review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Sophie Roux | Q91307971 |
P2093 | author name string | Michèle Roy | |
P2860 | cites work | OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation | Q24295224 |
Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity | Q24300416 | ||
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery | Q24302549 | ||
Lysosomal positioning coordinates cellular nutrient responses. | Q42160015 | ||
Leucine-Rich Repeat Kinase 1 Regulates Autophagy through Turning On TBC1D2-Dependent Rab7 Inactivation | Q42416558 | ||
Endocytic pathway from the basal plasma membrane to the ruffled border membrane in bone-resorbing osteoclasts | Q42443064 | ||
Autophagy and 3-Phosphoinositide-Dependent Kinase 1 (PDK1)-Related Kinome in Pagetic Osteoclasts | Q42488670 | ||
Involvement of kinase PKC-zeta in the p62/p62(P392L)-driven activation of NF-κB in human osteoclasts | Q42518301 | ||
Autophagy: a key pathway of TNF-induced inflammatory bone loss | Q42561560 | ||
Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion | Q43192631 | ||
M-CSF, TNFα and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase | Q44591611 | ||
Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors | Q45151645 | ||
Osteoprotegerin decreases human osteoclast apoptosis by inhibiting the TRAIL pathway | Q47847762 | ||
Rab35 GTPase recruits NDP52 to autophagy targets | Q47894144 | ||
The small GTPase RAB37 functions as an organizer for autophagosome biogenesis | Q48126298 | ||
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly | Q48138489 | ||
The RAB GTPase RAB18 modulates macroautophagy and proteostasis | Q50212467 | ||
Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2. | Q52192178 | ||
Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment. | Q52715407 | ||
Autophagy: a new player in skeletal maintenance? | Q53162347 | ||
Modulation of tumor necrosis factor related apoptosis-inducing ligand (TRAIL) receptors in a human osteoclast model in vitro. | Q53214880 | ||
Death receptors, Fas and TRAIL receptors, are involved in human osteoclast apoptosis. | Q53672361 | ||
Trafficking of Matrix Collagens Through Bone-Resorbing Osteoclasts | Q56341625 | ||
Expression and Regulation of RAB3 Proteins in Osteoclasts and Their Precursors | Q58085560 | ||
c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling | Q58326943 | ||
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene | Q59092154 | ||
Autophagy regulates hypoxia-induced osteoclastogenesis through the HIF-1α/BNIP3 signaling pathway | Q64379818 | ||
Osteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake | Q78859808 | ||
M-CSF, c-Fms, and signaling in osteoclasts and their precursors | Q79872859 | ||
Rab GTPases at a glance | Q81566767 | ||
Microtubule-associated protein light chain 3 regulates Cdc42-dependent actin ring formation in osteoclast | Q83783270 | ||
Function of alternative splicing | Q84837505 | ||
Protrudin induces neurite formation by directional membrane trafficking | Q24311681 | ||
Network organization of the human autophagy system | Q24324004 | ||
TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes | Q24324535 | ||
Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation | Q24336821 | ||
TBC1D5 and the AP2 complex regulate ATG9 trafficking and initiation of autophagy | Q24338806 | ||
Paget disease of bone: mapping of two loci at 5q35-qter and 5q31. | Q24535825 | ||
Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6 | Q24537518 | ||
RANK is essential for osteoclast and lymph node development | Q24598872 | ||
The Ras protein superfamily: evolutionary tree and role of conserved amino acids | Q24603374 | ||
Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans | Q24673342 | ||
Cellular functions of Rab GTPases at a glance | Q26798421 | ||
Rab GTPase regulation of membrane identity | Q26823807 | ||
Regulation of small GTPases by GEFs, GAPs, and GDIs | Q26825750 | ||
PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins | Q27696844 | ||
Rab GTPases as coordinators of vesicle traffic | Q28131746 | ||
Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif | Q28138697 | ||
Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man | Q28201425 | ||
Intracellular membrane trafficking pathways in bone-resorbing osteoclasts revealed by cloning and subcellular localization studies of small GTP-binding rab proteins | Q28202948 | ||
Bisphosphonates: from bench to bedside | Q28251212 | ||
Removal of osteoclast bone resorption products by transcytosis | Q28307077 | ||
Carbonic anhydrase II deficiency in 12 families with the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification | Q28307228 | ||
Downregulation of small GTPase Rab7 impairs osteoclast polarization and bone resorption | Q28576916 | ||
Possible role of direct Rac1-Rab7 interaction in ruffled border formation of osteoclasts | Q28584020 | ||
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis | Q28589430 | ||
TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation | Q29030353 | ||
Genome-wide association identifies three new susceptibility loci for Paget's disease of bone. | Q29417073 | ||
Osteoclast differentiation and activation | Q29547556 | ||
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice | Q29547898 | ||
Rab3D regulates a novel vesicular trafficking pathway that is required for osteoclastic bone resorption | Q30475918 | ||
Cisternal rab proteins regulate Golgi apparatus redistribution in response to hypotonic stress | Q33768599 | ||
Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298. | Q33913012 | ||
Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts | Q33939357 | ||
Thousands of rab GTPases for the cell biologist | Q34055251 | ||
Alternative splicing in osteoclasts and Paget's disease of bone | Q34085047 | ||
Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35 | Q34113018 | ||
TBC proteins: GAPs for mammalian small GTPase Rab? | Q34159986 | ||
Ubiquitination and selective autophagy | Q34283289 | ||
Amino acid signalling upstream of mTOR | Q34325138 | ||
Osteopetrosis | Q34380528 | ||
The integration of autophagy and cellular trafficking pathways via RAB GAPs | Q34501618 | ||
Toward a comprehensive map of the effectors of rab GTPases | Q34513353 | ||
The Roles of Small GTPases in Osteoclast Biology | Q34975336 | ||
Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function. | Q35107102 | ||
Requirement for NF-kappaB in osteoclast and B-cell development | Q35199657 | ||
Rab GTPases as regulators of endocytosis, targets of disease and therapeutic opportunities | Q35278147 | ||
Osteoclast precursor differentiation by MCPIP via oxidative stress, endoplasmic reticulum stress, and autophagy | Q35602113 | ||
Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice | Q35607627 | ||
Autophagy proteins regulate the secretory component of osteoclastic bone resorption | Q35629038 | ||
TRAFD1 (FLN29) Interacts with Plekhm1 and Regulates Osteoclast Acidification and Resorption | Q35636047 | ||
Golgi-Resident GTPase Rab30 Promotes the Biogenesis of Pathogen-Containing Autophagosomes. | Q35895316 | ||
Paget disease of bone | Q36029217 | ||
The collection of NFATc1-dependent transcripts in the osteoclast includes numerous genes non-essential to physiologic bone resorption | Q36275737 | ||
Rab13 is upregulated during osteoclast differentiation and associates with small vesicles revealing polarized distribution in resorbing cells | Q36285866 | ||
alphavbeta3 and macrophage colony-stimulating factor: partners in osteoclast biology | Q36324934 | ||
Thematic review series: lipid posttranslational modifications. geranylgeranylation of Rab GTPases. | Q36364319 | ||
Recent advances in understanding the mechanism of action of bisphosphonates | Q36464893 | ||
Signal integration and diversification through the p62 scaffold protein | Q36686435 | ||
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice | Q36791739 | ||
Genetics and aetiology of Pagetic disorders of bone | Q37116332 | ||
Rho GTPases in osteoclasts: orchestrators of podosome arrangement | Q37147506 | ||
Vesicular trafficking in osteoclasts | Q37259741 | ||
Intracellular Trafficking Network of Protein Nanocapsules: Endocytosis, Exocytosis and Autophagy | Q37291277 | ||
PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis. | Q37351613 | ||
TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation. | Q37407944 | ||
The p62 P392L mutation linked to Paget's disease induces activation of human osteoclasts | Q37578050 | ||
Rab27A regulates transport of cell surface receptors modulating multinucleation and lysosome-related organelles in osteoclasts. | Q37738764 | ||
Rab protein evolution and the history of the eukaryotic endomembrane system | Q37768044 | ||
Rab7: Role of its protein interaction cascades in endo-lysosomal traffic | Q37790159 | ||
Regulation of mammalian autophagy in physiology and pathophysiology. | Q37801517 | ||
The regulation of osteoclast function and bone resorption by small GTPases | Q37903263 | ||
Canonical and non-canonical autophagy: variations on a common theme of self-eating? | Q37968154 | ||
The adaptor protein p62/SQSTM1 in osteoclast signaling pathways | Q37973113 | ||
Illuminating the functional and structural repertoire of human TBC/RABGAPs. | Q37976530 | ||
Osteoclast-derived coupling factors in bone remodeling | Q38108750 | ||
The autophagic roles of Rab small GTPases and their upstream regulators: a review | Q38219095 | ||
Rab proteins: the key regulators of intracellular vesicle transport | Q38236498 | ||
TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic | Q38259308 | ||
Endocytosis and the Src family of non-receptor tyrosine kinases | Q38265286 | ||
Autophagy and proteins involved in vesicular trafficking | Q38602885 | ||
p62 is a key regulator of nutrient sensing in the mTORC1 pathway. | Q38666713 | ||
Rab44, a novel large Rab GTPase, negatively regulates osteoclast differentiation by modulating intracellular calcium levels followed by NFATc1 activation | Q38695357 | ||
Multiple Types of Guanine Nucleotide Exchange Factors (GEFs) for Rab Small GTPases. | Q38849657 | ||
Spatial distribution of phagolysosomes is independent of the regulation of lysosome position by Rab34. | Q39123055 | ||
Roles for RAB24 in autophagy and disease | Q39278100 | ||
Proteasome inhibitors impair RANKL-induced NF-kappaB activity in osteoclast-like cells via disruption of p62, TRAF6, CYLD, and IkappaBalpha signaling cascades | Q39861170 | ||
Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4. | Q40326577 | ||
Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone. | Q40453402 | ||
A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates | Q41122422 | ||
TBC1D20 mediates autophagy as a key regulator of autophagosome maturation | Q41575670 | ||
Osteoclasts express high levels of pp60c-src in association with intracellular membranes | Q41774224 | ||
The TBC/RabGAP Armus coordinates Rac1 and Rab7 functions during autophagy. | Q41885196 | ||
Phosphorylation of the exchange factor DENND3 by ULK in response to starvation activates Rab12 and induces autophagy | Q41904754 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | peptide | Q172847 |
cell | Q7868 | ||
enzyme | Q8047 | ||
P304 | page(s) | 4541538 | |
P577 | publication date | 2018-08-15 | |
P1433 | published in | BioMed Research International | Q17509958 |
P1476 | title | Rab GTPases in Osteoclastic Endomembrane Systems | |
P478 | volume | 2018 |
Q64060632 | Membrane trafficking in osteoclasts and implications for osteoporosis | cites work | P2860 |
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