| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1047966588 |
| P356 | DOI | 10.1007/S00223-015-9967-7 |
| P932 | PMC publication ID | 4730947 |
| P698 | PubMed publication ID | 25712254 |
| P5875 | ResearchGate publication ID | 272841298 |
| P2093 | author name string | Jian Zhou | |
| Haibo Zhao | |||
| Shiqiao Ye | |||
| Xiaolin Li | |||
| Toshifumi Fujiwara | |||
| P2860 | cites work | Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1 | Q22306225 |
| Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss | Q24295008 | ||
| Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation | Q24311588 | ||
| LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation | Q24536102 | ||
| RANK is essential for osteoclast and lymph node development | Q24598872 | ||
| Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand | Q24653311 | ||
| Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL | Q24682139 | ||
| NOTCHing the bone: insights into multi-functionality. | Q37516656 | ||
| New insights into osteoclastogenic signaling mechanisms | Q38019255 | ||
| Endocytosis and control of Notch signaling | Q38028087 | ||
| Notch signaling and bone remodeling | Q38092026 | ||
| Osteoclast-derived coupling factors in bone remodeling | Q38108750 | ||
| Osteopetrosis: genetics, treatment and new insights into osteoclast function. | Q38123371 | ||
| Ligand of Numb proteins LNX1p80 and LNX2 interact with the human glycoprotein CD8α and promote its ubiquitylation and endocytosis. | Q39449307 | ||
| The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells. | Q39871522 | ||
| Notch is activated in RANKL-induced osteoclast differentiation and resorption | Q39977648 | ||
| Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts | Q40862968 | ||
| Numb localizes at endosomes and controls the endosomal sorting of notch after asymmetric division in Drosophila | Q42436142 | ||
| Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts | Q42918767 | ||
| Calcium/calmodulin-dependent protein kinase IV (CaMKIV) enhances osteoclast differentiation via the up-regulation of Notch1 protein stability | Q44452361 | ||
| Phosphatidylinositol 3-kinase coordinately activates the MEK/ERK and AKT/NFkappaB pathways to maintain osteoclast survival | Q47982674 | ||
| NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. | Q50878030 | ||
| Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2. | Q52192178 | ||
| Notch signaling: numb makes the difference. | Q52734603 | ||
| Numb inhibits the recycling of Sanpodo in Drosophila sensory organ precursor. | Q52753700 | ||
| Ligand-of-Numb protein X is an endocytic scaffold for junctional adhesion molecule 4. | Q54592882 | ||
| JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms | Q58326878 | ||
| The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene | Q59092154 | ||
| Stimulation of osteoblastic cell differentiation by Notch | Q64379236 | ||
| Increased osteoclast development after estrogen loss: mediation by interleukin-6 | Q68188964 | ||
| Bone cell communication factors and Semaphorins | Q27023494 | ||
| Analyzing real-time PCR data by the comparative C(T) method | Q28131831 | ||
| Control of daughter cell fates during asymmetric division: interaction of Numb and Notch | Q28286748 | ||
| A Glanzmann's mutation in beta 3 integrin specifically impairs osteoclast function | Q28364534 | ||
| Biochemical and computational analysis of LNX1 interacting proteins | Q28477873 | ||
| The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis | Q28508398 | ||
| The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX | Q28509667 | ||
| Downregulation of small GTPase Rab7 impairs osteoclast polarization and bone resorption | Q28576916 | ||
| The Lnx family proteins function as molecular scaffolds for Numb family proteins | Q28589634 | ||
| LIS1 regulates osteoclast formation and function through its interactions with dynein/dynactin and Plekhm1 | Q28593263 | ||
| Regulation of osteoclast differentiation | Q28593319 | ||
| Osteoclast differentiation and activation | Q29547556 | ||
| The canonical Notch signaling pathway: unfolding the activation mechanism | Q29547725 | ||
| Genetic regulation of osteoclast development and function | Q29617421 | ||
| Osteoclast fusion and fission | Q30514009 | ||
| Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse | Q33646429 | ||
| Downregulation of Notch modulators, tetraspanin 5 and 10, inhibits osteoclastogenesis in vitro | Q34071113 | ||
| The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila | Q34145953 | ||
| Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells | Q34157287 | ||
| Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain | Q34189079 | ||
| Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase | Q34378600 | ||
| Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling | Q34391655 | ||
| Protein degradation: four E3s for the notch pathway | Q34511141 | ||
| The multiple functions of Numb | Q35014902 | ||
| Requirement for NF-kappaB in osteoclast and B-cell development | Q35199657 | ||
| Interaction of Notch signaling modulator Numb with α-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells | Q36006932 | ||
| TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. | Q36404187 | ||
| Osteoblast lineage-specific effects of notch activation in the skeleton | Q36542861 | ||
| Osteoporosis: now and the future | Q36564425 | ||
| Notch signaling at a glance | Q36903753 | ||
| Dimorphic effects of Notch signaling in bone homeostasis. | Q37165102 | ||
| Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption | Q37249047 | ||
| Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation | Q37339719 | ||
| Local communication on and within bone controls bone remodeling. | Q37433014 | ||
| Numb regulates post-endocytic trafficking and degradation of Notch1. | Q37446670 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 465-475 | |
| P577 | publication date | 2015-02-25 | |
| P1433 | published in | Calcified Tissue International | Q5018771 |
| P1476 | title | Ubiquitin E3 Ligase LNX2 is Critical for Osteoclastogenesis In Vitro by Regulating M-CSF/RANKL Signaling and Notch2. | |
| P478 | volume | 96 |
| Q64925962 | Deubiquitinating Enzymes and Bone Remodeling. |
| Q47936928 | Fullerenol nanoparticles suppress RANKL-induced osteoclastogenesis by inhibiting differentiation and maturation. |
| Q36833454 | Identification of a new locus and validation of previously reported loci showing differential methylation associated with smoking. The REGICOR study |
| Q37513913 | LIS1 Regulates Osteoclastogenesis through Modulation of M-SCF and RANKL Signaling Pathways and CDC42. |
| Q97884826 | LNX1/LNX2 proteins: functions in neuronal signalling and beyond |
| Q59130214 | NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts |
| Q36960089 | Notch Signaling and the Skeleton |
| Q36047882 | Notch signaling promotes osteoclast maturation and resorptive activity. |
| Q47186726 | Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase |
| Q37151513 | RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival |
| Q36544098 | Structural basis for the indispensable role of a unique zinc finger motif in LNX2 ubiquitination |
| Q89115516 | The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects |
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