scholarly article | Q13442814 |
P2093 | author name string | Chen MY | |
Maldarelli F | |||
Strebel K | |||
Willey RL | |||
P2860 | cites work | Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export | Q24644301 |
Prediction of protein conformation | Q28240456 | ||
Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural proteins | Q29622958 | ||
Influenza virus M2 protein has ion channel activity | Q34248853 | ||
Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes | Q36656019 | ||
A glutamine residue in the membrane-associating domain of the bovine papillomavirus type 1 E5 oncoprotein mediates its binding to a transmembrane component of the vacuolar H(+)-ATPase | Q36656196 | ||
Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4 | Q36687143 | ||
The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release | Q36800610 | ||
Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein | Q36830393 | ||
44-amino-acid E5 transforming protein of bovine papillomavirus requires a hydrophobic core and specific carboxyl-terminal amino acids | Q36846314 | ||
Cell surface expression and orientation in membranes of the 44-amino-acid SH protein of simian virus 5. | Q36871873 | ||
Influenza A virus M2 protein: monoclonal antibody restriction of virus growth and detection of M2 in virions | Q36878521 | ||
Identification and predicted sequence of a previously unrecognized small hydrophobic protein, SH, of the paramyxovirus simian virus 5. | Q36904749 | ||
Characterization of foot-and-mouth disease virus gene products with antisera against bacterially synthesized fusion proteins | Q40125935 | ||
Structural characteristics of the M2 protein of influenza A viruses: evidence that it forms a tetrameric channel | Q41177473 | ||
The amino-terminal structures that determine topological orientation of cytochrome P-450 in microsomal membrane. | Q41240751 | ||
A tripartite structure of the signals that determine protein insertion into the endoplasmic reticulum membrane | Q41574268 | ||
The 9-kDa hydrophobic protein encoded at the 3' end of the porcine transmissible gastroenteritis coronavirus genome is membrane-associated | Q41642824 | ||
Site-directed mutations in the Sindbis virus 6K protein reveal sites for fatty acylation and the underacylated protein affects virus release and virion structure | Q41741534 | ||
Requirements for the membrane insertion of signal-anchor type proteins | Q41828297 | ||
A novel gene of HIV-1, vpu, and its 16-kilodalton product | Q42656133 | ||
Human erythrocyte membrane sialoglycoprotein beta. The cDNA sequence suggests the absence of a cleaved N-terminal signal sequence | Q42855791 | ||
Plasmid vectors for high-efficiency expression controlled by the promoter of coliphage lambda | Q45139427 | ||
The HIV 'A' (sor) gene product is essential for virus infectivity | Q45847960 | ||
Preparation of microsomal membranes for cotranslational protein translocation | Q49487241 | ||
Antibody response to viral proteins U (vpu) and R (vpr) in HIV-1-infected individuals. | Q54720086 | ||
The folding and cell surface expression of CD4 requires glycosylation | Q67749632 | ||
In vitro membrane binding of the translation products of the carlavirus 7-kDa protein genes | Q67917867 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | membrane protein | Q423042 |
P304 | page(s) | 5056-5061 | |
P577 | publication date | 1993-08-01 | |
P1433 | published in | Journal of Virology | Q1251128 |
P1476 | title | Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein | |
P478 | volume | 67 |
Q34220959 | A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction. |
Q28276184 | A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif |
Q30968332 | Antiviral efficacy of the novel compound BIT225 against HIV-1 release from human macrophages. |
Q39479945 | Association of Vpu with hepatitis C virus NS3/4A stimulates transcription of type 1 human immunodeficiency virus |
Q28544943 | Atomistic detailed mechanism and weak cation-conducting activity of HIV-1 Vpu revealed by free energy calculations |
Q35852056 | Augmentation of virus secretion by the human immunodeficiency virus type 1 Vpu protein is cell type independent and occurs in cultured human primary macrophages and lymphocytes |
Q33519521 | BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction |
Q41816646 | BST-2 Diminishes HIV-1 Infectivity |
Q43628285 | Background K(2P) channels KCNK3/9/15 limit the budding of cell membrane-derived vesicles. |
Q35291655 | Bacteria-based analysis of HIV-1 Vpu channel activity |
Q35857341 | Both linear and discontinuous ribosome scanning are used for translation initiation from bicistronic human immunodeficiency virus type 1 env mRNAs |
Q33782459 | CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway |
Q34291056 | Cell-cell spread of human immunodeficiency virus type 1 overcomes tetherin/BST-2-mediated restriction in T cells |
Q39886418 | Characterization of HIV-2 chimeric viruses unable to use CCR5 and CXCR4 coreceptors |
Q34180848 | Comparative structural studies of Vpu peptides in phospholipid monolayers by x-ray scattering. |
Q57178486 | Compatibility of Vpu-like activity in the four groups of primate immunodeficiency viruses |
Q36744298 | Correlation of the structural and functional domains in the membrane protein Vpu from HIV-1. |
Q27485043 | Cytopathic Mechanisms of HIV-1 |
Q34062105 | Cytoskeleton association and virion incorporation of the human immunodeficiency virus type 1 Vif protein. |
Q34416492 | Determinants of tetherin antagonism in the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein |
Q24646897 | Differential activities of the human immunodeficiency virus type 1-encoded Vpu protein are regulated by phosphorylation and occur in different cellular compartments |
Q42211475 | Downmodulation of CCR7 by HIV-1 Vpu results in impaired migration and chemotactic signaling within CD4⁺ T cells |
Q34408687 | Epitope tags beside the N-terminal cytoplasmic tail of human BST-2 alter its intracellular trafficking and HIV-1 restriction |
Q34684340 | Evidence that Vpu modulates HIV-1 Gag-envelope interaction towards envelope incorporation and infectivity in a cell type dependent manner |
Q58869570 | Evidences for Viral Strain Selection in Late Stages of HIV Infection: An Analysis of Vpu Alleles |
Q39688173 | Expression, purification and preliminary crystallographic analysis of recombinant human small glutamine-rich tetratricopeptide-repeat protein |
Q36639042 | Expression, purification, and activities of full-length and truncated versions of the integral membrane protein Vpu from HIV-1 |
Q33737672 | Functional domains within the human immunodeficiency virus type 2 envelope protein required to enhance virus production |
Q24523647 | Functional interaction of human immunodeficiency virus type 1 Vpu and Gag with a novel member of the tetratricopeptide repeat protein family. |
Q36629169 | Genomic cloning and complete sequence analysis of a highly divergent African human immunodeficiency virus isolate |
Q36857081 | HIV accessory genes Vif and Vpu. |
Q41421578 | HIV accessory proteins as therapeutic targets |
Q34033122 | HIV accessory proteins: multifunctional components of a complex system. |
Q37384691 | HIV-1 Vpu - an ion channel in search of a job. |
Q39175785 | HIV-1 Vpu affects the anterograde transport and the glycosylation pattern of NTB-A. |
Q42031796 | HIV-1 Vpu mediated downregulation of CD155 requires alanine residues 10, 14 and 18 of the transmembrane domain |
Q21089617 | HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation |
Q24619066 | HIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanisms |
Q24646984 | HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes |
Q33671675 | HIV-1-based defective lentiviral vectors efficiently transduce human monocytes-derived macrophages and suppress replication of wild-type HIV-1 |
Q34485169 | Identification of Amino Acids in the Human Tetherin Transmembrane Domain Responsible for HIV-1 Vpu Interaction and Susceptibility |
Q35028829 | Identification of Residues in the BST-2 TM Domain Important for Antagonism by HIV-1 Vpu Using a Gain-of-Function Approach |
Q39769799 | Identification of amino acids within the second alpha helical domain of the human immunodeficiency virus type 1 Vpu that are critical for preventing CD4 cell surface expression |
Q45765997 | Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells |
Q37120188 | Identification of calcium-modulating cyclophilin ligand as a human host restriction to HIV-1 release overcome by Vpu. |
Q35382088 | In COS cells Vpu can both stabilize tetherin expression and counteract its antiviral activity |
Q44829576 | Interaction of amiloride and one of its derivatives with Vpu from HIV-1: a molecular dynamics simulation |
Q40042729 | Ion Channel Activity of Vpu Proteins Is Conserved throughout Evolution of HIV-1 and SIV. |
Q39538757 | Ion channel activity of HIV-1 Vpu is dispensable for counteraction of CD317. |
Q46061288 | Long-chain polyunsaturated fatty acids as anti-HIV supplementation during breastfeeding |
Q40927400 | MARCH8 inhibits HIV-1 infection by reducing virion incorporation of envelope glycoproteins. |
Q34176789 | Mapping the energy surface of transmembrane helix-helix interactions |
Q37988058 | Mechanism of function of viral channel proteins and implications for drug development |
Q38211428 | Mechanisms underlying HIV-1 Vpu-mediated viral egress |
Q73055727 | Membrane interactions and alignment of structures within the HIV-1 Vpu cytoplasmic domain: effect of phosphorylation of serines 52 and 56 |
Q34314053 | Modification of membrane permeability by animal viruses. |
Q30397761 | Modulation of HIV-1-host interaction: role of the Vpu accessory protein |
Q40015792 | Modulation of beta-catenin and E-cadherin interaction by Vpu increases human immunodeficiency virus type 1 particle release |
Q37307754 | Modulation of the severe CD4+ T-cell loss caused by a pathogenic simian-human immunodeficiency virus by replacement of the subtype B vpu with the vpu from a subtype C HIV-1 clinical isolate |
Q39820667 | Molecular biology and pathogenesis of animal lentivirus infections. |
Q36636712 | Molecular biology of the human immunodeficiency virus accessory proteins |
Q30332722 | Molecular dynamics simulation of human immunodeficiency virus protein U (Vpu) in lipid/water Langmuir monolayer. |
Q35040322 | Molecular dynamics simulations reveal the HIV-1 Vpu transmembrane protein to form stable pentamers |
Q21131559 | Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps |
Q39642301 | Mutational analysis of the human immunodeficiency virus type 1 Vpu transmembrane domain that promotes the enhanced release of virus-like particles from the plasma membrane of mammalian cells. |
Q28257691 | Mutual functional destruction of HIV-1 Vpu and host TASK-1 channel |
Q44426365 | Naturally occurring amino acid substitutions in the HIV-2 ROD envelope glycoprotein regulate its ability to augment viral particle release. |
Q40087952 | Oligomerization of the human immunodeficiency virus type 1 (HIV-1) Vpu protein--a genetic, biochemical and biophysical analysis |
Q33933111 | Polarity changes in the transmembrane domain core of HIV-1 Vpu inhibits its anti-tetherin activity |
Q37950254 | Protein intrinsic disorder as a flexible armor and a weapon of HIV-1. |
Q35886576 | Putative alpha-helical structures in the human immunodeficiency virus type 1 Vpu protein and CD4 are involved in binding and degradation of the CD4 molecule |
Q37274112 | Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells. |
Q33640055 | Regulation of virus release by the macrophage-tropic human immunodeficiency virus type 1 AD8 isolate is redundant and can be controlled by either Vpu or Env. |
Q34701164 | Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum. |
Q33926185 | Requirements of the membrane proximal tyrosine and dileucine-based sorting signals for efficient transport of the subtype C Vpu protein to the plasma membrane and in virus release |
Q80966892 | SARS coronavirus E protein forms cation-selective ion channels |
Q40405593 | Scrambling of the amino acids within the transmembrane domain of Vpu results in a simian-human immunodeficiency virus (SHIVTM) that is less pathogenic for pig-tailed macaques. |
Q35383228 | Separable determinants of subcellular localization and interaction account for the inability of group O HIV-1 Vpu to counteract tetherin |
Q36627720 | Sequences present in the cytoplasmic domain of CD4 are necessary and sufficient to confer sensitivity to the human immunodeficiency virus type 1 Vpu protein. |
Q35758867 | Serine Phosphorylation of HIV-1 Vpu and Its Binding to Tetherin Regulates Interaction with Clathrin Adaptors |
Q84315458 | Severe acute respiratory syndrome coronavirus spike protein counteracts BST2‐mediated restriction of virus‐like particle release |
Q28360964 | Structural studies of the HIV-1 accessory protein Vpu in langmuir monolayers: synchrotron X-ray reflectivity |
Q35217961 | Structure-function correlates of Vpu, a membrane protein of HIV-1. |
Q38796348 | Targeting the Channel Activity of Viroporins. |
Q30393226 | Tetherin Antagonism by HIV-1 Group M Nef Proteins |
Q33674461 | Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity. |
Q30497822 | Tetherin restricts direct cell-to-cell infection of HIV-1. |
Q30382590 | Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains. |
Q35206874 | The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release. |
Q40467610 | The Human Immunodeficiency Virus Type 1 Vpu Protein: Roles in Virus Release and CD4 Downregulation |
Q24680307 | The Vpu protein of human immunodeficiency virus type 1 forms cation-selective ion channels |
Q36824020 | The Vpu-interacting Protein SGTA Regulates Expression of a Non-glycosylated Tetherin Species |
Q35854386 | The envelope glycoprotein of human immunodeficiency virus type 2 enhances viral particle release: a Vpu-like factor? |
Q35097640 | The expression of HIV-1 Vpu in monocytes causes increased secretion of TGF-β that activates profibrogenic genes in hepatic stellate cells |
Q21245050 | The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu |
Q45323651 | The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells. |
Q35873115 | The human immunodeficiency virus (HIV) type 2 envelope protein is a functional complement to HIV type 1 Vpu that enhances particle release of heterologous retroviruses. |
Q36669879 | The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection. |
Q36377062 | The human immunodeficiency virus type 1 (HIV-1) Vpu protein interferes with an early step in the biosynthesis of major histocompatibility complex (MHC) class I molecules |
Q24676509 | The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation |
Q24670601 | The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors |
Q44572420 | The presence of the casein kinase II phosphorylation sites of Vpu enhances the CD4(+) T cell loss caused by the simian-human immunodeficiency virus SHIV(KU-lbMC33) in pig-tailed macaques |
Q40244531 | The small envelope protein of porcine reproductive and respiratory syndrome virus possesses ion channel protein-like properties |
Q43639895 | The structure of the HIV-1 Vpu ion channel: modelling and simulation studies. |
Q41984737 | The transmembrane domain of BST-2 determines its sensitivity to down-modulation by human immunodeficiency virus type 1 Vpu. |
Q35854362 | The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains. |
Q40008929 | The vpu protein of human immunodeficiency virus type 1 plays a protective role against virus-induced apoptosis in primary CD4(+) T lymphocytes |
Q35665886 | Transmembrane domain determinants of CD4 Downregulation by HIV-1 Vpu. |
Q38739273 | Various plus unique: Viral protein U as a plurifunctional protein for HIV-1 replication |
Q37505647 | Viral channel-forming proteins. |
Q34623321 | Viral ion channels: structure and function. |
Q34230206 | Viroporins. |
Q26801489 | Vpu Protein: The Viroporin Encoded by HIV-1 |
Q35943823 | Vpu augments the initial burst phase of HIV-1 propagation and downregulates BST2 and CD4 in humanized mice |
Q37115275 | Vpu enhances HIV-1 virus release in the absence of Bst-2 cell surface down-modulation and intracellular depletion |
Q35217957 | Vpu from HIV-1 on an atomic scale: experiments and computer simulations. |
Q33638829 | Vpu increases susceptibility of human immunodeficiency virus type 1-infected cells to fas killing. |
Q33455532 | Vpu matchmakers as a therapeutic strategy for HIV infection |
Q39363423 | Vpu-dependent block to incorporation of GaLV Env into lentiviral vectors |
Q40149831 | vpu transmembrane peptide structure obtained by site-specific fourier transform infrared dichroism and global molecular dynamics searching |
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