| scholarly article | Q13442814 |
| P50 | author | Maureen Murphy | Q15845077 |
| P2093 | author name string | D L George | |
| W H Hoffman | |||
| J T Zilfou | |||
| M Sank | |||
| P2860 | cites work | Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53 | Q22009955 |
| Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein | Q22010970 | ||
| Identification of a novel p53 functional domain that is necessary for efficient growth suppression | Q24311276 | ||
| Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain | Q24314763 | ||
| Mdm2 promotes the rapid degradation of p53 | Q24322597 | ||
| The MDM2 RING-finger domain is required to promote p53 nuclear export | Q45301160 | ||
| Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. | Q48354837 | ||
| An engineered four-stranded coiled coil substitutes for the tetramerization domain of wild-type p53 and alleviates transdominant inhibition by tumor-derived p53 mutants | Q70866376 | ||
| In vivo ubiquitination and proteasome-mediated degradation of p53(1) | Q71129152 | ||
| p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells | Q71618789 | ||
| The domain of p53 required for binding HPV 16 E6 is separable from the degradation domain | Q72520479 | ||
| RB regulates the stability and the apoptotic function of p53 via MDM2 | Q74607074 | ||
| Signaling to p53: breaking the MDM2-p53 circuit | Q77430977 | ||
| Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity | Q77733994 | ||
| Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 | Q24328775 | ||
| The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression | Q24533291 | ||
| Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53 | Q24672736 | ||
| Regulation of p53 stability by Mdm2 | Q27860744 | ||
| p53, the cellular gatekeeper for growth and division | Q27860990 | ||
| p300/MDM2 complexes participate in MDM2-mediated p53 degradation | Q28288274 | ||
| Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53. | Q28590239 | ||
| Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage | Q28609754 | ||
| Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2 | Q28609844 | ||
| p53: puzzle and paradigm | Q29618407 | ||
| Histone deacetylases: transcriptional repression with SINers and NuRDs | Q33632987 | ||
| Regulation of the p53 tumor suppressor protein | Q33792315 | ||
| Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. | Q33888123 | ||
| The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. | Q33889383 | ||
| Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc. | Q33890400 | ||
| A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking | Q33890625 | ||
| Excess beta-catenin promotes accumulation of transcriptionally active p53. | Q33891005 | ||
| Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. | Q35207550 | ||
| JNK targets p53 ubiquitination and degradation in nonstressed cells | Q35208651 | ||
| Synergistic activation of p53 by inhibition of MDM2 expression and DNA damage | Q35671727 | ||
| Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2 | Q36174385 | ||
| The ubiquitin-proteasome pathway in cancer | Q36295120 | ||
| Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability | Q36564973 | ||
| Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway | Q36648425 | ||
| Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage | Q36777971 | ||
| Identification of a sequence element from p53 that signals for Mdm2-targeted degradation | Q39450966 | ||
| Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6 | Q39576878 | ||
| Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction. | Q40918850 | ||
| DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization | Q40960688 | ||
| p53 in growth control and neoplasia | Q41009705 | ||
| The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells. | Q41052233 | ||
| Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo. | Q41063629 | ||
| The polyproline region of p53 is required to activate apoptosis but not growth arrest. | Q41093439 | ||
| Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cells | Q41128329 | ||
| Wild-type p53 negatively regulates the expression of a microtubule-associated protein | Q41148864 | ||
| The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway | Q41148875 | ||
| Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation | Q41712972 | ||
| Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines | Q41733469 | ||
| Characterization of sequence elements involved in p53 stability regulation reveals cell type dependence for p53 degradation | Q42822984 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| P304 | page(s) | 3974-3985 | |
| P577 | publication date | 2001-06-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation | |
| P478 | volume | 21 |
| Q42812083 | A major functional difference between the mouse and human ARF tumor suppressor proteins |
| Q40413949 | Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination |
| Q34605518 | Activation of the p53 tumor suppressor protein |
| Q60614674 | An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo |
| Q24622900 | Biological influence of Hakai in cancer: a 10-year review |
| Q40054485 | CIITA mediates interferon-gamma repression of collagen transcription through phosphorylation-dependent interactions with co-repressor molecules. |
| Q39814358 | Cabin1 restrains p53 activity on chromatin. |
| Q30401329 | Cancer susceptibility polymorphism of p53 at codon 72 affects phosphorylation and degradation of p53 protein |
| Q42611068 | Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation |
| Q24311663 | Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA binding |
| Q35116663 | Decision making by p53: life, death and cancer |
| Q30566367 | Effects of prostaglandin E2 on p53 mRNA transcription and p53 mutagenesis during T-cell-independent human B-cell clonal expansion |
| Q92259153 | Focus-ING on DNA Integrity: Implication of ING Proteins in Cell Cycle Regulation and DNA Repair Modulation |
| Q24315091 | HOXA5-twist interaction alters p53 homeostasis in breast cancer cells |
| Q33732110 | Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters |
| Q47129006 | Identification and characterization of a metastatic suppressor BRMS1L as a target gene of p53. |
| Q37583477 | Identification of a negative regulatory element in the Epstein-Barr virus Zta transactivation domain that is regulated by the cell cycle control factors c-Myc and E2F1. |
| Q28589914 | Identification of novel co-repressor molecules for Interferon Regulatory Factor-2 |
| Q39686347 | Inhibition of polyomavirus ori-dependent DNA replication by mSin3B |
| Q34979737 | KAP1 promotes proliferation and metastatic progression of breast cancer cells |
| Q36446127 | Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence |
| Q29547663 | Live or let die: the cell's response to p53 |
| Q45246957 | Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival. |
| Q36436702 | Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo |
| Q24297694 | NIR is a novel INHAT repressor that modulates the transcriptional activity of p53. |
| Q46966336 | NM23-H1 tumor suppressor and its interacting partner STRAP activate p53 function |
| Q46242652 | PEPD is a pivotal regulator of p53 tumor suppressor |
| Q34173442 | Posttranscriptional and posttranslational regulation of C/EBP delta in G0 growth-arrested mammary epithelial cells |
| Q36449409 | Radioprobing the conformation of DNA in a p53-DNA complex |
| Q37636014 | Regulation of p53--insights into a complex process |
| Q35225077 | Resveratrol, through NF-Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor alpha gene expression via p38MAPK/CK2 signaling in human breast cancer cells |
| Q35964130 | Sin3: a flexible regulator of global gene expression and genome stability. |
| Q36436693 | Some p53-binding proteins that can function as arbiters of life and death. |
| Q36185135 | Stress-mediated Sin3B activation leads to negative regulation of subset of p53 target genes. |
| Q30375203 | Structure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation. |
| Q24563144 | Suppression of tumorigenesis by the p53 target PUMA |
| Q24556628 | The C terminus of p53 family proteins is a cell fate determinant |
| Q24292959 | The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription |
| Q31023819 | The Proline Repeat Domain of p53 Binds Directly to the Transcriptional Coactivator p300 and Allosterically Controls DNA-Dependent Acetylation of p53 |
| Q34441108 | The SIN3/RPD3 deacetylase complex is essential for G(2) phase cell cycle progression and regulation of SMRTER corepressor levels |
| Q40624316 | The co-repressor hairless protects RORalpha orphan nuclear receptor from proteasome-mediated degradation |
| Q40672888 | The codon 72 polymorphic variants of p53 have markedly different apoptotic potential |
| Q35544219 | The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1. |
| Q34487385 | The evolution of diverse biological responses to DNA damage: insights from yeast and p53. |
| Q42176327 | The mSin3A chromatin-modifying complex is essential for embryogenesis and T-cell development |
| Q47870575 | The proline rich domain of p53 is dispensable for MGMT-dependent DNA repair and cell survival following alkylation damage |
| Q33707631 | Transcription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene |
| Q37777267 | Transcriptional regulation by p53. |
| Q36436698 | Transcriptional regulation by p53: one protein, many possibilities |
| Q44522476 | Transcriptional regulation of mitotic checkpoint gene MAD1 by p53. |
| Q39984512 | Transcriptional repression by p53 promotes a Bcl-2-insensitive and mitochondria-independent pathway of apoptosis |
| Q47774820 | Transcriptional repression of Aurora-A gene by wild-type p53 through directly binding to its promoter with histone deacetylase 1 and mSin3a. |
| Q50335767 | Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. |
| Q51901182 | Transformation-Related Protein 53 Expression in the Early Mouse Embryo Compromises Preimplantation Embryonic Development by Preventing the Formation of a Proliferating Inner Cell Mass1 |
| Q37412688 | Tumor suppressive functions of p53 |
| Q40317250 | Tumor suppressor p53 regulates heparanase gene expression |
| Q34058409 | Tumor suppressor protein p53 recruits human Sin3B/HDAC1 complex for down-regulation of its target promoters in response to genotoxic stress |
| Q40568020 | Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes. |
| Q24537696 | Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex |
| Q37531920 | Ubiquitin-independent p53 proteasomal degradation. |
| Q35089377 | Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation |
| Q24301669 | Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor |
| Q28512979 | mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival |
| Q40647697 | p21/CDKN1A mediates negative regulation of transcription by p53. |
| Q36430165 | p53 and disease: when the guardian angel fails |
| Q39371481 | p53 in human embryonal carcinoma: identification of a transferable, transcriptional repression domain in the N-terminal region of p53. |
| Q57929625 | p53 latency – out of the blind alley |
| Q36567469 | p53 sumoylation: mechanistic insights from reconstitution studies |
| Q42660335 | p53 targets chromatin structure alteration to repress alpha-fetoprotein gene expression |
| Q40515208 | p53-dependent down-regulation of telomerase is mediated by p21waf1. |
| Q36846083 | p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo |
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