Osteoimmunology: a view from the bone

scientific article published on January 2007

Osteoimmunology: a view from the bone is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S0065-2776(07)95005-1
P698PubMed publication ID17869613

P2093author name stringJean-Pierre David
P2860cites workCommitment to the B-lymphoid lineage depends on the transcription factor Pax5Q22010683
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
Mutation of the mouse klotho gene leads to a syndrome resembling ageingQ24328782
IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKLQ24338171
Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritisQ24564656
RANK is essential for osteoclast and lymph node developmentQ24598872
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationQ24603266
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient miceQ28140546
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-SrcQ28142620
The TNF and TNF receptor superfamilies: integrating mammalian biologyQ28203717
Interferons, immunity and cancer immunoeditingQ28270336
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiencyQ28284581
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signalingQ28513445
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Osteoblastic cells regulate the haematopoietic stem cell nicheQ29615007
Identification of the haematopoietic stem cell niche and control of the niche sizeQ29615008
Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic miceQ47776871
TRAF2 is essential for TNF-alpha-induced osteoclastogenesis.Q50335956
Connection between B lymphocyte and osteoclast differentiation pathways.Q52130852
Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.Q52192178
Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors.Q54784059
Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cellsQ57184743
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-βQ57675150
Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1Q57675161
Interleukin-4 Reversibly Inhibits Osteoclastogenesis via Inhibition of NF-κB and Mitogen-activated Protein Kinase SignalingQ58085461
JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanismsQ58326878
Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAPQ58326934
c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodelingQ58326943
Bone and haematopoietic defects in mice lacking c-fosQ58326969
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γQ59064307
Therapeutic targeting of a stem cell nicheQ61802299
Pleiotropic effects of a null mutation in the c-fos proto-oncogeneQ62555352
Interferon-gamma directly inhibits TRANCE-induced osteoclastogenesisQ73067239
Activated T lymphocytes support osteoclast formation in vitroQ73149439
Regulation of receptor activator of NF-kappa B ligand-induced osteoclastogenesis by endogenous interferon-beta (INF-beta ) and suppressors of cytokine signaling (SOCS). The possible counteracting role of SOCSs- in IFN-beta-inhibited osteoclast formaQ74148039
Tumor necrosis factor alpha-induced osteoclastogenesis requires tumor necrosis factor receptor-associated factor 6Q74488822
Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: effects on synovial inflammation, bone erosion, and cartilage destructionQ75288496
Dickkopf-1 is a master regulator of joint remodelingQ79610564
Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cellsQ81676385
Signalling pathways of the TNF superfamily: a double-edged swordQ29616428
Genetic regulation of osteoclast development and functionQ29617421
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclastsQ29618116
Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopeniaQ33853506
Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interactionQ33886695
Stepwise reprogramming of B cells into macrophagesQ33978638
Hematopoiesis is severely altered in mice with an induced osteoblast deficiencyQ34290169
Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteinsQ34451039
Reaching a genetic and molecular understanding of skeletal developmentQ34611297
Osteoclasts are essential for TNF-alpha-mediated joint destructionQ34826003
Mechanisms of TNF-alpha- and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritisQ34967810
Requirement for NF-kappaB in osteoclast and B-cell developmentQ35199657
IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activationQ35219971
Inflammatory Mediators as Essential Elements in Bone RemodelingQ35562458
Bone loss in inflammatory arthritis: mechanisms and treatment strategiesQ35808004
Novel aspects of osteoclast activation and osteoblast inhibition in myeloma bone diseaseQ36282334
Matrix metalloproteinase 9 and vascular endothelial growth factor are essential for osteoclast recruitment into developing long bonesQ36316526
B cells and osteoblast and osteoclast developmentQ36324944
Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responsesQ36400158
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool sizeQ36403763
Determinants of lymphoid-myeloid lineage diversificationQ36427387
Stromal niches, plasma cell differentiation and survival.Q36450001
The stem cell niches in boneQ36467113
Cytokines regulating osteoclast formation and functionQ36501069
Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition.Q36569101
Dissociation between bone resorption and bone formation in osteopenic transgenic miceQ36800774
TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligandQ37413745
Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPalpha and GATA factorsQ39804736
IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-kappaBQ39946703
Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cellsQ40277201
Regulation of cancer cell migration and bone metastasis by RANKL.Q40298349
Pax5-deficient mice exhibit early onset osteopenia with increased osteoclast progenitorsQ40489394
TRAF5 functions in both RANKL- and TNFalpha-induced osteoclastogenesisQ40666297
G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.Q40724468
Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell functionQ40736018
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destructionQ41927546
Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responsesQ42488424
Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathwaysQ42494588
Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environmentQ43181439
Bifurcation of osteoclasts and dendritic cells from common progenitorsQ43757343
Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerinQ43937881
P304page(s)149-165
P577publication date2007-01-01
P1433published inAdvances in ImmunologyQ15752932
P1476titleOsteoimmunology: a view from the bone
P478volume95

Reverse relations

cites work (P2860)
Q36838568Dendritic cell-mediated in vivo bone resorption.
Q48530248Factors associated with low bone density among women with major depressive disorder
Q37829690Interaction between the skeletal and immune systems in cancer: mechanisms and clinical implications
Q39318199Interferon-β-induced miR-155 inhibits osteoclast differentiation by targeting SOCS1 and MITF.
Q41985907Modulation of inflammasome-mediated pulmonary immune activation by type I IFNs protects bone marrow homeostasis during systemic responses to Pneumocystis lung infection
Q34305347Osteoclast activated FoxP3+ CD8+ T-cells suppress bone resorption in vitro.
Q36949734Osteoclasts and CD8 T cells form a negative feedback loop that contributes to homeostasis of both the skeletal and immune systems
Q28301682Recent advances in the renal-skeletal-gut axis that controls phosphate homeostasis
Q35085107TLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NF-kappaB.
Q55717414The P2X7 receptor: a key player in immune-mediated bone loss?
Q91899943The Role of Immune Regulatory Cells in Nontraumatic Osteonecrosis of the Femoral Head: A Retrospective Clinical Study
Q37806610The multiple faces of autoimmune-mediated bone loss

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