Signaling Pathways in Osteoclast Differentiation

scientific article

Signaling Pathways in Osteoclast Differentiation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4068/CMJ.2016.52.1.12
P3181OpenCitations bibliographic resource ID1495641
P932PMC publication ID4742606
P698PubMed publication ID26865996
P5875ResearchGate publication ID293010045

P2093author name stringNacksung Kim
Jung Ha Kim
P2860cites workJNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanismsQ58326878
c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodelingQ58326943
Possible involvement of IkappaB kinase 2 and MKK7 in osteoclastogenesis induced by receptor activator of nuclear factor kappaB ligandQ64378984
Administration of colony stimulating factor-1 corrects some macrophage, dental, and skeletal defects in an osteopetrotic mutation (toothless, tl) in the ratQ68117985
Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL)Q73907464
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1Q24300916
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
The PI3K-PDK1 connection: more than just a road to PKBQ24531972
Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6Q24537518
RANK is essential for osteoclast and lymph node developmentQ24598872
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand familiesQ28137631
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient miceQ28140546
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-SrcQ28142620
Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survivalQ28142897
Identification of a second Grb2 binding site in the v-Fms tyrosine kinaseQ28255340
Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesisQ28267970
Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinaseQ28278061
The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptorQ28285539
Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systemsQ28294477
SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclastsQ28510858
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signalingQ28513445
Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptorsQ28513453
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Signaling to NF-kappaBQ29547844
Missing pieces in the NF-kappaB puzzleQ29547864
Genetic regulation of osteoclast development and functionQ29617421
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclastsQ29618116
NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubismQ30157499
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouseQ33646429
Early events in M-CSF receptor signalingQ33855769
TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRsQ33864629
Sequential activation of phoshatidylinositol 3-kinase and phospholipase C-gamma2 by the M-CSF receptor is necessary for differentiation signalingQ33887555
Both src-dependent and -independent mechanisms mediate phosphatidylinositol 3-kinase regulation of colony-stimulating factor 1-activated mitogen-activated protein kinases in myeloid progenitorsQ33965534
A CSF-1 Receptor Phosphotyrosine 559 Signaling Pathway Regulates Receptor Ubiquitination and Tyrosine PhosphorylationQ34489187
Biology of the TRANCE axisQ35145622
Requirement for NF-kappaB in osteoclast and B-cell developmentQ35199657
Erk1 positively regulates osteoclast differentiation and bone resorptive activityQ35227805
T-cell receptor signal transmission: who gives an ITAM?Q35557286
Osteoclasts: New InsightsQ35755039
Macrophage proliferation is regulated through CSF-1 receptor tyrosines 544, 559, and 807.Q35922299
The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesisQ36371653
Tumor necrosis factor receptor-associated factor 6 (TRAF6) stimulates extracellular signal-regulated kinase (ERK) activity in CD40 signaling along a ras-independent pathway.Q36400170
I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone lossQ36402985
Bone quality--the material and structural basis of bone strength and fragilityQ36488553
CSF-1 receptor structure/function in MacCsf1r-/- macrophages: regulation of proliferation, differentiation, and morphologyQ36838570
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinaseQ37647341
Colony-stimulating factor-1 receptorQ37870336
Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-FosQ38342636
Akt induces osteoclast differentiation through regulating the GSK3β/NFATc1 signaling cascadeQ38467858
Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesisQ39714931
Parallel signal processing among mammalian MAPKsQ40501929
PTEN regulates RANKL- and osteopontin-stimulated signal transduction during osteoclast differentiation and cell motilityQ40686068
Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signalingQ40756889
CSF-I signal transduction: what is of functional significance?Q41546313
Autoamplification of NFATc1 expression determines its essential role in bone homeostasisQ42972503
Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defectsQ43833399
p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast functionQ44072080
Tyrosines 559 and 807 in the cytoplasmic tail of the macrophage colony-stimulating factor receptor play distinct roles in osteoclast differentiation and functionQ44226046
Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesisQ46620740
Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.Q46711436
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasisQ47761859
Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.Q52192178
c-Fms Tyrosine 559 Is a Major Mediator of M-CSF-induced Proliferation of Primary MacrophagesQ58085242
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)12-7
P577publication date2016-01-01
P1433published inChonnam Medical JournalQ26842647
P1476titleSignaling Pathways in Osteoclast Differentiation
P478volume52

Reverse relations

cites work (P2860)
Q36195181Association of Serum Osteoprotegerin Levels with Bone Loss in Chronic Kidney Disease: Insights from the KNOW-CKD Study
Q90653768Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL-induced osteoclastogenesis
Q64237120Black Rice ( L.) Fermented with Attenuates Osteoclastogenesis and Ovariectomy-Induced Osteoporosis
Q91967069Creation of RANKL mutants with low affinity for decoy receptor OPG and their potential anti-fibrosis activity
Q90347790Deep Learning Implicitly Handles Tissue Specific Phenomena to Predict Tumor DNA Accessibility and Immune Activity
Q36939350Downregulation of Runx2 by 1,25-Dihydroxyvitamin D₃ Induces the Transdifferentiation of Osteoblasts to Adipocytes
Q38744409Effects of Dihydrophaseic Acid 3'-O-β-d-Glucopyranoside Isolated from Lycii radicis Cortex on Osteoblast Differentiation
Q90745020F2r negatively regulates osteoclastogenesis through inhibiting the Akt and NFκB signaling pathways
Q90567724From Osteoclast Differentiation to Osteonecrosis of the Jaw: Molecular and Clinical Insights
Q37351205GATA4 negatively regulates bone sialoprotein expression in osteoblasts
Q90290403Hexane Fraction of Turbo brunneus Inhibits Intermediates of RANK-RANKL Signaling Pathway and Prevent Ovariectomy Induced Bone Loss
Q64262538I-BET151 suppresses osteoclast formation and inflammatory cytokines secretion by targetting BRD4 in multiple myeloma
Q64085314Interleukin-27 prevents LPS-induced inflammatory osteolysis by inhibiting osteoclast formation and function
Q90474952Isosteviol Derivative Inhibits Osteoclast Differentiation and Ameliorates Ovariectomy-Induced Osteoporosis
Q89977149METTL3 Modulates Osteoclast Differentiation and Function by Controlling RNA Stability and Nuclear Export
Q58588319Madecassoside inhibits estrogen deficiency-induced osteoporosis by suppressing RANKL-induced osteoclastogenesis
Q63762081Mandibular Bone Loss after Masticatory Muscles Intervention with Botulinum Toxin: An Approach from Basic Research to Clinical Findings
Q37729189Methyl Gallate Inhibits Osteoclast Formation and Function by Suppressing Akt and Btk-PLCγ2-Ca2+ Signaling and Prevents Lipopolysaccharide-Induced Bone Loss.
Q47796713Novel RANKL DE-loop mutants antagonize RANK-mediated osteoclastogenesis
Q39190775Osteoblast-osteoclast interactions
Q49907069Paeoniflorin ameliorates collagen-induced arthritis via suppressing NF-κB signaling pathway in osteoclast differentiation.
Q60907427Prostate Osteoblast-Like Cells: A Reliable Prognostic Marker of Bone Metastasis in Prostate Cancer Patients
Q37472044RCANs regulate the convergent roles of NFATc1 in bone homeostasis
Q42371581Real-time in vivo imaging of metastatic bone tumors with a targeted near-infrared fluorophore
Q90659616Regulation of TRPV5 transcription and expression by E2/ERα signalling contributes to inhibition of osteoclastogenesis
Q92377250Rev-erbα Negatively Regulates Osteoclast and Osteoblast Differentiation through p38 MAPK Signaling Pathway
Q37148066STAT5 is a key transcription factor for IL-3-mediated inhibition of RANKL-induced osteoclastogenesis
Q89619982Signaling of the Purinergic System in the Joint
Q37330422Smad4 is required to inhibit osteoclastogenesis and maintain bone mass
Q58696619Tetrahydroxystilbene Glucoside Regulates Proliferation, Differentiation, and OPG/RANKL/M-CSF Expression in MC3T3-E1 Cells via the PI3K/Akt Pathway
Q92664754The IRF2BP2-KLF2 axis regulates osteoclast and osteoblast differentiation
Q42378776The effects of downhill and uphill exercise training on osteogenesis-related factors in ovariectomy-induced bone loss
Q58586122Thy-1 Deficiency Augments Bone Loss in Obesity by Affecting Bone Formation and Resorption
Q42197175Tusc2/Fus1 regulates osteoclast differentiation through NF-κB and NFATc1.
Q90599354Umbelliferone Prevents Lipopolysaccharide-Induced Bone Loss and Suppresses RANKL-Induced Osteoclastogenesis by Attenuating Akt-c-Fos-NFATc1 Signaling
Q53733846[Effects of paeonol on the function of bone marrow-derived macrophage from Porphyromonas gingivalis-induced mice].

Search more.