A novel hes5/hes6 circuitry of negative regulation controls Notch activity during neurogenesis.

scientific article published in May 2005

A novel hes5/hes6 circuitry of negative regulation controls Notch activity during neurogenesis. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YDBIO.2005.03.017
P698PubMed publication ID15893982
P5875ResearchGate publication ID7847383

P50authorDomingos HenriqueQ57009307
Rita FiorQ58797672
P2860cites workHes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanismsQ24682396
Comparative analysis of somitogenesis related genes of the hairy/Enhancer of split class in Fugu and zebrafishQ24801572
Efficient selection for high-expression transfectants with a novel eukaryotic vectorQ27860810
A region of the vertebrate neural plate in which neighbouring cells can adopt neural or epidermal fates.Q52580788
Robustness, flexibility, and the role of lateral inhibition in the neurogenic network.Q52596238
Maintenance of neuroepithelial progenitor cells by Delta–Notch signalling in the embryonic chick retinaQ60492575
Notch signaling: cell fate control and signal integration in developmentQ27861061
Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loopQ28210742
Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteinsQ28243184
Notch signaling: control of cell communication and cell fateQ28245948
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiationQ28288889
Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.Q28505355
Instability of Hes7 protein is crucial for the somite segmentation clockQ28505422
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of splitQ28577019
Regulation of notch signaling activityQ28610136
A series of normal stages in the development of the chick embryoQ29037347
Proneural genes and the specification of neural cell typesQ29616807
Expression of a Delta homologue in prospective neurons in the chickQ29619573
The expression and posttranslational modification of a neuron-specific beta-tubulin isotype during chick embryogenesisQ30455473
Notch signalling in Drosophila: three ways to use a pathwayQ33540882
The role of notch in promoting glial and neural stem cell fatesQ34132317
Neurogenesis in the vertebrate neural tubeQ34187403
Structure and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-5. Identification of the neural precursor cell-specific promoter elementQ34317297
Structure, chromosomal locus, and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and Enhancer of splitQ34466443
Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterningQ34526571
Basic helix-loop-helix factors in cortical developmentQ35171934
Opposing FGF and retinoid pathways: a signalling switch that controls differentiation and patterning onset in the extending vertebrate body axisQ35845613
Specificity for the hairy/enhancer of split basic helix-loop-helix (bHLH) proteins maps outside the bHLH domain and suggests two separable modes of transcriptional repressionQ36556397
A chimeric enhancer-of-split transcriptional activator drives neural development and achaete-scute expressionQ36569750
Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activatorsQ38321559
her3, a zebrafish member of the hairy-E(spl) family, is repressed by Notch signallingQ38340664
A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesisQ38360357
Notch activity acts as a sensor for extracellular calcium during vertebrate left-right determinationQ40601220
Cellular interactions in the developing nervous system of DrosophilaQ40666051
Interkinetic nuclear movement may provide spatial clues to the regulation of neurogenesisQ42527299
her11 is involved in the somitogenesis clock in zebrafishQ45017372
FGF receptor signalling is required to maintain neural progenitors during Hensen's node progression.Q46552117
Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesisQ48041941
cash4, a novel achaete-scute homolog induced by Hensen's node during generation of the posterior nervous systemQ48052959
Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons.Q48341860
Expression of hes6, a new member of the Hairy/Enhancer-of-split family, in mouse development.Q51079244
Autoinhibition with transcriptional delay: a simple mechanism for the zebrafish somitogenesis oscillator.Q52010517
Periodic notch inhibition by lunatic fringe underlies the chick segmentation clock.Q52110194
A comprehensive collection of chicken cDNAs.Q52112138
Spatially restricted factors cooperate with notch in the regulation of Enhancer of split genes.Q52168736
Notch signalling and the control of cell fate choices in vertebrates.Q52180338
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectneurogenesisQ1456827
P304page(s)318-333
P577publication date2005-05-01
P1433published inDevelopmental BiologyQ3025402
P1476titleA novel hes5/hes6 circuitry of negative regulation controls Notch activity during neurogenesis.
P478volume281

Reverse relations

cites work (P2860)
Q27350317A balance of BMP and notch activity regulates neurogenesis and olfactory nerve formation
Q35877495A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.
Q33305437A novel function of DELTA-NOTCH signalling mediates the transition from proliferation to neurogenesis in neural progenitor cells
Q34006424A novel reporter of notch signalling indicates regulated and random Notch activation during vertebrate neurogenesis
Q101212138A transient decrease in mitochondrial activity contributes to establish the ganglion cell fate in retina adapted for high acuity vision
Q41849764ADAM10 negatively regulates neuronal differentiation during spinal cord development.
Q28591406Acheate-scute like 1 (Ascl1) is required for normal delta-like (Dll) gene expression and notch signaling during retinal development
Q35251314Anterior Hox genes interact with components of the neural crest specification network to induce neural crest fates
Q42219354Apical constriction and epithelial invagination are regulated by BMP activity
Q38718524Atrophin protein RERE positively regulates Notch targets in the developing vertebrate spinal cord
Q33607542Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear.
Q37137771Brain-derived neurotrophic factor signaling does not stimulate subventricular zone neurogenesis in adult mice and rats
Q40245530Completing the set of h/E(spl) cyclic genes in zebrafish: her12 and her15 reveal novel modes of expression and contribute to the segmentation clock.
Q50689534Cux2 acts as a critical regulator for neurogenesis in the olfactory epithelium of vertebrates.
Q35105147Cyclin D1 promotes neurogenesis in the developing spinal cord in a cell cycle-independent manner
Q50353951Differential regulation of Hes/Hey genes during inner ear development.
Q28589374Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity
Q41613816Dynamic expression of Notch-dependent neurogenic markers in the chick embryonic nervous system.
Q42453706Dynamic expression of neurogenic markers in the developing chick olfactory epithelium
Q40648767FGF-dependent Notch signaling maintains the spinal cord stem zone
Q37440775Feedback regulation of NEUROG2 activity by MTGR1 is required for progression of neurogenesis
Q43507552Fgf10 expression patterns in the developing chick inner ear.
Q28593359Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells
Q38923075HES5 silencing is an early and recurrent change in prostate tumourigenesis
Q39277802HES6 enhances the motility of alveolar rhabdomyosarcoma cells.
Q24683388HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion
Q33769686HES6-1 and HES6-2 function through different mechanisms during neuronal differentiation
Q48112868Hairy and Enhancer of Split 6 (Hes6) Deficiency in Mouse Impairs Neuroblast Differentiation in Dentate Gyrus Without Affecting Cell Proliferation and Integration into Mature Neurons
Q34082939Hes6 is required for the neurogenic activity of neurogenin and NeuroD
Q28591962Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways
Q57041812Inhibition of cortical astrocyte differentiation by Hes6 requires amino- and carboxy-terminal motifs important for dimerization and phosphorylation
Q40578041Jagged2 controls the generation of motor neuron and oligodendrocyte progenitors in the ventral spinal cord.
Q42498612Key role played by RhoA in the balance between planar and apico-basal cell divisions in the chick neuroepithelium
Q34341301Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo
Q33827953Modelling the Delta1/Notch1 pathway: in search of the mediator(s) of neural stem cell differentiation
Q42323235NEUROG2 drives cell cycle exit of neuronal precursors by specifically repressing a subset of cyclins acting at the G1 and S phases of the cell cycle.
Q37373888NFκB signaling regulates embryonic and adult neurogenesis
Q46026506Neurogenin3 restricts serotonergic neuron differentiation to the hindbrain.
Q50491721Notch and Hedgehog in the thymus/parathyroid common primordium: Crosstalk in organ formation.
Q30483576Notch regulation of progenitor cell behavior in quiescent and regenerating auditory epithelium of mature birds.
Q42109253Notch signalling stabilises boundary formation at the midbrain-hindbrain organiser.
Q37785199Notch targets and their regulation
Q34393493Novel genes upregulated when NOTCH signalling is disrupted during hypothalamic development.
Q30627114Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear.
Q48123752Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics
Q40214468Opposing Fgf and Bmp activities regulate the specification of olfactory sensory and respiratory epithelial cell fates
Q39007241Otic placode cell specification and proliferation are regulated by Notch signaling in avian development
Q28509990Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity
Q33287045Preservation of proliferating pancreatic progenitor cells by Delta-Notch signaling in the embryonic chicken pancreas
Q53364771Progenitor cell maturation in the developing vertebrate retina.
Q24309381Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis
Q37299254Reduced Notch signalling leads to postnatal skeletal muscle hypertrophy in Pofut1cax/cax mice
Q36729325Regulatory pathways linking progenitor patterning, cell fates and neurogenesis in the ventral neural tube
Q42629116Somitogenesis in the anole lizard and alligator reveals evolutionary convergence and divergence in the amniote segmentation clock.
Q48204866Sox2 is required for olfactory pit formation and olfactory neurogenesis through BMP restriction and Hes5 upregulation
Q33903422The Enhancer of split transcription factor Her8a is a novel dimerisation partner for Her3 that controls anterior hindbrain neurogenesis in zebrafish
Q37522979Transcription factors and neural stem cell self-renewal, growth and differentiation
Q35001705Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling
Q41982276Transient inactivation of Notch signaling synchronizes differentiation of neural progenitor cells
Q41648605Unraveling the differential dynamics of developmental fate in central and peripheral nervous systems
Q27345167Zebrafish Her8a is activated by Su(H)-dependent Notch signaling and is essential for the inhibition of neurogenesis

Search more.