Proneural genes and the specification of neural cell types

scientific article (publication date: July 2002)

Proneural genes and the specification of neural cell types is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1001322387
P356DOI10.1038/NRN874
P3181OpenCitations bibliographic resource ID1440800
P698PubMed publication ID12094208
P5875ResearchGate publication ID11282008

P2093author name stringBertrand N
Castro DS
Guillemot F
P2860cites workSynergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300Q22009398
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteinsQ24299387
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequenceQ24300878
Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesisQ24314479
Helix-loop-helix proteins: regulators of transcription in eucaryotic organismsQ24554353
NeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin geneQ24644235
Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identityQ24672666
Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activationQ27731319
Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domainQ27732150
Notch signaling: cell fate control and signal integration in developmentQ27861061
Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fateQ28200195
Id and developmentQ28200725
Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanismsQ28203690
Transformation of sensory organ identity by ectopic expression of Cut in DrosophilaQ46061518
Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaeteQ46252846
The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2.Q46381166
atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brainQ47072663
The proneural gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous systemQ47072715
Correct coordination of neuronal differentiation events in ventral forebrain requires the bHLH factor MASH1.Q47622357
Wingless and Notch regulate cell-cycle arrest in the developing Drosophila wingQ47842311
amos, a proneural gene for Drosophila olfactory sense organs that is regulated by lozengeQ47879297
Functional properties of the neuronal nicotinic acetylcholine receptor beta3 promoter in the developing central nervous systemQ48010400
cash4, a novel achaete-scute homolog induced by Hensen's node during generation of the posterior nervous systemQ48052959
X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiationQ48056539
The achaete-scute gene complex of D. melanogaster: conserved domains in a subset of genes required for neurogenesis and their homology to myc.Q48341121
Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2.Q48341848
Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons.Q48341860
Math1 is essential for genesis of cerebellar granule neurons.Q48594976
XATH-1, a vertebrate homolog of Drosophila atonal, induces a neuronal differentiation within ectodermal progenitors.Q48671276
Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells.Q48692503
Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.Q48829693
Proprioceptor pathway development is dependent on Math1.Q48854506
NeuroD2 is necessary for development and survival of central nervous system neurons.Q48878307
Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors.Q48959930
XCoe2, a transcription factor of the Col/Olf-1/EBF family involved in the specification of primary neurons in Xenopus.Q51098860
Defective neuroblast commitment in mutants of the achaete-scute complex and adjacent genes of D. melanogaster.Q51167386
Interactions between chip and the achaete/scute-daughterless heterodimers are required for pannier-driven proneural patterning.Q51603879
Specification of the central noradrenergic phenotype by the homeobox gene Phox2b.Q52169701
Notch signalling and the control of cell fate choices in vertebrates.Q52180338
The specificity of proneural genes in determining Drosophila sense organ identity.Q52183485
Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing.Q52236630
Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation.Q52541748
Sense organ identity in the Drosophila antenna is specified by the expression of the proneural gene atonal.Q52584240
The achaete-scute complex proneural genes contribute to neural precursor specification in the Drosophila CNSQ71527273
Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cellsQ73211895
Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous systemQ73555176
Crossregulation between Neurogenin2 and pathways specifying neuronal identity in the spinal cordQ74363242
Crystal structure of transcription factor E47: E-box recognition by a basic region helix-loop-helix dimerQ28238671
MASH1 maintains competence for BMP2-induced neuronal differentiation in post-migratory neural crest cellsQ28241846
Requirement for math5 in the development of retinal ganglion cellsQ28345916
The homeobox gene Phox2b is essential for the development of autonomic neural crest derivativesQ28505510
Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tubeQ28507554
Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsyQ28510873
The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cellsQ28512414
Math1: an essential gene for the generation of inner ear hair cellsQ28513764
Identification of neurogenin, a vertebrate neuronal determination geneQ28564456
A role for the helix-loop-helix protein Id2 in the control of oligodendrocyte developmentQ28579332
NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampusQ28584879
The cellular function of MASH1 in autonomic neurogenesisQ28589526
Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampusQ28591504
Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous systemQ28591759
Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factorsQ28592141
Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connectionQ28594759
neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory gangliaQ29615041
The MyoD family and myogenesis: redundancy, networks, and thresholdsQ29618503
Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix proteinQ29618504
Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neuronsQ29618538
Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fateQ29619008
Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneuronsQ31001528
Transcriptional control of neurotransmitter phenotypeQ33540096
The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fatesQ33540123
Vertebrate bHLH genes and the determination of neuronal fatesQ33786849
Determination of vertebrate retinal progenitor cell fate by the Notch pathway and basic helix-loop-helix transcription factorsQ33892192
cato encodes a basic helix-loop-helix transcription factor implicated in the correct differentiation of Drosophila sense organsQ33898738
Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in DrosophilaQ33916848
Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3.Q33926140
Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.Q33963287
The development of neural stem cellsQ34100159
Neuronal potential and lineage determination by neural stem cellsQ34100746
Emc, a negative HLH regulator with multiple functions in Drosophila developmentQ34113716
Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc.Q34114091
Cell cycle and cell fate in the nervous system.Q34141459
From DNA to form: the achaete-scute complexQ34172539
A turn of the helix: preventing the glial fateQ34217768
Stem cells and pattern formation in the nervous system: the possible versus the actualQ34245281
Lateral inhibition mediated by the Drosophila neurogenic gene delta is enhanced by proneural proteins.Q34324278
HLH proteins, fly neurogenesis, and vertebrate myogenesisQ34345733
atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous systemQ34350799
Hematopoietic development: a balancing act.Q34353104
Ventral neurogenesis and the neuron-glial switch.Q34376831
Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genesQ34407350
Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors.Q34409850
Molecular analysis of the asense gene, a member of the achaete-scute complex of Drosophila melanogaster, and its novel role in optic lobe development.Q34433098
The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons.Q34463715
Progression from extrinsic to intrinsic signaling in cell fate specification: a view from the nervous systemQ34492474
Neurogenesis in embryos and in adult neural stem cells.Q34516002
Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterningQ34526571
Specification of catecholaminergic and serotonergic neurons.Q34718055
The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 geneQ35114173
Neurogenin1 and neurogenin2 control two distinct waves of neurogenesis in developing dorsal root gangliaQ35200638
Patterning of the Drosophila nervous system: the achaete-scute gene complexQ35668488
BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesisQ35900138
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factorQ36706855
Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expressionQ36772826
X-ngnr-1 and Xath3 promote ectopic expression of sensory neuron markers in the neurula ectoderm and have distinct inducing properties in the retina.Q36779023
DNA binding and transcriptional regulatory activity of mammalian achaete-scute homologous (MASH) proteins revealed by interaction with a muscle-specific enhancerQ36964316
A genomewide survey of basic helix-loop-helix factors in DrosophilaQ37246430
The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genesQ38312146
Proneural gene self-stimulation in neural precursors: an essential mechanism for sense organ development that is regulated by Notch signalingQ40444854
Genetic control of cell fate specification in Drosophila peripheral nervous systemQ40614023
Neural fate specification in DrosophilaQ40780846
Xath5 participates in a network of bHLH genes in the developing Xenopus retinaQ41077886
Basic helix-loop-helix genes in neural developmentQ41353305
Acquisition of myogenic specificity by replacement of three amino acid residues from MyoD into E12Q41624448
BMPs inhibit neurogenesis by a mechanism involving degradation of a transcription factorQ41646190
Helix-loop-helix factors in growth and differentiation of the vertebrate nervous systemQ41655734
Activation of Xenopus genes required for lateral inhibition and neuronal differentiation during primary neurogenesisQ41706007
New members of the Drosophila Myc transcription factor subfamily revealed by a genome-wide examination for basic helix-loop-helix genesQ42652006
Two domains of MyoD mediate transcriptional activation of genes in repressive chromatin: a mechanism for lineage determination in myogenesisQ42803715
Retinal ganglion cell genesis requires lakritz, a Zebrafish atonal Homolog.Q43656760
Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signalingQ45243171
Spatial regulation of proneural gene activity: auto- and cross-activation of achaete is antagonized by extramacrochaetaeQ45978313
Atonal is the proneural gene for Drosophila photoreceptors.Q45994865
The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification.Q46021705
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)517-30
P577publication date2002-07-01
P1433published inNature Reviews NeuroscienceQ2108225
P1476titleProneural genes and the specification of neural cell types
P478volume3

Reverse relations

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Q39373830Differences of molecular expression mechanisms among neural cell adhesion molecule 1, synaptophysin, and chromogranin A in lung cancer cells
Q51895822Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus.
Q39417469Differentiation and functional incorporation of embryonic stem cell-derived GABAergic interneurons in the dentate gyrus of mice with temporal lobe epilepsy.
Q54413661Diffusible, membrane-bound, and extracellular matrix factors from olfactory ensheathing cells have different effects on the self-renewing and differentiating properties of neural stem cells
Q38782201Direct Conversion of Somatic Cells into Induced Neurons
Q64118644Direct Neuronal Reprogramming Reveals Unknown Functions for Known Transcription Factors
Q55426574Direct Reprogramming of Adult Human Somatic Stem Cells Into Functional Neurons Using Sox2, Ascl1, and Neurog2.
Q41946758Direct control of the proneural gene atonal by retinal determination factors during Drosophila eye development
Q34224069Direct lineage conversions: unnatural but useful?
Q34002389Direct transcriptional induction of Gadd45gamma by Ascl1 during neuronal differentiation
Q35788278Discrete regulatory regions control early and late expression of D-Pax2 during external sensory organ development
Q35581580Discriminative prediction of mammalian enhancers from DNA sequence.
Q28744483Dissecting the molecular basis of organ of Corti development: Where are we now?
Q47270973Distinct regulation of atonal in a visual organ of Drosophila: Organ-specific enhancer and lack of autoregulation in the larval eye.
Q42770363Distribution and function of splash, an achaete-scute homolog in the adult olfactory organ of the Caribbean spiny lobster Panulirus argus
Q42160001Drosophila Tufted Is a Gain-of-Function Allele of the Proneural Gene amos
Q42052525Dual role for Drosophila lethal of scute in CNS midline precursor formation and dopaminergic neuron and motoneuron cell fate
Q47343860Dual roles of Akirin2 protein during Xenopus neural development
Q28507651Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate
Q38213653Dynamic expression and roles of Hes factors in neural development.
Q41613816Dynamic expression of Notch-dependent neurogenic markers in the chick embryonic nervous system.
Q42095386Dynamic expression of notch signaling genes in neural stem/progenitor cells
Q37174231Dynamic signaling for neural stem cell fate determination
Q52693003Dysregulation of NEUROG2 plays a key role in focal cortical dysplasia.
Q58789236E proteins sharpen neurogenesis by modulating proneural bHLH transcription factors' activity in an E-box-dependent manner
Q34762158E-proteins orchestrate the progression of neural stem cell differentiation in the postnatal forebrain
Q37010255E2A proteins promote development of lymphoid-primed multipotent progenitors
Q80825060Early neuronal and glial fate restriction of embryonic neural stem cells
Q42523391Early teleostean basal ganglia development visualized by zebrafish Dlx2a, Lhx6, Lhx7, Tbr2 (eomesa), and GAD67 gene expression
Q80005967Effects of follistatin overexpression on cell differentiation in the chick embryo retina
Q37769467Embryonic and adult neural stem cell research in China.
Q41759849Embryonic development of the nervous system in the planarian Schmidtea polychroa
Q41285172Epb41l5 competes with Delta as a substrate for Mib1 to coordinate specification and differentiation of neurons.
Q34985447Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal
Q35063181Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains
Q37718005Epigenetic regulation of neurogenesis in the adult hippocampus
Q48283634Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains
Q95300622Estradiol-dependent axogenesis and Ngn3 expression are determined by XY sex chromosome complement in hypothalamic neurons
Q46087140Estrogen receptor subtype beta2 is involved in neuromast development in zebrafish (Danio rerio) larvae.
Q28078898Evidence-Based Theory for Integrated Genome Regulation of Ontogeny--An Unprecedented Role of Nuclear FGFR1 Signaling
Q37087574Evolution of cis-regulatory sequences in Drosophila
Q26778239Evolution of eumetazoan nervous systems: insights from cnidarians
Q38050350Evolution of sound and balance perception: innovations that aggregate single hair cells into the ear and transform a gravistatic sensor into the organ of corti
Q33688419Evolutionary changes in transcription factor coding sequence quantitatively alter sensory organ development and function
Q34381234Excitotoxic brain injury in adult zebrafish stimulates neurogenesis and long-distance neuronal integration
Q35193512Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments
Q34472095Expression at the imprinted dlk1-gtl2 locus is regulated by proneural genes in the developing telencephalon
Q52003127Expression of Hand2 is sufficient for neurogenesis and cell type-specific gene expression in the enteric nervous system.
Q34146480Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival
Q28506854Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression
Q48186496Expression of Sox2 in mature and immature teratomas of central nervous system
Q50075872Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers.
Q42468422Expression patterns of basic helix-loop-helix transcription factors define subsets of olfactory progenitor cells
Q38695143Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line
Q43250998Expression profiling upon Nex1/MATH-2-mediated neuritogenesis in PC12 cells and its implication in regeneration
Q92258271Extracellular Vesicle-Induced Differentiation of Neural Stem Progenitor Cells
Q34687169Extracellular signal-regulated kinase (ERK) 5 is necessary and sufficient to specify cortical neuronal fate
Q35111292Extremely low-frequency electromagnetic fields affect transcript levels of neuronal differentiation-related genes in embryonic neural stem cells
Q38289851Eya1 and Six1 promote neurogenesis in the cranial placodes in a SoxB1-dependent fashion
Q28277172Eye development and retinogenesis
Q51027250FGF signaling is required for determination of otic neuroblasts in the chick embryo.
Q40648767FGF-dependent Notch signaling maintains the spinal cord stem zone
Q42949135FGF-receptor signalling controls neural cell diversity in the zebrafish hindbrain by regulating olig2 and sox9.
Q36340752Fezf2 regulates multilineage neuronal differentiation through activating basic helix-loop-helix and homeodomain genes in the zebrafish ventral forebrain
Q44985592Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis
Q35378336Fgf16 is required for specification of GABAergic neurons and oligodendrocytes in the zebrafish forebrain
Q46779528Fgf19 regulated by Hh signaling is required for zebrafish forebrain development.
Q33884949Fluvoxamine stimulates oligodendrogenesis of cultured neural stem cells and attenuates inflammation and demyelination in an animal model of multiple sclerosis
Q36492340Forcing neural progenitor cells to cycle is insufficient to alter cell-fate decision and timing of neuronal differentiation in the spinal cord.
Q34539984From understanding the development landscape of the canonical fate-switch pair to constructing a dynamic landscape for two-step neural differentiation
Q35056615Function and regulation of Rnd proteins in cortical projection neuron migration
Q45036364Functional analysis of TCF4 missense mutations that cause Pitt-Hopkins syndrome.
Q38787528Functional characterization of the Japanese flounder (Paralichthys olivaceus) Sox2 gene promoter
Q50255242Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development.
Q41582256Functional distinctness of closely related transcription factors: a comparison of the Atonal and Amos proneural factors
Q48327450Functions of a jumonji-cyclin D1 pathway in the coordination of cell cycle exit and migration during neurogenesis in the mouse hindbrain
Q34126579GABA expression and regulation by sensory experience in the developing visual system
Q36090789GABAergic neuron specification in the spinal cord, the cerebellum, and the cochlear nucleus
Q42489960GABAergic specification in the basal forebrain is controlled by the LIM-hd factor Lhx7.
Q82948509GD2 expression is closely associated with neuronal differentiation of human umbilical cord blood-derived mesenchymal stem cells
Q48481509GSK3 temporally regulates neurogenin 2 proneural activity in the neocortex.
Q49158436Geminin regulates cortical progenitor proliferation and differentiation.
Q24531381Geminin regulates neuronal differentiation by antagonizing Brg1 activity
Q57785563Gene expression patterns determine the differential numbers of dorsocentral macrochaetes between M. domestica and D. melanogaster
Q39095805Generation of Cholinergic and Dopaminergic Interneurons from Human Pluripotent Stem Cells as a Relevant Tool for In Vitro Modeling of Neurological Disorders Pathology and Therapy.
Q33371076Generation of diverse neuronal subtypes in cloned populations of stem-like cells
Q26269984Generation of induced neuronal cells by the single reprogramming factor ASCL1
Q39208928Genetic fate mapping reveals that the caudal ganglionic eminence produces a large and diverse population of superficial cortical interneurons
Q37078121Genetic modification of neural stem cells
Q36529472Genetic networks controlling the development of midbrain dopaminergic neurons
Q34092990Genome-wide identification of cis-regulatory motifs and modules underlying gene coregulation using statistics and phylogeny
Q35905054Gfi/Pag-3/senseless zinc finger proteins: a unifying theme?
Q35568678Glial Cells Generate Neurons—Master Control within CNS Regions: Developmental Perspectives on Neural Stem Cells
Q35752440Glial specification in the vertebrate neural tube
Q35133557Gliogenic and neurogenic progenitors of the subventricular zone: who are they, where did they come from, and where are they going?
Q40014299Group III metabotropic glutamate receptor activation suppresses self-replication of undifferentiated neocortical progenitor cells.
Q35607401Growth factors and early development of otic neurons: interactions between intrinsic and extrinsic signals
Q33769686HES6-1 and HES6-2 function through different mechanisms during neuronal differentiation
Q37490454HIV Tat Impairs Neurogenesis through Functioning As a Notch Ligand and Activation of Notch Signaling Pathway
Q28072498HMGA1-pseudogenes and cancer
Q97530299HOTAIRM1 regulates neuronal differentiation by modulating NEUROGENIN 2 and the downstream neurogenic cascade
Q28547369Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis
Q35167951Half a century of neural prepatterning: the story of a few bristles and many genes.
Q24658166Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus
Q55077658Hes1 inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc03540f.
Q50981435Hes1 is required for the development of pharyngeal organs and survival of neural crest-derived mesenchymal cells in pharyngeal arches.
Q40215489Hes6 inhibits astrocyte differentiation and promotes neurogenesis through different mechanisms.
Q34082939Hes6 is required for the neurogenic activity of neurogenin and NeuroD
Q36754389Heterochronic misexpression of Ascl1 in the Atoh7 retinal cell lineage blocks cell cycle exit
Q29871108Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons
Q46969538High glucose alters the expression of genes involved in proliferation and cell-fate specification of embryonic neural stem cells
Q41993067Hox and senseless antagonism functions as a molecular switch to regulate EGF secretion in the Drosophila PNS.
Q41987343Huckebein-mediated autoregulation of Glide/Gcm triggers glia specification
Q92883429Human Cytomegalovirus Disruption of Calcium Signaling in Neural Progenitor Cells and Organoids
Q33258311Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes
Q33321958Human in vitro reporter model of neuronal development and early differentiation processes
Q42735883ID(ealizing) control of adult subventricular zone neural stem/precursor cell differentiation for CNS regeneration
Q51901190Id gene regulation and function in the prosensory domains of the chicken inner ear: a link between Bmp signaling and Atoh1.
Q24336565Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1
Q28593714Id2 is required for specification of dopaminergic neurons during adult olfactory neurogenesis
Q35996850Identification of Bombyx atonal and functional comparison with the Drosophila atonal proneural factor in the developing fly eye
Q46431829Identification of a conserved cis-regulatory element controlling mid-diencephalic expression of mouse Six3.
Q28593593Identification of a novel basic helix-loop-helix gene, Heslike, and its role in GABAergic neurogenesis
Q34206469Identification of a transient Sox5 expressing progenitor population in the neonatal ventral forebrain by a novel cis-regulatory element.
Q50055256Identification of neural transcription factors required for the differentiation of three neuronal subtypes in the sea urchin embryo.
Q38321926Identification of shared transcriptional targets for the proneural bHLH factors Xath5 and XNeuroD.
Q39909801Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons
Q37166985Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells
Q34487431Immature spinal cord neurons are dynamic regulators of adult nociceptive sensitivity
Q26829945Imprinted Zac1 in neural stem cells
Q44580781In vitro generation of early-born neurons from late retinal progenitors.
Q34602617In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development
Q51971580In vivo analysis of Ascl1 defined progenitors reveals distinct developmental dynamics during adult neurogenesis and gliogenesis.
Q35155364In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord
Q61806965Increased Anxiety-Related Behavior, Impaired Cognitive Function and Cellular Alterations in the Brain of Cend1-deficient Mice
Q36469493Induction and specification of cranial placodes
Q36100723Induction and specification of the vertebrate ectodermal placodes: precursors of the cranial sensory organs
Q37033287Induction of neuronal and tumor-related genes by adenovirus type 12 E1A.
Q53153031Induction of neuronal phenotypes from NG2+ glial progenitors by inhibiting epidermal growth factor receptor in mouse spinal cord injury.
Q43224792Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube
Q36740046Insights into neural stem cell biology from flies.
Q58694369Interaction between opposing modes of phospho-regulation of the proneural proteins Ascl1 and Ngn2
Q50480298Interhemispheric asymmetry of olfactory input-dependent neuronal specification in the adult brain.
Q38106711Intrinsic regulation of adult subventricular zone neural progenitor cells and the effect of brain injury
Q97568080Investigating cellular and molecular mechanisms of neurogenesis in Capitella teleta sheds light on the ancestor of Annelida
Q52087437Involvement of Hydra achaete-scute gene CnASH in the differentiation pathway of sensory neurons in the tentacles.
Q37699494JAK-STAT pathway activation in response to spinal cord injury in regenerative and non-regenerative stages of Xenopus laevis
Q41976049Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas
Q95660209KAT3-dependent acetylation of cell type-specific genes maintains neuronal identity in the adult mouse brain
Q47637255KDM3A-mediated demethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis
Q28769313Keeping sensory cells and evolving neurons to connect them to the brain: molecular conservation and novelties in vertebrate ear development
Q28593392Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways
Q34994221Knockdown of human TCF4 affects multiple signaling pathways involved in cell survival, epithelial to mesenchymal transition and neuronal differentiation
Q41260733LIN-32/Atonal Controls Oxygen Sensing Neuron Development in Caenorhabditis elegans
Q39528858LMO4 functions as a co-activator of neurogenin 2 in the developing cortex.
Q33533302Laser microdissection of sensory organ precursor cells of Drosophila microchaetes
Q35049107Lead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells.
Q50041523Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation.
Q35676676Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS.
Q40655872Linking specification to differentiation: From proneural genes to the regulation of ciliogenesis.
Q96348111Long-term association of a transcription factor with its chromatin binding site can stabilize gene expression and cell fate commitment
Q40126665Loss of ascl1a prevents secretory cell differentiation within the zebrafish intestinal epithelium resulting in a loss of distal intestinal motility
Q28084984Lost highway(s): barriers to postnatal cortical neurogenesis and implications for brain repair
Q64898599Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development.
Q37808164Maintenance and differentiation of neural stem cells
Q91925922Maintenance of active chromatin states by HMGN2 is required for stem cell identity in a pluripotent stem cell model
Q37783809Making senses development of vertebrate cranial placodes
Q24650452Mammalian Merkel cells are descended from the epidermal lineage
Q28511004Mash1 and Math3 are required for development of branchiomotor neurons and maintenance of neural progenitors
Q48932717Mash1 and neurogenin 2 enhance survival and differentiation of neural precursor cells after transplantation to rat brains via distinct modes of action.
Q34096351Mash1 efficiently reprograms rat astrocytes into neurons.
Q37605183Mash1 specifies neurons and oligodendrocytes in the postnatal brain
Q28677020Maternal-fetal unit interactions and eutherian neocortical development and evolution
Q28505011Math1 target genes are enriched with evolutionarily conserved clustered E-box binding sites
Q30481442Math5 expression and function in the central auditory system
Q58759716Matrin-3 is essential for fibroblast growth factor 2-dependent maintenance of neural stem cells
Q35992974Mechanisms and perspectives on differentiation of autonomic neurons
Q28507645Members of the miRNA-200 family regulate olfactory neurogenesis
Q48498090Mesodermal cell types induce neurogenesis from adult human hippocampal progenitor cells.
Q36271668Migration-related phenotypic divergence is associated with epigenetic modifications in rainbow trout
Q30513949Mitotic spindle orientation can direct cell fate and bias Notch activity in chick neural tube
Q51987359Mitotic spindle orientation distinguishes stem cell and terminal modes of neuron production in the early spinal cord.
Q33827953Modelling the Delta1/Notch1 pathway: in search of the mediator(s) of neural stem cell differentiation
Q26784059Molecular Biomarkers for Embryonic and Adult Neural Stem Cell and Neurogenesis
Q33251996Molecular characterization of retinal stem cells and their niches in adult zebrafish
Q35607378Molecular conservation and novelties in vertebrate ear development
Q26865469Molecular control of neurogenesis: a view from the mammalian cerebral cortex
Q35682080Molecular developmental neurobiology of formation, guidance and survival of primary vestibular neurons
Q28659308Molecular evolution of the vertebrate mechanosensory cell and ear
Q26822585Molecular roadblocks for cellular reprogramming
Q27313641Morphine Modulates Adult Neurogenesis and Contextual Memory by Impeding the Maturation of Neural Progenitors
Q26751190Morphogenetic and Histogenetic Roles of the Temporal-Spatial Organization of Cell Proliferation in the Vertebrate Corticogenesis as Revealed by Inter-specific Analyses of the Optic Tectum Cortex Development
Q100559556Motif 1 Binding Protein suppresses wingless to promote eye fate in Drosophila
Q42090137Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.
Q42078705Multi-site phospho-regulation of proneural transcription factors controls proliferation versus differentiation in development and reprogramming.
Q35827987Multi-site phosphorylation regulates NeuroD4 activity during primary neurogenesis: a conserved mechanism amongst proneural proteins
Q33263142Multiple enhancers contribute to spatial but not temporal complexity in the expression of the proneural gene, amos
Q28505437Multiple roles of Id4 in developmental myelination: predicted outcomes and unexpected findings
Q90110385Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas
Q35539865My what big eyes you have: how the Drosophila retina grows.
Q41481489MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis.
Q34731167Myosin VI reduces proliferation, but not differentiation, in pluripotent P19 cells
Q36710960Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation
Q42323235NEUROG2 drives cell cycle exit of neuronal precursors by specifically repressing a subset of cyclins acting at the G1 and S phases of the cell cycle.
Q27302358NF-kappaB/Rel-mediated regulation of the neural fate in Drosophila
Q42976906NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1.
Q34885587Naturally occurring Ngn2 promoter activators from Butea superba
Q35741939Nematostella vectensis achaete-scute homolog NvashA regulates embryonic ectodermal neurogenesis and represents an ancient component of the metazoan neural specification pathway
Q50658871Nemo promotes Notch-mediated lateral inhibition downstream of proneural factors.
Q38067378Neocortical arealization: evolution, mechanisms, and open questions
Q36402745Neural specification and differentiation
Q57280058Neural stem cell lineage-specific cannabinoid type-1 receptor regulates neurogenesis and plasticity in the adult mouse hippocampus
Q36449308Neural stem cell self-renewal
Q38636602Neural stem cells and neuro/gliogenesis in the central nervous system: understanding the structural and functional plasticity of the developing, mature, and diseased brain
Q37198942Neural stem cells secrete factors facilitating brain regeneration upon constitutive Raf-Erk activation
Q35101522NeuroD factors regulate cell fate and neurite stratification in the developing retina
Q41966306NeuroD regulates proliferation of photoreceptor progenitors in the retina of the zebrafish
Q30862451Neurodevelopment genes in lampreys reveal trends for forebrain evolution in craniates
Q39812863Neuroendocrine cancer-specific up-regulating mechanism of insulin-like growth factor binding protein-2 in small cell lung cancer.
Q37013649Neurogenesis continues in the third trimester of pregnancy and is suppressed by premature birth
Q48561591Neurogenesis in an annelid: characterization of brain neural precursors in the polychaete Capitella sp. I.
Q34579598Neurogenesis in the embryonic and adult brain: same regulators, different roles
Q39744827Neurogenesis in the water flea Daphnia magna (Crustacea, Branchiopoda) suggests different mechanisms of neuroblast formation in insects and crustaceans
Q27022400Neurogenesis in zebrafish - from embryo to adult
Q40010967Neurogenin 1 (Neurog1) expression in the ventral neural tube is mediated by a distinct enhancer and preferentially marks ventral interneuron lineages
Q81148667Neurogenin 1 mediates erythropoietin enhanced differentiation of adult neural progenitor cells
Q34806146Neurogenin 2 controls cortical neuron migration through regulation of Rnd2.
Q36008950Neurogenin 2 regulates progenitor cell-cycle progression and Purkinje cell dendritogenesis in cerebellar development.
Q53596578Neurogenin 3 and the enteroendocrine cell lineage in the adult mouse small intestinal epithelium.
Q28508842Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers
Q34597001Neurogenin1 is a determinant of zebrafish basal forebrain dopaminergic neurons and is regulated by the conserved zinc finger protein Tof/Fezl
Q39295423Neurogenin2 expression together with NeuroM regulates GDNF family neurotrophic factor receptor α1 (GFRα1) expression in the embryonic spinal cord
Q28590206Neurogenin2 specifies the connectivity of thalamic neurons by controlling axon responsiveness to intermediate target cues
Q41975539Neurogenin3 promotes early retinal neurogenesis
Q46026506Neurogenin3 restricts serotonergic neuron differentiation to the hindbrain.
Q40410529Neuronal fate determinants of adult olfactory bulb neurogenesis
Q48307745Neuronal lineage‐specific induction of phospholipase Cε expression in the developing mouse brain
Q33657155Neuronal regulation of the spatial patterning of neurogenesis
Q29616190Neuronal subtype specification in the cerebral cortex
Q35401982New insights into the Orange domain of E(spl)-M8, and the roles of the C-terminal domain in autoinhibition and Groucho recruitment
Q36361716New technologies, new findings, and new concepts in the study of vertebrate cis-regulatory sequences
Q33273085Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells
Q41960640Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei
Q52002201Noggin signaling from Xenopus animal blastomere lineages promotes a neural fate in neighboring vegetal blastomere lineages.
Q35104443Non-canonical Notch signaling represents an ancestral mechanism to regulate neural differentiation
Q90390334Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT
Q37607400Notch activity in the nervous system: to switch or not switch?
Q48617715Notch and NGF/p75NTR control dendrite morphology and the balance of excitatory/inhibitory synaptic input to hippocampal neurones through Neurogenin 3.
Q51958587Notch and suppressor of Hairless regulate levels but not patterns of Delta expression in Drosophila.
Q34080619Notch regulates the switch from symmetric to asymmetric neural stem cell division in the Drosophila optic lobe
Q27012660Notch signaling and proneural genes work together to control the neural building blocks for the initial scaffold in the hypothalamus
Q34341316Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina
Q36140085Notch signaling in the mammalian central nervous system: insights from mouse mutants
Q37331040Notch, neural stem cells, and brain tumors.
Q28246800Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord
Q39377533Notch: an interactive player in neurogenesis and disease
Q34393493Novel genes upregulated when NOTCH signalling is disrupted during hypothalamic development.
Q28508056Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo
Q35737574Old and new functions of proneural factors revealed by the genome-wide characterization of their transcriptional targets.
Q39623634Olig1 and ID4 interactions in living cells visualized by bimolecular fluorescence complementation technique
Q28288207Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome
Q48123752Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics
Q28593000Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells
Q53662277Olig2 directs astrocyte and oligodendrocyte formation in postnatal subventricular zone cells.
Q37421592On the mechanism underlying the divergent retinal and bristle defects of M8* (E(spl)D) in Drosophila.
Q37090002Origins of cortical GABAergic neurons in the cynomolgus monkey
Q22337303Origins of neurogenesis, a cnidarian view
Q51925405Oscillatory Notch-pathway activity in a delay model of neuronal differentiation.
Q42258504Oscillatory control of factors determining multipotency and fate in mouse neural progenitors
Q44612169Otx/otd homeobox genes specify distinct sensory neuron identities in C. elegans.
Q28505456Otx2 regulates subtype specification and neurogenesis in the midbrain
Q35760125Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways
Q33565484PRDM Proteins: Molecular Mechanisms in Signal Transduction and Transcriptional Regulation
Q35014013Parsing the prosencephalon
Q38068543Patterning and cell fate in the inner ear: a case for Notch in the chicken embryo
Q92185693Patterning via local cell-cell interactions in developing systems
Q51999112Pax2 regulates neuronal-glial cell fate choice in the embryonic optic nerve.
Q34541069Peripheral nerve injury induces adult brain neurogenesis and remodelling
Q41997216Persistent Gliosis Interferes with Neurogenesis in Organotypic Hippocampal Slice Cultures
Q41861495Phorbol-Ester Mediated Suppression of hASH1 Synthesis: Multiple Ways to Keep the Level Down
Q35397840Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2.
Q45247405Phylotypic expression of the bHLH genes Neurogenin2, Neurod, and Mash1 in the mouse embryonic forebrain
Q48103109Physiologically distinct temporal cohorts of cortical interneurons arise from telencephalic Olig2-expressing precursors
Q48642193Pigment epithelium-derived factor is a niche signal for neural stem cell renewal.
Q41096616Pioneer neurog1 expressing cells ingress into the otic epithelium and instruct neuronal specification.
Q34697693Pioneer transcription factors in cell reprogramming
Q34273843Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming
Q38776431Playing with the cell cycle to build the spinal cord
Q52860108Pleiotropic Hes-1 Concomitant with its Differential Activation Mediates Neural Stem Cell Maintenance and Radial Glial Propensity in Developing Neocortex.
Q50738647Polarized neural stem cells derived from adult bone marrow stromal cells develop a rosette-like structure.
Q35893618Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation.
Q28510690Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche
Q28591563Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits
Q28574941Prenatal exposure of ethanol induces increased glutamatergic neuronal differentiation of neural progenitor cells
Q51897021Preservation of positional identity in fetus-derived neural stem (NS) cells from different mouse central nervous system compartments.
Q60706839Primary Sensory Neuron Addition in the Adult Rat Trigeminal Ganglion: Evidence for Neural Crest Glio-Neuronal Precursor Maturation
Q42106919Pro-photoreceptor activity of chick neurogenin1.
Q92524935Probing disrupted neurodevelopment in autism using human stem cell-derived neurons and organoids: An outlook into future diagnostics and drug development
Q53364771Progenitor cell maturation in the developing vertebrate retina.
Q37397887Progression of neurogenesis in the inner ear requires inhibition of Sox2 transcription by neurogenin1 and neurod1.
Q46056823Prokineticin 2 is a target gene of proneural basic helix-loop-helix factors for olfactory bulb neurogenesis
Q38359098Prokineticin receptor 2 expression identifies migrating neuroblasts and their subventricular zone transient-amplifying progenitors in adult mice.
Q34441196Promoted neuronal differentiation after activation of alpha4/beta2 nicotinic acetylcholine receptors in undifferentiated neural progenitors
Q34461145Promotion of both proliferation and neuronal differentiation in pluripotent P19 cells with stable overexpression of the glutamine transporter slc38a1
Q30497390Proneural and abdominal Hox inputs synergize to promote sensory organ formation in the Drosophila abdomen.
Q34744381Proneural bHLH neurogenin 2 differentially regulates Nurr1-induced dopamine neuron differentiation in rat and mouse neural precursor cells in vitro.
Q92000787Proneural factors Ascl1 and Neurog2 contribute to neuronal subtype identities by establishing distinct chromatin landscapes
Q42027710Proneural gene ash1 promotes amacrine cell production in the chick retina
Q47073975Proneural gene requirement for hair cell differentiation in the zebrafish lateral line.
Q33975612Proneural transcription factor Atoh1 drives highly efficient differentiation of human pluripotent stem cells into dopaminergic neurons
Q35006472Proneural, prosensory, antiglial: the many faces of neurogenins
Q37615847Proper connectivity of Drosophila motion detector neurons requires Atonal function in progenitor cells.
Q28593226Protein tyrosine phosphatase receptor type O regulates development and function of the sensory nervous system
Q53503593Prox1 regulates a transitory state for interneuron neurogenesis in the spinal cord.
Q33784912Prox1 regulates the notch1-mediated inhibition of neurogenesis
Q59530593RB and RB2/p130 genes demonstrate both specific and overlapping functions during the early steps of in vitro neural differentiation of marrow stromal stem cells
Q43079143REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells
Q30838340Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors.
Q37938761Reactive oxygen species and the neuronal fate
Q26795531Real-time imaging of bHLH transcription factors reveals their dynamic control in the multipotency and fate choice of neural stem cells
Q30740000Regeneration of Xenopus laevis spinal cord requires Sox2/3 expressing cells
Q36245074Regulation of Nematostella neural progenitors by SoxB, Notch and bHLH genes
Q37480915Regulation of downstream neuronal genes by proneural transcription factors during initial neurogenesis in the vertebrate brain.
Q36298026Regulation of locomotion and motoneuron trajectory selection and targeting by the Drosophila homolog of Olig family transcription factors.
Q36983419Regulation of motor neuron specification by phosphorylation of neurogenin 2
Q37860703Regulation of neural process growth, elaboration and structural plasticity by NF-κB.
Q39252455Regulation of neurogenin stability by ubiquitin-mediated proteolysis.
Q47069067Regulation of neuronal lineage decisions by the HES-related bHLH protein REF-1.
Q39437348Regulation of self-renewing neural progenitors by FGF/ERK signaling controls formation of the inferior colliculus
Q55021358Regulation of the Drosophila ID protein Extra macrochaetae by proneural dimerization partners.
Q33303447Regulatory pathway analysis by high-throughput in situ hybridization
Q36729325Regulatory pathways linking progenitor patterning, cell fates and neurogenesis in the ventral neural tube
Q46628041Relationship between Delta-like and proneural bHLH genes during chick retinal development.
Q36290066Reliable Genetic Labeling of Adult-Born Dentate Granule Cells Using Ascl1 CreERT2 and Glast CreERT2 Murine Lines
Q38752637Reprogramming A375 cells to induced‑resembled neuronal cells by structured overexpression of specific transcription genes
Q55129556Reprogramming Glia Into Neurons in the Peripheral Auditory System as a Solution for Sensorineural Hearing Loss: Lessons From the Central Nervous System.
Q42446785Reprogramming chick RPE progeny cells to differentiate towards retinal neurons by ash1.
Q34512602Restriction of neural precursor ability to respond to Nurr1 by early regional specification
Q39838387Retinoid signaling and neurogenin2 function are coupled for the specification of spinal motor neurons through a chromatin modifier CBP
Q34988289Retinoid signalling in the development of the central nervous system
Q42474718Role for Runx1 in the proliferation and neuronal differentiation of selected progenitor cells in the mammalian nervous system.
Q49135878Role of Nurr1 in the Generation and Differentiation of Dopaminergic Neurons from Stem Cells.
Q28505312Role of Sox2 in the development of the mouse neocortex
Q26795765Role of ZAC1 in transient neonatal diabetes mellitus and glucose metabolism
Q47604706Role of estrogen receptor beta in neural differentiation of mouse embryonic stem cells
Q47071439Role of proneural genes in the formation of the larval olfactory organ of Drosophila
Q50988417Role of the Sc C terminus in transcriptional activation and E(spl) repressor recruitment.
Q37747354Role of transcription factors in cell replacement therapies for neurodegenerative conditions
Q36144904Roles of bHLH genes in neural stem cell differentiation
Q35703376Roles of cell-extrinsic growth factors in vertebrate eye pattern formation and retinogenesis
Q35458473Roles of imprinted genes in neural stem cells
Q93160660Runx1t1 promotes the neuronal differentiation in rat hippocampus
Q34763658Runx1t1 regulates the neuronal differentiation of radial glial cells from the rat hippocampus
Q37734372SDF-1/CXCR4 Signaling Maintains Stemness Signature in Mouse Neural Stem/Progenitor Cells.
Q37088685SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors
Q50888054SWI/SNF chromatin remodeling ATPase Brm regulates the differentiation of early retinal stem cells/progenitors by influencing Brn3b expression and Notch signaling.
Q41220881Safflower Seed Oil, Containing Oleic Acid and Palmitic Acid, Enhances the Stemness of Cultured Embryonic Neural Stem Cells through Notch1 and Induces Neuronal Differentiation
Q38264928Sea urchin neural development and the metazoan paradigm of neurogenesis
Q40183861Selective expression of Bhlhb5 in subsets of early-born interneurons and late-born association neurons in the spinal cord
Q37293134Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1.
Q47273858Separable enhancer sequences regulate the expression of the neural bHLH transcription factor neurogenin 1.
Q33357061Sequence conservation and combinatorial complexity of Drosophila neural precursor cell enhancers
Q34925804Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells
Q28505327Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways
Q28768607Sequential roles for Mash1 and Ngn2 in the generation of dorsal spinal cord interneurons.
Q34005893Shared mechanisms between Drosophila peripheral nervous system development and human neurodegenerative diseases
Q37245158Shh and Gli3 activities are required for timely generation of motor neuron progenitors
Q38965986Shutdown of achaete-scute homolog-1 expression by heterogeneous nuclear ribonucleoprotein (hnRNP)-A2/B1 in hypoxia.
Q30359208Signaling and Transcription Factors during Inner Ear Development: The Generation of Hair Cells and Otic Neurons.
Q24633503Signaling mechanisms regulating adult neural stem cells and neurogenesis
Q30921133Single-cell transcriptional analysis of neuronal progenitors
Q51961854Sirt1 contributes critically to the redox-dependent fate of neural progenitors.
Q35122982Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube by inhibition of the Wnt/beta-catenin pathway
Q28585974Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit
Q34641625Sox10-dependent neural crest origin of olfactory microvillous neurons in zebrafish
Q48204866Sox2 is required for olfactory pit formation and olfactory neurogenesis through BMP restriction and Hes5 upregulation
Q34431122Sox21 promotes the progression of vertebrate neurogenesis.
Q51951587Spatial and temporal segregation of auditory and vestibular neurons in the otic placode.
Q33566654Spatiotemporal fate map of neurogenin1 (Neurog1) lineages in the mouse central nervous system
Q38647083Spatiotemporal regulation of nervous system development in the annelid Capitella teleta
Q28588084Specific requirements of sonic hedgehog signaling during oligodendrocyte development
Q36712952Specification and connectivity of neuronal subtypes in the sensory lineage.
Q36729329Specification of CNS glia from neural stem cells in the embryonic neuroepithelium
Q35068985Specification of dorsal spinal cord interneurons
Q35957140Specification of neural crest into sensory neuron and melanocyte lineages
Q41582316Specificity of Atonal and Scute bHLH factors: analysis of cognate E box binding sites and the influence of Senseless
Q35172135Sprouting, regeneration and circuit formation in the injured spinal cord: factors and activity
Q34803082Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis.
Q37309769Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation
Q36127626Sumoylation of Hes6 Regulates Protein Degradation and Hes1-Mediated Transcription
Q37705484Survival of a Novel Subset of Midbrain Dopaminergic Neurons Projecting to the Lateral Septum Is Dependent on NeuroD Proteins
Q98184101Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
Q52104347Synchronization of neurogenesis and motor neuron specification by direct coupling of bHLH and homeodomain transcription factors.
Q38696402System analysis identifies distinct and common functional networks governed by transcription factor ASCL1, in glioma and small cell lung cancer.
Q36777984Targeted disruption of NeuroD, a proneural basic helix-loop-helix factor, impairs distal lung formation and neuroendocrine morphology in the neonatal lung
Q40383980Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Q46412377The CDK8 Complex and Proneural Proteins Together Drive Neurogenesis from a Mesodermal Lineage
Q92799343The Chromatin Environment Around Interneuron Genes in Oligodendrocyte Precursor Cells and Their Potential for Interneuron Reprograming
Q34688724The Drosophila BTB domain protein Jim Lovell has roles in multiple larval and adult behaviors
Q36421064The Drosophila basic helix-loop-helix protein DIMMED directly activates PHM, a gene encoding a neuropeptide-amidating enzyme
Q37217382The Drosophila neurogenin Tap functionally interacts with the Wnt-PCP pathway to regulate neuronal extension and guidance
Q35995825The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors
Q24810485The Enhancer of split and Achaete-Scute complexes of Drosophilids derived from simple ur-complexes preserved in mosquito and honeybee
Q40936808The Hippo pathway effector Yki downregulates Wg signaling to promote retinal differentiation in the Drosophila eye.
Q40024162The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma
Q33259391The Macrostomum lignano EST database as a molecular resource for studying platyhelminth development and phylogeny
Q58550777The N terminus of Ascl1 underlies differing proneural activity of mouse and Ascl1 proteins
Q44121463The Repression of Atoh1 by Neurogenin1 during Inner Ear Development
Q30397535The Role of Atonal Factors in Mechanosensory Cell Specification and Function
Q36155106The SUMO pathway promotes basic helix-loop-helix proneural factor activity via a direct effect on the Zn finger protein senseless
Q35203598The Ser/Thr phosphatase PP2A regulatory subunit widerborst inhibits notch signaling
Q39417087The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways
Q35247850The Wnt/beta-catenin asymmetry pathway patterns the atonal ortholog lin-32 to diversify cell fate in a Caenorhabditis elegans sensory lineage
Q42564451The ascl1a and dlx genes have a regulatory role in the development of GABAergic interneurons in the zebrafish diencephalon
Q34441979The bHLH repressor Deadpan regulates the self-renewal and specification of Drosophila larval neural stem cells independently of Notch
Q34124175The basic domain of ATH5 mediates neuron-specific promoter activity during retina development
Q28507679The basic helix-loop-helix differentiation factor Nex1/MATH-2 functions as a key activator of the GAP-43 gene
Q28584931The basic helix-loop-helix factor Hand 2 regulates autonomic nervous system development
Q44831571The basic helix-loop-helix genes Hesr1/Hey1 and Hesr2/Hey2 regulate maintenance of neural precursor cells in the brain
Q34474341The basic helix-loop-helix transcription factor Nex-1/Math-2 promotes neuronal survival of PC12 cells by modulating the dynamic expression of anti-apoptotic and cell cycle regulators.
Q38786607The bristle patterning genes hairy and extramacrochaetae regulate the development of structures required for flight in Diptera.
Q35955345The calcium: an early signal that initiates the formation of the nervous system during embryogenesis
Q50643794The capsaicin receptor TRPV1 as a novel modulator of neural precursor cell proliferation.
Q39018629The cellular and molecular basis of cnidarian neurogenesis.
Q24649075The complex tale of the achaete-scute complex: a paradigmatic case in the analysis of gene organization and function during development
Q55399267The developmental origin of brain tumours: a cellular and molecular framework.
Q28586332The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning
Q38001421The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation.
Q38337997The emerging framework of mammalian auditory hindbrain development
Q37128646The emerging roles of microRNAs in CNS injuries
Q37545714The endocannabinoid system and the regulation of neural development: potential implications in psychiatric disorders.
Q36298496The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats
Q33791203The epigenetic regulator Histone Deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos
Q24672605The establishment of neuronal properties is controlled by Sox4 and Sox11
Q27023095The evolution of early neurogenesis
Q52060288The expression and function of MTG/ETO family proteins during neurogenesis.
Q33546697The function and regulation of the bHLH gene, cato, in Drosophila neurogenesis
Q33809546The gene regulatory cascade linking proneural specification with differentiation in Drosophila sensory neurons
Q89505649The interplay of atoh1 genes in the lower rhombic lip during hindbrain morphogenesis
Q39924785The kinase Sgg modulates temporal development of macrochaetes in Drosophila by phosphorylation of Scute and Pannier
Q35609571The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex
Q34163979The molecular and gene regulatory signature of a neuron.
Q36660562The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration?
Q36950087The molecular biology of ear development - "Twenty years are nothing"
Q50436594The nuclear hormone receptor gene Nr2c1 (Tr2) is a critical regulator of early retina cell patterning.
Q50905465The on/off of Pax6 controls the tempo of neuronal differentiation in the developing spinal cord.
Q36698041The prokineticins: a novel pair of regulatory peptides
Q40178115The proneural proteins Atonal and Scute regulate neural target genes through different E-box binding sites
Q28067632The rise of the starlet sea anemone Nematostella vectensis as a model system to investigate development and regeneration
Q37871914The role of Notch signaling in adult neurogenesis
Q37760085The role of bHLH genes in ear development and evolution: revisiting a 10-year-old hypothesis
Q89527531The role of cell lineage in the development of neuronal circuitry and function
Q51862454The tailless ortholog nhr-67 functions in the development of the C. elegans ventral uterus.
Q51852950The transcription factor Cux2 marks development of an A-delta sublineage of TrkA sensory neurons.
Q28586506The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling
Q54561275The ultrastructure and function of the silk-producing basitarsus in the Hilarini (Diptera: Empididae).
Q46137846The use of brain organoids to investigate neural development and disease
Q46272621The zebrafish forkhead transcription factor Foxi1 specifies epibranchial placode-derived sensory neurons
Q48963177The zinc finger transcription factor RP58 negatively regulates Rnd2 for the control of neuronal migration during cerebral cortical development.
Q46931505The α1 subunit of nicotinic acetylcholine receptors in the inner ear: transcriptional regulation by ATOH1 and co-expression with the γ subunit in hair cells.
Q38416280Therapeutical Strategies for Spinal Cord Injury and a Promising Autologous Astrocyte-Based Therapy Using Efficient Reprogramming Techniques
Q36294306Thinking about visual behavior; learning about photoreceptor function
Q35150276Together at last: bHLH and LIM-HD regulators cooperate to specify motor neurons
Q42778008Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development
Q90723195Transcription Factors That Govern Development and Disease: An Achilles Heel in Cancer
Q38177652Transcription factor 4 (TCF4) and schizophrenia: integrating the animal and the human perspective.
Q35740416Transcription factor PRDM8 is required for rod bipolar and type 2 OFF-cone bipolar cell survival and amacrine subtype identity.
Q37522979Transcription factors and neural stem cell self-renewal, growth and differentiation
Q34921758Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells
Q38597727Transcription-Factor-Dependent Control of Adult Hippocampal Neurogenesis
Q48954436Transcriptional cascade from Math1 to Mbh1 and Mbh2 is required for cerebellar granule cell differentiation.
Q26998934Transcriptional control of vertebrate neurogenesis by the proneural factor Ascl1
Q92516396Transcriptional profiling of murine retinas undergoing semi-synchronous cone photoreceptor differentiation
Q37233267Transcriptional regulation of neuronal differentiation: the epigenetic layer of complexity
Q36529477Transcriptional regulation of neuronal phenotype in mammals
Q38125662Transcriptional regulation of olfactory bulb neurogenesis
Q38959782Transcriptional regulatory events initiated by Ascl1 and Neurog2 during neuronal differentiation of P19 embryonic carcinoma cells
Q36354585Transcriptional selectors, masters, and combinatorial codes: regulatory principles of neural subtype specification
Q33625677Transgenic mouse models for studying adult neurogenesis
Q41982276Transient inactivation of Notch signaling synchronizes differentiation of neural progenitor cells
Q28119013Translational regulation of the human achaete-scute homologue-1 by fragile X mental retardation protein
Q51983579Tumorhead distribution to cytoplasmic membrane of neural plate cells is positively regulated by Xenopus p21-activated kinase 1 (X-PAK1).
Q34341432Ultradian oscillations and pulses: coordinating cellular responses and cell fate decisions
Q37785200Ultradian oscillations in Notch signaling regulate dynamic biological events
Q52315637Unconventional function of an Achaete-Scute homolog as a terminal selector of nociceptive neuron identity.
Q41785743Uncovering the link between malfunctions in Drosophila neuroblast asymmetric cell division and tumorigenesis
Q92512249Using transcription factors for direct reprogramming of neurons in vitro
Q28205692Vertebrate neurogenesis is counteracted by Sox1-3 activity
Q40267713Visualization of bHLH transcription factor interactions in living mammalian cell nuclei and developing chicken neural tube by FRET.
Q92479802WNT signaling represses astrogliogenesis via Ngn2-dependent direct suppression of astrocyte gene expression
Q35001234What Are the bona fide GSK3 Substrates?
Q92325699Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk
Q48474658Wnts blow on NeuroD1 to promote adult neuron production and diversity.
Q35842533Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies
Q44231651Xath5 regulates neurogenesis in the Xenopus olfactory placode
Q40284045Xenacoelomorpha: a case of independent nervous system centralization?
Q46483917Xenopus zinc finger transcription factor IA1 (Insm1) expression marks anteroventral noradrenergic neuron progenitors in Xenopus embryos
Q94671532YAP1/TAZ drives ependymoma-like tumour formation in mice
Q35084258Zac1 regulates cell cycle arrest in neuronal progenitors via Tcf4
Q38527382Zebrafish dorsal root ganglia neural precursor cells adopt a glial fate in the absence of neurogenin1
Q64096774Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain
Q55362576aaquetzalli is required for epithelial cell polarity and neural tissue formation in Drosophila.
Q61449446activation in the Notch signaling pathway
Q33341473atonal- and achaete-scute-related genes in the annelid Platynereis dumerilii: insights into the evolution of neural basic-Helix-Loop-Helix genes
Q38908210bHLH proteins involved in Drosophila neurogenesis are mutually regulated at the level of stability
Q47069219bHLH transcription factors regulate organ morphogenesis via activation of an ADAMTS protease in C. elegans
Q55241341let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration.
Q37212103miR-17-92 facilitates neuronal differentiation of transplanted neural stem/precursor cells under neuroinflammatory conditions.
Q26865206microRNAs: key triggers of neuronal cell fate
Q34666832p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex
Q34375548phyllopod is a target gene of proneural proteins in Drosophila external sensory organ development
Q60952334β-actin regulates a heterochromatin landscape essential for optimal induction of neuronal programs during direct reprograming

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