scholarly article | Q13442814 |
P2093 | author name string | Mark A Lehrman | |
Ningguo Gao | |||
Jianfeng Du | |||
Guy J Leclerc | |||
Julio C Barredo | |||
Gilles M Leclerc | |||
Joanna DeSalvo | |||
Theodore J Lampidis | |||
P2860 | cites work | Hallmarks of Cancer: The Next Generation | Q22252312 |
Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent manner | Q24298269 | ||
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis | Q24306444 | ||
Translational implications of tumor heterogeneity | Q26822823 | ||
Is this the time to introduce minimal residual disease in multiple myeloma clinical practice? | Q28087357 | ||
A phase I dose-escalation trial of 2-deoxy-D-glucose alone or combined with docetaxel in patients with advanced solid tumors | Q28281237 | ||
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway | Q29620730 | ||
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia | Q33694514 | ||
Significance of Circulating Tumor Cells in Metastatic Triple-Negative Breast Cancer Patients within a Randomized, Phase II Trial: TBCRC 019 | Q33923080 | ||
Folylpolyglutamate synthetase gene transcription is regulated by a multiprotein complex that binds the TEL-AML1 fusion in acute lymphoblastic leukemia | Q34161064 | ||
P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling | Q34179244 | ||
A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo | Q34241381 | ||
Clitocine targets Mcl-1 to induce drug-resistant human cancer cell apoptosis in vitro and tumor growth inhibition in vivo | Q34406244 | ||
Detection of resistance to imatinib by metabolic profiling: clinical and drug development implications | Q34561387 | ||
AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia | Q34647789 | ||
CCR 20th anniversary commentary: BMS-247550—microtubule stabilization as successful targeted therapy | Q35185097 | ||
The c-Met Tyrosine Kinase Inhibitor JNJ-38877605 Causes Renal Toxicity through Species-Specific Insoluble Metabolite Formation | Q35612898 | ||
Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives | Q35836881 | ||
BH3-only proteins in control: specificity regulates MCL-1 and BAK-mediated apoptosis | Q36152548 | ||
Treatment of acute lymphoblastic leukemia | Q36366185 | ||
Elucidation of Acquired Resistance to Bcl-2 and MDM2 Inhibitors in Acute Leukemia In Vitro and In Vivo. | Q37118668 | ||
Mcl-1; the molecular regulation of protein function | Q37764383 | ||
Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. | Q37865381 | ||
Preclinical development of novel anti-glioma drugs targeting the endoplasmic reticulum stress response | Q37914268 | ||
Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery? | Q38423044 | ||
SIRT1/PGC1α-Dependent Increase in Oxidative Phosphorylation Supports Chemotherapy Resistance of Colon Cancer | Q38465646 | ||
Targeting FGFR Signaling in Cancer | Q38528810 | ||
Activity of MM-398, nanoliposomal irinotecan (nal-IRI), in Ewing's family tumor xenografts is associated with high exposure of tumor to drug and high SLFN11 expression | Q38904399 | ||
Interaction of Nck1 and PERK phosphorylated at Y⁵⁶¹ negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content | Q39039522 | ||
Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924. | Q39253047 | ||
Inhibition of Akt potentiates 2-DG-induced apoptosis via downregulation of UPR in acute lymphoblastic leukemia | Q39332231 | ||
Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation | Q40048066 | ||
Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation. | Q40453406 | ||
Imatinib (STI571)-mediated changes in glucose metabolism in human leukemia BCR-ABL-positive cells | Q40505762 | ||
MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol | Q40537978 | ||
Conditional Survival: A Useful Concept to Provide Information on How Prognosis Evolves over Time | Q41126191 | ||
CCR 20th Anniversary commentary: in search of cetuximab's first indication-combination therapy with irinotecan in colorectal cancer | Q41126194 | ||
Interference with glycosylation of glycoproteins. Inhibition of formation of lipid-linked oligosaccharides in vivo | Q41991311 | ||
Prognostic Significance of Tryptophan Catabolism in Adult T-cell Leukemia/Lymphoma. | Q42153876 | ||
The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance | Q42831411 | ||
Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation. | Q43228472 | ||
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. | Q43561629 | ||
Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow toward nucleic acid and fatty acid synthesis in myeloid tumor cells. | Q43699000 | ||
"Vertical" Inhibition of HER2 Yields Horizontal Gains in the Clinic | Q46397563 | ||
PLEKHA5: A Key to Unlock the Blood-Brain Barrier? | Q48276978 | ||
CCR 20th Anniversary Commentary: Expanding the Epigenetic Therapeutic Portfolio. | Q50586720 | ||
CCR 20th Anniversary Commentary: From Regulatory T Cells to Checkpoint Monoclonal Antibodies--Immuno-oncology Advances Clinical Cancer Research. | Q50852978 | ||
Quit early, quit often | Q87319502 | ||
P577 | publication date | 2015-08-20 | |
P1433 | published in | Leukemia Research | Q15716445 |
P1476 | title | Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress |
Q90412228 | By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737 |
Q49787961 | Inhibition of the NEDD8 conjugation pathway induces calcium-dependent compensatory activation of the pro-survival MEK/ERK pathway in acute lymphoblastic leukemia |
Q60948306 | Synergistic AML Cell Death Induction by Marine Cytotoxin (+)-1(), 6(), 1'(), 6'(), 11(), 17()-Fistularin-3 and Bcl-2 Inhibitor Venetoclax |
Q89552648 | The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias |
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