MG132, a proteasome inhibitor, induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion

scientific article published on 19 January 2012

MG132, a proteasome inhibitor, induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/OR.2012.1642
P932PMC publication ID3583605
P698PubMed publication ID22266922
P5875ResearchGate publication ID221768008

P2093author name stringSuhn Hee Kim
Woo Hyun Park
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Effects of the proteasome inhibitor bortezomib alone and in combination with chemotherapy in the A549 non-small-cell lung cancer cell lineQ40545203
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Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cellsQ42806146
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The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 statusQ46706369
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Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosisQ33905351
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The role of ROS and RNS in regulating life and death of blood monocytesQ35699294
The proteasome: a suitable antineoplastic targetQ35762448
Gene expression profiling in non-small cell lung cancer: from molecular mechanisms to clinical applicationQ35783088
The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanismQ35848514
Activation of the cell death program by inhibition of proteasome functionQ35964722
Mitochondrial ROS-induced ROS release: an update and reviewQ36531183
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Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosisQ37131361
P433issue4
P921main subjectcell deathQ2383867
P304page(s)1284-1291
P577publication date2012-01-19
P1433published inOncology ReportsQ7092098
P1476titleMG132, a proteasome inhibitor, induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion
P478volume27