Osteoclast fusion and regulation by RANKL-dependent and independent factors

scientific article published on December 2012

Osteoclast fusion and regulation by RANKL-dependent and independent factors is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.5312/WJO.V3.I12.212
P8608Fatcat IDrelease_rzq2rqqglze7xc7ggur5aefene
P932PMC publication ID3557323
P698PubMed publication ID23362465
P5875ResearchGate publication ID235383738

P2093author name stringYan Xiu
Lianping Xing
Brendan F Boyce
P2860cites workDC-STAMP, a novel multimembrane-spanning molecule preferentially expressed by dendritic cellsQ24290803
Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritisQ24564656
RANK is essential for osteoclast and lymph node developmentQ24598872
Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal developmentQ24616861
DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic featuresQ24672682
Impaired differentiation of osteoclasts in TREM-2-deficient individualsQ24672735
p300 functions as a transcriptional coactivator for the TAL1/SCL oncoproteinQ28144577
Matrix-embedded cells control osteoclast formationQ28247746
Evidence for osteocyte regulation of bone homeostasis through RANKL expressionQ28247757
Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesisQ28267970
Interleukin-32: a cytokine and inducer of TNFalphaQ28303648
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel functionQ28305026
RANKL-induced DC-STAMP is essential for osteoclastogenesisQ28504881
DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cellsQ28506839
Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCLQ28508494
Osteoclast stimulatory transmembrane protein (OC-STAMP), a novel protein induced by RANKL that promotes osteoclast differentiationQ28511207
The intracellular domain of CD44 promotes the fusion of macrophagesQ28577304
ADAM8 enhances osteoclast precursor fusion and osteoclast formation in vitro and in vivoQ28587581
ADAM8: a novel osteoclast stimulating factorQ28588620
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Role of DC-STAMP in cellular fusion of osteoclasts and macrophage giant cellsQ28589731
Shared principles in NF-kappaB signalingQ29547234
Genetic regulation of osteoclast development and functionQ29617421
Regulation of resting intracellular Ca(2+) concentration of ventricular myocytes by beta(3)-adrenoceptor and its signaling pathway in rats with experimental heart failureQ33499592
The role of calcium release activated calcium channels in osteoclast differentiationQ33608899
Osteoprotegerin ligand: a common link between osteoclastogenesis, lymph node formation and lymphocyte development.Q33611312
Identification of an inducible surface molecule specific to fusing macrophagesQ33656414
NIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysisQ33768994
MFR, a putative receptor mediating the fusion of macrophagesQ33781252
Specific cellular responses to alpha-tocopherolQ33950221
Recent advances in understanding the mechanisms of osteoclast precursor fusionQ34033604
Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP).Q34222920
NF-κB signaling participates in both RANKL- and IL-4-induced macrophage fusion: receptor cross-talk leads to alterations in NF-κB pathways.Q35147834
Requirement for NF-kappaB in osteoclast and B-cell developmentQ35199657
Orai1-mediated calcium entry plays a critical role in osteoclast differentiation and function by regulating activation of the transcription factor NFATc1Q35863762
Low-density lipoprotein receptor deficiency causes impaired osteoclastogenesis and increased bone mass in mice because of defect in osteoclastic cell-cell fusionQ36003737
An essential role for the association of CD47 to SHPS-1 in skeletal remodelingQ36058860
CD44 and beta3 integrin organize two functionally distinct actin-based domains in osteoclastsQ36173877
CD44 occupancy prevents macrophage multinucleationQ36288187
Osteoclast precursors, RANKL/RANK, and immunologyQ36324916
CD44 is a determinant of inflammatory bone lossQ36403383
TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral bloodQ36757010
Calcium signalling in lymphocyte activation and diseaseQ36912139
Calcium signalling and calcium transport in bone diseaseQ37056471
Osteoclast cell fusion: mechanisms and moleculesQ37143253
Essential role of DAP12 signaling in macrophage programming into a fusion-competent stateQ37171072
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.Q37178911
NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP).Q37302319
Macrophage fusion: molecular mechanismsQ37315593
Infantile malignant, autosomal recessive osteopetrosis: the rich and the poorQ37350732
NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanismQ37363042
Molecular mediators of macrophage fusionQ37592510
ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+ entry in the immune system and beyond.Q37597624
Regulation of osteoclast precursors in inflammatory bone loss.Q37624507
CCN family 2/connective tissue growth factor (CCN2/CTGF) promotes osteoclastogenesis via induction of and interaction with dendritic cell-specific transmembrane protein (DC-STAMP).Q38341546
Molecular analysis of RANKL-independent cell fusion of osteoclast-like cells induced by TNF-alpha, lipopolysaccharide, or peptidoglycanQ40195873
RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesisQ40271536
CTGF/Hcs24 interacts with the cytoskeletal protein actin in chondrocytesQ40684978
Sequential requirements for SCL/tal-1, GATA-2, macrophage colony-stimulating factor, and osteoclast differentiation factor/osteoprotegerin ligand in osteoclast developmentQ40866815
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signalingQ43142702
Effect of interleukin-32gamma on differentiation of osteoclasts from CD14+ monocytesQ43180966
NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesisQ44049672
Effect of CD44 deficiency on in vitro and in vivo osteoclast formationQ45172592
Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells.Q45986467
Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12.Q46112460
Development of foreign body giant cells in response to implantation of Spongostan as a scaffold for cartilage tissue engineeringQ47717867
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasisQ47761859
Regulatory mechanism of NFATc1 in RANKL-induced osteoclast activationQ48537793
Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL.Q50335960
RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis.Q51032592
Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.Q52192178
Vitamin E decreases bone mass by stimulating osteoclast fusion.Q53172611
The influence of interleukin-32γ on osteoclastogenesis with a focus on fusion-related genes.Q54551276
Induction of DC-STAMP by Alternative Activation and Downstream Signaling MechanismsQ57675118
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor geneQ59092154
Idiotype-cytokine fusion proteins as cancer vaccines. Relative efficacy of IL-2, IL-4, and granulocyte-macrophage colony-stimulating factorQ71656908
Two novel genes FIND and LIND differentially expressed in deactivated and Listeria-infected human macrophagesQ73857061
CD47, a ligand for the macrophage fusion receptor, participates in macrophage multinucleationQ74241718
Identities and differences in the metabolism of tocotrienols and tocopherols in HepG2 cellsQ78340427
Osteoclast formation is strongly reduced both in vivo and in vitro in the absence of CD47/SIRPalpha-interactionQ79382486
v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formationQ79383955
Abundant expression of tetraspanin CD9 in activated osteoclasts in ovariectomy-induced osteoporosis and in bone erosions of collagen-induced arthritisQ80695379
Osteoclast stimulatory transmembrane protein and dendritic cell–specific transmembrane protein cooperatively modulate cell–cell fusion to form osteoclasts and foreign body giant cellsQ83454126
Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMPQ85077877
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)212-222
P577publication date2012-12-01
P1433published inWorld journal of orthopedicsQ27724018
P1476titleOsteoclast fusion and regulation by RANKL-dependent and independent factors
P478volume3

Reverse relations

cites work (P2860)
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