Selective events in T cell development

scientific article published on January 1994

Selective events in T cell development is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1146/ANNUREV.IY.12.040194.003331
P8608Fatcat IDrelease_7pwgdmsg3rgunhywn76s25gle4
P698PubMed publication ID8011294

P2093author name stringFowlkes BJ
Robey E
P304page(s)675-705
P577publication date1994-01-01
P1433published inAnnual Review of ImmunologyQ567362
P1476titleSelective events in T cell development
P478volume12

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cites work (P2860)
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Q36367523CD81 expressed on human thymocytes mediates integrin activation and interleukin 2-dependent proliferation
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Q52208053Developmental changes predispose the fetal thymus to positive selection of CD4+CD8- T cells
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Q42944908Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development
Q52193174Differentiation of CD4(high)CD8(low) coreceptor-skewed thymocytes into mature CD8 single-positive cells independent of MHC class I recognition.
Q77328529Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire
Q36576967Drug insight: New immunomodulatory therapies in type 1 diabetes
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Q40056665Envelope glycoproteins of human immunodeficiency virus type 1: profound influences on immune functions
Q40973329Essential flexibility in the T-cell recognition of antigen
Q24321424Essential role for ZAP-70 in both positive and negative selection of thymocytes
Q77660091Evaluation of GM1 ganglioside-mediated apoptosis in feline thymocytes
Q72691884Evidence for a selective and multi-step model of T cell differentiation: CD4+CD8low thymocytes selected by a transgenic T cell receptor on major histocompatibility complex class I molecules
Q91935600Examining pathogenic concepts of autoimmune hepatitis for cues to future investigations and interventions
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Q28146131Expression of the Bcl-2 family member A1 is developmentally regulated in T cells
Q24655060Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain
Q77162637Functional properties of CD4+ CD28- T cells in the aging immune system
Q28591401Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis
Q36377257Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytes
Q36399540Galpha13 mediates a signal that is essential for proliferation and survival of thymocyte progenitors
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Q30156848Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection
Q33632733Growing up on the streets: why B-cell development differs from T-cell development
Q42913149HIV-1 Nef Disrupts Maturation of CD4+ T Cells through CD4/Lck Modulation
Q74086287Heterogeneity of the DN4 (CD44-CD25-) subset of CD4-CD8- double negative thymocytes; dependence on CD3 signaling
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Q45345198Notch activity influences the alphabeta versus gammadelta T cell lineage decision
Q37419676Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors
Q35219642Notch regulates cytolytic effector function in CD8+ T cells.
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Q33930556Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptide
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Q36735976Perturbation of the T cell repertoire in rheumatoid arthritis
Q48040399Pertussis toxin can replace T cell receptor signals that induce positive selection of CD8 T cells
Q51090801Positive selection as a developmental progression initiated by alpha beta TCR signals that fix TCR specificity prior to lineage commitment.
Q36366715Positive selection is not required for thymic maturation of transgenic gamma delta T cells
Q41049039Positive selection of CD4+ and CD8+ T cells
Q34703733Positive selection of invariant V alpha 14+ T cells by non-major histocompatibility complex-encoded class I-like molecules expressed on bone marrow-derived cells
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Q36376530Quantitative impact of thymic clonal deletion on the T cell repertoire
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Q35621984Regulatory T cells for tolerance therapy: revisiting the concept
Q35199657Requirement for NF-kappaB in osteoclast and B-cell development
Q36367266Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection
Q36369531Requirement for transforming growth factor beta1 in controlling T cell apoptosis
Q36401626Requirement of CD3 complex-associated signaling functions for expression of rearranged T cell receptor beta VDJ genes in early thymic development
Q36370544Restricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection
Q28585313RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development
Q36376884Role of the multiple T cell receptor (TCR)-zeta chain signaling motifs in selection of the T cell repertoire
Q33783983Selecting and maintaining a diverse T-cell repertoire
Q34162002Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
Q41642426Serological identification of human tumor antigens
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Q43809060Signaling checkpoints during the development of T lymphocytes
Q37408424Soluble γc cytokine receptor suppresses IL-15 signaling and impairs iNKT cell development in the thymus
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Q40379095T cell development in CD3-zeta mutant mice
Q36400581T cell development in mice lacking all T cell receptor zeta family members (Zeta, eta, and FcepsilonRIgamma).
Q36380948T cell receptor (TCR)-induced death of immature CD4+CD8+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus
Q40438235T cell receptor antagonists and partial agonists
Q35745491T cell receptor signaling that regulates the development of intrathymic natural regulatory T cells
Q36364509T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection.
Q35131705T cells develop normally in the absence of both Deltex1 and Deltex2
Q38923163T cells recognizing a 11mer influenza peptide complexed to H-2D(b) show promiscuity for peptide length.
Q35751012T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex.
Q35068900T-cell activation: the power of one.
Q59087078T-cell apoptosis detected in situ during positive and negative selection in the thymus
Q34659128T-cell development and the CD4-CD8 lineage decision
Q71079176TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck
Q44308973TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
Q43436449TCR v(beta) repertoire restriction and lack of CDR3 conservation implicate TCR-superantigen interactions in promoting the clonal evolution of murine thymic lymphomas
Q41514626TCR zeta chain in T cell development and selection
Q28589031TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation
Q36368982Tec family kinases modulate thresholds for thymocyte development and selection
Q74460598The CD8alphabeta co-receptor on double-positive thymocytes binds with differing affinities to the products of distinct class I MHC loci
Q34418401The MHC reactivity of the T cell repertoire prior to positive and negative selection.
Q34297955The T cell receptor for antigen: signaling and ligand discrimination
Q34576500The course of malaria in mice: major histocompatibility complex (MHC) effects, but no general MHC heterozygote advantage in single-strain infections
Q51081581The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate.
Q46118331The function of the CD4 coreceptor in the development of T cells
Q37218062The immunopathogenesis of myasthenia gravis
Q46660975The influence of the MAPK pathway on T cell lineage commitment
Q53653317The influence of the thymic environment on the CD4-versus-CD8 T lineage decision.
Q71118244The myelin basic protein-specific T cell repertoire in (transgenic) Lewis rat/SCID mouse chimeras: preferential V beta 8.2 T cell receptor usage depends on an intact Lewis thymic microenvironment
Q53600866The quantitative assessment of MHC II on thymic epithelium: implications in cortical thymocyte development.
Q46273713The role of short homology repeats and TdT in generation of the invariant gamma delta antigen receptor repertoire in the fetal thymus.
Q43186206The small GTPase RhoH is an atypical regulator of haematopoietic cells
Q72333288The survival and turnover of mature and immature CD8 T cells
Q33942101The thymus and negative selection
Q34770393The unconventional lifestyle of NKT cells
Q41546347Thymic dendritic cells
Q74171897Thymic function can be accurately monitored by the level of recent T cell emigrants in the circulation
Q33697134Thymic nurse cells exhibit epithelial progenitor phenotype and create unique extra-cytoplasmic membrane space for thymocyte selection
Q35086645Thymic nurse cells: a microenvironment for thymocyte development and selection
Q41361316Thymic stromal cell specialization and the T-cell receptor repertoire
Q73043249Thymic stromal organization is regulated by the specificity of T cell receptor/major histocompatibility complex interactions
Q77719583Thymocyte differentiation: it's time to bend a little
Q36375680Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47
Q41717817Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3.
Q36367667Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage
Q42549632Thymosin alpha 1 antagonizes dexamethasone and CD3-induced apoptosis of CD4+ CD8+ thymocytes through the activation of cAMP and protein kinase C dependent second messenger pathways
Q47230335Thymosin alpha(1) application augments immune response and down-regulates tumor weight and organ colonization in BALB/c-mice
Q73343719Thymosin alpha1 is a time and dose-dependent antagonist of dexamethasone-induced apoptosis of murine thymocytes in vitro
Q35794622Transcriptional control of thymocyte positive selection
Q35964040Transient up-regulation of P2Y2 nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes
Q42026939Transitional B cells are the target of negative selection in the B cell compartment
Q34335562Transplantation tolerance induced by mixed chimerism
Q40922234Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.
Q36366238Unresponsiveness to a self-peptide of mouse lysozyme owing to hindrance of T cell receptor-major histocompatibility complex/peptide interaction caused by flanking epitopic residues
Q42151381Upregulation of surface markers on dying thymocytes
Q36401327Visualization of CD4/CD8 T cell commitment
Q30448775c-Myb is essential for early T cell development
Q34069619c-Rel controls multiple discrete steps in the thymic development of Foxp3+ CD4 regulatory T cells
Q33590483c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells
Q24567874cAMP inducibility of transcriptional repressor ICER in developing and mature human T lymphocytes
Q41954424p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice

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