Insulin-producing cells derived from stem cells: recent progress and future directions

scientific article published on October 2006

Insulin-producing cells derived from stem cells: recent progress and future directions is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1582-4934.2006.TB00531.X
P698PubMed publication ID17125591

P50authorEnrique RocheQ57337490
P2093author name stringMaría Isabel Arribas
J A Reig
A Santana
R Enseñat-Waser
P2860cites workDifferentiation of insulin-producing cells from human neural progenitor cellsQ21092394
Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cellsQ24680036
Directed differentiation of rhesus monkey ES cells into pancreatic cell phenotypesQ24802550
Triggering and amplifying pathways of regulation of insulin secretion by glucoseQ27863677
Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretionQ27876210
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimenQ28141785
Regulation of insulin gene transcriptionQ28210255
Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineagesQ28278091
Combined expression of pancreatic duodenal homeobox 1 and islet factor 1 induces immature enterocytes to produce insulinQ28567058
Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemiaQ28583342
Transcription factors direct the development and function of pancreatic beta cellsQ28609099
Molecular determinants of regulated exocytosisQ28609688
53BP1 is required for class switch recombinationQ29465541
Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor CellsQ29541158
Global and societal implications of the diabetes epidemicQ29614551
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiationQ29614736
Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypesQ33181775
Five-year follow-up after clinical islet transplantationQ33218078
Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets.Q33944464
Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamusQ34124441
Glucose-sensing mechanisms in eukaryotic cells.Q34245438
From stem cells to beta cells: new strategies in cell therapy of diabetes mellitus.Q34253731
Islet Regeneration During the Reversal of Autoimmune Diabetes in NOD MiceQ34276533
Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cellsQ34328388
Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine pancreas developmental pathway upon genetic and/or microenvironmental manipulation in vitroQ34406295
Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cellsQ34415516
Embryo-derived stem cells: of mice and men.Q34425188
Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function.Q34427073
Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells.Q34491740
Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regenerationQ34504662
Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contributionQ34504668
Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells.Q34504674
Proinsulin in development: New roles for an ancient prohormone.Q34510776
V(D)J recombination: RAG proteins, repair factors, and regulationQ34667417
In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusionQ34967985
Gene expression cascades in pancreatic developmentQ35029666
Reconstructing MYC.Q35120942
In vitro cultivation of human islets from expanded ductal tissueQ35174217
Nuclear transplantation, embryonic stem cells, and the potential for cell therapyQ35179632
Insulin granule dynamics in pancreatic beta cellsQ35184211
Incretins, insulin secretion and Type 2 diabetes mellitusQ35669308
Plasticity of adult stem cellsQ35684656
Myc: a weapon of mass destructionQ35745736
Nuclear reprogramming: a key to stem cell function in regenerative medicineQ35876043
Differential expression of the two nonallelic proinsulin genes in the developing mouse embryoQ36059091
Differentiation of rat marrow mesenchymal stem cells into pancreatic islet beta-cellsQ36076469
How to make pancreatic beta cells--prospects for cell therapy in diabetesQ36220822
Insulin-secreting cells derived from stem cells: clinical perspectives, hypes and hopesQ36368247
Growing new endocrine pancreas in situQ36424061
Are there pancreatic progenitor cells from which new islets form after birth?Q36577005
The development of diabetes in E2f1/E2f2 mutant mice reveals important roles for bone marrow-derived cells in preventing islet cell lossQ36689966
The use of gating technology in bioengineering insulin-secreting cells from embryonic stem cellsQ37323527
Glucagon-like peptide-1 enhances production of insulin in insulin-producing cells derived from mouse embryonic stem cellsQ40389281
Similarities of K+ATP channel expression and Ca2+ changes in pancreatic beta cells and hypothalamic neuronsQ40443990
Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cellsQ40483254
AMP-activated protein kinase: a new beta-cell glucose sensor?: Regulation by amino acids and calcium ionsQ40488463
Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cellsQ40521874
Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cellsQ40544422
Development of definitive endoderm from embryonic stem cells in cultureQ40582761
Insulin expressing cells from differentiated embryonic stem cells are not beta cellsQ40589116
Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the isletQ40630843
PDX-1 induces differentiation of intestinal epithelioid IEC-6 into insulin-producing cells.Q40715041
Generation of purified neural precursors from embryonic stem cells by lineage selectionQ41008017
Mechanisms of action of nonglucose insulin secretagoguesQ41053123
Transforming growth factor (TGF)beta, fibroblast growth factor (FGF) and retinoid signalling pathways promote pancreatic exocrine gene expression in mouse embryonic stem cellsQ41862814
Unprocessed proinsulin promotes cell survival during neurulation in the chick embryo.Q43901627
Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetesQ44007215
Retinoic acid signaling is required for a critical early step in zebrafish pancreatic developmentQ44101109
NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in miceQ44409461
Analysis of insulin-producing cells during in vitro differentiation from feeder-free embryonic stem cellsQ44418714
Bone marrow-derived stem cells initiate pancreatic regeneration.Q44486484
Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic beta cellsQ44536342
No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivoQ44779240
Differentiation of human embryonic stem cells into insulin-producing clustersQ44903372
Artifactual insulin release from differentiated embryonic stem cellsQ45077937
Committing embryonic stem cells to early endocrine pancreas in vitroQ45173529
The in vitro differentiation of rat neural stem cells into an insulin-expressing phenotypeQ45185279
Embryonic stem cells differentiate into insulin-producing cells without selection of nestin-expressing cells.Q45189356
In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cellsQ45199702
Reversal of experimental diabetes by multiple bone marrow transplantationQ45238329
Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic miceQ45868872
Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acidQ46453422
Differentiation of in vitro-modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cellsQ46531971
Induction of differentiation of embryonic stem cells into insulin-secreting cells by fetal soluble factors.Q46658312
Hypothalamic glucose sensor: similarities to and differences from pancreatic beta-cell mechanisms.Q48116728
Distribution and phenotype of neurons containing the ATP-sensitive K+ channel in rat brainQ48337960
Isolation and characterization of residual undifferentiated mouse embryonic stem cells from embryoid body cultures by fluorescence trackingQ48930639
Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells.Q52117012
Spontaneous human adult stem cell transformation.Q53358878
In vitro directed differentiation of mouse embryonic stem cells into insulin-producing cells.Q53888618
Recruitment of Bone Marrow-Derived Endothelial Cells to Sites of Pancreatic -Cell InjuryQ57720869
More than just proliferation: Myc function in stem cellsQ58379812
P433issue4
P304page(s)866-883
P577publication date2006-10-01
P1433published inJournal of Cellular and Molecular MedicineQ1524063
P1476titleInsulin-producing cells derived from stem cells: recent progress and future directions
P478volume10

Reverse relations

cites work (P2860)
Q38085695Adipose-derived mesenchymal stem cells and regenerative medicine
Q43111293Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets
Q34374773Evaluating protocols for embryonic stem cell differentiation into insulin-secreting beta-cells using insulin II-GFP as a specific and noninvasive reporter
Q34132912Identification of microRNAs expressed highly in pancreatic islet-like cell clusters differentiated from human embryonic stem cells.
Q33316754Immunohistochemical analysis of neuroendocrine (NE) differentiation in testicular germ cell tumors (GCTs): use of confocal laser scanning microscopy (CLSM) to demonstrate direct NE differentiation from GCTs
Q27693217Induced pluripotent stem cells as a model for accelerated patient- and disease-specific drug discovery.
Q37445891Infusion of UVB-treated splenic stromal cells induces suppression of beta cell antigen-specific T cell responses in NOD mice
Q34591457Insulin-producing cells could not mimic the physiological regulation of insulin secretion performed by pancreatic beta cells
Q36884245Molecular and cellular key players in human islet transplantation
Q36710960Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation
Q37276010Peripheral blood monocytes can differentiate into efficient insulin-producing cells in vitro
Q38191830Pluripotent stem cells as a potential tool for disease modelling and cell therapy in diabetes.
Q33719099Recent progress on normal and malignant pancreatic stem/progenitor cell research: therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer
Q37089825Recent progress on tissue-resident adult stem cell biology and their therapeutic implications
Q33982394Stem cells as a therapeutic target for diabetes.
Q40321403Transplantation of placenta-derived mesenchymal stem cells in type 2 diabetes: a pilot study
Q36269896Uncovering stem cell differentiation factors for salivary gland regeneration by quantitative analysis of differential proteomes

Search more.