Differential regulation of specific genes in MCF-7 and the ICI 182780-resistant cell line MCF-7/182R-6.

scientific article published on February 1999

Differential regulation of specific genes in MCF-7 and the ICI 182780-resistant cell line MCF-7/182R-6. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.BJC.6690061
P932PMC publication ID2362436
P698PubMed publication ID10027303
P5875ResearchGate publication ID13262868

P2093author name stringB L Jensen
A E Lykkesfeldt
J Skouv
B K Lundholt
P2860cites workDifferential display of eukaryotic messenger RNA by means of the polymerase chain reactionQ28131789
The human estrogen receptor has two independent nonacidic transcriptional activation functionsQ29617089
Changes in estrogen receptor, progesterone receptor, and pS2 expression in tamoxifen-resistant human breast cancer.Q34300189
Oestrogen receptor: a stable phenotype in breast cancerQ36134377
Induction of estrogen independence of ZR-75-1 human breast cancer cells by epigenetic alterationsQ36677696
Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnoverQ37599824
Tamoxifen in advanced breast cancerQ39782157
36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein POQ40505449
Are breast tumours resistant to tamoxifen also resistant to pure antioestrogens?Q40797410
Resistance of human breast-cancer cells to the pure steroidal anti-estrogen ICI 182,780 is not associated with a general loss of estrogen-receptor expression or lack of estrogen responsivenessQ41083185
Response-specific antiestrogen resistance in a newly characterized MCF-7 human breast cancer cell line resulting from long-term exposure to trans-hydroxytamoxifenQ41160149
Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell linesQ41198739
Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cellsQ41291278
Human breast cancer cell lines resistant to pure anti-estrogens are sensitive to tamoxifen treatmentQ41345051
Differential expression of estrogen receptor mRNA splice variants in the tamoxifen resistant human breast cancer cell line, MCF-7/TAMR-1 compared to the parental MCF-7 cell lineQ41354892
Mechanisms of tamoxifen resistance in the treatment of advanced breast cancerQ41463841
Altered expression of estrogen-regulated genes in a tamoxifen-resistant and ICI 164,384 and ICI 182,780 sensitive human breast cancer cell line, MCF-7/TAMR-1.Q41480629
The mechanism of ICI 164,384 antiestrogenicity involves rapid loss of estrogen receptor in uterine tissueQ41661309
Expression of estrogen receptor and its messenger ribonucleic acid in the MCF-7 cell line: multiparametric analysis of its processing and regulation by estrogenQ41714899
Hormonal regulation of estrogen receptor messenger ribonucleic acid in T47Dco and MCF-7 breast cancer cellsQ42505128
Effect of estrogen and antiestrogen on the human breast cancer cell line MCF-7 adapted to growth at low serum concentrationQ42822693
A potent specific pure antiestrogen with clinical potentialQ46965638
Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer.Q54172521
Antiestrogen resistance: mechanisms by which breast cancer cells undermine the effectiveness of endocrine therapy.Q54286503
Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancerQ59289357
Nuclear mechanisms of estrogen action. Effects of estradiol and anti-estrogens on estrogen receptors and nuclear receptor processingQ67404696
Regulation of the estrogen receptor in MCF-7 cells by estradiolQ68015751
Estrogenic and antiestrogenic regulation of the half-life of covalently labeled estrogen receptor in MCF-7 breast cancer cellsQ71114385
The value of estrogen and progesterone receptors in the treatment of breast cancerQ71432010
Estradiol-induced down-regulation of estrogen receptor. Effect of various modulators of protein synthesis and expressionQ72326474
Selective inhibition of estrogen-regulated gene expression in vivo by the pure antiestrogen ICI 182,780Q73470551
Acquired estrogen independence and antiestrogen resistance in breast cancer: estrogen receptor driven phenotypes?Q81066714
P4510describes a project that usesMCF-7/182R-6Q54904343
P433issue3-4
P407language of work or nameEnglishQ1860
P921main subjectcell lineQ21014462
P304page(s)386-392
P577publication date1999-02-01
P1433published inBritish Journal of CancerQ326309
P1476titleDifferential regulation of specific genes in MCF-7 and the ICI 182780-resistant cell line MCF-7/182R-6.
P478volume79

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cites work (P2860)
Q37038692A candidate molecular signature associated with tamoxifen failure in primary breast cancer
Q37393002Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant
Q28359567Anti-oestrogen resistant human breast cancer cell lines are more sensitive towards treatment with the vitamin D analogue EB1089 than parent MCF-7 cells
Q40823033Demonstration of estrogen receptors and of estrogen responsiveness in the HKT-1097 cell line derived from diethylstilbestrol-induced kidney tumors
Q36620883Development and characterization of a tamoxifen-resistant breast carcinoma xenograft
Q64120894Differential microRNA expression profiles determined by next-generation sequencing in three fulvestrant-resistant human breast cancer cell lines
Q40649819Effect of antiestrogens and aromatase inhibitor on basal growth of the human breast cancer cell line MCF-7 in serum-free medium
Q39756962Effects of nutrition relevant mixtures of phytoestrogens on steroidogenesis, aromatase, estrogen, and androgen activity
Q40541435Estrogen responsiveness of IBEP-2, a new human cell line derived from breast carcinoma
Q43704085Identification of two estrogen regulated genes associated with growth regulation of human breast cancer.
Q54028727Increased expression of cytochrome p450 1A1 and 1B1 genes in anti-estrogen-resistant human breast cancer cell lines.
Q43678719Insulin-like growth factor receptor levels are regulated by cell density and by long term estrogen deprivation in MCF7 human breast cancer cells
Q35168124New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane
Q43641338Novel cell lines established from a human myxoid malignant fibrous histiocytoma arising in the uterus
Q30441001Pathways to tamoxifen resistance
Q37169153Prostaglandin F2alpha elevates blood pressure and promotes atherosclerosis.
Q37066053Tamoxifen resistance and epigenetic modifications in breast cancer cell lines
Q31875534The control of progesterone receptor expression in MCF-7 breast cancer cells: effects of estradiol and sex hormone-binding globulin (SHBG).
Q37328397The role of amphiregulin in exemestane-resistant breast cancer cells: evidence of an autocrine loop

Q54904343MCF-7/182R-6described by sourceP1343

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