scholarly article | Q13442814 |
P356 | DOI | 10.1007/978-1-60327-248-3_12 |
P8608 | Fatcat ID | release_vlplpelum5dbje32yw36gtceim |
P932 | PMC publication ID | 2394199 |
P698 | PubMed publication ID | 18470646 |
P5875 | ResearchGate publication ID | 5380248 |
P2093 | author name string | Robert G Hawley | |
Teresa S Hawley | |||
Ali Ramezani | |||
P2860 | cites work | Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system | Q24628961 |
The protein CTCF is required for the enhancer blocking activity of vertebrate insulators | Q28142800 | ||
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1 | Q28210584 | ||
Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration | Q28242708 | ||
The HOX11 homeobox-containing gene of human leukemia immortalizes murine hematopoietic precursors. | Q53475878 | ||
Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis. | Q53869055 | ||
Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking. | Q54662841 | ||
Small changes in expression affect predisposition to tumorigenesis | Q59115695 | ||
The human cytomegalovirus major immediate early promoter can be trans-activated by adenovirus early proteins | Q64379058 | ||
Long- and short-lived murine hematopoietic stem cell clones individually identified with retroviral integration markers | Q68809190 | ||
Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein | Q74171668 | ||
Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood | Q77684631 | ||
Murine leukemia induced by retroviral gene marking | Q77975543 | ||
Hematopoietic stem cells | Q79399529 | ||
Species- and cell type-specific requirements for cellular transformation | Q80482709 | ||
EVI1 and hematopoietic disorders: history and perspectives | Q28284034 | ||
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector | Q29547503 | ||
Production of high-titer helper-free retroviruses by transient transfection | Q29547802 | ||
A third-generation lentivirus vector with a conditional packaging system | Q29616120 | ||
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo | Q29616612 | ||
Transcription start regions in the human genome are favored targets for MLV integration | Q29618456 | ||
Multiparameter flow cytometry of fluorescent protein reporters | Q31049416 | ||
Detection and enrichment of hematopoietic stem cells by side population phenotype | Q33198498 | ||
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia | Q33330210 | ||
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. | Q33643620 | ||
Development of a self-inactivating lentivirus vector. | Q33784841 | ||
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery | Q33786060 | ||
Mobilization and mechanism of transcription of integrated self-inactivating lentiviral vectors | Q33843471 | ||
Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector | Q33856071 | ||
Clonal contributions of small numbers of retrovirally marked hematopoietic stem cells engrafted in unirradiated neonatal W/Wv mice | Q33862662 | ||
Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities | Q34067751 | ||
RNA 3' readthrough of oncoretrovirus and lentivirus: implications for vector safety and efficacy | Q34342598 | ||
A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila | Q34352447 | ||
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors | Q34419716 | ||
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. | Q34508425 | ||
Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells | Q34614346 | ||
Progress toward vector design for hematopoietic stem cell gene therapy | Q34729423 | ||
RTCGD: retroviral tagged cancer gene database | Q34923778 | ||
American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells | Q35195407 | ||
A chromatin insulator protects retrovirus vectors from chromosomal position effects | Q35198059 | ||
Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells | Q35604467 | ||
The role of signal transducer and activator of transcription factors in leukemogenesis | Q35628327 | ||
Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells | Q35847760 | ||
Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells | Q35848227 | ||
Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis | Q35848246 | ||
Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque | Q35848273 | ||
Pseudotransduction of hepatocytes by using concentrated pseudotyped vesicular stomatitis virus G glycoprotein (VSV-G)-Moloney murine leukemia virus-derived retrovirus vectors: comparison of VSV-G and amphotropic vectors for hepatic gene transfer | Q35859108 | ||
Stem cell clonality and genotoxicity in hematopoietic cells: gene activation side effects should be avoidable. | Q35929299 | ||
Characterization of the chicken beta-globin insulator | Q35956059 | ||
Retrovirus silencer blocking by the cHS4 insulator is CTCF independent | Q36079373 | ||
Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer | Q36231835 | ||
Chromatin boundaries and chromatin domains. | Q36238580 | ||
Tumor suppressor genetics | Q36252762 | ||
Molecular genetics of acute lymphoblastic leukemia | Q36254588 | ||
Genome-wide analysis of retroviral DNA integration | Q36263002 | ||
Silencing and variegation of gammaretrovirus and lentivirus vectors | Q36301560 | ||
Progenitor cell hyperplasia with rare development of myeloid leukemia in interleukin 11 bone marrow chimeras | Q36362432 | ||
Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors. | Q36424249 | ||
Genotoxicity of retroviral integration in hematopoietic cells. | Q36453658 | ||
Retrovirus vectors: toward the plentivirus? | Q36457016 | ||
Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells | Q36506251 | ||
Stable gammaretroviral vector expression during embryonic stem cell-derived in vitro hematopoietic development | Q36665437 | ||
Integrated self-inactivating lentiviral vectors produce full-length genomic transcripts competent for encapsidation and integration | Q36684330 | ||
Identification of a common ecotropic viral integration site, Evi-1, in the DNA of AKXD murine myeloid tumors | Q36780634 | ||
A safe packaging line for gene transfer: separating viral genes on two different plasmids | Q36865708 | ||
Development of retrovirus vectors useful for expressing genes in cultured murine embryonal cells and hematopoietic cells in vivo | Q36873087 | ||
Generation of packaging cell lines for pseudotyped retroviral vectors of the G protein of vesicular stomatitis virus by using a modified tetracycline inducible system | Q37323864 | ||
Thrombopoietic potential and serial repopulating ability of murine hematopoietic stem cells constitutively expressing interleukin 11. | Q37335536 | ||
Tumorigenesis by slow-transforming retroviruses--an update | Q38012047 | ||
The cHS4 insulator increases the probability of retroviral expression at random chromosomal integration sites. | Q39591112 | ||
Suppression of clonal dominance in cultured human lymphoid cells by addition of the cHS4 insulator to a lentiviral vector | Q40171207 | ||
Overcoming promoter competition in packaging cells improves production of self-inactivating retroviral vectors | Q40269711 | ||
Transient gene expression by nonintegrating lentiviral vectors | Q40300665 | ||
Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression | Q40365103 | ||
Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells | Q40492460 | ||
Sustained phenotypic correction of hemophilia a mice following oncoretroviral-mediated expression of a bioengineered human factor VIII gene in long-term hematopoietic repopulating cells | Q40499239 | ||
Self-inactivating retroviral vectors with improved RNA processing. | Q40515056 | ||
High-level sustained transgene expression in human embryonic stem cells using lentiviral vectors | Q40610397 | ||
Performance- and safety-enhanced lentiviral vectors containing the human interferon-beta scaffold attachment region and the chicken beta-globin insulator | Q40670749 | ||
Kinetic analyses of stability of simple and complex retroviral vectors | Q40728863 | ||
Fibronectin fragment CH-296 inhibits apoptosis and enhances ex vivo gene transfer by murine retrovirus and human lentivirus vectors independent of viral tropism in nonhuman primate CD34+ cells | Q40818099 | ||
Lentiviral vectors for enhanced gene expression in human hematopoietic cells | Q40841789 | ||
Insertional mutagenesis and the transformation of hematopoietic stem cells. | Q40852921 | ||
Establishment of a novel factor-dependent myeloid cell line from primary cultures of mouse bone marrow | Q41703550 | ||
Recombinant retroviruses pseudotyped with the vesicular stomatitis virus G glycoprotein mediate both stable gene transfer and pseudotransduction in human peripheral blood lymphocytes | Q42798184 | ||
Comparative analysis of retroviral vector expression in mouse embryonal carcinoma cells | Q44022852 | ||
Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis | Q45855676 | ||
Lentiviral vectors pseudotyped with murine ecotropic envelope: increased biosafety and convenience in preclinical research | Q45857905 | ||
Versatile retroviral vectors for potential use in gene therapy | Q45867146 | ||
Gene therapy insertional mutagenesis insights | Q45871758 | ||
Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia | Q45873554 | ||
Double-copy bicistronic retroviral vector platform for gene therapy and tissue engineering: application to melanoma vaccine development | Q45884879 | ||
Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice | Q45885733 | ||
Leukemic predisposition of mice transplanted with gene-modified hematopoietic precursors expressing flt3 ligand | Q45889081 | ||
Developmental potential and dynamic behavior of hematopoietic stem cells. | Q52261166 | ||
P407 | language of work or name | English | Q1860 |
P921 | main subject | genotoxicity | Q1009245 |
P304 | page(s) | 183-203 | |
P577 | publication date | 2008-01-01 | |
P1433 | published in | Methods in Molecular Biology | Q15752859 |
P1476 | title | Reducing the genotoxic potential of retroviral vectors | |
P478 | volume | 434 |
Q37021156 | Combinatorial incorporation of enhancer-blocking components of the chicken beta-globin 5'HS4 and human T-cell receptor alpha/delta BEAD-1 insulators in self-inactivating retroviral vectors reduces their genotoxic potential |
Q36956171 | Comparison of human coagulation factor VIII expression directed by cytomegalovirus and mammary gland-specific promoters in HC11 cells and transgenic mice |
Q37268992 | Correction of murine hemophilia A following nonmyeloablative transplantation of hematopoietic stem cells engineered to encode an enhanced human factor VIII variant using a safety-augmented retroviral vector |
Q55417064 | Factor VIII delivered by haematopoietic stem cell-derived B cells corrects the phenotype of haemophilia A mice. |
Q34539879 | Immunization delivered by lentiviral vectors for cancer and infectious diseases |
Q35755987 | Strategies to insulate lentiviral vector-expressed transgenes |
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