Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties

scientific article published on 31 October 2012

Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPCELL.00287.2012
P932PMC publication ID3587378
P698PubMed publication ID23114965
P5875ResearchGate publication ID232744269

P2093author name stringSebastian Bachmann
Robert A Fenton
Alicia A McDonough
Anne D Riquier-Brison
Mien T X Nguyen
Arvid B Maunsbach
Alan S Yu
Donna H Lee
P2860cites workLarge-scale phosphoproteomic analysis of membrane proteins in renal proximal and distal tubuleQ24619838
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletionQ28255750
Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1Q28268511
Vasopressin induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubuleQ28281414
Angiotensin II induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter independent of aldosteroneQ28290886
Blue native PAGEQ28296330
The renal thiazide-sensitive Na-Cl cotransporter as mediator of the aldosterone-escape phenomenonQ28344122
The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertensionQ38690025
Effect of angiotensin II on the WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidneyQ39736626
The molecular basis of inherited hypokalemic alkalosis: Bartter's and Gitelman's syndromesQ41245908
Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathwayQ41966666
Immunoelectron microscopic localization of the electrogenic Na/HCO(3) cotransporter in rat and ambystoma kidney.Q42496512
Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathwaysQ42757015
Short-term stimulation of the thiazide-sensitive Na+-Cl- cotransporter by vasopressin involves phosphorylation and membrane translocation.Q43223386
Time course of renal Na-K-ATPase, NHE3, NKCC2, NCC, and ENaC abundance changes with dietary NaCl restrictionQ44129267
Sodium transporter abundance profiling in kidney: effect of spironolactoneQ44174210
Angiotensin II clamp prevents the second step in renal apical NHE3 internalization during acute hypertensionQ44174268
Upregulation of Na+ transporter abundances in response to chronic thiazide or loop diuretic treatment in ratsQ44185763
Effects of dietary fat, NaCl, and fructose on renal sodium and water transporter abundances and systemic blood pressureQ45013697
Altered renal distal tubule structure and renal Na(+) and Ca(2+) handling in a mouse model for Gitelman's syndrome.Q45038689
Molecular weight estimation of membrane bound ATPase by in vacuo radiation inactivationQ46602188
ANG II provokes acute trafficking of distal tubule Na+-Cl(-) cotransporter to apical membraneQ46774246
The verdict from ALLHAT--thiazide diuretics are the preferred initial therapy for hypertensionQ78651065
Redistribution of distal tubule Na+-Cl- cotransporter (NCC) in response to a high-salt dietQ28564280
Effects of dietary salt on renal Na+ transporter subcellular distribution, abundance, and phosphorylation statusQ28583444
WNK kinases regulate thiazide-sensitive Na-Cl cotransportQ28584824
A SPAK isoform switch modulates renal salt transport and blood pressureQ28586855
Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosteroneQ28592337
Claudin-2 forms homodimers and is a component of a high molecular weight protein complexQ30428439
Effects of ACE inhibition on proximal tubule sodium transportQ33226444
Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilliQ33589114
Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressureQ33784369
Mammalian distal tubule: physiology, pathophysiology, and molecular anatomyQ33807213
The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of miceQ33815744
Lipid rafts: elusive or illusive?Q33973937
Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidneyQ34016466
Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertensionQ34241490
SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstrictionQ34457030
Apoptosis-associated tyrosine kinase scaffolding of protein phosphatase 1 and SPAK reveals a novel pathway for Na-K-2C1 cotransporter regulationQ34608164
γ-Adducin stimulates the thiazide-sensitive NaCl cotransporterQ34695392
Intratubular renin-angiotensin system in hypertensionQ34777649
Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndromeQ35409776
Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertensionQ35421933
Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent processQ35974133
Renal expression of parvalbumin is critical for NaCl handling and response to diureticsQ35990289
Role of the WNK-activated SPAK kinase in regulating blood pressureQ36039159
Regulation of diverse ion transport pathways by WNK4 kinase: a novel molecular switchQ36088720
Lipid rafts, detergent-resistant membranes, and raft targeting signalsQ36659985
Surface expression of epithelial Na channel protein in rat kidneyQ36667908
Renal Na+-K+-Cl- cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent.Q36877776
LC-MS/MS analysis of differential centrifugation fractions from native inner medullary collecting duct of ratQ37018481
Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesiclesQ37162333
Renal NHE3 and NaPi2 partition into distinct membrane domainsQ37162385
WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interactionQ37258483
Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1.Q37337316
Role of SPAK and OSR1 signalling in the regulation of NaCl cotransportersQ37879421
Exploring the intricate regulatory network controlling the thiazide-sensitive NaCl cotransporter (NCC).Q37934598
P433issue2
P921main subjectphosphorylationQ242736
P304page(s)C147-63
P577publication date2012-10-31
P1433published inAmerican Journal of Physiology - Cell PhysiologyQ2227080
P1476titleEffects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties
P478volume304

Reverse relations

cites work (P2860)
Q39125105Cardiovascular benefits associated with higher dietary K+ vs. lower dietary Na+: evidence from population and mechanistic studies
Q49829887Consequences of SPAK inactivation on Hyperkalemic Hypertension caused by WNK1 mutations: evidence for differential roles of WNK1 and WNK4.
Q26827742Considerations when quantitating protein abundance by immunoblot
Q38307745Dietary potassium and the renal control of salt balance and blood pressure
Q37476592Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition
Q52975643Distal convoluted tubule.
Q38189985Electroneutral absorption of NaCl by the aldosterone-sensitive distal nephron: implication for normal electrolytes homeostasis and blood pressure regulation.
Q33568904Increasing plasma [K+] by intravenous potassium infusion reduces NCC phosphorylation and drives kaliuresis and natriuresis
Q37092421Maintaining Balance Under Pressure: Integrated Regulation of Renal Transporters During Hypertension
Q35274077Mechanisms of angiotensin II stimulation of NCC are time-dependent in mDCT15 cells
Q35094158Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2.
Q39137286Potassium Homeostasis: The Knowns, the Unknowns, and the Health Benefits
Q41643544Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension.
Q34174710Regulation of with-no-lysine kinase signaling by Kelch-like proteins
Q28397667Renal NCC is unchanged in the midpregnant rat and decreased in the late pregnant rat despite avid renal Na+ retention
Q35436934SPAK-mediated NCC regulation in response to low-K+ diet
Q36144496Short-term nonpressor angiotensin II infusion stimulates sodium transporters in proximal tubule and distal nephron.
Q36802752The absence of intrarenal ACE protects against hypertension
Q87333060The mineralocorticoid receptor (MR) regulates ENaC but not NCC in mice with random MR deletion
Q38757876The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate
Q41911751The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation
Q48148524Transcranial Doppler in autonomic testing: standards and clinical applications
Q34420520WNK4 is the major WNK positively regulating NCC in the mouse kidney

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