Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway

scientific article published on March 1994

Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.14.3.1997
P932PMC publication ID358559
P698PubMed publication ID8114731

P2093author name stringH L Ozer
K K Jha
J J Dermody
D R Chowdary
P2860cites workWild-type p53 binds to the TATA-binding protein and represses transcriptionQ24300991
A new technique for the assay of infectivity of human adenovirus 5 DNAQ27860797
UBA 1: an essential yeast gene encoding ubiquitin-activating enzymeQ27931184
The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzymeQ27933363
The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymesQ27935511
Cyclin is degraded by the ubiquitin pathwayQ28131704
Amplification of a gene encoding a p53-associated protein in human sarcomasQ28270924
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivationQ28280958
Identification of p53 as a sequence-specific DNA-binding proteinQ28282745
Amino acid sequences common to rapidly degraded proteins: the PEST hypothesisQ29547538
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumoursQ29547697
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53Q29547773
Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoterQ29614259
The ubiquitin system for protein degradationQ29614385
Suppression of human colorectal carcinoma cell growth by wild-type p53Q29618318
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasmsQ29618586
Wild-type p53 can inhibit oncogene-mediated focus formationQ30450825
Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1.Q33513306
Molecular cloning, primary structure and expression of the human X linked A1S9 gene cDNA which complements the ts A1S9 mouse L cell defect in DNA replicationQ33921464
Enhanced binding of a 95 kDa protein to p53 in cells undergoing p53-mediated growth arrestQ33937821
Transformation of mammalian cells with genes from procaryotes and eucaryotesQ34030262
Monoclonal antibodies specific for simian virus 40 tumor antigensQ34249232
The p53 proto-oncogene can act as a suppressor of transformationQ34440370
Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferaseQ35340408
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cellsQ35476763
p53 function and dysfunctionQ35721291
Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell lineQ35926080
Retinoblastoma protein and simian virus 40-dependent immortalization of human fibroblastsQ36692841
Binding of p53 and p105-RB is not sufficient for oncogenic transformation by a hybrid polyomavirus-simian virus 40 large T antigenQ36793131
The ability of large T antigen to complex with p53 is necessary for the increased life span and partial transformation of human cells by simian virus 40.Q36827839
The ability of simian virus 40 large T antigen to immortalize primary mouse embryo fibroblasts cosegregates with its ability to bind to p53.Q36828715
Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell linesQ36919740
Energy Requirement for Degradation of Tumor-Associated Protein p53Q36941962
Characterization of a ts mutant of BALB/3T3 cells and correction of the defect by in vitro addition of extracts from wild-type cellsQ36947586
Post-Translational Regulation of the 54K Cellular Tumor Antigen in Normal and Transformed CellsQ36966578
Degradation of nuclear oncoproteins by the ubiquitin system in vitroQ37361143
p53 mutations: gains or losses?Q37669027
The p53 tumour suppressor geneQ37751892
Regulation of the specific DNA binding function of p53Q38324290
Temperature-sensitive mutants of Balb/3T3 cells: Description of a mutant affected in cellular and polyoma virus DNA synthesisQ40006849
Monoclonal antibody analysis of p53 expression in normal and transformed cellsQ40127251
A transcriptionally active DNA-binding site for human p53 protein complexesQ40655196
Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant formQ41210647
Temperature-sensitive mutants of BALB/3T3 cells. III. Hybrids between ts2 and other mouse mutant cells affected in DNA synthesis and correction of ts2 defect by human X chromosomeQ42828142
Specific interaction between the p53 cellular tumour antigen and major heat shock proteinsQ43512047
Level of ubiquitinated histone H2B in chromatin is coupled to ongoing transcriptionQ44511165
Restriction of human adenovirus replication in Chinese hamster cell lines and their hybrids with human cellsQ44672534
A site-directed approach for constructing temperature-sensitive ubiquitin-conjugating enzymes reveals a cell cycle function and growth function for RAD6Q44687600
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replicationQ44703400
Regulation of the level of the oncoprotein p53 in non-transformed and transformed cells.Q44769248
Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.Q53505779
Mutant p53 proteins bind hsp 72/73 cellular heat shock-related proteins in SV40-transformed monkey cells.Q53529837
Temperature-dependent switching between "wild-type" and "mutant" forms of p53-Val135.Q53965077
Construction of a fusion gene that confers resistance against hygromycin B to mammalian cells in culture.Q54451283
Regulation of the human hsp70 promoter by p53Q64377885
Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cellsQ64381309
Requirements for immortalization of primary mouse embryo fibroblasts probed with mutants bearing deletions in the 3' end of SV40 gene AQ69815443
Differential replication of SV40 and polyoma DNAs in Chinese hamster ovary cellsQ70099048
P4510describes a project that usesBALB/3T3 clone A31 ts20Q54606748
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcell lineQ21014462
P304page(s)1997-2003
P577publication date1994-03-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleAccumulation of p53 in a mutant cell line defective in the ubiquitin pathway
P478volume14

Reverse relations

described by source (P1343)
Q54606748BALB/3T3 clone A31 ts20
Q111732953BALB/3T3 clone A31 ts22

cites work (P2860)
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