| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2008PNAS..105.1215J |
| P356 | DOI | 10.1073/PNAS.0706764105 |
| P932 | PMC publication ID | 2234118 |
| P698 | PubMed publication ID | 18216268 |
| P5875 | ResearchGate publication ID | 5635995 |
| P2093 | author name string | Thomas M Johnson | |
| Laura D Attardi | |||
| Navneeta Pathak | |||
| Michelle R Marques | |||
| Kristin Meade | |||
| P2860 | cites work | A novel cofactor for p300 that regulates the p53 response | Q22010639 |
| The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation | Q24291244 | ||
| ASPP proteins specifically stimulate the apoptotic function of p53 | Q24291844 | ||
| p53 has a direct apoptogenic role at the mitochondria | Q24298888 | ||
| Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis | Q24307994 | ||
| Mdm2 promotes the rapid degradation of p53 | Q24322597 | ||
| Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 | ||
| A biomarker that identifies senescent human cells in culture and in aging skin in vivo | Q24562644 | ||
| Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis | Q24681977 | ||
| Regulation of p53 stability by Mdm2 | Q27860744 | ||
| Surfing the p53 network | Q28032484 | ||
| Definition of a p53 transactivation function-deficient mutant and characterization of two independent p53 transactivation subdomains | Q28143960 | ||
| The complexity of p53 modulation: emerging patterns from divergent signals | Q28284854 | ||
| The interaction of p53 with replication protein A mediates suppression of homologous recombination | Q28288360 | ||
| p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60 | Q28304820 | ||
| Bax suppresses tumorigenesis and stimulates apoptosis in vivo | Q28506493 | ||
| PML is a direct p53 target that modulates p53 effector functions | Q28586691 | ||
| Live or let die: the cell's response to p53 | Q29547663 | ||
| Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53 | Q29617850 | ||
| Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A | Q30446685 | ||
| Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. | Q34011633 | ||
| Dissecting p53 tumor suppressor functions in vivo | Q34135695 | ||
| Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence | Q34196515 | ||
| Cellular targets for transformation by the adenovirus E1A proteins | Q34438094 | ||
| Use of human tissue to assess the oncogenic activity of melanoma-associated mutations | Q34716087 | ||
| PML is induced by oncogenic ras and promotes premature senescence | Q35201220 | ||
| Transcriptional regulation by p53: one protein, many possibilities | Q36436698 | ||
| Identification of a Novel p53 Functional Domain That Is Necessary for Mediating Apoptosis | Q38337319 | ||
| The codon 72 polymorphic variants of p53 have markedly different apoptotic potential | Q40672888 | ||
| Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1. | Q41414258 | ||
| p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes | Q41454039 | ||
| Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis | Q41563751 | ||
| Genome-wide analysis of p53 under hypoxic conditions | Q42934196 | ||
| Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer | Q44746842 | ||
| The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality | Q46111122 | ||
| Oncogene-induced senescence as an initial barrier in lymphoma development | Q46634165 | ||
| Induction of apoptosis in HeLa cells by trans-activation-deficient p53 | Q53461564 | ||
| p53 domains: suppression, transformation, and transactivation | Q58796385 | ||
| Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication | Q79314195 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | 1215-1220 | |
| P577 | publication date | 2008-01-23 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence | |
| P478 | volume | 105 |
| Q84583331 | 20 years studying p53 functions in genetically engineered mice |
| Q37546075 | AMP-activated protein kinase induces p53 by phosphorylating MDMX and inhibiting its activity |
| Q34621019 | Beyond effector caspase inhibition: Bcl2L12 neutralizes p53 signaling in glioblastoma |
| Q37466228 | Cytoplasmic functions of the tumour suppressor p53. |
| Q41850633 | Etoposide induces cell death via mitochondrial-dependent actions of p53. |
| Q54382805 | Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform |
| Q38176221 | Illuminating p53 function in cancer with genetically engineered mouse models |
| Q34042319 | In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models |
| Q37381179 | MEK plus PI3K/mTORC1/2 Therapeutic Efficacy Is Impacted by TP53 Mutation in Preclinical Models of Colorectal Cancer. |
| Q42017519 | On the role of FOX transcription factors in adipocyte differentiation and insulin-stimulated glucose uptake |
| Q37784324 | Oncogene-induced senescence: the bright and dark side of the response |
| Q28546901 | Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation |
| Q35795073 | Targeting the p53 signaling pathway in cancer therapy – the promises, challenges and perils |
| Q39013660 | The Transactivation Domains of the p53 Protein |
| Q37310208 | The p53 family and programmed cell death |
| Q35105986 | The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor. |
| Q34558399 | The sesquiterpene lactone dehydroleucodine triggers senescence and apoptosis in association with accumulation of DNA damage markers |
| Q39806153 | The transcriptional regulatory function of p53 is essential for suppression of mouse skin carcinogenesis and can be dissociated from effects on TGF-beta-mediated growth regulation |
| Q37412688 | Tumor suppressive functions of p53 |
| Q40101245 | Wild-type and Hupki (human p53 knock-in) murine embryonic fibroblasts: p53/ARF pathway disruption in spontaneous escape from senescence |
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