Histamine and betahistine in the treatment of vertigo: elucidation of mechanisms of action

scientific article

Histamine and betahistine in the treatment of vertigo: elucidation of mechanisms of action is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1042261289
P356DOI10.2165/00023210-200115110-00004
P698PubMed publication ID11700150
P5875ResearchGate publication ID11654710

P2093author name stringSterkers O
Lacour M
P2860cites workBetahistine increases vestibular blood flowQ30652932
The vascular mechanism of action of betahistine in the inner ear of the guinea pig.Q32066302
Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptorQ34249836
The effects of two anti-vertigo drugs (betahistine and prochlorperazine) on driving skillsQ34358976
A third histamine receptor subtype: Characterisation, localisation and functions of the H3-receptorQ36586117
Neuronal regulation of cochlear blood flow in the guinea-pigQ36717299
Atrial natriuretic peptide participates in the regulation of vestibular blood flowQ36795664
Histaminergic Mechanisms in BrainQ37488169
Histamine in the treatment of vertigoQ37778234
Distribution, properties, and functional characteristics of three classes of histamine receptorQ37885674
Histamine as a transmitter in brainQ38159823
Recovery of head postural control following unilateral vestibular neurectomy in the cat. Neck muscle activity and neuronal correlates in Deiters' nucleiQ38567525
Cochlear blood flow in response to vasodilating drugs and some related agentsQ39106343
Microiontophoresis of acetylcholine, histamine and their antagonists on neurones in the medial and lateral vestibular nuclei of the catQ39132917
Minireview: Histamine receptors in brainQ39289045
Histamine as a neuroregulatorQ39440869
Histamine as a Neurotransmitter in Mammalian Brain: Neurochemical EvidenceQ40083567
'Vestibular compensation': neural plasticity and its relations to functional recovery after labyrinthine lesions in frogs and other vertebratesQ40418328
Vestibular control of posture and gait.Q40828733
Corticovestibular interactions: anatomy, electrophysiology, and functional considerationsQ40873327
Antivertigo medications and drug-induced vertigo. A pharmacological reviewQ40961261
Histamine and related substances influence neurotransmission in the semicircular canalQ41424454
Effects of diphenhydramine and dimenhydrinate on vestibular neuronal activity of cat: a search for the locus of their antimotion sickness action.Q42231810
Fos expression in the rat brain after exposure to gravito-inertial force changesQ42486447
Medial vestibular nucleus in the guinea-pig: histaminergic receptors. II. An in vivo studyQ42622310
A detailed mapping of histamine H1-receptors in guinea-pig central nervous system established by autoradiography with [125I]iodobolpyramineQ46554902
The binding of [3H]mepyramine to histamine H1 receptors in guinea-pig brainQ46722972
Effect of drug therapy on compensation from vestibular injuryQ46944892
Fos expression in the cat brainstem after unilateral vestibular neurectomyQ48253470
Medial vestibular nucleus in the guinea-pig: histaminergic receptors. I. An in vitro studyQ48368564
Actions of betahistine at histamine receptors in the brainQ48495593
effects of diazepam and dimenhydrinate on the resting activity of the vestibular neuronQ48518181
Histamine immunoreactivity changes in vestibular-lesioned and histaminergic-treated catsQ48660648
Effects of anti-vertigo drugs on medial vestibular nucleus neurons activated by horizontal rotationQ48826350
Properties and regional distribution of histidine decarboxylase in rat brainQ48887147
Inhibitory effect of betahistine on polysynaptic neurons in the lateral vestibular nucleusQ49032078
Distribution of histaminergic axonal fibres in the vestibular nuclei of the cat.Q49053023
Histamine depolarizes rat medial vestibular nucleus neurons recorded intracellularly in vitroQ49098441
Betahistine-induced vascular effects in the rat cochlea.Q50532832
Drug effects on postlabyrinthectomy nystagmus.Q52727501
Physiology of peripheral neurons innervating otolith organs of the squirrel monkey. III. Response dynamics.Q52844317
Response to static tilts of peripheral neurons innervating otolith organs of the squirrel monkeyQ52964855
Effects of histamine and betahistine on rat medial vestibular nucleus neurones: possible mechanism of action of anti-histaminergic drugs in vertigo and motion sicknessQ53875138
The effect of Serc (betahistine hydrochloride) on the circulation of the inner ear in experimental animals.Q54492663
The Vestibular Blood Flow during CO2-Breathing in RabbitsQ58079113
Responses of peripheral vestibular neurons to angular and linear accelerations in the squirrel monkeyQ67512505
Neurochemical mechanisms of recovery from peripheral vestibular lesions (vestibular compensation)Q67801789
Effect of betahistine dihydrochloride on induced vestibular nystagmus: a double blind studyQ69018556
Mechanisms of recovery following unilateral labyrinthectomy: a reviewQ69520016
[Compensation deficits in posture and kinetics following unilateral vestibular neurectomy in cats. The role of sensorimotor activity]Q70713465
Betahistine dihydrochloride treatment facilitates vestibular compensation in the catQ72145042
Effect of unilateral vestibular stimulation on histamine release from the hypothalamus of rats in vivoQ72741908
Dose-dependent effect of betahistine on the vestibulo-ocular reflex: a double-blind, placebo controlled study in patients with paroxysmal vertigoQ73829719
Effects of betahistine on vestibular receptors of the frogQ77193890
P433issue11
P304page(s)853-870
P577publication date2001-01-01
P1433published inCNS DrugsQ5013183
P1476titleHistamine and betahistine in the treatment of vertigo: elucidation of mechanisms of action
P478volume15

Reverse relations

cites work (P2860)
Q46983316A Comparison of the Effects and Side Effects of Oral Betahistine with Injectable Promethazine in the Treatment of Acute Peripheral Vertigo in Emergency
Q36099400Assessment of pharmacology and potential anti-obesity properties of H3 receptor antagonists/inverse agonists
Q37091787Benign paroxysmal positional vertigo: a study of two manoeuvres with and without betahistine.
Q55407927Betahistine Treatment in a Cat Model of Vestibular Pathology: Pharmacokinetic and Pharmacodynamic Approaches.
Q41877165Betahistine as an add-on: The magic bullet for postoperative nausea, vomiting and dizziness after middle ear surgery?
Q37126812Betahistine in the treatment of Ménière's disease.
Q37072674Betahistine in the treatment of vertiginous syndromes: a meta-analysis
Q89729736Betahistine, prevents kindling, ameliorates the behavioral comorbidities and neurodegeneration induced by pentylenetetrazole
Q31069695Betahistine: a retrospective synopsis of safety data
Q34805860Changes in Histamine Receptors (H1, H2, and H3) Expression in Rat Medial Vestibular Nucleus and Flocculus after Unilateral Labyrinthectomy: Histamine Receptors in Vestibular Compensation
Q48585081Changes in the histaminergic system during vestibular compensation in the cat.
Q42661731Comparable efficacy and tolerability between twice daily and three times daily betahistine for Ménière's disease
Q34035274Effect of a fixed combination of nimodipine and betahistine versus betahistine as monotherapy in the long-term treatment of Ménière's disease: a 10-year experience
Q36328384Effectiveness of betahistine (48 mg/day) in patients with vestibular vertigo during routine practice: The VIRTUOSO study
Q36619798Histamine H4 receptor antagonists as potent modulators of mammalian vestibular primary neuron excitability
Q64287379Histamine H4 receptor gene polymorphisms: a potential contributor to Meniere disease
Q48397741Histaminergic and glycinergic modulation of GABA release in the vestibular nuclei of normal and labyrinthectomised rats
Q92976254Measuring dynamic Eustachian tube function using tympanometry in a pressure chamber: the effect of nasal betahistine application
Q47650690Na(+) -Ca(2+) Exchanger, Leak K(+) Channel and Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Comediate the Histamine-Induced Excitation on Rat Inferior Vestibular Nucleus Neurons
Q24624927Neuropharmacology of vestibular system disorders
Q28302554Optimizing the pharmacological component of integrated balance therapy
Q37151158Postsynaptic mechanisms underlying the excitatory action of histamine on medial vestibular nucleus neurons in rats
Q47266542Reducing antipsychotic-induced weight gain in schizophrenia: a double-blind placebo-controlled study of reboxetine-betahistine combination
Q39365824Residual Dizziness after Successful Repositioning Maneuver for Idiopathic Benign Paroxysmal Positional Vertigo: A Review.
Q48196961Safety, tolerability and pharmacokinetics of 2-pyridylacetic acid, a major metabolite of betahistine, in a phase 1 dose escalation study in subjects with ADHD.

Search more.