Co-ordination of cell cycle and differentiation in the developing nervous system

scientific article

Co-ordination of cell cycle and differentiation in the developing nervous system is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1042/BJ20112040
P932PMC publication ID3365434
P698PubMed publication ID22642576

P2093author name stringAnna Philpott
Christopher Hindley
P2860cites workCdk6-dependent regulation of G(1) length controls adult neurogenesisQ24293050
Geminin, an inhibitor of DNA replication, is degraded during mitosisQ24309195
A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2Q24309204
Direct interaction of geminin and Six3 in eye developmentQ24310108
Geminin regulates neuronal differentiation by antagonizing Brg1 activityQ24531381
Retinoblastoma family genesQ24683690
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cellsQ26269888
Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferationQ28117650
Vertebrate neurogenesis is counteracted by Sox1-3 activityQ28205692
NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1Q72038021
p27Xic1, a Cdk inhibitor, promotes the determination of glial cells in Xenopus retinaQ73253272
Geminin bans replication licenceQ73435258
Simultaneous suppression of cdc2 and cdk2 activities induces neuronal differentiation of PC12 cellsQ73704050
Over-expression of FoxM1 stimulates cyclin B1 expressionQ77078785
Sox1 maintains the undifferentiated state of cortical neural progenitor cells via the suppression of Prox1-mediated cell cycle exit and neurogenesisQ83328386
Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroDQ28215336
Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitmentQ28235209
The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactionsQ28245999
Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanismQ28256059
Oscillations in notch signaling regulate maintenance of neural progenitorsQ28275810
Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulationQ28277033
The regulation of E2F by pRB-family proteinsQ28278789
FoxM1 is required for execution of the mitotic programme and chromosome stabilityQ28302862
Phosphorylation state of Olig2 regulates proliferation of neural progenitorsQ28306707
Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophagesQ28507476
Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcriptionQ28507962
A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targetsQ28508329
Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosisQ28511665
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversificationQ28512492
Identification of neurogenin, a vertebrate neuronal determination geneQ28564456
Generation of neurons by transient expression of neural bHLH proteins in mammalian cellsQ28588730
Foxg1 suppresses early cortical cell fateQ28588844
Specificity and versatility in tgf-beta signaling through SmadsQ29616324
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancerQ29616379
Proneural genes and the specification of neural cell typesQ29616807
"Stemness": transcriptional profiling of embryonic and adult stem cellsQ29618765
Geminin-deficient neural stem cells exhibit normal cell division and normal neurogenesisQ33847145
Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiationQ33885995
A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivoQ33916094
SOX2 functions to maintain neural progenitor identityQ33968061
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).Q34381917
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient miceQ34381923
Sox21 promotes the progression of vertebrate neurogenesis.Q34431122
p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortexQ34666832
Cell cycle dependence of laminar determination in developing neocortexQ34955579
Ubiquitylation on canonical and non-canonical sites targets the transcription factor neurogenin for ubiquitin-mediated proteolysisQ34972149
Cyclin D1 promotes neurogenesis in the developing spinal cord in a cell cycle-independent mannerQ35105147
The cyclin-dependent kinase inhibitor p57Kip2 regulates cell cycle exit, differentiation, and migration of embryonic cerebral cortical precursorsQ35111678
Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesisQ35208724
Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formationQ35421560
Old and new functions of proneural factors revealed by the genome-wide characterization of their transcriptional targets.Q35737574
SOX genes and neural progenitor identityQ36049176
Cdk2 is critical for proliferation and self-renewal of neural progenitor cells in the adult subventricular zoneQ36274559
A unique pattern of photoreceptor degeneration in cyclin D1 mutant miceQ36280960
Geminin's double life: chromatin connections that regulate transcription at the transition from proliferation to differentiation.Q36396656
RB1, development, and cancerQ36950978
Distinct developmental roles of cell cycle inhibitors p57Kip2 and p27Kip1 distinguish pituitary progenitor cell cycle exit from cell cycle reentry of differentiated cellsQ37128025
The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.Q38333613
Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryoQ38339142
Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.Q38347118
Expression of FoxM1 is required for the proliferation of medulloblastoma cells and indicates worse survival of patientsQ39473733
Notch induces cyclin-D1-dependent proliferation during a specific temporal window of neural differentiation in ES cells.Q39649080
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligaseQ40700999
Xenopus Sox3 activates sox2 and geminin and indirectly represses Xvent2 expression to induce neural progenitor formation at the expense of non-neural ectodermal derivativesQ41896090
Notch targets the Cdk inhibitor Xic1 to regulate differentiation but not the cell cycle in neuronsQ42037180
Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors.Q42459454
Differences in cyclin D2 and D1 protein expression distinguish forebrain progenitor subsetsQ42683659
Abdominal-A mediated repression of Cyclin E expression during cell-fate specification in the Drosophila central nervous system.Q44185432
Global analysis of gene expression in neural progenitors reveals specific cell-cycle, signaling, and metabolic networksQ44563877
An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesisQ44660997
Cell cycle independent role of Cyclin E during neural cell fate specification in Drosophila is mediated by its regulation of Prospero function.Q44740868
Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene DeltaQ46026585
p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitorsQ46193497
A critical role for cyclin E in cell fate determination in the central nervous system of Drosophila melanogasterQ47072874
G1/S phase cyclin-dependent kinase overexpression perturbs early development and delays tissue-specific differentiation in Xenopus.Q47679361
Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: their expression during embryonic organogenesis of the chickenQ47932230
Cerebellar histogenesis is disturbed in mice lacking cyclin D2.Q48249499
Transforming growth factor-beta1 is a negative modulator of adult neurogenesisQ48543560
Differential expression of D-type G1 cyclins during mouse development and liver regeneration in vivoQ49015677
Modulation of cell-cycle dynamics is required to regulate the number of cerebellar GABAergic interneurons and their rhythm of maturation.Q49031578
Geminin regulates cortical progenitor proliferation and differentiationQ49158436
FoxM1-driven cell division is required for neuronal differentiation in early Xenopus embryos.Q51957533
The developmental expression of cell cycle regulators in Xenopus laevis.Q52106307
The cdk inhibitor p27Xic1 is required for differentiation of primary neurones in Xenopus.Q52112242
A single cdk inhibitor, p27Xic1, functions beyond cell cycle regulation to promote muscle differentiation in Xenopus.Q52112244
Cyclin D1 provides a link between development and oncogenesis in the retina and breastQ52206604
A double-assurance mechanism controls cell cycle exit upon terminal differentiation in Drosophila.Q52678751
Division versus differentiation in the early Xenopus embryo.Q53489174
Prox1 regulates a transitory state for interneuron neurogenesis in the spinal cord.Q53503593
NMR and mass spectrometry studies of putative interactions of cell cycle proteins pRb and CDK6 with cell differentiation proteins MyoD and ID-2.Q53677234
Control of Müller glial cell proliferation and activation following retinal injury.Q55034188
Evidence that helix-loop-helix proteins collaborate with retinoblastoma tumor suppressor protein to regulate cortical neurogenesisQ57042317
P275copyright licenseCreative Commons Attribution-NonCommercial 2.5 GenericQ19113746
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectnervous systemQ9404
neurogenesisQ1456827
physiological phenomenonQ66615932
P304page(s)375-82
P577publication date2012-06-15
P1433published inBiochemical JournalQ864221
P1476titleCo-ordination of cell cycle and differentiation in the developing nervous system
P478volume444

Reverse relations

cites work (P2860)
Q41930994APC/C-Cdh1 coordinates neurogenesis and cortical size during development
Q51049438C8orf46 homolog encodes a novel protein Vexin that is required for neurogenesis in Xenopus laevis
Q37692715CXCR7 Participates in CXCL12-mediated Cell Cycle and Proliferation Regulation in Mouse Neural Progenitor Cells.
Q38611877Cdk4 regulates adult neural stem cell proliferation and differentiation in response to insulin-IRS2 signals
Q45879660Cell Cycle Proteins and Retinal Degeneration: Evidences of New Potential Therapeutic Targets
Q38214508Cell cycle regulation of proliferation versus differentiation in the central nervous system.
Q36189433Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells
Q64053559Dlx5 and Dlx6 can antagonize cell division at the G/S checkpoint
Q28804198Evaluation of Possible Consequences of Zika Virus Infection in the Developing Nervous System
Q88426282Feedback between tissue packing and neurogenesis in the zebrafish neural tube
Q46716718Live-cell time-lapse imaging and single-cell tracking of in vitro cultured neural stem cells - Tools for analyzing dynamics of cell cycle, migration, and lineage selection
Q28512506Maturin is a novel protein required for differentiation during primary neurogenesis
Q33854168Molecular ties between the cell cycle and differentiation in embryonic stem cells
Q37420213Pathway modulations and epigenetic alterations in ovarian tumorbiogenesis
Q38776431Playing with the cell cycle to build the spinal cord
Q36742209Proliferation rate of somatic cells affects reprogramming efficiency
Q33991641Protection of neurons from high glucose-induced injury by deletion of MAD2B
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Q55362701Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders.
Q33952905The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation
Q37332227Transcriptome study of differential expression in schizophrenia
Q64966578Vrk1 partial Knockdown in Mice Results in Reduced Brain Weight and Mild Motor Dysfunction, and Indicates Neuronal VRK1 Target Pathways.
Q37318020Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development
Q42566243aPKC phosphorylates p27Xic1, providing a mechanistic link between apicobasal polarity and cell-cycle control
Q28566173p15(INK4b) regulates cell cycle signaling in hippocampal astrocytes of aged rats

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