Reconstitution of transcriptional activation domains by reiteration of short peptide segments reveals the modular organization of a glutamine-rich activation domain

scientific article published on September 1994

Reconstitution of transcriptional activation domains by reiteration of short peptide segments reveals the modular organization of a glutamine-rich activation domain is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.14.9.6056
P932PMC publication ID359132
P698PubMed publication ID8065339
P5875ResearchGate publication ID15134587

P2093author name stringM Tanaka
W Herr
P2860cites workPattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activatorQ24563645
Crystal structures of two viral peptides in complex with murine MHC class I H-2KbQ27642080
Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 AQ27660274
The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selectionQ27729346
Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modulesQ27731280
Use of T7 RNA polymerase to direct expression of cloned genesQ27860692
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteinsQ27861094
Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeastQ27933378
The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domainsQ28114875
The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomainQ28283991
Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activationQ28303864
Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoterQ28620733
Transcription factors: structural families and principles of DNA recognitionQ29615317
Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylationQ29618286
How eukaryotic transcriptional activators workQ29618289
Mechanism of transcriptional activation by Sp1: evidence for coactivatorsQ29620214
Factors involved in specific transcription by mammalian RNA polymerase II: identification of general transcription factor TFIIG.Q33907808
Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cellsQ33919791
The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcriptionQ33919795
Mutants of GAL4 protein altered in an activation functionQ34166478
Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 proteinQ34172416
A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressorQ34194676
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.Q34350288
DNA recognition by GAL4: structure of a protein-DNA complex.Q34372191
A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activationQ34920038
The Oct-2 glutamine-rich and proline-rich activation domains can synergize with each other or duplicates of themselves to activate transcriptionQ36665493
Affinity purification of sequence-specific DNA binding proteinsQ37394403
The acidic activation domains of the GCN4 and GAL4 proteins are not alpha helical but form beta sheetsQ38321418
Polyomavirus enhancer contains multiple redundant sequence elements that activate both DNA replication and gene expressionQ40665948
Discrete elements within the SV40 enhancer region display different cell-specific enhancer activities.Q41338677
Transcriptional activation modulated by homopolymeric glutamine and proline stretchesQ41488003
Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positionsQ41543354
The SV40 enhancer contains two distinct levels of organizationQ42117036
A TBP complex essential for transcription from TATA-less but not TATA-containing RNA polymerase III promoters is part of the TFIIIB fraction.Q42457249
Coactivators for a proline-rich activator purified from the multisubunit human TFIID complexQ42468497
Purification and characterization of the carboxyl-terminal transactivation domain of Vmw65 from herpes simplex virus type 1Q44595851
The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequenceQ45233544
Activation of the U2 snRNA promoter by the octamer motif defines a new class of RNA polymerase II enhancer elementsQ45345558
Structural studies of the acidic transactivation domain of the Vmw65 protein of herpes simplex virus using 1H NMRQ45879786
Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE.Q50320384
A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cellsQ58989803
A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox proteinQ58989818
Critical structural elements of the VP16 transcriptional activation domainQ67912152
The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHCQ68045564
The Oct-2 protein binds cooperatively to adjacent octamer sitesQ69427021
The SV40 enhancer can be dissected into multiple segments, each with a different cell type specificityQ69816464
Cooperativity and hierarchical levels of functional organization in the SV40 enhancerQ69836859
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)6056-6067
P577publication date1994-09-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleReconstitution of transcriptional activation domains by reiteration of short peptide segments reveals the modular organization of a glutamine-rich activation domain
P478volume14