Individual Cardiac Mitochondria Undergo Rare Transient Permeability Transition Pore Openings

scientific article published on 28 December 2015

Individual Cardiac Mitochondria Undergo Rare Transient Permeability Transition Pore Openings is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1161/CIRCRESAHA.115.308093
P932PMC publication ID4779382
P698PubMed publication ID26712344

P50authorJeffery D. MolkentinQ54858774
Donald M. BersQ40664240
P2093author name stringXiyuan Lu
Jennifer Q Kwong
P2860cites workTransient opening of mitochondrial permeability transition pore by reactive oxygen species protects myocardium from ischemia-reperfusion injuryQ46129017
Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.Q52521095
Mitochondria Are Excitable Organelles Capable of Generating and Conveying Electrical and Calcium SignalsQ53967833
Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts.Q54039752
Mitochondrial reticulum for cellular energy distribution in muscleQ59059572
Calcium modulation of mitochondrial inner membrane channel activityQ67690549
Structural proximity of mitochondria to calcium release units in rat ventricular myocardium may suggest a role in Ca2+ sequestrationQ73287161
From ATP to PTP and Back: A Dual Function for the Mitochondrial ATP SynthaseQ27004110
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell deathQ28242653
The mitochondrial permeability transition pore: molecular nature and role as a target in cardioprotectionQ28248925
Dimers of mitochondrial ATP synthase form the permeability transition poreQ28287824
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell deathQ28297152
The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger siteQ28306067
Mitochondrial free calcium regulation during sarcoplasmic reticulum calcium release in rat cardiac myocytes.Q30487673
Kissing and nanotunneling mediate intermitochondrial communication in the heart.Q30536546
Fluctuations in mitochondrial membrane potential caused by repetitive gating of the permeability transition poreQ30785418
Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS releaseQ33913079
Mitochondrial dysfunction in cardiac disease: ischemia--reperfusion, aging, and heart failureQ33953515
Imaging the permeability pore transition in single mitochondriaQ34167671
The evolution of A-, F-, and V-type ATP synthases and ATPases: reversals in function and changes in the H+/ATP coupling ratioQ34357430
Exocytosis and endocytosis: modes, functions, and coupling mechanismsQ34657846
Protective role of transient pore openings in calcium handling by cardiac mitochondriaQ35266787
Distinct mPTP activation mechanisms in ischaemia-reperfusion: contributions of Ca2+, ROS, pH, and inorganic polyphosphateQ35555215
Dynamics of matrix-free Ca2+ in cardiac mitochondria: two components of Ca2+ uptake and role of phosphate bufferingQ35995723
Metabolic labeling reveals proteome dynamics of mouse mitochondriaQ36455704
Superoxide flashes in single mitochondriaQ36900957
Control of mitochondrial ATP synthesis in the heartQ37121254
The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS miceQ37261104
Mitochondria and reperfusion injury of the heart--a holey death but not beyond salvationQ37439453
The permeability transition pore as a Ca(2+) release channel: new answers to an old questionQ38003544
Perspectives on kiss-and-run: role in exocytosis, endocytosis, and neurotransmissionQ38067906
Physiologic functions of cyclophilin D and the mitochondrial permeability transition pore.Q38094017
Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membraneQ40615810
The inner mitochondrial membrane contains ion-conducting channels similar to those found in bacteria.Q44810762
Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protectionQ44832208
P433issue5
P304page(s)834-841
P577publication date2015-12-28
P1433published inCirculation ResearchQ2599020
P1476titleIndividual Cardiac Mitochondria Undergo Rare Transient Permeability Transition Pore Openings
P478volume118

Reverse relations

cites work (P2860)
Q57117291Bioenergetic Feedback between Heart Cell Contractile Machinery and Mitochondrial 3D Deformations
Q48061561Ca2+ binding to F-ATP synthase β subunit triggers the mitochondrial permeability transition
Q101222461Calcium influx through the mitochondrial calcium uniporter holocomplex, MCUcx
Q46742920Cyclophilin D regulates the dynamic assembly of mitochondrial ATP synthase into synthasomes.
Q97067070Cyclophilin D: An Integrator of Mitochondrial Function
Q90009702Dual dynamics of mitochondrial permeability transition pore opening
Q37699474Expert consensus document: Mitochondrial function as a therapeutic target in heart failure
Q99727712Hydrogen peroxide diffusion and scavenging shapes mitochondrial network instability and failure by sensitizing ROS-induced ROS release
Q92924523Imaging Mitochondrial Functions: from Fluorescent Dyes to Genetically-Encoded Sensors
Q39109413Ischemia/Reperfusion
Q38920740Mitochondrial Ca2+ and regulation of the permeability transition pore
Q95848133Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection
Q38807928New Roles for an Old Pore
Q45064238New and revisited approaches to preserving the reperfused myocardium
Q42370236On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells
Q40393419Rapid frequency-dependent changes in free mitochondrial calcium concentration in rat cardiac myocytes.
Q39637618Sex differences in the regulation of spatially distinct cardiac mitochondrial subpopulations
Q64251293Slow Ca Efflux by Ca/H Exchange in Cardiac Mitochondria Is Modulated by Ca Re-uptake via MCU, Extra-Mitochondrial pH, and H Pumping by FF-ATPase
Q91133678The machineries, regulation and cellular functions of mitochondrial calcium

Search more.