Osteoimmunology: memorandum for rheumatologists.

scientific article published on 20 September 2016

Osteoimmunology: memorandum for rheumatologists. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1010086354
P356DOI10.1007/S11427-016-5105-7
P698PubMed publication ID27650950

P50authorXuan ZhangQ56374184
P2093author name stringLidan Zhao
Linfang Huang
P2860cites workEmerging Functions of RANKL in Lymphoid TissuesQ21131222
Commitment to the B-lymphoid lineage depends on the transcription factor Pax5Q22010683
Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutationsQ24310432
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cellsQ24315251
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
RANK is essential for osteoclast and lymph node developmentQ24598872
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationQ24603266
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKLQ24799036
Osteoimmunology: the study of the relationship between the immune system and bone tissueQ26996266
Denosumab: a novel antiresorptive drug for osteoporosisQ28082084
Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritisQ28118730
Bone versus immune systemQ28140389
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-SrcQ28142620
RANK-L and RANK: T cells, bone loss, and mammalian evolutionQ28203468
Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritisQ28246778
A new mechanism of bone destruction in rheumatoid arthritis: synovial fibroblasts induce osteoclastogenesisQ28255805
TLR5, a novel mediator of innate immunity-induced osteoclastogenesis and bone lossQ28265502
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesisQ28293009
Cytokines in the pathogenesis of rheumatoid arthritisQ28303865
Autocrine regulation of interferon gamma in mesenchymal stem cells plays a role in early osteoblastogenesisQ28304548
Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.Q28506586
Immune complexes regulate bone metabolism through FcRγ signallingQ28512966
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signalingQ28513445
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Role of osteopontin in cellular signaling and toxicant injuryQ28594622
Osteoblastic cells regulate the haematopoietic stem cell nicheQ29615007
Identification of the haematopoietic stem cell niche and control of the niche sizeQ29615008
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandQ29619331
Interleukin-10 inhibits osteoclastogenesis by reducing NFATc1 expression and preventing its translocation to the nucleusQ33269870
Human osteoclast formation and bone resorption by monocytes and synovial macrophages in rheumatoid arthritisQ33579424
Role of osteopontin in amplification and perpetuation of rheumatoid synovitisQ33700555
The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.Q33794960
BCL6 is critical for the development of a diverse primary B cell repertoireQ33902336
Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.Q33966602
Generation and culture of osteoclastsQ34171862
T-lymphocytes enable osteoblast maturation via IL-17F during the early phase of fracture repairQ34328599
Efficient osteoclast differentiation requires local complement activationQ34374041
Osteopontin deficiency produces osteoclast dysfunction due to reduced CD44 surface expressionQ34451146
Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal nicheQ34516778
Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cellsQ34576335
Wnt signaling: a key regulator of bone massQ34583328
Abatacept treatment for rheumatoid arthritisQ34588972
DAP12 overexpression induces osteopenia and impaired early hematopoiesisQ34775668
Novel immunostimulatory effects of osteoclasts and macrophages on human γδ T cells.Q34906361
Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β.Q35172785
Requirement for NF-kappaB in osteoclast and B-cell developmentQ35199657
Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cellsQ40277201
Pax5-deficient mice exhibit early onset osteopenia with increased osteoclast progenitorsQ40489394
Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosionQ40590532
Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development.Q40646125
Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursorsQ40727130
IL-12 alone and in synergy with IL-18 inhibits osteoclast formation in vitroQ40814402
Osteopetrosis in mice lacking haematopoietic transcription factor PU.1.Q41121255
IL-10 critically modulates B cell responsiveness in Rankl-/- mice.Q41137165
Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op mouseQ41205540
Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclastsQ41773356
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destructionQ41927546
Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantationQ42219222
Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathwaysQ42494588
Bcl6 promotes osteoblastogenesis through Stat1 inhibitionQ42831214
Periodontitis in RA-the citrullinated enolase connection.Q42916208
Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environmentQ43181439
Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouseQ43681246
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritisQ44688981
Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblastsQ45325523
Increased serum IL-17 and IL-23 in the patient with ankylosing spondylitis.Q45905113
The role of RANKL (TRANCE/TNFSF11), a tumor necrosis factor family member, in skeletal development: effects of gene knockout and transgenic rescueQ46286533
Continuous RANKL inhibition in osteoprotegerin transgenic mice and rats suppresses bone resorption without impairing lymphorganogenesis or functional immune responsesQ46891798
TLR-3 enhances osteoclastogenesis through upregulation of RANKL expression from fibroblast-like synoviocytes in patients with rheumatoid arthritisQ47789840
Tendency towards erosive regression on magnetic resonance imaging at 12 months in rheumatoid arthritis patients treated with rituximabQ47820189
Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL.Q50335960
Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells.Q50912728
IL-4 suppresses osteoclast development and mature osteoclast function by a STAT6-dependent mechanism: irreversible inhibition of the differentiation program activated by RANKLQ51027178
Interferon-γ plays a role in bone formation in vivo and rescues osteoporosis in ovariectomized mice.Q51506098
Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints.Q51756072
The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.Q51949099
Osteoclasts support the survival of human plasma cells in vitro.Q51965738
Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification.Q52537176
Osteoclast-derived complement component 3a stimulates osteoblast differentiation.Q53069661
Regulatory T cells protect from local and systemic bone destruction in arthritis.Q53294686
The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.Q53453365
IL-6 signal blockade ameliorates the enhanced osteoclastogenesis and the associated joint destruction in a novel FcγRIIB-deficient rheumatoid arthritis mouse model.Q53464291
CTLA-4 directly inhibits osteoclast formationQ56900321
Treg cells suppress osteoclast formation: a new link between the immune system and boneQ56900960
Immune Interactions with CD4+ T Cells Promote the Development of Functional Osteoclasts from Murine CD11c+ Dendritic CellsQ57184758
Receptor Activator of NF- B Ligand and Osteoprotegerin Regulate Proinflammatory Cytokine Production in MiceQ57184804
Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiationQ57253491
Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trialQ57752107
Bone and haematopoietic defects in mice lacking c-fosQ58326969
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γQ59064307
Osteoimmunology and bone homeostasis: relevance to spondyloarthritisQ38109578
Osteoclasts in RA: diverse origins and functionsQ38111507
Immune cells and bone: coupling goes both ways.Q38134126
Tight relationships between B lymphocytes and the skeletal systemQ38204107
Role of IL-17 in the pathogenesis of psoriatic arthritis and axial spondyloarthritisQ38458004
Human CD4+CD25+ regulatory T cells inhibit the differentiation of osteoclasts from peripheral blood mononuclear cellsQ38506162
Osteoprotegerin, a crucial regulator of bone metabolism, also regulates B cell development and functionQ38525468
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerinQ39116155
The presence of IL-17+/FOXP3+ double-positive cells in periodontitisQ39361077
TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiationQ39645151
Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12.Q39669362
Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesisQ39714931
IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-kappaBQ39946703
Interleukin-10 inhibits RANKL-mediated expression of NFATc1 in part via suppression of c-Fos and c-Jun in RAW264.7 cells and mouse bone marrow cellsQ40107693
Inter-relationships between rheumatoid arthritis and periodontal disease. A review.Q35212215
IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activationQ35219971
B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal diseaseQ35222008
Glycosylation of immunoglobulin G determines osteoclast differentiation and bone lossQ35311994
Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilizationQ35441456
Parathyroid hormone: a double-edged sword for bone metabolismQ35703582
B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivoQ35804512
Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentinQ35913720
Mechanistic insight into osteoclast differentiation in osteoimmunologyQ36073894
Oncostatin m promotes mammary tumor metastasis to bone and osteolytic bone degradationQ36296474
Fos/AP-1 proteins in bone and the immune systemQ36324940
TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivoQ36375923
Osteopontin in Immune-mediated DiseasesQ36377677
TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factorQ36380989
Dendritic cells at the osteo-immune interface: implications for inflammation-induced bone loss.Q36757614
Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myelomaQ36915925
Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathwaysQ36964283
The role of NFAT in osteoclast formationQ37033696
Calcitonin: a drug of the past or for the future? Physiologic inhibition of bone resorption while sustaining osteoclast numbers improves bone qualityQ37164404
The role of Wnt proteins in arthritisQ37255748
Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgeneQ37265676
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiationQ37286240
Immune regulation of bone loss by Th17 cells.Q37317215
Regulation of dendritic cell survival and cytokine production by osteoprotegerinQ37362936
Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN-gamma in human osteoclast precursorsQ37438518
NF-κB signaling and bone resorptionQ37449635
Osteoimmunology and the effects of the immune system on boneQ37626412
Regulation of haematopoietic progenitor cell proliferation and survival: The involvement of the osteoblastQ37641682
Stromal cell-immune cell interactionsQ37809072
Signaling networks in RUNX2-dependent bone developmentQ37843947
Adverse effects of corticosteroids on bone metabolism: a reviewQ37875333
Interdependence of stromal and immune cells for lymph node functionQ37966310
Bone marrow niches for hematopoietic stem cells and immune cellsQ37997505
How vitamin D works on bone.Q38033260
P433issue12
P304page(s)1241-1258
P577publication date2016-09-20
P1433published inScience in China. Series C: Life SciencesQ2619480
P1476titleOsteoimmunology: memorandum for rheumatologists
P478volume59

Reverse relations

Q55410884Prevention and Treatment of Osteoporosis Using Chinese Medicinal Plants: Special Emphasis on Mechanisms of Immune Modulation.cites workP2860