| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/0022-2836(90)90371-R |
| P8608 | Fatcat ID | release_zrxyrjfmejgeddntvxorj6vlyy |
| P698 | PubMed publication ID | 2258922 |
| P2093 | author name string | Milner J | |
| Medcalf EA | |||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 481-484 | |
| P577 | publication date | 1990-12-01 | |
| P1433 | published in | Journal of Molecular Biology | Q925779 |
| P1476 | title | Temperature-dependent switching between "wild-type" and "mutant" forms of p53-Val135. | |
| P478 | volume | 216 |
| Q68323916 | A conformation hypothesis for the suppressor and promoter functions ofp53in cell growth control and in cancer |
| Q28211719 | A role for Hsc70 in regulating nucleocytoplasmic transport of a temperature-sensitive p53 (p53Val-135) |
| Q36648425 | Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway |
| Q41227408 | Allosteric regulation of the thermostability and DNA binding activity of human p53 by specific interacting proteins. CRC Cell Transformation Group |
| Q41049816 | Alteration of p53 protein in C3H/10T1/2 cells morphologically transformed by gamma-rays in stationary phase. |
| Q38353498 | Analysis of p53 "latency" and "activation" by fluorescence correlation spectroscopy. Evidence for different modes of high affinity DNA binding. |
| Q51578869 | CHIP chaperones wild type p53 tumor suppressor protein. |
| Q55295894 | Close correlation between the dephosphorylation of p53 and growth suppression by transforming growth factor-beta 1 in nasopharyngeal carcinoma cells transduced with adenovirus early region genes. |
| Q40858485 | Conformational phenotype of p53 is linked to nuclear translocation |
| Q38313400 | Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants. |
| Q40297593 | Destabilizing missense mutations in the tumour suppressor protein p53 enhance its ubiquitination in vitro and in vivo |
| Q54611532 | Explaining the biological activity of transactivation-deficient p53 variants. |
| Q43043487 | Folding and misfolding mechanisms of the p53 DNA binding domain at physiological temperature |
| Q40973361 | Growth stimulation of murine fibroblasts by TGF-beta1 depends on the expression of a functional p53 protein |
| Q84551753 | Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions |
| Q39285924 | IPH-926 lobular breast cancer cells harbor a p53 mutant with temperature-sensitive functional activity and allow for profiling of p53-responsive genes |
| Q34366021 | Identification of PRC1 as the p53 target gene uncovers a novel function of p53 in the regulation of cytokinesis |
| Q41977775 | Increased salt concentration reversibly destabilizes p53 quaternary structure and sequence-specific DNA binding. |
| Q53552969 | Induction of Fas (CD95/APO-1) ligand is essential for p53-dependent apoptosis in an in vitro renal carcinoma model system. |
| Q74602392 | Inhibition of hTAFII32-binding implicated in the transcriptional repression by central regions of mutant p53 proteins |
| Q41532796 | Interaction of heat-shock protein 70 with p53 translated in vitro: evidence for interaction with dimeric p53 and for a role in the regulation of p53 conformation |
| Q40082372 | MDM2 chaperones the p53 tumor suppressor |
| Q40421511 | Mammalian p53 can function as a transcription factor in yeast |
| Q44531458 | Molecular characterization of oncostatin M-induced growth arrest of MCF-7 cells expressing a temperature-sensitive mutant of p53. |
| Q72993916 | Molecular evolution of the thermosensitive PAb1620 epitope of human p53 by DNA shuffling |
| Q36568304 | Proteolysis by calpains: a possible contribution to degradation of p53. |
| Q74189456 | Refolding and structural characterization of the human p53 tumor suppressor protein |
| Q36552986 | Role of cysteine residues in regulation of p53 function |
| Q42815910 | Screening the p53 status of human cell lines using a yeast functional assay |
| Q36797245 | Simian virus 40 can overcome the antiproliferative effect of wild-type p53 in the absence of stable large T antigen-p53 binding |
| Q27730258 | Solution structure of the tetrameric minimum transforming domain of p53 |
| Q34076012 | Strategies for manipulating the p53 pathway in the treatment of human cancer. |
| Q42590443 | Temperature sensitivity for conformation is an intrinsic property of wild-type p53. |
| Q41028721 | Temperature sensitivity of human wild-type and mutant p53 proteins expressed in vivo |
| Q40700411 | Temperature-sensitive ovarian carcinoma cell line (OvBH-1). |
| Q34290217 | The role of tetramerization in p53 function |
| Q35986418 | The tumor suppressor gene TP53: implications for cancer management and therapy |
| Q34055161 | Tight DNA binding and oligomerization are dispensable for the ability of p53 to transactivate target genes and suppress transformation. |
| Q34314048 | Tumor suppressor p53 mutations and breast cancer: a critical analysis |
| Q33729053 | Use of a yeast assay to detect functional alterations in p53 in prostate cancer: review and future directions |
| Q40872252 | Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA. |
| Q29622924 | Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6 |
| Q71627486 | Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys |
| Q40878189 | c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells |
| Q42666570 | p53 DNA binding can be modulated by factors that alter the conformational equilibrium |
| Q45306125 | p53 must be competent for transcriptional regulation to suppress tumor formation |
| Q33937620 | p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer |
| Q41502371 | p53Val135 temperature sensitive mutant suppresses growth of human breast cancer cells |
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