review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0960-7404(01)00018-4 |
P698 | PubMed publication ID | 11719028 |
P2093 | author name string | Shah SA | |
Callery MP | |||
Potter MW | |||
P2860 | cites work | Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes | Q74088744 |
Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53 | Q77764263 | ||
Inhibition of NF-kappa B activation in vitro and in vivo: role of 26S proteasome | Q77907913 | ||
UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells | Q24609948 | ||
Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation | Q24650561 | ||
The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis | Q24656114 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae | Q27939221 | ||
Cyclin is degraded by the ubiquitin pathway | Q28131704 | ||
Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2 | Q28237519 | ||
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules | Q28248180 | ||
Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin | Q28300614 | ||
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21 | Q28505037 | ||
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway | Q28615706 | ||
Cancer cell cycles | Q29547756 | ||
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB | Q29614706 | ||
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death | Q29614707 | ||
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B | Q29618194 | ||
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours | Q29618396 | ||
The ubiquitin system | Q29618565 | ||
The ubiquitin-proteasome proteolytic pathway | Q29618638 | ||
NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation | Q29618715 | ||
Suppression of TNF-alpha-induced apoptosis by NF-kappaB | Q29618717 | ||
Proteasome inhibitors: valuable new tools for cell biologists | Q29620573 | ||
Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells. | Q31107812 | ||
Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter | Q33559371 | ||
26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer | Q33950784 | ||
Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress | Q33997846 | ||
Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer | Q34415244 | ||
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. | Q34415250 | ||
Catalysis by a multiprotein IkappaB kinase complex | Q34743658 | ||
DNA damage induces phosphorylation of the amino terminus of p53 | Q35199554 | ||
Apoptosis induced by anticancer drugs | Q35233723 | ||
Proteasomes play an essential role in thymocyte apoptosis | Q35904377 | ||
Activation of the cell death program by inhibition of proteasome function | Q35964722 | ||
Control of programmed cyclin destruction in a cell-free system | Q36221788 | ||
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control | Q36580820 | ||
Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway | Q36648425 | ||
The mechanism and functions of ATP-dependent proteases in bacterial and animal cells | Q36736334 | ||
Degradation of nuclear oncoproteins by the ubiquitin system in vitro | Q37361143 | ||
Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer | Q37376029 | ||
Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B | Q37649750 | ||
The multicatalytic proteinase complex, a major extralysosomal proteolytic system | Q37901108 | ||
The role of cyclin synthesis, modification and destruction in the control of cell division. | Q38262781 | ||
Dominoes and clocks: the union of two views of the cell cycle | Q38718174 | ||
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells | Q39795545 | ||
Apoptosis in cancer therapy: crossing the threshold | Q40694262 | ||
Apoptosis. Its significance in cancer and cancer therapy | Q40739570 | ||
Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts | Q40979308 | ||
Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons. | Q41076164 | ||
Enhancement of CPP32-like activity in the TNF-treated U937 cells by the proteasome inhibitors | Q41185868 | ||
Effects on NF-kappa B1/p105 processing of the interaction between the HTLV-1 transactivator Tax and the proteasome | Q41197961 | ||
Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone | Q41213327 | ||
Cell and environment interactions in tumor microregions: the multicell spheroid model | Q41280817 | ||
The ubiquitin-mediated proteolytic pathway as a therapeutic area | Q41340821 | ||
Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination | Q41589996 | ||
Apoptosis induction resulting from proteasome inhibition | Q42079940 | ||
Apoptosis-inducing levels of UV radiation and proteasome inhibitors produce opposite effects on p21(WAF1) in human melanoma cells | Q42487557 | ||
Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids | Q42537232 | ||
Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB. | Q43584710 | ||
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. | Q45993768 | ||
Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids | Q48331723 | ||
Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells. | Q52973572 | ||
alpha-Aminoboronic acid derivatives: effective inhibitors of aminopeptidases | Q68871372 | ||
Structure of lactacystin, a new microbial metabolite which induces differentiation of neuroblastoma cells | Q70114212 | ||
Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells | Q70881911 | ||
Prevention of cisplatin-DNA adduct repair and potentiation of cisplatin-induced apoptosis in ovarian carcinoma cells by proteasome inhibitors | Q73011657 | ||
p21WAF1 expression is associated with improved survival after adjuvant chemoradiation for pancreatic cancer | Q73030013 | ||
Peptidyl aldehyde inhibitors of proteasome induce apoptosis rapidly in mouse lymphoma RVC cells | Q73303188 | ||
Detailed analysis of cell cycle kinetics upon proteasome inhibition | Q73508420 | ||
P433 | issue | 1-2 | |
P921 | main subject | ubiquitin-proteasome system | Q47175589 |
P304 | page(s) | 43-52 | |
P577 | publication date | 2001-07-01 | |
P1433 | published in | Surgical Oncology | Q14421678 |
P1476 | title | Ubiquitin proteasome pathway: implications and advances in cancer therapy | |
P478 | volume | 10 |
Q44195479 | 15-Deoxy-delta12,14-prostaglandin J2-induced apoptosis does not require PPARgamma in breast cancer cells |
Q44380190 | A short, stereocontrolled, and practical synthesis of alpha-methylomuralide, a potent inhibitor of proteasome function |
Q39652073 | Antitrypanosomal activities of proteasome inhibitors |
Q33960631 | Cachexia: a therapeutic approach beyond cytokine antagonism |
Q40631657 | Calcium- and proteasome-dependent degradation of the JNK scaffold protein islet-brain 1. |
Q37962590 | Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors |
Q45784186 | Evidence for the Critical Roles of NF-κB p65 and Specificity Proteins in the Apoptosis-Inducing Activity of Proteasome Inhibitors in Leukemia Cells |
Q40502949 | Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cells |
Q37314468 | Follicular thyroid cancer cell growth inhibition by proteosome inhibitor MG132 |
Q35038788 | Heat shock protein and proteasome targeting agents |
Q35548615 | Immunoproteasomes and immunosenescence |
Q37480580 | MG-132 inhibits carcinoid growth and alters the neuroendocrine phenotype |
Q36642830 | MG132, a proteasome inhibitor, induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion |
Q24310815 | Mapping and structural dissection of human 20 S proteasome using proteomic approaches |
Q54602513 | Mitogen-activated protein kinase inhibitors differently affect the growth inhibition and death of a proteasome inhibitor, MG132-treated human pulmonary fibroblast cells. |
Q38961037 | Nrf2 silencing to inhibit proteolytic defense induced by hyperthermia in HT22 cells. |
Q44428903 | Proteasome inhibitors induce intracellular protein aggregation and cell death by an oxygen-dependent mechanism. |
Q34633196 | Regulation of apoptosis by the ubiquitin and proteasome pathway. |
Q37188091 | Role of proteasomes in cellular regulation |
Q40114381 | Synthetic lethal short hairpin RNA screening reveals that ring finger protein 183 confers resistance to trametinib in colorectal cancer cells |
Q36897340 | Targeted therapies in small-cell lung cancer |
Q36305395 | The Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesis |
Q39693556 | Treatment with p38 inhibitor intensifies the death of MG132-treated As4.1 juxtaglomerular cells via the enhancement of GSH depletion |
Q42176007 | WITHDRAWN: Evidence for the critical roles of NF-κB p65 and specificity proteins in the apoptosis-inducing activity of proteasome inhibitors in leukemia cells |
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