. Increase in bone mass precedes lymphomagenesis |
Q36040583 | Osteoblast-induced osteoclast apoptosis by fas ligand/FAS pathway is required for maintenance of bone mass |
Q35348955 | Osteoclast activity modulates B-cell development in the bone marrow |
Q29547556 | Osteoclast differentiation and activation |
Q28593804 | Osteoclast differentiation is impaired in the absence of inhibitor of kappa B kinase alpha |
Q36568536 | Osteoclast fusion and regulation by RANKL-dependent and independent factors |
Q37489600 | Osteoclasts and the immune system |
Q24683898 | Osteoclasts: what do they do and how do they do it? |
Q34896003 | Osteoclasts; culprits in inflammatory osteolysis |
Q36514172 | Osteocyte control of osteoclastogenesis |
Q88248494 | Osteoimmunology |
Q47944184 | Osteoimmunology: The Conceptual Framework Unifying the Immune and Skeletal Systems. |
Q36942525 | Osteoimmunology: a view from the bone |
Q37544448 | Osteoimmunology: crosstalk between the immune and bone systems |
Q38960189 | Osteoimmunology: memorandum for rheumatologists. |
Q28294477 | Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems |
Q54588690 | Osteopontin is associated with nuclear factor kappaB gene expression during tail-suspension-induced bone loss. |
Q41753607 | Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo |
Q33611312 | Osteoprotegerin ligand: a common link between osteoclastogenesis, lymph node formation and lymphocyte development. |
Q54586775 | Overexpression of Bcl-3 inhibits the development of marginal zone B cells. |
Q33916614 | Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis. |
Q40966176 | Overexpression of RelA causes G1 arrest and apoptosis in a pro-B cell line |
Q45275681 | P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts |
Q38744013 | PLCgamma2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2. |
Q58699564 | PRMT1 mediates RANKL-induced osteoclastogenesis and contributes to bone loss in ovariectomized mice |
Q40686068 | PTEN regulates RANKL- and osteopontin-stimulated signal transduction during osteoclast differentiation and cell motility |
Q40773247 | PU.1/Spi-B regulation of c-rel is essential for mature B cell survival |
Q36029217 | Paget disease of bone |
Q42197999 | Parthenolide inhibits osteoclast differentiation and bone resorbing activity by down-regulation of NFATc1 induction and c-Fos stability, during RANKL-mediated osteoclastogenesis |
Q92798193 | Pentamidine Inhibits Titanium Particle-Induced Osteolysis In Vivo and Receptor Activator of Nuclear Factor-κB Ligand-Mediated Osteoclast Differentiation In Vitro |
Q36944827 | Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis |
Q91941325 | Piceatannol attenuates RANKL-induced osteoclast differentiation and bone resorption by suppressing MAPK, NF-κB and AKT signalling pathways and promotes Caspase3-mediated apoptosis of mature osteoclasts |
Q51395263 | Platycodin D Inhibits Osteoclastogenesis by Repressing the NFATc1 and MAPK Signaling Pathway. |
Q35751362 | Plumbagin inhibits osteoclastogenesis and reduces human breast cancer-induced osteolytic bone metastasis in mice through suppression of RANKL signaling |
Q35617594 | Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis |
Q41008741 | Possible stage-specific function of NF-kappaB during pre-B cell differentiation |
Q40596266 | Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas |
Q35085082 | Proepithelin stimulates growth plate chondrogenesis via nuclear factor-kappaB-p65-dependent mechanisms |
Q73150091 | Progressive increase in bone mass and development of odontomas in aging osteopetrotic c-src-deficient mice |
Q33391408 | Protective protein/cathepsin A down-regulates osteoclastogenesis by associating with and degrading NF-kappaB p50/p65. |
Q38943284 | Protein kinase C inhibitor, GF109203X attenuates osteoclastogenesis, bone resorption and RANKL-induced NF-κB and NFAT activity. |
Q92099986 | Protocatechuic acid attenuates anterior cruciate ligament transection-induced osteoarthritis by suppressing osteoclastogenesis |
Q38691526 | RANK as a therapeutic target in cancer. |
Q24598872 | RANK is essential for osteoclast and lymph node development |
Q37108966 | RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism |
Q41107411 | RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis. |
Q40326890 | RANKing the importance of measles virus in Paget's disease |
Q24629421 | RGS12 is essential for RANKL-evoked signaling for terminal differentiation of osteoclasts in vitro |
Q58776864 | Rab GTPases in Osteoclastic Endomembrane Systems |
Q34611297 | Reaching a genetic and molecular understanding of skeletal development |
Q50215136 | Recent advances in osteoclast biology. |
Q40633180 | Receptor Activator of NF-κB Ligand Stimulates Recruitment of SHP-1 to the Complex Containing TNFR-Associated Factor 6 That Regulates Osteoclastogenesis |
Q42918767 | Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts |
Q43855536 | Regulating DeltaFosB expression in adult Tet-Off-DeltaFosB transgenic mice alters bone formation and bone mass |
Q35014068 | Regulation of B-cell fate by antigen-receptor signals |
Q38324140 | Regulation of NF-kappaB activity by I kappaB-related proteins in adenocarcinoma cells |
Q27021109 | Regulation of NFATc1 in Osteoclast Differentiation |
Q24657260 | Regulation of hypoxia-inducible factor-1alpha by NF-kappaB |
Q38774316 | Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit |
Q40796459 | Regulation of receptor activator of NF-kappaB ligand-induced tartrate-resistant acid phosphatase gene expression by PU.1-interacting protein/interferon regulatory factor-4. Synergism with microphthalmia transcription factor |
Q35216951 | Regulation of secondary lymphoid organ development by the nuclear factor-kappaB signal transduction pathway |
Q38132390 | Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases |
Q34728971 | Regulatory mechanisms of osteoblast and osteoclast differentiation |
Q36638965 | RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice |
Q36499078 | RelB is the NF-kappaB subunit downstream of NIK responsible for osteoclast differentiation |
Q35292814 | RelB nuclear translocation regulates B cell MHC molecule, CD40 expression, and antigen-presenting cell function. |
Q37635761 | RelB-induced expression of Cot, an MAP3K family member, rescues RANKL-induced osteoclastogenesis in alymphoplasia mice by promoting NF-κB2 processing by IKKα. |
Q78049289 | Required and nonessential functions of nuclear factor-kappa B in bone cells |
Q35174052 | Requirement of the inducible nitric oxide synthase pathway for IL-1-induced osteoclastic bone resorption |
Q39607279 | Resveratrol-mediated SIRT-1 interactions with p300 modulate receptor activator of NF-kappaB ligand (RANKL) activation of NF-kappaB signaling and inhibit osteoclastogenesis in bone-derived cells |
Q34078699 | Retracted: Intermittent Hypoxia Effect on Osteoclastogenesis Stimulated by Neuroblastoma Cells |
Q73226560 | Role of B lymphocytes in new bone formation |
Q39221657 | Role of FK506 binding protein 5 (FKBP5) in osteoclast differentiation |
Q35347883 | Role of NF-κB in the skeleton |
Q34963016 | Role of RANKL and RANK in bone loss and arthritis. |
Q37118770 | Role of the NF-kappaB axis in immune modulation of osteoclasts and bone loss |
Q36177501 | Roles for NF-kappaB and c-Fos in osteoclasts |
Q33800318 | Roles of the NF-kappaB pathway in lymphocyte development and function |
Q39817003 | Saurolactam inhibits osteoclast differentiation and stimulates apoptosis of mature osteoclasts |
Q39714931 | Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis |
Q47446256 | Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo |
Q33752186 | Selectivity of the NF-{kappa}B response |
Q34116362 | Series introduction: the transcription factor NF-kappaB and human disease |
Q26766637 | Signaling Pathways in Osteoclast Differentiation |
Q36082866 | Signaling networks that control the lineage commitment and differentiation of bone cells |
Q35553533 | Signalling in osteoclasts and the role of Fos/AP1 proteins |
Q34582666 | Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program |
Q39020213 | Small non-coding RNAs-based bone regulation and targeting therapeutic strategies. |
Q36320978 | Sophorae Flos extract inhibits RANKL-induced osteoclast differentiation by suppressing the NF-κB/NFATc1 pathway in mouse bone marrow cells |
Q33299652 | Specificity of RGS10A as a key component in the RANKL signaling mechanism for osteoclast differentiation |
Q34182834 | Src inhibitors in the treatment of metastatic bone disease: rationale and clinical data |
Q24301850 | Stimulation by toll-like receptors inhibits osteoclast differentiation |
Q39957832 | Stimulation of macrophage TNFalpha production by orthopaedic wear particles requires activation of the ERK1/2/Egr-1 and NF-kappaB pathways but is independent of p38 and JNK. |
Q41954511 | Stimulatory effects of insulin-like growth factor-I on growth plate chondrogenesis are mediated by nuclear factor-kappaB p65 |
Q28586492 | Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP |
Q34166675 | Strength of TRAF6 signalling determines osteoclastogenesis |
Q58079146 | Substance P upregulates osteoclastogenesis by activating nuclear factor kappa B in osteoclast precursors |
Q91711303 | Substrate complex competition is a regulatory motif that allows NFκB RelA to license but not amplify NFκB RelB |
Q38972321 | Suppression of NF-κB activation by gentian violet promotes osteoblastogenesis and suppresses osteoclastogenesis |
Q36185717 | Synergistic Effect of Sorafenib and Radiation on Human Oral Carcinoma in vivo. |
Q43641805 | TAT fusion proteins containing tyrosine 42-deleted IkappaBalpha arrest osteoclastogenesis |
Q35750113 | TNF Induction of NF-κB RelB Enhances RANKL-Induced Osteoclastogenesis by Promoting Inflammatory Macrophage Differentiation but also Limits It through Suppression of NFATc1 Expression |
Q38042619 | TNF receptor family signaling in the development and functions of medullary thymic epithelial cells |
Q34471711 | TRAF family member-associated NF-κB activator (TANK) induced by RANKL negatively regulates osteoclasts survival and function |
Q36217430 | TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation |
Q24300996 | TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor |
Q38733018 | TRAF6 Mediates Suppression of Osteoclastogenesis and Prevention of Ovariectomy-Induced Bone Loss by a Novel Prenylflavonoid. |
Q28513445 | TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling |
Q46592953 | Thapsigargin modulates osteoclastogenesis through the regulation of RANKL-induced signaling pathways and reactive oxygen species production. |
Q41684447 | The Beneficial Effect of Praeruptorin C on Osteoporotic Bone in Ovariectomized Mice via Suppression of Osteoclast Formation and Bone Resorption |
Q41062466 | The HIV protease inhibitor ritonavir blocks osteoclastogenesis and function by impairing RANKL-induced signaling |
Q36371653 | The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis |
Q28512132 | The LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast development |
Q41161836 | The Nuclear Protein IκBζ Forms a Transcriptionally Active Complex with Nuclear Factor-κB (NF-κB) p50 and the Lcn2 Promoter via the N- and C-terminal Ankyrin Repeat Motifs |
Q92050583 | The Role of NF-κB in Physiological Bone Development and Inflammatory Bone Diseases: Is NF-κB Inhibition "Killing Two Birds with One Stone"? |
Q33187279 | The TNF family members BAFF and APRIL: the growing complexity |
Q34682769 | The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression |
Q28508398 | The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis |
Q51040187 | The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis. |
Q38940135 | The botanical molecule p-hydroxycinnamic acid as a new osteogenic agent: insight into the treatment of cancer bone metastases |
Q36796472 | The central role of wear debris in periprosthetic osteolysis |
Q33657947 | The chosen few? Positive selection and the generation of naive B lymphocytes |
Q34048761 | The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells |
Q35716042 | The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects |
Q35128219 | The complexities of skeletal biology |
Q37700164 | The complicated role of NF-kappaB in T-cell selection. |
Q38669228 | The effects of tumour necrosis factor-α on bone cells involved in periodontal alveolar bone loss; osteoclasts, osteoblasts and osteocytes. |
Q28274046 | The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor |
Q30481368 | The glycosaminoglycan-binding domain of PRELP acts as a cell type-specific NF-kappaB inhibitor that impairs osteoclastogenesis |
Q35216957 | The impact of CCR7 and CXCR5 on lymphoid organ development and systemic immunity |
Q28577304 | The intracellular domain of CD44 promotes the fusion of macrophages |
Q38654344 | The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state |
Q42905527 | The paired-box homeodomain transcription factor Pax6 binds to the upstream region of the TRAP gene promoter and suppresses receptor activator of NF-κB ligand (RANKL)-induced osteoclast differentiation. |
Q34827459 | The polyphenol fisetin protects bone by repressing NF-κB and MKP-1-dependent signaling pathways in osteoclasts |
Q52532301 | The protein tyrosine kinase p60c-Src is not implicated in the pathogenesis of the human autosomal recessive form of osteopetrosis: a study of 13 children. |
Q47933661 | The regulation and roles of Rel/NF-kappa B transcription factors during lymphocyte activation |
Q35561576 | The role of Rel/NF-kappaB transcription factors in B lymphocyte survival |
Q24805207 | The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption. |
Q36731651 | The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms. |
Q44681011 | The tyrosine kinase inhibitor GNF-2 suppresses osteoclast formation and activity |
Q38997808 | Therapeutic Effect of Cistanoside A on Bone Metabolism of Ovariectomized Mice |
Q36147288 | Thiocolchicoside suppresses osteoclastogenesis induced by RANKL and cancer cells through inhibition of inflammatory pathways: a new use for an old drug. |
Q37696067 | Transcriptional control of the TNF gene |
Q36146925 | Transcriptional networks in developing and mature B cells |
Q38290706 | Transcriptional program of mouse osteoclast differentiation governed by the macrophage colony-stimulating factor and the ligand for the receptor activator of NFkappa B. |
Q46346390 | Transcriptional regulation of B-cell differentiation |
Q39340507 | Transcriptomics, NF-κB Pathway, and Their Potential Spaceflight-Related Health Consequences |
Q41004339 | Transforming growth factor-beta stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells |
Q35155960 | Transitional B cells: step by step towards immune competence |
Q38260633 | Translational biology of osteosarcoma |
Q37185295 | Trolox prevents osteoclastogenesis by suppressing RANKL expression and signaling |
Q24653311 | Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand |
Q73853199 | Tumor necrosis factor-alpha cooperates with receptor activator of nuclear factor kappaB ligand in generation of osteoclasts in stromal cell-depleted rat bone marrow cell culture |
Q35592741 | Tumor necrosis factor-alpha: molecular and cellular mechanisms in skeletal pathology |
Q42197175 | Tusc2/Fus1 regulates osteoclast differentiation through NF-κB and NFATc1. |
Q42139802 | Ubiquitin E3 Ligase LNX2 is Critical for Osteoclastogenesis In Vitro by Regulating M-CSF/RANKL Signaling and Notch2. |
Q36838785 | Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins |
Q36637897 | Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models. |
Q35877574 | When developmental biology meets human pathology |
Q28204249 | X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling |
Q36413357 | ZIP4 silencing improves bone loss in pancreatic cancer |
Q51842272 | Zerumbone abolishes RANKL-induced NF-kappaB activation, inhibits osteoclastogenesis, and suppresses human breast cancer-induced bone loss in athymic nude mice. |
Q40591694 | p38 MAPK-induced nuclear factor-kappaB activity is required for skeletal muscle differentiation: role of interleukin-6. |
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