Osteoblast lineage-specific effects of notch activation in the skeleton

scientific article published on 28 December 2012

Osteoblast lineage-specific effects of notch activation in the skeleton is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1210/EN.2012-1732
P932PMC publication ID3548181
P698PubMed publication ID23275471

P50authorErnesto CanalisQ56269284
Stefano ZanottiQ56269901
Kristen ParkerQ117248443
P2093author name stringJian Q Feng
Ernesto Canalis
P2860cites workThe novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formationQ24292169
Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexesQ24307538
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HERP, a new primary target of Notch regulated by ligand bindingQ24550855
Notch signaling controls multiple steps of pancreatic differentiationQ24569636
RANK is essential for osteoclast and lymph node developmentQ24598872
The amazing osteocyteQ24635849
Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1Q24653515
Localization of ADAM10 and Notch receptors in boneQ28140604
HES and HERP families: multiple effectors of the Notch signaling pathwayQ28205103
Matrix-embedded cells control osteoclast formationQ28247746
Evidence for osteocyte regulation of bone homeostasis through RANKL expressionQ28247757
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domainQ28273268
Direct regulation of intestinal fate by NotchQ28507015
HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segmentsQ28587806
Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the geneQ28776291
Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature CommitteeQ29616160
Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels.Q30531794
Notch and the skeletonQ33627230
RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal developmentQ33786247
Update in new anabolic therapies for osteoporosisQ33786824
Marrow stromal stem cellsQ33947769
Notch signaling: the core pathway and its posttranslational regulationQ34017623
Fine-tuning of the intracellular canonical Notch signaling pathway.Q34245052
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.Q34501252
Regulation of bone mass by Wnt signalingQ34576629
More complicated than it looks: assembly of Notch pathway transcription complexesQ34817647
Bone morphogenetic proteins, their antagonists, and the skeletonQ35109618
Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.Q35728669
Genetic mouse models for bone studies--strengths and limitationsQ35902980
Osteocyte RANKL: new insights into the control of bone remodelingQ36253514
Transgenic expression of COL1A1-chloramphenicol acetyltransferase fusion genes in bone: differential utilization of promoter elements in vivo and in cultured cellsQ36697983
Notch inhibits osteoblast differentiation and causes osteopeniaQ36796561
Notch signaling and its integration with other signaling mechanisms.Q36804582
Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration.Q36838533
Mechanisms of anabolic therapies for osteoporosisQ36924676
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
Dimorphic effects of Notch signaling in bone homeostasis.Q37165102
Identification of differentially expressed genes between osteoblasts and osteocytesQ37316190
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiationQ37339719
Guidelines for assessment of bone microstructure in rodents using micro-computed tomographyQ37763651
Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiationQ37958663
Conditional disruption of calcineurin B1 in osteoblasts increases bone formation and reduces bone resorption.Q38298134
Effect of primary and secondary structure of oligodeoxyribonucleotides on the fluorescent properties of conjugated dyesQ39600740
Multiplex quantitative PCR using self-quenched primers labeled with a single fluorophoreQ39600850
Different thermostabilities of FLP and Cre recombinases: implications for applied site-specific recombinationQ39717984
DMP1-targeted Cre expression in odontoblasts and osteocytesQ40154569
On Bone-Forming Cells and Blood Vessels in Bone DevelopmentQ41138377
Regulation of type I collagen gene expression in boneQ42472130
Upstream regulatory elements necessary for expression of the rat COL1A1 promoter in transgenic miceQ42495164
Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblastQ43434401
Cortisol regulates the expression of Notch in osteoblastsQ43956288
One year of transgenic overexpression of osteoprotegerin in rats suppressed bone resorption and increased vertebral bone volume, density, and strengthQ46171552
Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: effects of age and sex.Q48723022
Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors.Q50722204
Expression and activity of osteoblast-targeted Cre recombinase transgenes in murine skeletal tissues.Q50790300
NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.Q50878030
Age-related changes in trabecular architecture differ in female and male C57BL/6J mice.Q51009028
Directing the expression of a green fluorescent protein transgene in differentiated osteoblasts: comparison between rat type I collagen and rat osteocalcin promoters.Q52110147
Use of type I collagen green fluorescent protein transgenes to identify subpopulations of cells at different stages of the osteoblast lineage.Q52125683
Reciprocal temporospatial patterns of Msx2 and Osteocalcin gene expression during murine odontogenesis.Q52188708
Function of osteocytes in boneQ72809732
Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralizationQ74742272
Targeted ablation of osteocytes induces osteoporosis with defective mechanotransductionQ80432871
The fate of circulating osteoblastsQ81738834
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectosteoblastQ917177
P304page(s)623-634
P577publication date2012-12-28
P1433published inEndocrinologyQ3054009
P1476titleOsteoblast lineage-specific effects of notch activation in the skeleton
P478volume154

Reverse relations

cites work (P2860)
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Q37209043Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH.
Q34071113Downregulation of Notch modulators, tetraspanin 5 and 10, inhibits osteoclastogenesis in vitro
Q47963128Effects of Sex and Notch Signaling on the Osteocyte Cell Pool
Q37423382Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans
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Q88162688Glucocorticoids inhibit notch target gene expression in osteoblasts
Q47907947Hairy and Enhancer of Split-Related With YRPW Motif-Like (HeyL) Is Dispensable for Bone Remodeling in Mice
Q37048325Hairy and Enhancer of Split-related with YRPW motif (HEY)2 regulates bone remodeling in mice
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Q42682923Hajdu Cheney Syndrome; report of a novel NOTCH2 mutation and treatment with denosumab
Q34728226Hajdu-Cheney syndrome: a review
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Q37227350Interleukin 6 mediates selected effects of Notch in chondrocytes
Q33850283Intermittent activation of notch signaling promotes bone formation
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Q33835628Maintenance of Bone Homeostasis by DLL1-Mediated Notch Signaling
Q99234123Mechanisms of bone development and repair
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Q37675480Notch1 and Notch2 expression in osteoblast precursors regulates femoral microarchitecture
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Q35737544mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway

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