scholarly article | Q13442814 |
P50 | author | Bernd Fritzsch | Q30519140 |
P2093 | author name string | Kirk W Beisel | |
Laura A Hansen | |||
P2860 | cites work | Notch signalling pathway mediates hair cell development in mammalian cochlea | Q22009040 |
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells | Q22251095 | ||
Core transcriptional regulatory circuitry in human embryonic stem cells | Q24322016 | ||
Essential role of retinoblastoma protein in mammalian hair cell development and hearing | Q24545148 | ||
Brn3c null mutant mice show long-term, incomplete retention of some afferent inner ear innervation | Q24798672 | ||
The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear | Q25256767 | ||
Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation | Q28117650 | ||
Fringe is a glycosyltransferase that modifies Notch | Q28143123 | ||
Autoregulation of neurogenesis by GDF11 | Q28204949 | ||
Characterization of epidermal neural crest stem cell (EPI-NCSC) grafts in the lesioned spinal cord | Q28235566 | ||
The conserved WRPW motif of Hes6 mediates proteasomal degradation | Q28250967 | ||
Smad transcription factors | Q28284775 | ||
Inhibitors of differentiation and DNA binding (Ids) regulate Math1 and hair cell formation during the development of the organ of Corti | Q28506556 | ||
FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis | Q28506828 | ||
Identification of cis-element regulating expression of the mouse Fgf10 gene during inner ear development | Q28506880 | ||
Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function | Q47073232 | ||
Phylogenetic profiling of protein interaction networks in eukaryotic transcription factors reveals focal proteins being ancestral to hubs | Q47285873 | ||
Neuroscience. No more cortical neurons for you. | Q48444319 | ||
p27(Kip1) deficiency causes organ of Corti pathology and hearing loss | Q48630140 | ||
Mash1 and Ngn1 control distinct steps of determination and differentiation in the olfactory sensory neuron lineage. | Q48638602 | ||
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. | Q49042849 | ||
Generation of inner ear cell types from embryonic stem cells | Q50463285 | ||
Pluripotent stem cells from the adult mouse inner ear. | Q50482567 | ||
A morphogenetic wave of p27Kip1 transcription directs cell cycle exit during organ of Corti development | Q52014319 | ||
Expression of mouse Foxi class genes in early craniofacial development | Q52087464 | ||
Expression of BMP signalling pathway members in the developing zebrafish inner ear and lateral line | Q52129042 | ||
Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation | Q52165453 | ||
Functional conservation of atonal and Math1 in the CNS and PNS. | Q52171174 | ||
Dynamics of placodal lineage development revealed by targeted transgene expression | Q52175628 | ||
Development of the Mouse Inner Ear and Origin of Its Sensory Organs | Q52188228 | ||
Disrupted development of the cerebral hemispheres in transgenic mice expressing the mammalian Groucho homologue transducin-like-enhancer of split 1 in postmitotic neurons | Q52538980 | ||
Clonal analysis of the relationships between mechanosensory cells and the neurons that innervate them in the chicken ear | Q57375185 | ||
A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea | Q73849637 | ||
Pluripotent neural crest stem cells in the adult hair follicle | Q80560251 | ||
Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition | Q81123229 | ||
Wnt signals mediate a fate decision between otic placode and epidermis | Q82444199 | ||
Atoh1 null mice show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retention | Q28508345 | ||
Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes | Q28508554 | ||
Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d | Q28508628 | ||
Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear | Q28510001 | ||
The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear. | Q28510277 | ||
Pax2 contributes to inner ear patterning and optic nerve trajectory | Q28511597 | ||
Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis | Q28511665 | ||
GATA-3: an unexpected regulator of cell lineage determination in skin | Q28512924 | ||
Math1: an essential gene for the generation of inner ear hair cells | Q28513764 | ||
Identification of neurogenin, a vertebrate neuronal determination gene | Q28564456 | ||
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti | Q28585281 | ||
Transcription factor GATA-3 alters pathway selection of olivocochlear neurons and affects morphogenesis of the ear | Q28585452 | ||
Sox2 is required for sensory organ development in the mammalian inner ear | Q28585583 | ||
Fgf3 and Fgf10 are required for mouse otic placode induction | Q28585848 | ||
Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit | Q28585974 | ||
Foxg1 is required for morphogenesis and histogenesis of the mammalian inner ear | Q28589083 | ||
The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles | Q28589170 | ||
Antagonistic effects of Grg6 and Groucho/TLE on the transcription repression activity of brain factor 1/FoxG1 and cortical neuron differentiation | Q28590799 | ||
Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh. | Q28591489 | ||
Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear | Q28592816 | ||
Suppression of neural fate and control of inner ear morphogenesis by Tbx1 | Q28593065 | ||
Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse | Q28593114 | ||
Specification of the mammalian cochlea is dependent on Sonic hedgehog | Q28593205 | ||
FGF8 initiates inner ear induction in chick and mouse | Q28593974 | ||
NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development | Q28594435 | ||
Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems | Q29026493 | ||
neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia | Q29615041 | ||
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing | Q29615155 | ||
Proneural genes and the specification of neural cell types | Q29616807 | ||
Spiral ganglion neurons are protected from degeneration by GDNF gene therapy. | Q30473538 | ||
Neurogenin 1 null mutant ears develop fewer, morphologically normal hair cells in smaller sensory epithelia devoid of innervation | Q30473551 | ||
Groucho-Dependent and -Independent Repression Activities of Runt Domain Proteins | Q36572515 | ||
Lhx2 maintains stem cell character in hair follicles | Q36688765 | ||
Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant mice | Q36824504 | ||
Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression | Q37260484 | ||
Expression and function of FGF10 in mammalian inner ear development | Q37524712 | ||
Molecular profiling reveals synaptic release machinery in Merkel cells. | Q37569634 | ||
Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene | Q38338927 | ||
Expression of mouse fibroblast growth factor and fibroblast growth factor receptor genes during early inner ear development | Q38451515 | ||
Regeneration of human auditory nerve. In vitro/in video demonstration of neural progenitor cells in adult human and guinea pig spiral ganglion | Q40430449 | ||
Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation. | Q40456713 | ||
TGF-beta control of rat thyroid follicular cells differentiation | Q40634896 | ||
Spiel-ohne-grenzen/pou2 mediates regional competence to respond to Fgf8 during zebrafish early neural development. | Q40657976 | ||
Physical and Functional Interaction between GATA-3 and Smad3 Allows TGF-β Regulation of GATA Target Genes | Q40757292 | ||
Phosphorylation inhibits the DNA-binding activity of MyoD homodimers but not MyoD-E12 heterodimers | Q41514162 | ||
BMPs inhibit neurogenesis by a mechanism involving degradation of a transcription factor | Q41646190 | ||
MicroRNA gene expression in the mouse inner ear. | Q46189877 | ||
A bHLH transcriptional network regulating the specification of retinal ganglion cells | Q46633565 | ||
Molecular signals regulating proliferation of stem and progenitor cells in mouse olfactory epithelium | Q46660110 | ||
Progenitor cells of the olfactory receptor neuron lineage | Q46695680 | ||
Sonic hedgehog promotes mouse inner ear progenitor cell proliferation and hair cell generation in vitro | Q46890781 | ||
Influence of supporting cells on neuronal degeneration after hair cell loss | Q30492612 | ||
Clinical application of neurotrophic factors: the potential for primary auditory neuron protection | Q30499419 | ||
Towards a molecular understanding of Drosophila hearing | Q30500469 | ||
Inhibition of neurogenesis at the zebrafish midbrain-hindbrain boundary by the combined and dose-dependent activity of a new hairy/E(spl) gene pair | Q30978210 | ||
Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons | Q31001528 | ||
Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear. | Q33607542 | ||
A genetic programme for neuronal connectivity | Q33899449 | ||
Developmental evolutionary biology of the vertebrate ear: conserving mechanoelectric transduction and developmental pathways in diverging morphologies | Q34105118 | ||
Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma | Q34147557 | ||
Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner ear | Q34154079 | ||
Neural crest origin of mammalian Merkel cells. | Q34184663 | ||
Convergent evolution of gene networks by single-gene duplications in higher eukaryotes | Q34299183 | ||
Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals | Q34394494 | ||
Evolution and development of the vertebrate ear. | Q34397952 | ||
Visualization of embryonic neural stem cells using Hes promoters in transgenic mice. | Q34458175 | ||
Revisiting cell fate specification in the inner ear. | Q34542008 | ||
Development and evolution of inner ear sensory epithelia and their innervation. | Q34968700 | ||
Early steps in the formation of neural tissue in ascidian embryos. | Q35026080 | ||
The basic helix-loop-helix protein family: comparative genomics and phylogenetic analysis | Q35032269 | ||
Molecular conservation and novelties in vertebrate ear development | Q35607378 | ||
Neurotrophins in the ear: their roles in sensory neuron survival and fiber guidance | Q35618353 | ||
Stem cells as therapy for hearing loss | Q35830658 | ||
Drug delivery to the inner ear using gene therapy. | Q35912971 | ||
Identification and molecular regulation of neural stem cells in the olfactory epithelium. | Q36144872 | ||
Roles of bHLH genes in neural stem cell differentiation | Q36144904 | ||
Strategies to preserve or regenerate spiral ganglion neurons. | Q36256519 | ||
Notch signalling in vertebrate neural development | Q36374960 | ||
A tale of two signals: Wnt and Hedgehog in dentate neurogenesis | Q36376746 | ||
Transcriptional co-repressors of Runx2. | Q36379041 | ||
Role of miRNA and miRNA processing factors in development and disease | Q36539251 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1181-1193 | |
P577 | publication date | 2006-12-01 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | BioEssays | Q4914614 |
P1476 | title | The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration? | |
P478 | volume | 28 |
Q54601000 | A comparison of in vitro treatments for directing stem cells toward a sensory neural fate |
Q34141795 | A novel Atoh1 "self-terminating" mouse model reveals the necessity of proper Atoh1 level and duration for hair cell differentiation and viability |
Q38706405 | Advances in nano-based inner ear delivery systems for the treatment of sensorineural hearing loss |
Q30541094 | An in vitro model of developmental synaptogenesis using cocultures of human neural progenitors and cochlear explants |
Q34447088 | Artificial induction of Sox21 regulates sensory cell formation in the embryonic chicken inner ear |
Q80235066 | Auditory neurons make stereotyped wiring decisions before maturation of their targets |
Q26853178 | Beyond generalized hair cells: molecular cues for hair cell types |
Q64257528 | Bone morphogenetic proteins and inner ear development |
Q37065180 | Branchio-oto-renal syndrome (BOR): novel mutations in the EYA1 gene, and a review of the mutational genetics of BOR. |
Q28505263 | Canal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activity |
Q47073675 | Cell lineage analysis reveals three different progenitor pools for neurosensory elements in the otic vesicle. |
Q30459149 | Challenges for stem cells to functionally repair the damaged auditory nerve |
Q30500202 | Conditional deletion of N-Myc disrupts neurosensory and non-sensory development of the ear. |
Q30398554 | Connecting the ear to the brain: Molecular mechanisms of auditory circuit assembly |
Q34685536 | Continued expression of GATA3 is necessary for cochlear neurosensory development |
Q30443527 | Correct timing of proliferation and differentiation is necessary for normal inner ear development and auditory hair cell viability |
Q50352545 | Deterioration of the Medial Olivocochlear Efferent System Accelerates Age-Related Hearing Loss in Pax2-Isl1 Transgenic Mice. |
Q42575915 | Differential and overlapping expression pattern of SOX2 and SOX9 in inner ear development |
Q46751165 | Differentiation of inner ear stem cells to functional sensory neurons |
Q28744483 | Dissecting the molecular basis of organ of Corti development: Where are we now? |
Q30365215 | Distribution of neurosensory progenitor pools during inner ear morphogenesis unveiled by cell lineage reconstruction |
Q28659326 | Evolution of vertebrate mechanosensory hair cells and inner ears: toward identifying stimuli that select mutation driven altered morphologies. |
Q28754792 | Evolutionary insights into the unique electromotility motor of mammalian outer hair cells. |
Q30394636 | Evolving gene regulatory networks into cellular networks guiding adaptive behavior: an outline how single cells could have evolved into a centralized neurosensory system |
Q37294806 | Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear. |
Q43507552 | Fgf10 expression patterns in the developing chick inner ear |
Q92658231 | GSK3 regulates hair cell fate in the developing mammalian cochlea |
Q47864535 | Gene, cell, and organ multiplication drives inner ear evolution |
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Q35097530 | HMGA2, the architectural transcription factor high mobility group, is expressed in the developing and mature mouse cochlea |
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Q36372589 | Insm1 promotes neurogenic proliferation in delaminated otic progenitors |
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Q30475885 | Localized cell and drug delivery for auditory prostheses. |
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