Cell cycle regulation of proliferation versus differentiation in the central nervous system.

scientific article published on 25 May 2014

Cell cycle regulation of proliferation versus differentiation in the central nervous system. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1034947403
P356DOI10.1007/S00441-014-1895-8
P2888exact matchhttps://scigraph.springernature.com/pub.10.1007/s00441-014-1895-8
P932PMC publication ID4284380
P698PubMed publication ID24859217
P5875ResearchGate publication ID262610535

P50authorRoberta AzzarelliQ58762346
Anna PhilpottQ60622167
P2093author name stringLaura J A Hardwick
Fahad R Ali
P2860cites workDevelopment and evolution of the human neocortexQ22337363
Cdk6-dependent regulation of G(1) length controls adult neurogenesisQ24293050
A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cellsQ24300496
Geminin, an inhibitor of DNA replication, is degraded during mitosisQ24309195
Geminin regulates neuronal differentiation by antagonizing Brg1 activityQ24531381
Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesisQ24624356
Co-ordination of cell cycle and differentiation in the developing nervous systemQ26996654
Molecular mechanisms underlying RB protein functionQ27003956
CDK inhibitors: positive and negative regulators of G1-phase progressionQ27860983
Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phasesQ28236938
The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactionsQ28245999
Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain developmentQ28261372
Oscillations in notch signaling regulate maintenance of neural progenitorsQ28275810
Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulationQ28277033
FoxM1-driven cell division is required for neuronal differentiation in early Xenopus embryos.Q51957533
Cell cycling and differentiation do not require the retinoblastoma protein during early Xenopus development.Q51998536
The developmental expression of cell cycle regulators in Xenopus laevis.Q52106307
The cdk inhibitor p27Xic1 is required for differentiation of primary neurones in Xenopus.Q52112242
p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina.Q52166705
The CDC25B phosphatase shortens the G2 phase of neural progenitors and promotes efficient neuron production.Q53186850
p27Xic1, a Cdk inhibitor, promotes the determination of glial cells in Xenopus retinaQ73253272
Simultaneous suppression of cdc2 and cdk2 activities induces neuronal differentiation of PC12 cellsQ73704050
Radioautographic study of interkinetic nuclear migration in the neural tubeQ78744157
Cdk5 phosphorylates and stabilizes p27kip1 contributing to actin organization and cortical neuronal migrationQ81601109
OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signalingQ42470977
Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells.Q42505393
Geminin restrains mesendodermal fate acquisition of embryonic stem cells and is associated with antagonism of Wnt signaling and enhanced polycomb-mediated repressionQ42630636
p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations.Q43638899
Lack of the cell-cycle inhibitor p27Kip1 results in selective increase of transit-amplifying cells for adult neurogenesis.Q43918838
Co-ordinating retinal histogenesis: early cell cycle exit enhances early cell fate determination in the Xenopus retinaQ43969921
Extra-embryonic function of Rb is essential for embryonic development and viabilityQ44329398
Requirement for a functional Rb-1 gene in murine developmentQ44462954
Global analysis of gene expression in neural progenitors reveals specific cell-cycle, signaling, and metabolic networksQ44563877
An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesisQ44660997
Overexpression of p27 Kip 1, probability of cell cycle exit, and laminar destination of neocortical neuronsQ45221848
Altered patterns of neuron production in the p27 knockout mouseQ45265185
A short G1 phase is an intrinsic determinant of naïve embryonic stem cell pluripotency.Q45981346
A crucial role for p57(Kip2) in the intracellular timer that controls oligodendrocyte differentiationQ46498298
G1/S phase cyclin-dependent kinase overexpression perturbs early development and delays tissue-specific differentiation in Xenopus.Q47679361
Radial glia serve as neuronal progenitors in all regions of the central nervous systemQ47874917
X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiationQ48056539
Nobel Lecture. Cyclin dependent kinases and cell cycle control.Q48357444
The cyclin-dependent kinase inhibitors p57 and p27 regulate neuronal migration in the developing mouse neocortex.Q48375804
Predicting stem cell fate changes by differential cell cycle progression patterns.Q48750437
Modulation of cell-cycle dynamics is required to regulate the number of cerebellar GABAergic interneurons and their rhythm of maturation.Q49031578
Constructing the cerebral cortex: Neurogenesis and fate determinationQ40423295
Id2 mediates tumor initiation, proliferation, and angiogenesis in Rb mutant mice.Q40435177
Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous systemQ41078523
Geminin regulates the transcriptional and epigenetic status of neuronal fate-promoting genes during mammalian neurogenesisQ41581971
Activation of Xenopus genes required for lateral inhibition and neuronal differentiation during primary neurogenesisQ41706007
Progressive restriction in fate potential by neural progenitors during cerebral cortical development.Q41741155
How to keep proliferative neural stem/progenitor cells: a critical role of asymmetric inheritance of cyclin D2Q41865122
Oscillatory control of factors determining multipotency and fate in mouse neural progenitorsQ42258504
NEUROG2 drives cell cycle exit of neuronal precursors by specifically repressing a subset of cyclins acting at the G1 and S phases of the cell cycle.Q42323235
Neuronal or glial progeny: regional differences in radial glia fateQ42438070
Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors.Q42459454
The cell biology of neurogenesisQ28284165
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiationQ28288889
Control of cell cycle transcription during G1 and S phasesQ28295030
FoxM1 is required for execution of the mitotic programme and chromosome stabilityQ28302862
p21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal.Q28360415
Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcriptionQ28507962
A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targetsQ28508329
Characterization of CNS precursor subtypes and radial gliaQ28508337
Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancersQ28508842
Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiationQ28513619
p57(Kip2) cooperates with Nurr1 in developing dopamine cellsQ28587845
Generation of neurons by transient expression of neural bHLH proteins in mammalian cellsQ28588730
Principles of CDK regulationQ29547820
Neurogenic radial glia in the outer subventricular zone of human neocortexQ29616182
Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortexQ29616194
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumorsQ29616203
Proneural genes and the specification of neural cell typesQ29616807
Effects of an Rb mutation in the mouseQ29619196
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesisQ29619200
A cell-autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration.Q30476691
Forced G1-phase reduction alters mode of division, neuron number, and laminar phenotype in the cerebral cortex.Q30492178
Depletion of the cell-cycle inhibitor p27(Xic1) impairs neuronal differentiation and increases the number of ElrC(+) progenitor cells in Xenopus tropicalisQ30940873
Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a.Q33289781
Cyclin D2 is critical for intermediate progenitor cell proliferation in the embryonic cortexQ33609469
A cell-intrinsic timer that operates during oligodendrocyte developmentQ33825394
Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteinsQ33921667
Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineageQ33925185
Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous systemQ34080329
A decade of CDK5.Q34093501
Specification of neuronal fates in the ventral neural tubeQ34141441
Cell cycle and cell fate in the nervous system.Q34141459
The Rb pathway in neurogenesisQ34298146
Complex regulation controls Neurogenin3 proteolysis.Q34319004
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).Q34381917
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient miceQ34381923
Rb/E2F regulates expression of neogenin during neuronal migrationQ34485077
p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortexQ34666832
Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brainQ34973654
Induction and patterning of neuronal development, and its connection to cell cycle controlQ35068973
Cell cycle and cell fate interactions in neural developmentQ35068976
Cyclin D1 promotes neurogenesis in the developing spinal cord in a cell cycle-independent mannerQ35105147
The cyclin-dependent kinase inhibitor p57Kip2 regulates cell cycle exit, differentiation, and migration of embryonic cerebral cortical precursorsQ35111678
Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb -deficient miceQ35143505
Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesisQ35208724
Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formationQ35421560
Roles of p53 and p27(Kip1) in the regulation of neurogenesis in the murine adult subventricular zoneQ35545392
Neurogenesis and the Cell CycleQ35558404
p57(KIP2) regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortexQ35655615
Geminin coordinates cell cycle and developmental controlQ35778488
Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation.Q35893618
The regulation of embryonic patterning and DNA replication by gemininQ36116139
p27(KIP1) regulates neurogenesis in the rostral migratory stream and olfactory bulb of the postnatal mouseQ36368949
Geminin's double life: chromatin connections that regulate transcription at the transition from proliferation to differentiation.Q36396656
p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.Q36546981
Coupling cell cycle exit, neuronal differentiation and migration in cortical neurogenesisQ36653014
Regulation of motor neuron specification by phosphorylation of neurogenin 2Q36983419
An unusual member of the Cdk family: Cdk5.Q37053631
Neurogenesis and asymmetric cell divisionQ37177866
Cell-cycle control of developmentally regulated transcription factors accounts for heterogeneity in human pluripotent cellsQ37410891
The cell-cycle state of stem cells determines cell fate propensity.Q37504042
Cdks and cyclins link G1 length and differentiation of embryonic, neural and hematopoietic stem cellsQ37740912
Oscillatory control of signalling moleculesQ37790024
Cortical progenitor expansion, self-renewal and neurogenesis-a polarized perspectiveQ37805233
The multiple roles of the cyclin-dependent kinase inhibitory protein p57(KIP2) in cerebral cortical neurogenesisQ37955145
Proneural genes in neocortical development.Q38133691
The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.Q38333613
Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryoQ38339142
Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.Q38347118
Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical developmentQ39647556
p57Kip2 is a repressor of Mash1 activity and neuronal differentiation in neural stem cells.Q39826816
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectnervous systemQ9404
cell differentiationQ210861
P304page(s)187-200
P577publication date2014-05-25
2015-01-01
P1433published inCell and Tissue ResearchQ1524113
P1476titleCell cycle regulation of proliferation versus differentiation in the central nervous system
P478volume359

Reverse relations

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