Canonical Notch activation in osteocytes causes osteopetrosis

scientific article

Canonical Notch activation in osteocytes causes osteopetrosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPENDO.00395.2015
P932PMC publication ID4719030
P698PubMed publication ID26578715

P50authorErnesto CanalisQ56269284
Stefano ZanottiQ56269901
Lauren SchillingQ117248445
P2093author name stringErnesto Canalis
David Bridgewater
P2860cites workStructural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexesQ24307538
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
HERP, a new primary target of Notch regulated by ligand bindingQ24550855
Notch signaling controls multiple steps of pancreatic differentiationQ24569636
RANK is essential for osteoclast and lymph node developmentQ24598872
Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1Q24653515
In vitro and in vivo approaches to study osteocyte biologyQ26858876
HES and HERP families: multiple effectors of the Notch signaling pathwayQ28205103
Matrix-embedded cells control osteoclast formationQ28247746
Evidence for osteocyte regulation of bone homeostasis through RANKL expressionQ28247757
Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling BoneQ28267634
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiationQ28505419
Direct regulation of intestinal fate by NotchQ28507015
The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesisQ28508398
HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segmentsQ28587806
Notch signaling in osteocytes differentially regulates cancellous and cortical bone remodelingQ28590415
Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the geneQ28776291
Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature CommitteeQ29616160
Dickkopf-1 is a member of a new family of secreted proteins and functions in head inductionQ29616164
Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in boneQ30619950
Notch and the skeletonQ33627230
RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal developmentQ33786247
Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in boneQ34188560
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.Q34501252
HES1 (Hairy and Enhancer of Split 1) Is a Determinant of Bone MassQ34509386
Reciprocal regulation of Notch and nuclear factor of activated T-cells (NFAT) c1 transactivation in osteoblastsQ34575649
More complicated than it looks: assembly of Notch pathway transcription complexesQ34817647
Osteosclerosis owing to Notch gain of function is solely Rbpj-dependentQ35078672
Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone developmentQ35768096
Notch signaling in skeletal health and diseaseQ35848797
Update on Wnt signaling in bone cell biology and bone disease.Q36083303
Bone quality--the material and structural basis of bone strength and fragilityQ36488553
Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9.Q36542533
Osteoblast lineage-specific effects of notch activation in the skeletonQ36542861
β-catenin promotes bone formation and suppresses bone resorption in postnatal growing miceQ36780867
Notch inhibits osteoblast differentiation and causes osteopeniaQ36796561
Standardized nomenclature, symbols, and units for bone histomorphometry: a 2012 update of the report of the ASBMR Histomorphometry Nomenclature CommitteeQ36901599
Mechanisms of anabolic therapies for osteoporosisQ36924676
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
Dimorphic effects of Notch signaling in bone homeostasis.Q37165102
The osteocyte: an endocrine cell ... and moreQ37203605
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiationQ37339719
Notch1 and Notch2 expression in osteoblast precursors regulates femoral microarchitectureQ37675480
Guidelines for assessment of bone microstructure in rodents using micro-computed tomographyQ37763651
Wnt signalling in osteoporosis: mechanisms and novel therapeutic approachesQ38128460
Effect of primary and secondary structure of oligodeoxyribonucleotides on the fluorescent properties of conjugated dyesQ39600740
Multiplex quantitative PCR using self-quenched primers labeled with a single fluorophoreQ39600850
Biphasic and dosage-dependent regulation of osteoclastogenesis by β-cateninQ39663212
Different thermostabilities of FLP and Cre recombinases: implications for applied site-specific recombinationQ39717984
Bone morphogenetic protein-2 enhances Wnt/beta-catenin signaling-induced osteoprotegerin expressionQ39890667
DMP1-targeted Cre expression in odontoblasts and osteocytesQ40154569
Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signalingQ40331060
Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerinQ42174982
One year of transgenic overexpression of osteoprotegerin in rats suppressed bone resorption and increased vertebral bone volume, density, and strengthQ46171552
NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.Q50878030
Age-related changes in trabecular architecture differ in female and male C57BL/6J mice.Q51009028
Muscle force regulates bone shaping for optimal load-bearing capacity during embryogenesis.Q51861192
Mechanotransduction and functional response of the skeleton to physical stress: the mechanisms and mechanics of bone adaptation.Q52231687
Role of the RAM domain and ankyrin repeats on notch signaling and activity in cells of osteoblastic lineage.Q53608998
Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decisionQ74211426
The bone remodeling compartment: a circulatory function for bone lining cellsQ74488805
Targeted ablation of osteocytes induces osteoporosis with defective mechanotransductionQ80432871
P433issue2
P304page(s)E171-82
P577publication date2015-11-17
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleCanonical Notch activation in osteocytes causes osteopetrosis
P478volume310

Reverse relations

cites work (P2860)
Q88162688Glucocorticoids inhibit notch target gene expression in osteoblasts
Q47907947Hairy and Enhancer of Split-Related With YRPW Motif-Like (HeyL) Is Dispensable for Bone Remodeling in Mice
Q36960089Notch Signaling and the Skeleton
Q89860460Notch Signaling in Skeletal Development, Homeostasis and Pathogenesis
Q49893022Notch expressed by osteocytes plays a critical role in mineralisation.
Q92177829Overexpression of Notch Signaling Induces Hyperosteogeny in Zebrafish
Q42511931Parathyroid hormone inhibits Notch signaling in osteoblasts and osteocytes
Q39287117TNF and Bone Remodeling
Q39107516The Role of the Osteocyte in Bone and Nonbone Disease

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