| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Deborah L. Galson | Q51170712 |
| Steven R Goldring | Q114399448 | ||
| Ellen M Gravallese | Q117258216 | ||
| P2093 | author name string | P E Auron | |
| P2860 | cites work | Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation | Q22253232 |
| A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction | Q22254604 | ||
| Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation | Q24311588 | ||
| Osteoprotegerin: a novel secreted protein involved in the regulation of bone density | Q24313918 | ||
| TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells | Q24315251 | ||
| A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function | Q24336057 | ||
| RANK is essential for osteoclast and lymph node development | Q24598872 | ||
| osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification | Q24603266 | ||
| Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain | Q24604330 | ||
| Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand | Q24653311 | ||
| Crystallographic analysis of CD40 recognition and signaling by human TRAF2 | Q24675068 | ||
| Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL | Q24682139 | ||
| Three-dimensional structure of a complex between the death domains of Pelle and Tube | Q27620621 | ||
| Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation | Q27732032 | ||
| Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif | Q28138697 | ||
| AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation | Q28139447 | ||
| TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src | Q28142620 | ||
| Tec kinases: a family with multiple roles in immunity | Q28143522 | ||
| Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone | Q28241025 | ||
| RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis | Q28293009 | ||
| The interleukin 1 receptor: ligand interactions and signal transduction | Q28295124 | ||
| TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling | Q28513445 | ||
| Death deflected: IL-15 inhibits TNF-alpha-mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL-15Ralpha chain | Q28588631 | ||
| OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis | Q28589430 | ||
| Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death | Q28609905 | ||
| Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice | Q29547898 | ||
| The death domain kinase RIP mediates the TNF-induced NF-kappaB signal | Q29617727 | ||
| Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice | Q29618716 | ||
| Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand | Q29619331 | ||
| Evidence for a functional association between phosphatidylinositol 3-kinase and c-src in the spreading response of osteoclasts to colony-stimulating factor-1. | Q30169008 | ||
| A novel molecular mechanism modulating osteoclast differentiation and function | Q30643494 | ||
| The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. | Q33823576 | ||
| Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction | Q33886695 | ||
| The biology of Toll-like receptors | Q33922391 | ||
| Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase | Q33958468 | ||
| Interleukin-1 and tumor necrosis factor activities partially account for calvarial bone resorption induced by local injection of lipopolysaccharide | Q34001542 | ||
| Characterization of structural domains of human osteoclastogenesis inhibitory factor | Q34457751 | ||
| Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro | Q34459310 | ||
| Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice | Q35194925 | ||
| Requirement for NF-kappaB in osteoclast and B-cell development | Q35199657 | ||
| Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis | Q35764588 | ||
| TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor | Q36380989 | ||
| RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism | Q37108966 | ||
| Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor. | Q37372701 | ||
| Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin | Q39116155 | ||
| Membrane localization of TRAF 3 enables JNK activation | Q40904402 | ||
| CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFs | Q40955336 | ||
| Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines | Q41000781 | ||
| Tumor necrosis factor receptors types 1 and 2 differentially regulate osteoclastogenesis | Q42489909 | ||
| The erosive front: a topographic study of the junction between the pannus and the subchondral plate in the macerated rheumatoid metacarpal head | Q44063757 | ||
| Osteoclast-like cells in murine collagen induced arthritis | Q47957228 | ||
| Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2. | Q52192178 | ||
| Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. | Q52522634 | ||
| Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function. | Q53768934 | ||
| Induction of abundant osteoclast-like multinucleated giant cells in adjuvant arthritic rats with accompanying disordered high bone turnover. | Q54129470 | ||
| Chondroclasts and osteoclasts at subchondral sites of erosion in the rheumatoid joint | Q72824611 | ||
| Activated T lymphocytes support osteoclast formation in vitro | Q73149439 | ||
| Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts | Q73441763 | ||
| Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor | Q73490934 | ||
| Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis | Q73490940 | ||
| Expression of osteoclast differentiation factor at sites of bone erosion in collagen-induced arthritis | Q73678529 | ||
| The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation | Q73745042 | ||
| Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL) | Q73907464 | ||
| Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells | Q77484251 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | protein | Q8054 |
| intracellular receptor | Q117980 | ||
| glycoprotein | Q187126 | ||
| membrane protein | Q423042 | ||
| transport protein | Q2111029 | ||
| tumor necrosis factor receptor | Q2579343 | ||
| bone resorption | Q4941581 | ||
| membrane glycoprotein | Q6815130 | ||
| P304 | page(s) | 6-12 | |
| P577 | publication date | 2000-11-02 | |
| P1433 | published in | Arthritis Research | Q45128333 |
| P1476 | title | The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption | |
| P478 | volume | 3 |
| Q41986134 | A Biphasic Calcium Sulphate/Hydroxyapatite Carrier Containing Bone Morphogenic Protein-2 and Zoledronic Acid Generates Bone |
| Q33193230 | A flow cytometric method to detect protein-protein interaction in living cells by directly visualizing donor fluorophore quenching during CFP-->YFP fluorescence resonance energy transfer (FRET). |
| Q33766411 | A genetic variant in osteoprotegerin is associated with progression of joint destruction in rheumatoid arthritis |
| Q35091083 | Activation of interleukin 1beta gene transcription by human cytomegalovirus: molecular mechanisms and relevance to periodontitis |
| Q34452635 | Anticytokine therapy for osteoarthritis |
| Q36604460 | Arthritis suppressor genes TIA-1 and TTP dampen the expression of tumor necrosis factor alpha, cyclooxygenase 2, and inflammatory arthritis |
| Q90735853 | At the Crossroads of the Adipocyte and Osteoclast Differentiation Programs: Future Therapeutic Perspectives |
| Q36371110 | Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis |
| Q33691655 | Ethyl acetate fraction from Cudrania tricuspidata inhibits IL-1beta-stimulated osteoclast differentiation through downregulation of MAPKs, c-Fos and NFATc1 |
| Q40643961 | Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis |
| Q47396541 | Genetic Polymorphism of miR-196a-2 is Associated with Bone Mineral Density (BMD). |
| Q39784222 | Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer |
| Q43049903 | Joint erosion in rheumatoid arthritis: interactions between tumour necrosis factor alpha, interleukin 1, and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclasts |
| Q44068969 | Kinetics of bone protection by recombinant osteoprotegerin therapy in Lewis rats with adjuvant arthritis |
| Q34637340 | Lessons from animal models of arthritis |
| Q36586312 | MicroRNA variants as genetic determinants of bone mass |
| Q89818128 | Osteoclastogenesis in Periodontal Diseases: Possible Mediators and Mechanisms |
| Q46772299 | Osteoclastogenic activity during mandibular distraction osteogenesis |
| Q47657801 | Osteopenia in Siah1a mutant mice. |
| Q35068825 | Perspective of cytokine regulation for periodontal treatment: fibroblast biology |
| Q46777196 | Prostaglandin production by human gingival fibroblasts inhibited by triclosan in the presence of cetylpyridinium chloride |
| Q33759501 | RANK/RANKL/OPG system in the intervertebral disc |
| Q41912868 | RANKL cytokine enhances TNF-induced osteoclastogenesis independently of TNF receptor associated factor (TRAF) 6 by degrading TRAF3 in osteoclast precursors |
| Q40606140 | RNA aptamers selected against the receptor activator of NF-kappaB acquire general affinity to proteins of the tumor necrosis factor receptor family |
| Q35179608 | T-cell involvement in osteoclast biology: implications for rheumatoid bone erosion |
| Q24292181 | T2BP, a novel TRAF2 binding protein, can activate NF-kappaB and AP-1 without TNF stimulation |
| Q30743828 | TNF ligands and receptors in autoimmunity: an update |
| Q35143919 | TNF-receptor-associated factors as targets for drug development |
| Q36972287 | TRAF molecules in cell signaling and in human diseases |
| Q30159856 | TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src. |
| Q54765245 | The receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenic pathway is elevated in amelogenin-null mice. |
| Q37430478 | The role of osteoprotegerin (OPG) and estrogen receptor (ER-α) gene polymorphisms in rheumatoid arthritis. |
| Q38792670 | Transcriptome analysis of the regenerating tail vs. the scarring limb in lizard reveals pathways leading to successful vs. unsuccessful organ regeneration in amniotes. |
| Q80463776 | [Bone metabolism: molecular mechanisms] |
| Q53066088 | [Fibroblastic modulators of bone destruction]. |
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