Histamine H4 receptor antagonists as potent modulators of mammalian vestibular primary neuron excitability

scientific article published on October 2012

Histamine H4 receptor antagonists as potent modulators of mammalian vestibular primary neuron excitability is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1476-5381.2012.02049.X
P932PMC publication ID3575788
P698PubMed publication ID22624822
P5875ResearchGate publication ID225042964

P2093author name stringC Chabbert
C Travo
G Desmadryl
E Wersinger
A Saleur
A Broussy
A Brugeaud
J Dyhrfjeld-Johnsen
S Gaboyard-Niay
P2860cites workMolecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytesQ24290193
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Histamine and betahistine in the treatment of vertigo: elucidation of mechanisms of actionQ34432126
Coupling of histamine H3 receptors to neuronal Na+/H+ exchange: a novel protective mechanism in myocardial ischemiaQ34500237
Highly potent and selective ligands for histamine H3-receptorsQ34661299
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A new generation of anti-histamines: Histamine H4 receptor antagonists on their way to the clinicQ37593489
Low-voltage-activated potassium channels underlie the regulation of intrinsic firing properties of rat vestibular ganglion cellsQ39097136
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Agonist-biased signaling at the histamine H4 receptor: JNJ7777120 recruits β-arrestin without activating G proteins.Q39623360
Molecular determinants of ligand binding to H4R species variantsQ39747626
Histamine H(4) receptors regulate ACTH release in AtT-20 cells.Q39987892
Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET.Q40110003
Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: potent human histamine h(4) antagonistsQ40338159
Synthesis and structure-activity relationships of indole and benzimidazole piperazines as histamine H(4) receptor antagonists.Q40509880
Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulationQ40558411
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Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivativesQ41888634
Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptorQ42024153
Effects of betahistine at histamine H3 receptors: mixed inverse agonism/agonism in vitro and partial inverse agonism in vivoQ42472544
Dose- and duration-dependent effects of betahistine dihydrochloride treatment on histamine turnover in the cat.Q42485327
Betahistine produces post-synaptic inhibition of the excitability of the primary afferent neurons in the vestibular endorgansQ42511933
Histamine (H3) receptors modulate the excitatory amino acid receptor response of the vestibular afferentsQ42674170
The vestibular nerve of the chinchilla. II. Relation between afferent response properties and peripheral innervation patterns in the semicircular canalsQ43471697
Localization of histamine H4 receptors in the central nervous system of human and rat.Q46153368
A national survey amongst UK otolaryngologists regarding the treatment of Ménière's diseaseQ46436639
Actions of betahistine at histamine receptors in the brainQ48495593
Conformational changes in the M2 muscarinic receptor induced by membrane voltage and agonist bindingQ48682233
The effect of Serc (betahistine hydrochloride) on the circulation of the inner ear in experimental animals.Q54492663
3,3'-Iminodipropionitrile induces neurofilament accumulations in the perikarya of rat vestibular ganglion neuronsQ71341150
The behavioral syndrome caused by 3,3'-iminodipropionitrile and related nitriles in the rat is associated with degeneration of the vestibular sensory hair cellsQ72628405
Comparison of behavioral, vestibular, and axonal effects of subchronic IDPN in the ratQ73308230
Effects of betahistine on vestibular receptors of the frogQ77193890
Histamine excites neurones in the human submucous plexus through activation of H1, H2, H3 and H4 receptorsQ80604568
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)905-916
P577publication date2012-10-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleHistamine H4 receptor antagonists as potent modulators of mammalian vestibular primary neuron excitability
P478volume167

Reverse relations

cites work (P2860)
Q48491449A search for functional histamine H4 receptors in the human, guinea pig and mouse brain
Q46489053Adjustment of the dynamic weight distribution as a sensitive parameter for diagnosis of postural alteration in a rodent model of vestibular deficit
Q30371381Correlation between afferent rearrangements and behavioral deficits after local excitotoxic insult in the mammalian vestibule: a rat model of vertigo symptoms.
Q48134020Effect of M-current modulation on mammalian vestibular responses to transient head motion.
Q37124388Evidence for a Role of Orexin/Hypocretin System in Vestibular Lesion-Induced Locomotor Abnormalities in Rats
Q34025192Histamine H4 receptor as a new therapeutic target for choroidal neovascularization in age-related macular degeneration
Q64287379Histamine H4 receptor gene polymorphisms: a potential contributor to Meniere disease
Q38128902Histamine pharmacology: four years on.
Q26827568International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors
Q53184123Localization of histamine (H1, H2, H3 and H4) receptors in mouse inner ear.
Q38603260Motion Sickness: Current Knowledge and Recent Advance
Q42367598Neuropharmacological Targets for Drug Action in Vestibular Sensory Pathways.
Q38248956Novel histamine H4 receptor ligands and their potential therapeutic applications: an update.
Q58562898To scratch an itch: Establishing a mouse model to determine active brain areas involved in acute histaminergic itch
Q36175380Transient alteration of the vestibular calyceal junction and synapse in response to chronic ototoxic insult in rats

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