| scholarly article | Q13442814 |
| P50 | author | David P. Lane | Q909289 |
| P2093 | author name string | S Laín | |
| L F Stevenson | |||
| C F Cheok | |||
| S Menéndez | |||
| S Camus | |||
| P2860 | cites work | Intracellularly inducible, ubiquitin hydrolase-insensitive tandem ubiquitins inhibit the 26S proteasome activity and cell division | Q47294157 |
| Ubiquitin, E6-AP, and their role in p53 inactivation | Q47739961 | ||
| Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin | Q48151618 | ||
| Involvement of the 20S proteasome in the degradation of ornithine decarboxylase | Q70669683 | ||
| Sensitivity of p53 lysine mutants to ubiquitin-directed degradation targeted by human papillomavirus E6 | Q70995998 | ||
| p53 Stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products | Q74183048 | ||
| Binding of human papillomavirus 16 E6 to p53 and E6AP is impaired by monoclonal antibodies directed against the second zinc-binding domain of E6 | Q81562784 | ||
| Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis | Q82684619 | ||
| Massively parallel sequencing analysis of 68 gastric-type cervical adenocarcinomas reveals mutations in cell cycle-related genes and potentially targetable mutations | Q104471902 | ||
| Reconstitution of p53-ubiquitinylation reactions from purified components: the role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP) | Q24315626 | ||
| Inhibition of p53 DNA binding by human papillomavirus E6 proteins | Q24317013 | ||
| The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 | Q24317677 | ||
| Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53 | Q24321129 | ||
| Mdm2 promotes the rapid degradation of p53 | Q24322597 | ||
| Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 | Q24328775 | ||
| The global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase | Q24521626 | ||
| Involvement of the DNA repair protein hHR23 in p53 degradation | Q24633456 | ||
| Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis | Q28143403 | ||
| The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 | Q29547773 | ||
| The p53 pathway: positive and negative feedback loops | Q29617535 | ||
| Antizyme, a mediator of ubiquitin-independent proteasomal degradation | Q30168296 | ||
| Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells | Q33649218 | ||
| Regulation of Mdm2-directed degradation by the C terminus of p53. | Q33779929 | ||
| Growth suppression induced by downregulation of E6-AP expression in human papillomavirus-positive cancer cell lines depends on p53 | Q33883959 | ||
| Involvement of nuclear export in human papillomavirus type 18 E6-mediated ubiquitination and degradation of p53. | Q33883972 | ||
| The unfolding of substrates and ubiquitin-independent protein degradation by proteasomes | Q34214130 | ||
| Proteasome-dependent, ubiquitin-independent degradation of the Rb family of tumor suppressors by the human cytomegalovirus pp71 protein | Q34868376 | ||
| Mutational analysis of human papillomavirus type 16 E6 demonstrates that p53 degradation is necessary for immortalization of mammary epithelial cells | Q35854157 | ||
| Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway | Q36648425 | ||
| Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. | Q36660357 | ||
| Regulation of the specific DNA binding function of p53 | Q38324290 | ||
| High-risk human papillomavirus E6 protein has two distinct binding sites within p53, of which only one determines degradation. | Q39875158 | ||
| The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest. | Q40041446 | ||
| MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation | Q40323831 | ||
| MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein. | Q40342115 | ||
| Cell-free assay for ubiquitin-independent proteasomal protein degradation | Q40416982 | ||
| Differences in the ubiquitination of p53 by Mdm2 and the HPV protein E6. | Q40670809 | ||
| Multiple lysine mutations in the C-terminus of p53 make it resistant to degradation mediated by MDM2 but not by human papillomavirus E6 and induce growth inhibition in MDM2-overexpressing cells | Q40736222 | ||
| Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo. | Q40783221 | ||
| Molecular characterization of the thermosensitive E1 ubiquitin-activating enzyme cell mutant A31N-ts20. Requirements upon different levels of E1 for the ubiquitination/degradation of the various protein substrates in vivo | Q40874935 | ||
| Comparison of human papillomavirus type 18 (HPV-18) E6-mediated degradation of p53 in vitro and in vivo reveals significant differences based on p53 structure and cell type but little difference with respect to mutants of HPV-18 E6. | Q41014430 | ||
| Role of N-terminal residues in the ubiquitin-independent degradation of human thymidylate synthase | Q41818827 | ||
| Degradation of ornithine decarboxylase in mammalian cells is ATP dependent but ubiquitin independent | Q41945118 | ||
| alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome | Q43816254 | ||
| DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53. | Q44165063 | ||
| Identification of a region of p53 that confers lability | Q44468579 | ||
| Proteasomal degradation of RPN4 via two distinct mechanisms, ubiquitin-dependent and -independent | Q44848229 | ||
| N-acetylation and ubiquitin-independent proteasomal degradation of p21(Cip1). | Q45169911 | ||
| Probing the ubiquitin/proteasome system with ornithine decarboxylase, a ubiquitin-independent substrate | Q46301135 | ||
| Degradation of HMG-CoA reductase in rat liver is cholesterol and ubiquitin independent | Q46512348 | ||
| The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction | Q24292709 | ||
| Modulation of the chymotrypsin-like activity of the 20S proteasome by intracellular redox status: effects of glutathione peroxidase-1 overexpression and antioxidant drugs | Q24301968 | ||
| The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome | Q24302180 | ||
| Regulation of human p53 activity and cell localization by alternative splicing | Q24302205 | ||
| P433 | issue | 28 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4059-4070 | |
| P577 | publication date | 2007-01-15 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Ubiquitin-independent degradation of p53 mediated by high-risk human papillomavirus protein E6 | |
| P478 | volume | 26 |
| Q34509620 | A Small Ribosomal Subunit (SSU) Processome Component, the Human U3 Protein 14A (hUTP14A) Binds p53 and Promotes p53 Degradation |
| Q33800021 | Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6. |
| Q38961177 | BAG3 down-modulation sensitizes HPV18(+) HeLa cells to PEITC-induced apoptosis and restores p53. |
| Q41913902 | Binding of human papillomavirus type 16 E6 to E6AP is not required for activation of hTERT |
| Q34068211 | Cdk5 phosphorylates non-genotoxically overexpressed p53 following inhibition of PP2A to induce cell cycle arrest/apoptosis and inhibits tumor progression |
| Q40823203 | Clinical Significance of p53 and p16(ink4a) Status in a Contemporary North American Penile Carcinoma Cohort |
| Q92502624 | Co-expression of MDM2 and CDK4 in transformed human mesenchymal stem cells causes high-grade sarcoma with a dedifferentiated liposarcoma-like morphology |
| Q39640839 | Comparison of p53 and the PDZ domain containing protein MAGI-3 regulation by the E6 protein from high-risk human papillomaviruses |
| Q24308725 | Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling |
| Q33925875 | E6-associated protein is required for human papillomavirus type 16 E6 to cause cervical cancer in mice |
| Q40068344 | HPV E6 degradation of p53 and PDZ containing substrates in an E6AP null background |
| Q35012060 | HPV E6 proteins target Ubc9, the SUMO conjugating enzyme |
| Q39706027 | Hdm2 negatively regulates telomerase activity by functioning as an E3 ligase of hTERT. |
| Q35772958 | Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells. |
| Q37500155 | Interaction between viral proteins and hosts and its disturbance in the cellular responses to ionising radiation |
| Q35685208 | Intracellular Analysis of the Interaction between the Human Papillomavirus Type 16 E6 Oncoprotein and Inhibitory Peptides |
| Q37327240 | Manipulation of the ubiquitin-proteasome pathway by small DNA tumor viruses |
| Q36805303 | Molecular and genetic pathways in penile cancer |
| Q37189400 | Molecular prognostic factors in penile cancer |
| Q48215735 | NDRG2 contributes to cisplatin sensitivity through modulation of BAK-to-Mcl-1 ratio. |
| Q30421662 | Peptide interactions stabilize and restructure human papillomavirus type 16 E6 to interact with p53 |
| Q42707106 | Regulation of the human papillomavirus type 18 E6/E6AP ubiquitin ligase complex by the HECT domain-containing protein EDD. |
| Q27678346 | Solution Structure Analysis of the HPV16 E6 Oncoprotein Reveals a Self-Association Mechanism Required for E6-Mediated Degradation of p53 |
| Q27677967 | Structural Insights into a Wildtype Domain of the Oncoprotein E6 and Its Interaction with a PDZ Domain |
| Q42680947 | Susceptibility of p53 unstructured N terminus to 20 S proteasomal degradation programs the stress response. |
| Q35949401 | The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription. |
| Q39716120 | The immortalizing and transforming ability of two common human papillomavirus 16 E6 variants with different prevalences in cervical cancer |
| Q39189709 | The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover. |
| Q39367419 | The p53 isoforms are differentially modified by Mdm2. |
| Q84450757 | The stability of the human papillomavirus E6 oncoprotein is E6AP dependent |
| Q39831551 | Thyroid hormones reverse the UV-induced repression of APP in neuroblastoma cells. |
| Q96127450 | Two-Step Mechanism of Cyclin B Degradation Initiated by Proteolytic Cleavage with the 26 S Proteasome in Fish |
| Q53467454 | Ubiquitin over-expression promotes E6AP autodegradation and reactivation of the p53/MDM2 pathway in HeLa cells. |
| Q37531920 | Ubiquitin-independent p53 proteasomal degradation. |
| Q35354212 | Ubiquitin-independent proteasomal degradation during oncogenic viral infections |
| Q38229325 | Ubiquitination involved enzymes and cancer |
| Q37464765 | Viral avoidance and exploitation of the ubiquitin system. |
| Q37944142 | Virus manipulation of cell cycle. |
| Q35665960 | p53 degradation activity, expression, and subcellular localization of E6 proteins from 29 human papillomavirus genotypes |
Search more.