The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration?

scientific article published on December 2006

The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/BIES.20502
P932PMC publication ID3901523
P698PubMed publication ID17120192

P50authorBernd FritzschQ30519140
P2093author name stringKirk W Beisel
Laura A Hansen
P2860cites workNotch signalling pathway mediates hair cell development in mammalian cochleaQ22009040
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cellsQ22251095
Core transcriptional regulatory circuitry in human embryonic stem cellsQ24322016
Essential role of retinoblastoma protein in mammalian hair cell development and hearingQ24545148
Brn3c null mutant mice show long-term, incomplete retention of some afferent inner ear innervationQ24798672
The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner earQ25256767
Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferationQ28117650
Fringe is a glycosyltransferase that modifies NotchQ28143123
Autoregulation of neurogenesis by GDF11Q28204949
Characterization of epidermal neural crest stem cell (EPI-NCSC) grafts in the lesioned spinal cordQ28235566
The conserved WRPW motif of Hes6 mediates proteasomal degradationQ28250967
Smad transcription factorsQ28284775
Inhibitors of differentiation and DNA binding (Ids) regulate Math1 and hair cell formation during the development of the organ of CortiQ28506556
FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesisQ28506828
Identification of cis-element regulating expression of the mouse Fgf10 gene during inner ear developmentQ28506880
Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) functionQ47073232
Phylogenetic profiling of protein interaction networks in eukaryotic transcription factors reveals focal proteins being ancestral to hubsQ47285873
Neuroscience. No more cortical neurons for you.Q48444319
p27(Kip1) deficiency causes organ of Corti pathology and hearing lossQ48630140
Mash1 and Ngn1 control distinct steps of determination and differentiation in the olfactory sensory neuron lineage.Q48638602
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.Q49042849
Generation of inner ear cell types from embryonic stem cellsQ50463285
Pluripotent stem cells from the adult mouse inner ear.Q50482567
A morphogenetic wave of p27Kip1 transcription directs cell cycle exit during organ of Corti developmentQ52014319
Expression of mouse Foxi class genes in early craniofacial developmentQ52087464
Expression of BMP signalling pathway members in the developing zebrafish inner ear and lateral lineQ52129042
Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiationQ52165453
Functional conservation of atonal and Math1 in the CNS and PNS.Q52171174
Dynamics of placodal lineage development revealed by targeted transgene expressionQ52175628
Development of the Mouse Inner Ear and Origin of Its Sensory OrgansQ52188228
Disrupted development of the cerebral hemispheres in transgenic mice expressing the mammalian Groucho homologue transducin-like-enhancer of split 1 in postmitotic neuronsQ52538980
Clonal analysis of the relationships between mechanosensory cells and the neurons that innervate them in the chicken earQ57375185
A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochleaQ73849637
Pluripotent neural crest stem cells in the adult hair follicleQ80560251
Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibitionQ81123229
Wnt signals mediate a fate decision between otic placode and epidermisQ82444199
Atoh1 null mice show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retentionQ28508345
Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodesQ28508554
Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4dQ28508628
Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner earQ28510001
The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.Q28510277
Pax2 contributes to inner ear patterning and optic nerve trajectoryQ28511597
Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosisQ28511665
GATA-3: an unexpected regulator of cell lineage determination in skinQ28512924
Math1: an essential gene for the generation of inner ear hair cellsQ28513764
Identification of neurogenin, a vertebrate neuronal determination geneQ28564456
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of CortiQ28585281
Transcription factor GATA-3 alters pathway selection of olivocochlear neurons and affects morphogenesis of the earQ28585452
Sox2 is required for sensory organ development in the mammalian inner earQ28585583
Fgf3 and Fgf10 are required for mouse otic placode inductionQ28585848
Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exitQ28585974
Foxg1 is required for morphogenesis and histogenesis of the mammalian inner earQ28589083
The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair folliclesQ28589170
Antagonistic effects of Grg6 and Groucho/TLE on the transcription repression activity of brain factor 1/FoxG1 and cortical neuron differentiationQ28590799
Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh.Q28591489
Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner earQ28592816
Suppression of neural fate and control of inner ear morphogenesis by Tbx1Q28593065
Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouseQ28593114
Specification of the mammalian cochlea is dependent on Sonic hedgehogQ28593205
FGF8 initiates inner ear induction in chick and mouseQ28593974
NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during developmentQ28594435
Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systemsQ29026493
neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory gangliaQ29615041
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageingQ29615155
Proneural genes and the specification of neural cell typesQ29616807
Spiral ganglion neurons are protected from degeneration by GDNF gene therapy.Q30473538
Neurogenin 1 null mutant ears develop fewer, morphologically normal hair cells in smaller sensory epithelia devoid of innervationQ30473551
Groucho-Dependent and -Independent Repression Activities of Runt Domain ProteinsQ36572515
Lhx2 maintains stem cell character in hair folliclesQ36688765
Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant miceQ36824504
Spatial shaping of cochlear innervation by temporally regulated neurotrophin expressionQ37260484
Expression and function of FGF10 in mammalian inner ear developmentQ37524712
Molecular profiling reveals synaptic release machinery in Merkel cells.Q37569634
Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness geneQ38338927
Expression of mouse fibroblast growth factor and fibroblast growth factor receptor genes during early inner ear developmentQ38451515
Regeneration of human auditory nerve. In vitro/in video demonstration of neural progenitor cells in adult human and guinea pig spiral ganglionQ40430449
Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation.Q40456713
TGF-beta control of rat thyroid follicular cells differentiationQ40634896
Spiel-ohne-grenzen/pou2 mediates regional competence to respond to Fgf8 during zebrafish early neural development.Q40657976
Physical and Functional Interaction between GATA-3 and Smad3 Allows TGF-β Regulation of GATA Target GenesQ40757292
Phosphorylation inhibits the DNA-binding activity of MyoD homodimers but not MyoD-E12 heterodimersQ41514162
BMPs inhibit neurogenesis by a mechanism involving degradation of a transcription factorQ41646190
MicroRNA gene expression in the mouse inner ear.Q46189877
A bHLH transcriptional network regulating the specification of retinal ganglion cellsQ46633565
Molecular signals regulating proliferation of stem and progenitor cells in mouse olfactory epitheliumQ46660110
Progenitor cells of the olfactory receptor neuron lineageQ46695680
Sonic hedgehog promotes mouse inner ear progenitor cell proliferation and hair cell generation in vitroQ46890781
Influence of supporting cells on neuronal degeneration after hair cell lossQ30492612
Clinical application of neurotrophic factors: the potential for primary auditory neuron protectionQ30499419
Towards a molecular understanding of Drosophila hearingQ30500469
Inhibition of neurogenesis at the zebrafish midbrain-hindbrain boundary by the combined and dose-dependent activity of a new hairy/E(spl) gene pairQ30978210
Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneuronsQ31001528
Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear.Q33607542
A genetic programme for neuronal connectivityQ33899449
Developmental evolutionary biology of the vertebrate ear: conserving mechanoelectric transduction and developmental pathways in diverging morphologiesQ34105118
Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinomaQ34147557
Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner earQ34154079
Neural crest origin of mammalian Merkel cells.Q34184663
Convergent evolution of gene networks by single-gene duplications in higher eukaryotesQ34299183
Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammalsQ34394494
Evolution and development of the vertebrate ear.Q34397952
Visualization of embryonic neural stem cells using Hes promoters in transgenic mice.Q34458175
Revisiting cell fate specification in the inner ear.Q34542008
Development and evolution of inner ear sensory epithelia and their innervation.Q34968700
Early steps in the formation of neural tissue in ascidian embryos.Q35026080
The basic helix-loop-helix protein family: comparative genomics and phylogenetic analysisQ35032269
Molecular conservation and novelties in vertebrate ear developmentQ35607378
Neurotrophins in the ear: their roles in sensory neuron survival and fiber guidanceQ35618353
Stem cells as therapy for hearing lossQ35830658
Drug delivery to the inner ear using gene therapy.Q35912971
Identification and molecular regulation of neural stem cells in the olfactory epithelium.Q36144872
Roles of bHLH genes in neural stem cell differentiationQ36144904
Strategies to preserve or regenerate spiral ganglion neurons.Q36256519
Notch signalling in vertebrate neural developmentQ36374960
A tale of two signals: Wnt and Hedgehog in dentate neurogenesisQ36376746
Transcriptional co-repressors of Runx2.Q36379041
Role of miRNA and miRNA processing factors in development and diseaseQ36539251
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)1181-1193
P577publication date2006-12-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inBioEssaysQ4914614
P1476titleThe molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration?
P478volume28

Reverse relations

cites work (P2860)
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