Osteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake

scientific article published on 01 February 2003

Osteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1034/J.1600-0854.2003.40206.X
P698PubMed publication ID12559037

P2093author name stringHaibo Zhao
H Kalervo Väänänen
Mika T K Mulari
Päivi T Lakkakorpi
P2860cites workGelsolin inhibition of fast axonal transport indicates a requirement for actin microfilamentsQ41544632
The endocytic machinery in nerve terminals surrounds sites of exocytosisQ41710112
A novel class of clathrin-coated vesicles budding from endosomesQ41811118
Vitronectin receptor has a role in bone resorption but does not mediate tight sealing zone attachment of osteoclasts to the bone surfaceQ42214201
Lack of vacuolar proton ATPase association with the cytoskeleton in osteoclasts of osteosclerotic (oc/oc) miceQ42528957
Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclastsQ42762796
Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubulesQ45158799
Role of Drosophila alpha-adaptin in presynaptic vesicle recyclingQ47071592
Electron microscopy of developing calvaria reveals images that suggest that osteoclasts engulf and destroy osteocytes during bone resorptionQ47577650
A comparative study of disaggregated chick and rat osteoclasts in vitro: effects of calcitonin and prostaglandins.Q50904651
Kinetics of the osteoclast cytoskeleton during the resorption cycle in vitro.Q54258542
Trafficking of Matrix Collagens Through Bone-Resorbing OsteoclastsQ56341625
Actin-dependent organelle movement in squid axoplasmQ59065813
The distribution of podosomes in osteoclasts cultured on bone laminae: effect of retinolQ67975369
Immunoperoxidase methods for the localization of antigens in cultured cells and tissue sections by electron microscopyQ69536948
Resorption of dentine by isolated osteoclasts in vitroQ70933063
Osteoclast integrin alphaVbeta3 is present in the clear zone and contributes to cellular polarizationQ71801722
Rab GTPases in vesicular transportQ72648535
Interaction between vacuolar H(+)-ATPase and microfilaments during osteoclast activationQ73041211
Clathrin-mediated endocytosis near active zones in snake motor boutonsQ73119689
Ultrastructural and lanthanum tracer examination of rapidly resorbing rat alveolar bone suggests that osteoclasts internalize dying bone cellsQ74676495
Study of immunoelectron microscopic localization of cathepsin K in osteoclasts and other bone cells in the mouse femurQ77690449
Endocytic active zones: hot spots for endocytosis in vertebrate neuromuscular terminalsQ77874533
Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartmentsQ24316079
Osteopontin--a possible anchor of osteoclasts to boneQ24558077
Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymesQ24675937
Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependentQ24678109
The amino-terminal domain of the B subunit of vacuolar H+-ATPase contains a filamentous actin binding siteQ28142113
Clathrin and adaptorsQ28280468
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiencyQ28284581
Localization of cathepsin K in human osteoclasts by in situ hybridization and immunohistochemistryQ28303355
Removal of osteoclast bone resorption products by transcytosisQ28307077
Downregulation of small GTPase Rab7 impairs osteoclast polarization and bone resorptionQ28576916
Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11Q29615018
The diversity of Rab proteins in vesicle transportQ29620216
The role of dynamin and its binding partners in coated pit invagination and scissionQ30168371
Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zoneQ30175877
GTPase activity of dynamin and resulting conformation change are essential for endocytosisQ32165116
"Kiss and run" exocytosis at hippocampal synapsesQ33922918
Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junctionQ34207383
Turnover of transmitter and synaptic vesicles at the frog neuromuscular junctionQ34207387
Osteoclastic bone resorption by a polarized vacuolar proton pumpQ34441726
The biogenesis and functions of exosomesQ34609715
Organization of osteoclast microfilaments during the attachment to bone surface in vitro.Q35938974
Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structuresQ36211236
Polarized secretion of lysosomal enzymes: co-distribution of cation-independent mannose-6-phosphate receptors and lysosomal enzymes along the osteoclast exocytic pathwayQ36219001
Rab 7: an important regulator of late endocytic membrane trafficQ36236377
AP-2-containing clathrin coats assemble on mature lysosomesQ36257719
Traffic of dynamin within individual Drosophila synaptic boutons relative to compartment-specific markers.Q36813636
Beta 1 integrins and osteoclast function: involvement in collagen recognition and bone resorptionQ36829818
Clear zone in osteoclast function: role of podosomes in regulation of bone-resorbing activityQ37202816
PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinaseQ37384701
P433issue2
P304page(s)113-125
P577publication date2003-02-01
P1433published inTrafficQ1572846
P1476titleOsteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake
P478volume4

Reverse relations

cites work (P2860)
Q53266240Aconitum pseudo-laeve var. erectum inhibits receptor activator of nuclear factor kappa-B ligand-induced osteoclastogenesis via the c-Fos/nuclear factor of activated T-cells, cytoplasmic 1 signaling pathway and prevents lipopolysaccharide-induced bon
Q34168605Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice
Q40521404Apatite-mediated actin dynamics in resorbing osteoclasts
Q92064508Cause and effect of microenvironmental acidosis on bone metastases
Q35956822Disruption of CXCR4 enhances osteoclastogenesis and tumor growth in bone
Q41990261Distinctive subdomains in the resorbing surface of osteoclasts
Q52779703Expression of typical osteoclast markers by PBMCs after PEG-induced fusion as a model for studying osteoclast differentiation.
Q92531098Flavonoids compounds from Tridax procumbens inhibit osteoclast differentiation by down-regulating c-Fos activation
Q37680016Hypoxia-Induced Fibroblast Growth Factor 11 Stimulates Osteoclast-Mediated Resorption of Bone.
Q34407027Imaging podosome dynamics and matrix degradation
Q91639069Immune Function and Diversity of Osteoclasts in Normal and Pathological Conditions
Q35107102Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function.
Q27334454In vitro model of bone to facilitate measurement of adhesion forces and super-resolution imaging of osteoclasts
Q39089584Increases in intracellular pH facilitate endocytosis and decrease availability of voltage-gated proton channels in osteoclasts and microglia
Q35085185Inhibition of osteoclast differentiation and bone resorption by N-methylpyrrolidone
Q35184299Intracellular membrane trafficking in bone resorbing osteoclasts
Q30491065Lysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts
Q36994689Membrane trafficking in osteoblasts and osteoclasts: new avenues for understanding and treating skeletal diseases
Q64060632Membrane trafficking in osteoclasts and implications for osteoporosis
Q42273508Novel perspectives on the transcytotic route in osteoclasts
Q36333959Pit- and trench-forming osteoclasts: a distinction that matters
Q34344623Podosome organization drives osteoclast-mediated bone resorption.
Q28581273Polarization and secretion of cathepsin K precede tartrate-resistant acid phosphatase secretion to the ruffled border area during the activation of matrix-resorbing clasts
Q36399967Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts
Q58776864Rab GTPases in Osteoclastic Endomembrane Systems
Q36285866Rab13 is upregulated during osteoclast differentiation and associates with small vesicles revealing polarized distribution in resorbing cells
Q30475918Rab3D regulates a novel vesicular trafficking pathway that is required for osteoclastic bone resorption
Q46665328Recombinant VSV G proteins reveal a novel raft-dependent endocytic pathway in resorbing osteoclasts
Q36895332Regulation of osteoclast polarization
Q26996000Regulation of osteoclasts by membrane-derived lipid mediators
Q57566198Septins are critical regulators of osteoclastic bone resorption
Q104569990Surface distribution of heterogenous clathrin assemblies in resorbing osteoclasts
Q30497922Surface-induced regulation of podosome organization and dynamics in cultured osteoclasts
Q35951743Targeting polymer therapeutics to bone
Q34975336The Roles of Small GTPases in Osteoclast Biology
Q55071353The Sealing Zone in Osteoclasts: A Self-Organized Structure on the Bone.
Q37903263The regulation of osteoclast function and bone resorption by small GTPases
Q33830438Time-lapse reveals that osteoclasts can move across the bone surface while resorbing
Q28506518V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption

Search more.