p53 status of newly established acute myeloid leukaemia cell lines

scientific article published on February 1999

p53 status of newly established acute myeloid leukaemia cell lines is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1039381316
P356DOI10.1038/SJ.BJC.6690064
P932PMC publication ID2362446
P698PubMed publication ID10027306
P5875ResearchGate publication ID13262871

P2093author name stringVähäkangas K
Savolainen ER
Koistinen P
Castren K
Säily M
Zheng A
P2860cites workThe gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13)Q24633330
p53, the cellular gatekeeper for growth and divisionQ27860990
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivationQ28280958
Proposals for the Classification of the Acute Leukaemias French-American-British (FAB) Co-operative GroupQ28296408
p53-dependent apoptosis modulates the cytotoxicity of anticancer agentsQ29615031
Participation of p53 protein in the cellular response to DNA damageQ29618319
p53: puzzle and paradigmQ29618407
Localization of gene for human p53 tumour antigen to band 17p13.Q34179671
Structure and function of the p53 tumor suppressor gene: clues for rational cancer therapeutic strategiesQ34400583
Database of p53 gene somatic mutations in human tumors and cell linesQ34868968
p53 immunohistochemistry in transitional cell carcinoma and dysplasia of the urinary bladder correlates with disease progressionQ35977771
Expression of different conformations of p53 in the blast cells of acute myeloblastic leukaemia is related to in vitro growth characteristicsQ35977787
Altered conformation of the p53 protein in myeloid leukemia cells and mitogen-stimulated normal blood cellsQ36322555
Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damageQ36557538
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiationQ36564865
Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stabilityQ36564973
Accumulation of p53 in a mutant cell line defective in the ubiquitin pathwayQ36648425
Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agentsQ38319213
Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cellsQ40237209
A transcriptionally active DNA-binding site for human p53 protein complexesQ40655196
Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesisQ40694250
Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax:Bcl-2 ratio.Q41205685
How phosphorylation regulates the activity of p53.Q41206472
Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant formQ41210647
p53 protein expression is correlated with benzo[a]pyrene-DNA adducts in carcinoma cell linesQ41305946
Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 geneQ41470010
Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cellsQ41483255
Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?Q41513765
Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agentsQ41575832
Constitutive expression of p53 protein in enriched normal human marrow blast cell populationsQ41628815
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replicationQ44703400
Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancerQ45066172
High incidence of potential p53 inactivation in poor outcome childhood acute lymphoblastic leukemia at diagnosisQ47630133
Absence of p53 mutations in benign and pre-malignant male genital lesions with over-expressed p53 proteinQ47751193
Mechanisms of p53 alteration in acute leukemiasQ52507505
Single-strand conformation polymorphism analysis to detect p53 mutations: characterization and development of controls.Q53438154
Mutations of p53 and ras genes in radon-associated lung cancer from uranium miners.Q53491590
Mutations of the P53 gene in acute myeloid leukaemiaQ68077839
Frequent mutations in the p53 gene in human myeloid leukemia cell linesQ68104797
Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformationQ70168032
In vivo ubiquitination and proteasome-mediated degradation of p53(1)Q71129152
A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiationQ71169980
Disappointments in treating acute leukemia in the elderlyQ71694659
p53-dependent apoptosis suppresses tumor growth and progression in vivoQ72149266
The involvement of "tumor suppressor" p53 in normal and chronic myelogenous leukemia hemopoiesisQ72692111
p53 in tumour pathology: can we trust immunohistochemistry?--Revisited!Q72730267
Forms and functions of p53Q72776249
Mutations of the p53 gene do not occur in testis cancerQ72851846
Inhibition of the growth of WI-38 fibroblasts by benzyloxycarbonyl-Leu-Leu-Tyr diazomethyl ketone: evidence that cleavage of p53 by a calpain-like protease is necessary for G1 to S-phase transitionQ73034002
P4510describes a project that usesOU-AML-1Q54936738
OU-AML-2Q54936739
OU-AML-3Q54936740
OU-AML-4Q54936741
OU-AML-5Q54936744
OU-AML-6Q54936745
OU-AML-7Q54936746
OU-AML-8Q54936748
P433issue3-4
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
cell lineQ21014462
P304page(s)407-415
P577publication date1999-02-01
P1433published inBritish Journal of CancerQ326309
P1476titlep53 status of newly established acute myeloid leukaemia cell lines
P478volume79

Reverse relations

described by source (P1343)
Q54936738OU-AML-1
Q54936739OU-AML-2
Q54936740OU-AML-3
Q54936741OU-AML-4
Q54936744OU-AML-5
Q54936745OU-AML-6
Q54936746OU-AML-7
Q54936748OU-AML-8

cites work (P2860)
Q40955900An association between mitochondrial function and all-trans retinoic acid-induced apoptosis in acute myeloblastic leukaemia cells
Q29303646False leukemia–lymphoma cell lines: an update on over 500 cell lines
Q27021173High-dimensional single-cell cancer biology
Q46307051Mapping normal and cancer cell signalling networks: towards single-cell proteomics
Q40715498Superior effect of 9-cis retinoic acid (RA) compared with all-trans RA and 13-cis RA on the inhibition of clonogenic cell growth and the induction of apoptosis in OCI/AML-2 subclones: is the p53 pathway involved?
Q26766341Targeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer Therapy
Q40771798p53 and redox state in etoposide-induced acute myeloblastic leukemia cell death

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